421
Views
51
CrossRef citations to date
0
Altmetric
Reviews

Activation of lecithin: cholesterol acyltransferase by HDL ApoA-I central helices

, &
Pages 113-124 | Published online: 18 Jan 2017

Keep up to date with the latest research on this topic with citation updates for this article.

Read on this site (2)

G. Chandrasekhar, P. Chandra Sekar, E. Srinivasan, A. Amarnath, H. Pengyong & R. Rajasekaran. (2022) Molecular simulation unravels the amyloidogenic misfolding of nascent ApoA1 protein, driven by deleterious point mutations occurring in between 170–178 hotspot region. Journal of Biomolecular Structure and Dynamics 40:23, pages 13278-13290.
Read now
Juan Ye, Qiu-yun Luo, Xue-ping Wang, Zhen-yi Liu, Mei-xian Chen, Hao Huang & Lin Zhang. (2019) Serum Apolipoprotein A-I Combined With C-Reactive Protein Serves As A Novel Prognostic Stratification System For Colorectal Cancer. Cancer Management and Research 11, pages 9265-9276.
Read now

Articles from other publishers (49)

Haoran Chen, Xiaofen Qi, Kaifang Guan, Rongchun Wang, Qiming Li & Ying Ma. (2023) Tandem mass tag-based quantitative proteomics analysis reveals the effects of the α-lactalbumin peptides GINY and DQW on lipid deposition and oxidative stress in HepG2 cells. Journal of Dairy Science 106:4, pages 2271-2288.
Crossref
Julia T. Stadler, Hubert Scharnagl, Christian Wadsack & Gunther Marsche. (2023) Preeclampsia Affects Lipid Metabolism and HDL Function in Mothers and Their Offspring. Antioxidants 12:4, pages 795.
Crossref
Domenico Sergi, Enrico Zauli, Veronica Tisato, Paola Secchiero, Giorgio Zauli & Carlo Cervellati. (2023) Lipids at the Nexus between Cerebrovascular Disease and Vascular Dementia: The Impact of HDL-Cholesterol and Ceramides. International Journal of Molecular Sciences 24:5, pages 4403.
Crossref
Hongliang Gao, Jing Wu, Zhenyu Sun, Furong Zhang, Tianshu Shi, Ke Lu, Dongfu Qian, Zicheng Yin, Yinjuan Zhao, Jian Qin & Bin Xue. (2022) Influence of lecithin cholesterol acyltransferase alteration during different pathophysiologic conditions: A 45 years bibliometrics analysis. Frontiers in Pharmacology 13.
Crossref
Stanislav Kotlyarov. (2022) High-Density Lipoproteins: A Role in Inflammation in COPD. International Journal of Molecular Sciences 23:15, pages 8128.
Crossref
Eduardo Z. Romo & Angela M. Zivkovic. (2022) Glycosylation of HDL-Associated Proteins and Its Implications in Cardiovascular Disease Diagnosis, Metabolism and Function. Frontiers in Cardiovascular Medicine 9.
Crossref
Roopa Mehta, Daniel Elías-López, Alexandro J. Martagón, Oscar A Pérez-Méndez, Maria Luisa Ordóñez Sánchez, Yayoi Segura, Maria Teresa Tusié & Carlos A. Aguilar-Salinas. (2021) LCAT deficiency: a systematic review with the clinical and genetic description of Mexican kindred. Lipids in Health and Disease 20:1.
Crossref
Steve Pedrini, Pratishtha Chatterjee, Eugene Hone & Ralph N. Martins. (2020) High‐density lipoprotein‐related cholesterol metabolism in Alzheimer’s disease. Journal of Neurochemistry 159:2, pages 343-377.
Crossref
Takuya Iino, Ryuji Toh, Manabu Nagao, Masakazu Shinohara, Amane Harada, Katsuhiro Murakami, Yasuhiro Irino, Makoto Nishimori, Sachiko Yoshikawa, Yutaro Seto, Tatsuro Ishida & Ken-ichi Hirata. (2021) Effects of Elaidic Acid on HDL Cholesterol Uptake Capacity. Nutrients 13:9, pages 3112.
Crossref
Julia T. Stadler, Christian Wadsack & Gunther Marsche. (2021) Fetal High-Density Lipoproteins: Current Knowledge on Particle Metabolism, Composition and Function in Health and Disease. Biomedicines 9:4, pages 349.
Crossref
