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Lysophosphatidic acid effects on atherosclerosis and thrombosis

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Pages 413-426 | Published online: 18 Jan 2017

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Geon-Ho Lee, Jayeon Cheon, Donghee Kim & Hee-Sook Jun. (2022) Lysophosphatidic Acid Promotes Epithelial–Mesenchymal Transition in Kidney Epithelial Cells via the LPAR1/MAPK-AKT/KLF5 Signaling Pathway in Diabetic Nephropathy. International Journal of Molecular Sciences 23:18, pages 10497.
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Theodosis Kalamatianos, Evangelos Drosos, Christiana Magkrioti, Ioanna Nikitopoulou, Christos Koutsarnakis, Anastasia Kotanidou, George P. Paraskevas, Vassilis Aidinis & George Stranjalis. (2022) Autotaxin Activity in Chronic Subdural Hematoma: A Prospective Clinical Study. Diagnostics 12:8, pages 1865.
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Thomas Duflot, Ly Tu, Matthieu Leuillier, Hind Messaoudi, Déborah Groussard, Guillaume Feugray, Saïda Azhar, Raphaël Thuillet, Fabrice Bauer, Marc Humbert, Vincent Richard, Christophe Guignabert & Jérémy Bellien. (2021) Preventing the Increase in Lysophosphatidic Acids: A New Therapeutic Target in Pulmonary Hypertension?. Metabolites 11:11, pages 784.
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Susmita Bhattarai, Sudha Sharma, Hosne Ara, Utsab Subedi, Grace Sun, Chun Li, Md. Shenuarin Bhuiyan, Christopher Kevil, William P. Armstrong, Miles T. Minvielle, Sumitra Miriyala & Manikandan Panchatcharam. (2021) Disrupted Blood‐Brain Barrier and Mitochondrial Impairment by Autotaxin–Lysophosphatidic Acid Axis in Postischemic Stroke. Journal of the American Heart Association 10:18.
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Amy O'Regan, Colm J. O'Brien & Sarah B. Eivers. (2021) The lysophosphatidic acid axis in fibrosis: Implications for glaucoma. Wound Repair and Regeneration 29:4, pages 613-626.
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Takuro Miyazaki & Akira Miyazaki. (2021) Hypercholesterolemia and Lymphatic Defects: The Chicken or the Egg?. Frontiers in Cardiovascular Medicine 8.
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Shefali Talwar, Aayush Kant, Tina Xu, Vivek B. Shenoy & Richard K. Assoian. (2021) Mechanosensitive smooth muscle cell phenotypic plasticity emerging from a null state and the balance between Rac and Rho. Cell Reports 35:3, pages 109019.
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Irina N. Gladkikh, Oksana V. Sintsova, Elena V. Leychenko & Sergey A. Kozlov. (2021) TRPV1 Ion Channel: Structural Features, Activity Modulators, and Therapeutic Potential. Biochemistry (Moscow) 86:S1, pages S50-S70.
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Thieu X. Phan, Hoai T. Ton, Hajnalka Gulyás, Róbert Pórszász, Attila Tóth, Rebekah Russo, Matthew W. Kay, Niaz Sahibzada & Gerard P. Ahern. (2020) TRPV1 expressed throughout the arterial circulation regulates vasoconstriction and blood pressure. The Journal of Physiology 598:24, pages 5639-5659.
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Qian Zhang, Xiao Yang, Qian Wang, Yiwen Zhang, Peng Gao, Zuojing Li, Ran Liu, Huarong Xu, Kaishun Bi & Qing Li. (2020) “Modeling−Prediction” Strategy for Deep Profiling of Lysophosphatidic Acids by Liquid Chromatography−Mass Spectrometry: Exploration Biomarkers of Breast Cancer. Journal of Chromatography A 1634, pages 461634.
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Tiewei Li, Rui Peng, Fang Wang, Lu Hua, Sheng Liu, Zhiyan Han, Jianqiu Pei, Shengqiang Pei, Zhenwen Zhao, Xin Jiang & Xi Chen. (2020) Lysophosphatidic acid promotes thrombus stability by inducing rapid formation of neutrophil extracellular traps: A new mechanism of thrombosis. Journal of Thrombosis and Haemostasis 18:8, pages 1952-1964.
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Thomas Öhlinger, Ernst W. Müllner, Magdalena Fritz, Thomas Sauer, Maike Werning, David M. Baron & Ulrich Salzer. (2020) Lysophosphatidic acid-induced pro-thrombotic phosphatidylserine exposure and ionophore-induced microvesiculation is mediated by the scramblase TMEM16F in erythrocytes. Blood Cells, Molecules, and Diseases 83, pages 102426.
