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Role of autotaxin and lysophosphatidate in cancer progression and resistance to chemotherapy and radiotherapy

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Pages 313-328 | Published online: 18 Jan 2017

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Efrosini Barbayianni, Victoria Magrioti, Panagiota Moutevelis-Minakakis & George Kokotos. (2013) Autotaxin inhibitors: a patent review. Expert Opinion on Therapeutic Patents 23:9, pages 1123-1132.
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Articles from other publishers (11)

Shuo Wang, Jiang Chen & Xiao-Zhong Guo. (2022) KAI1/CD82 gene and autotaxin-lysophosphatidic acid axis in gastrointestinal cancers . World Journal of Gastrointestinal Oncology 14:8, pages 1388-1405.
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Rackele F. Amaral, Luiz H. M. Geraldo, Marcelo Einicker‐Lamas, Tania C. L. de S. e Spohr, Fabio Mendes & Flavia R. S. Lima. (2020) Microglial lysophosphatidic acid promotes glioblastoma proliferation and migration via LPA 1 receptor . Journal of Neurochemistry 156:4, pages 499-512.
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Petra Grbčić & Mirela Sedić. (2020) Sphingosine 1-Phosphate Signaling and Metabolism in Chemoprevention and Chemoresistance in Colon Cancer. Molecules 25:10, pages 2436.
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Abby L. Parrill. (2016) Reprint of: “Synthetic lipids and their role in defining macromolecular assemblies”. Chemistry and Physics of Lipids 194, pages 149-157.
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Xiaoyun Tang, Matthew G.K. Benesch & David N. Brindley. (2015) Lipid phosphate phosphatases and their roles in mammalian physiology and pathology. Journal of Lipid Research 56:11, pages 2048-2060.
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Abby L. Parrill. (2015) Synthetic lipids and their role in defining macromolecular assemblies. Chemistry and Physics of Lipids 191, pages 38-47.
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Matthew G. K. Benesch, Xiaoyun Tang, Jay Dewald, Wei-Feng Dong, John R. Mackey, Denise G. Hemmings, Todd P. W. McMullen & David N. Brindley. (2015) Tumor-induced inflammation in mammary adipose tissue stimulates a vicious cycle of autotaxin expression and breast cancer progression. The FASEB Journal 29:9, pages 3990-4000.
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Xiaoyun Tang, Matthew G.K. Benesch, Jay Dewald, Yuan Y. Zhao, Neeraj Patwardhan, Webster L. Santos, Jonathan M. Curtis, Todd P.W. McMullen & David N. Brindley. (2014) Lipid phosphate phosphatase-1 expression in cancer cells attenuates tumor growth and metastasis in mice. Journal of Lipid Research 55:11, pages 2389-2400.
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Matthew G.K. Benesch, Yi M. Ko, Todd P.W. McMullen & David N. Brindley. (2014) Autotaxin in the crosshairs: Taking aim at cancer and other inflammatory conditions. FEBS Letters 588:16, pages 2712-2727.
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Matthew G. K. Benesch, Xiaoyun Tang, Tatsuo Maeda, Akira Ohhata, Yuan Y. Zhao, Bernard P. C. Kok, Jay Dewald, Mary Hitt, Jonathan M. Curtis, Todd P. W. McMullen & David N. Brindley. (2014) Inhibition of autotaxin delays breast tumor growth and lung metastasis in mice. The FASEB Journal 28:6, pages 2655-2666.
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David N. Brindley, Fang-Tsyr Lin & Gabor J. Tigyi. (2013) Role of the autotaxin–lysophosphatidate axis in cancer resistance to chemotherapy and radiotherapy. Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids 1831:1, pages 74-85.
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