Shrushti Shah, Tiffany Fillier, Thu Huong Pham, Raymond Thomas & Sukhinder Kaur Cheema. (2021) Intraperitoneal Administration of Short-Chain Fatty Acids Improves Lipid Metabolism of Long–Evans Rats in a Sex-Specific Manner. Nutrients 13:3, pages 892.
Crossref
Mateo Amaya-Montoya, Jairo A. Pinzón-Cortés, Lina S. Silva-Bermúdez, Daniel Ruiz-Manco, Maria C. Pérez-Matos, Mario A. Jiménez-Mora & Carlos O. Mendivil. (2020) ApoE and apoC-III-defined HDL subtypes: a descriptive study of their lecithin cholesterol acyl transferase and cholesteryl ester transfer protein content and activity. Lipids in Health and Disease 19:1.
Crossref
Julia T. Stadler & Gunther Marsche. (2020) Obesity-Related Changes in High-Density Lipoprotein Metabolism and Function. International Journal of Molecular Sciences 21:23, pages 8985.
Crossref
Megan Shelby, Deepshika Gilbile, Thomas Grant, William Bauer, Brent Segelke, Wei He, Angela Evans, Natalia Crespo, Pontus Fischer, Tim Pakendorf, Vincent Hennicke, Mark Hunter, Alex Batyuk, Miriam Barthelmess, Alke Meents, Tonya Kuhl, Matthias Frank & Matthew Coleman. (2020) Crystallization of ApoA1 and ApoE4 Nanolipoprotein Particles and Initial XFEL-Based Structural Studies. Crystals 10:10, pages 886.
Crossref
Lolita Piersimoni & Andrea Sinz. (2020) Cross-linking/mass spectrometry at the crossroads. Analytical and Bioanalytical Chemistry 412:24, pages 5981-5987.
Crossref
Kelly Manthei, Louise Chang, John Tesmer & Melanie Ohi. (2020) CryoEM Analysis of Lecithin:Cholesterol Acyltransferase in Complex with High-Density Lipoprotein Particles. Microscopy and Microanalysis 26:S2, pages 576-577.
Crossref
Kelly A. Manthei, Dhabaleswar Patra, Christopher J. Wilson, Maria V. Fawaz, Lolita Piersimoni, Jenny Capua Shenkar, Wenmin Yuan, Philip C. Andrews, John R. Engen, Anna Schwendeman, Melanie D. Ohi & John J. G. Tesmer. (2020) Structural analysis of lecithin:cholesterol acyltransferase bound to high density lipoprotein particles. Communications Biology 3:1.
Crossref
Ahmet Yalcinkaya, Selma Unal & Yesim Oztas. (2019) Altered HDL particle in sickle cell disease: decreased cholesterol content is associated with hemolysis, whereas decreased Apolipoprotein A1 is linked to inflammation. Lipids in Health and Disease 18:1.
Crossref
Boby Mathew, Krishnamachari Srinivasan, Johnson Pradeep, Tinku Thomas, ShakuntalaKandikuppa Murthy & AmitKumar Mandal. (2019) Downregulation of apolipoprotein A-IV in plasma & impaired reverse cholesterol transport in individuals with recent acts of deliberate self-harm. Indian Journal of Medical Research 150:4, pages 365.
Crossref
Julia Modesto Vicente, Caio Jordão Teixeira, Junia Carolina Santos-Silva, Dailson Nogueira de Souza, Natália Tobar, Fabiola Sales Furtuoso, Isabel Gouveia Adabo, Frhancielly Shirley Sodré, Gilson Murata, Silvana Bordin & Gabriel Forato Anhê. (2019) The absence of lactation after pregnancy induces long-term lipid accumulation in maternal liver of mice. Life Sciences 217, pages 261-270.
Crossref
Saleh Rahmati-Ahmadabad, Hossein Shirvani, Abbass Ghanbari-Niaki & Fatemeh Rostamkhani. (2018) The effects of high-intensity interval training on reverse cholesterol transport elements: A way of cardiovascular protection against atherosclerosis. Life Sciences 209, pages 377-382.
Crossref
Christopher J. Wilson, Madhurima Das, Shobini Jayaraman, Olga Gursky & John R. Engen. (2018) Effects of Disease-Causing Mutations on the Conformation of Human Apolipoprotein A-I in Model Lipoproteins. Biochemistry 57:30, pages 4583-4596.
Crossref
Nasser M. Al-Daghri, Kaiser Wani, Shaun Sabico, Spiro D. Garbis, George P. Chrousos, Osama E. Amer, Mohammed Ghouse Ahmed Ansari, Yousef Al-Saleh, Naji J. Aljohani, Omar S. Al-Attas & Majed S. Alokail. (2018) Sex-specific expression of apolipoprotein levels following replenishment of vitamin D. The Journal of Steroid Biochemistry and Molecular Biology 180, pages 129-136.