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Aaron H. Wasserman, Manigandan Venkatesan & Aitor Aguirre. (2020) Bioactive Lipid Signaling in Cardiovascular Disease, Development, and Regeneration. Cells 9:6, pages 1391.
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Ying Zhou, Peter J. Little, Hang T. Ta, Suowen Xu & Danielle Kamato. (2019) Lysophosphatidic acid and its receptors: pharmacology and therapeutic potential in atherosclerosis and vascular disease. Pharmacology & Therapeutics 204, pages 107404.
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Linmu Chen, Jun Zhang, Xi Yang, Yan Liu, Xiao Deng & Chao Yu. (2019) Lysophosphatidic acid decreased macrophage foam cell migration correlated with downregulation of fucosyltransferase 8 via HNF1α. Atherosclerosis 290, pages 19-30.
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Yingfei Yan, Zhifeng Du, Chang Chen, Jiaxin Li, Xiang Xiong, Yang Zhang & Hongliang Jiang. (2019) Lysophospholipid profiles of apolipoprotein E-deficient mice reveal potential lipid biomarkers associated with atherosclerosis progression using validated UPLC-QTRAP-MS/MS-based lipidomics approach. Journal of Pharmaceutical and Biomedical Analysis 171, pages 148-157.
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Akira Sato, Keiju Nakazawa, Ayano Sugawara, Yoji Yamazaki & Keiichi Ebina. (2018) The interaction of β2-glycoprotein I with lysophosphatidic acid in platelet aggregation and blood clotting. Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics 1866:12, pages 1232-1241.
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Dawid S Chabowski, Andrew O Kadlec, Karima Ait-Aissa, Joseph C Hockenberry, Paul J Pearson, Andreas M Beyer & David D Gutterman. (2018) Lysophosphatidic acid acts on LPA 1 receptor to increase H 2 O 2 during flow-induced dilation in human adipose arterioles . British Journal of Pharmacology 175:22, pages 4266-4280.
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Ryoko Tsukahara, Hisao Haniu, Yoshikazu Matsuda & Tamotsu Tsukahara. (2018) The AGP-PPARγ axis promotes oxidative stress and diabetic endothelial cell dysfunction. Molecular and Cellular Endocrinology 473, pages 100-113.
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Cheng Li, Ping-ping Liu, Dou-dou Tang, Rong Song, Yi-qing Zhang, Si Lei & Shang-jie Wu. (2018) Targeting the RhoA-ROCK pathway to regulate T-cell homeostasis in hypoxia-induced pulmonary arterial hypertension. Pulmonary Pharmacology & Therapeutics 50, pages 111-122.
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Ning Wu, Wenbo Wang, Min Yi, Siying Cheng & Dongsheng Wang. (2018) Study of the metabolomics characteristics of patients with metabolic syndrome based on liquid chromatography quadrupole time-of-flight mass spectrometry. Annales d'Endocrinologie 79:1, pages 37-44.
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Dong An, Feng Hao, Fuqiang Zhang, Wei Kong, Jerold Chun, Xuemin Xu & Mei-Zhen Cui. (2017) CD14 is a key mediator of both lysophosphatidic acid and lipopolysaccharide induction of foam cell formation. Journal of Biological Chemistry 292:35, pages 14391-14400.
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Linmu Chen, Jun Zhang, Xiao Deng, Yan Liu, Xi Yang, Qiong Wu & Chao Yu. (2017) Lysophosphatidic acid directly induces macrophage-derived foam cell formation by blocking the expression of SRBI. Biochemical and Biophysical Research Communications 491:3, pages 587-594.
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Haixiang Zheng, Yucai Fu, Yusheng Huang, Xinde Zheng, Wei Yu & Wei Wang. (2017) mTOR signaling promotes foam cell formation and inhibits foam cell egress through suppressing the SIRT1 signaling pathway. Molecular Medicine Reports 16:3, pages 3315-3323.
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Quanlin DouFeng HaoLongsheng SunXuemin XuMei-Zhen Cui. (2017) CRE and SRE mediate LPA-induced CCN1 transcription in mouse aortic smooth muscle cells. Canadian Journal of Physiology and Pharmacology 95:3, pages 275-280.
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Ru Li, Jiqing Huang & Juergen Kast. (2015) Identification of Total Reversible Cysteine Oxidation in an Atherosclerosis Model Using a Modified Biotin Switch Assay. Journal of Proteome Research 14:5, pages 2026-2035.