Crossref
Zhimin Zhang, Peimao Li, Dafeng Lin, Dianpeng Wang & Yanfang Zhang. (2018) Proteome analysis of the potential serum biomarkers for chronic benzene poisoning. Environmental Toxicology and Pharmacology 60, pages 157-164.
Crossref
Marco G. Casteleijn, Petteri Parkkila, Tapani Viitala & Artturi Koivuniemi. (2018) Interaction of lecithin:cholesterol acyltransferase with lipid surfaces and apolipoprotein A-I-derived peptides. Journal of Lipid Research 59:4, pages 670-683.
Crossref
Kelly A. Manthei, Joomi Ahn, Alisa Glukhova, Wenmin Yuan, Christopher Larkin, Taylor D. Manett, Louise Chang, James A. Shayman, Milton J. Axley, Anna Schwendeman & John J.G. Tesmer. (2017) A retractable lid in lecithin:cholesterol acyltransferase provides a structural mechanism for activation by apolipoprotein A-I. Journal of Biological Chemistry 292:49, pages 20313-20327.
Crossref
Päivi Sirniö, Juha P. Väyrynen, Kai Klintrup, Jyrki Mäkelä, Markus J. Mäkinen, Tuomo J. Karttunen & Anne Tuomisto. (2017) Decreased serum apolipoprotein A1 levels are associated with poor survival and systemic inflammatory response in colorectal cancer. Scientific Reports 7:1.
Crossref
Stefan Bibow, Yevhen Polyhach, Cédric Eichmann, Celestine N Chi, Julia Kowal, Stefan Albiez, Robert A McLeod, Henning Stahlberg, Gunnar Jeschke, Peter Güntert & Roland Riek. (2016) Solution structure of discoidal high-density lipoprotein particles with a shortened apolipoprotein A-I. Nature Structural & Molecular Biology 24:2, pages 187-193.
Crossref
Jens B. Simonsen. (2016) Evaluation of reconstituted high-density lipoprotein (rHDL) as a drug delivery platform – a detailed survey of rHDL particles ranging from biophysical properties to clinical implications. Nanomedicine: Nanotechnology, Biology and Medicine 12:7, pages 2161-2179.
Crossref
Xiaodong Gu, Zhiping Wu, Ying Huang, Matthew A. Wagner, Camelia Baleanu-Gogonea, Ryan A. Mehl, Jennifer A. Buffa, Anthony J. DiDonato, Leah B. Hazen, Paul L. Fox, Valentin Gogonea, John S. Parks, Joseph A. DiDonato & Stanley L. Hazen. (2016) A Systematic Investigation of Structure/Function Requirements for the Apolipoprotein A-I/Lecithin Cholesterol Acyltransferase Interaction Loop of High-density Lipoprotein. Journal of Biological Chemistry 291:12, pages 6386-6395.
Crossref
Valentin Gogonea. (2016) Structural Insights into High Density Lipoprotein: Old Models and New Facts. Frontiers in Pharmacology 6.
Crossref
Maryam Zamanian-Daryoush & Joseph A. DiDonato. (2015) Apolipoprotein A-I and Cancer. Frontiers in Pharmacology 6.
Crossref
Juan Salazar, Luis Carlos Olivar, Eduardo Ramos, Mervin Chávez-Castillo, Joselyn Rojas & Valmore Bermúdez. (2015) Dysfunctional High-Density Lipoprotein: An Innovative Target for Proteomics and Lipidomics. Cholesterol 2015, pages 1-22.
Crossref
Nikolaos N. Louros, Paraskevi L. Tsiolaki, Michael D.W. Griffin, Geoffrey J. Howlett, Stavros J. Hamodrakas & Vassiliki A. Iconomidou. (2015) Chameleon ‘aggregation-prone’ segments of apoA-I: A model of amyloid fibrils formed in apoA-I amyloidosis. International Journal of Biological Macromolecules 79, pages 711-718.
Crossref
Jere P. Segrest, Martin K. Jones, Andrea Catte & Saravana P. Thirumuruganandham. (2015) A robust all-atom model for LCAT generated by homology modeling. Journal of Lipid Research 56:3, pages 620-634.
Crossref
Irina N. Gorshkova, Xiaohu Mei & David Atkinson. (2014) Binding of human apoA-I[K107del] variant to TG-rich particles: implications for mechanisms underlying hypertriglyceridemia. Journal of Lipid Research 55:9, pages 1876-1885.
Crossref
Luke J. Leman, Bruce E. Maryanoff & M. Reza Ghadiri. (2013) Molecules That Mimic Apolipoprotein A-I: Potential Agents for Treating Atherosclerosis. Journal of Medicinal Chemistry 57:6, pages 2169-2196.
Crossref
Lusana Ahsan, Alice F. Ossoli, Lita Freeman, Boris Vaisman, Marcelo J. Amar, Robert D. Shamburek & Alan T. Remaley. 2014. The HDL Handbook. The HDL Handbook 159 194 .
Chengjian Tu, Jun Li, Xiaosheng Jiang, Lowell G. Sheflin, Bruce A. Pfeffer, Matthew Behringer, Steven J. Fliesler & Jun Qu. (2013) Ion-current-based Proteomic Profiling of the Retina in a Rat Model of Smith-Lemli-Opitz Syndrome. Molecular & Cellular Proteomics 12:12, pages 3583-3598.
Crossref
S.L. Aguilar-Espinosa, P. Mendoza-Espinosa, B. Delgado-Coello & J. Mas-Oliva. (2013) Lecithin cholesterol acyltransferase (LCAT) activity in the presence of Apo-AI-derived peptides exposed to disorder–order conformational transitions. Biochemical and Biophysical Research Communications 441:2, pages 469-475.
Crossref
Alexander D. Dergunov. (2013) Sequence-specific apolipoprotein A-I effects on lecithin:cholesterol acyltransferase activity. Molecular and Cellular Biochemistry 378:1-2, pages 283-290.
Crossref
Li Jin Pu, Lin Lu, Rui Yan Zhang, Run Du, Ying Shen, Qi Zhang, Zheng Kun Yang, Qiu Jing Chen & Wei Feng Shen. (2013) Glycation of Apoprotein A-I Is Associated With Coronary Artery Plaque Progression in Type 2 Diabetic Patients. Diabetes Care 36:5, pages 1312-1320.
Crossref
Olga Gursky. (2013) Crystal Structure of Δ(185–243)ApoA-I Suggests a Mechanistic Framework for the Protein Adaptation to the Changing Lipid Load in Good Cholesterol: From Flatland to Sphereland via Double Belt, Belt Buckle, Double Hairpin and Trefoil/Tetrafoil. Journal of Molecular Biology 425:1, pages 1-16.
Crossref
Xing Liu, Rong Suo, Sheng-Lin Xiong, Qing-Hai Zhang & Guang-Hui Yi. (2013) HDL drug carriers for targeted therapy. Clinica Chimica Acta 415, pages 94-100.
Crossref
Palaniappan Sevugan Chetty, Leland Mayne, Zhong-Yuan Kan, Sissel Lund-Katz, S. Walter Englander & Michael C. Phillips. (2012) Apolipoprotein A-I helical structure and stability in discoidal high-density lipoprotein (HDL) particles by hydrogen exchange and mass spectrometry. Proceedings of the National Academy of Sciences 109:29, pages 11687-11692.
Crossref
Yaoyong Wang (王耀勇)Jinko Sawashita (澤下仁子)Jinze Qian (钱金泽)Beiru Zhang (张蓓茹)Xiaoying Fu (付笑影)Geng Tian (田耕)Lei Chen (陈磊)Masayuki Mori (森 政之)Keiichi Higuchi (樋口京一). (2011) ApoA-I deficiency in mice is associated with redistribution of apoA-II and aggravated AApoAII amyloidosis. Journal of Lipid Research 52:8, pages 1461-1470.
Crossref
Monica Gomaraschi, Laura Obici, Sara Simonelli, Gina Gregorini, Alessandro Negrinelli, Giampaolo Merlini, Guido Franceschini & Laura Calabresi. (2011) Effect of the amyloidogenic L75P apolipoprotein A-I variant on HDL subpopulations. Clinica Chimica Acta 412:13-14, pages 1262-1265.
Crossref
Sakiyo Asada, Masayuki Kuroda, Yasuyuki Aoyagi, Hideaki Bujo, Shigeaki Tanaka, Shunichi Konno, Masami Tanio, Itsuko Ishii, Masayuki Aso & Yasushi Saito. (2011) Disturbed apolipoprotein A-I-containing lipoproteins in fish-eye disease are improved by the lecithin:cholesterol acyltransferase produced by gene-transduced adipocytes in vitro. Molecular Genetics and Metabolism 102:2, pages 229-231.
Crossref
Shaila Bhat, Mary G. Sorci-Thomas, Laura Calabresi, Michael P. Samuel & Michael J. Thomas. (2010) Conformation of Dimeric Apolipoprotein A-I Milano on Recombinant Lipoprotein Particles. Biochemistry 49:25, pages 5213-5224.
Crossref

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.