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Masako Nishikawa, Makoto Kurano, Hitoshi Ikeda, Junken Aoki & Yutaka Yatomi. (2015) Lysophosphatidylserine has Bilateral Effects on Macrophages in the Pathogenesis of Atherosclerosis. Journal of Atherosclerosis and Thrombosis 22:5, pages 518-526.
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Marius C. Staiculescu, Francisco I. Ramirez-Perez, Jorge A. Castorena-Gonzalez, Zhongkui Hong, Zhe Sun, Gerald A. Meininger & Luis A. Martinez-Lemus. (2014) Lysophosphatidic acid induces integrin activation in vascular smooth muscle and alters arteriolar myogenic vasoconstriction. Frontiers in Physiology 5.
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Sara A. Knowlden, Tara Capece, Milan Popovic, Timothy J. Chapman, Fariba Rezaee, Minsoo Kim & Steve N. Georas. (2014) Regulation of T Cell Motility In Vitro and In Vivo by LPA and LPA2. PLoS ONE 9:7, pages e101655.
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Anna Jesionowska, Elzbieta Cecerska & Barbara Dolegowska. (2014) Methods for quantifying lysophosphatidic acid in body fluids: A review. Analytical Biochemistry 453, pages 38-43.
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Daniel Dongwei Wu, Fuqiang Zhang, Feng Hao, Jerold Chun, Xuemin Xu & Mei-Zhen Cui. (2014) Matricellular Protein Cyr61 Bridges Lysophosphatidic Acid and Integrin Pathways Leading to Cell Migration. Journal of Biological Chemistry 289:9, pages 5774-5783.
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Izabela Wocławek-Potocka, Paulina Rawińska, Ilona Kowalczyk-Zieba, Dorota Boruszewska, Emilia Sinderewicz, Tomasz Waśniewski & Dariusz Jan Skarzynski. (2014) Lysophosphatidic Acid (LPA) Signaling in Human and Ruminant Reproductive Tract. Mediators of Inflammation 2014, pages 1-14.
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Yutaka Nagura, Nelson H. Tsuno, Ryunosuke Ohkawa, Takahiro Nojiri, Yasunori Tokuhara, Mika Matsuhashi, Yutaka Yatomi & Koki Takahashi. (2013) Inhibition of lysophosphatidic acid increase by prestorage whole blood leukoreduction in autologous CPDA-1 whole blood. Transfusion 53:12, pages 3139-3148.
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Martine Bot, Saskia C.A. de Jager, Luke MacAleese, H. Maxime Lagraauw, Theo J.C. van Berkel, Paul H.A. Quax, Johan Kuiper, Ron M.A. Heeren, Erik A.L. Biessen & Ilze Bot. (2013) Lysophosphatidic acid triggers mast cell-driven atherosclerotic plaque destabilization by increasing vascular inflammation. Journal of Lipid Research 54:5, pages 1265-1274.
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Ioanna Sevastou, Eleanna Kaffe, Marios-Angelos Mouratis & Vassilis Aidinis. (2013) Lysoglycerophospholipids in chronic inflammatory disorders: The PLA2/LPC and ATX/LPA axes. Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids 1831:1, pages 42-60.
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H. Ren, M. Panchatcharam, P. Mueller, D. Escalante-Alcalde, A.J. Morris & S.S. Smyth. (2013) Lipid phosphate phosphatase (LPP3) and vascular development. Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids 1831:1, pages 126-132.
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Jing Shi, Yunzhou Dong, Mei-Zhen Cui & Xuemin Xu. (2013) Lysophosphatidic acid induces increased BACE1 expression and Aβ formation. Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease 1832:1, pages 29-38.
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Takuya Iyoda, Fuqiang Zhang, Longsheng Sun, Feng Hao, Carsten Schmitz-Peiffer, Xuemin Xu & Mei-Zhen Cui. (2012) Lysophosphatidic Acid Induces Early Growth Response-1 (Egr-1) Protein Expression via Protein Kinase Cδ-regulated Extracellular Signal-regulated Kinase (ERK) and c-Jun N-terminal Kinase (JNK) Activation in Vascular Smooth Muscle Cells. Journal of Biological Chemistry 287:27, pages 22635-22642.
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Hélène Plé, Manon Maltais, Aurélie Corduan, Guy Rousseau, François Madore & Patrick Provost. (2017) Alteration of the platelet transcriptome in chronic kidney disease. Thrombosis and Haemostasis 108:10, pages 605-615.
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