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Drug Evaluation

The efficacy and safety of ezetimibe coadministered with statin therapy in various patient groups

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Pages 13-41 | Published online: 18 Jan 2017

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Najmeh Ahangari, Majid Ghayour Mobarhan, Amirhossein Sahebkar & Alireza Pasdar. (2018) Molecular aspects of hypercholesterolemia treatment: current perspectives and hopes. Annals of Medicine 50:4, pages 303-311.
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Elizabeth Marrett, Changgeng Zhao, Ning Jackie Zhang, Qiaoyi Zhang, Dena R Ramey, Joanne E Tomassini, Andrew M Tershakovec & David R Neff. (2014) Limitations of real-world treatment with atorvastatin monotherapy for lowering LDL-C in high-risk cardiovascular patients in the US. Vascular Health and Risk Management 10, pages 237-246.
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JoAnne M Foody, Peter P Toth, Andrew M Tershakovec, Thomas Musliner, Joanne E Tomassini, Robert S Lowe, David R Neff & Harry R Davis. (2014) Efficacy and safety of ezetimibe plus atorvastatin therapy. Clinical Lipidology 9:4, pages 441-470.
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Amit K Mistri. (2014) Pharmacological lipid modification therapy following stroke: an update. Clinical Lipidology 9:1, pages 83-89.
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JoAnne M Foody, Peter P Toth, Joanne E Tomassini, Shiva Sajjan, Dena R Ramey, David Neff, Andrew M Tershakovec, Henry Hu & Kaan Tunceli. (2013) Changes in LDL-C levels and goal attainment associated with addition of ezetimibe to simvastatin, atorvastatin, or rosuvastatin compared with titrating statin monotherapy. Vascular Health and Risk Management 9, pages 719-727.
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Articles from other publishers (18)

Elisenda Climent, Ana M. Bea, David Benaiges, Ángel Brea-Hernando, Xavier Pintó, Manuel Suárez-Tembra, Verónica Perea, Núria Plana, Francisco Blanco-Vaca & Juan Pedro-Botet. (2021) LDL Cholesterol Reduction Variability with Different Types and Doses of Statins in Monotherapy or Combined with Ezetimibe. Results from the Spanish Arteriosclerosis Society Dyslipidaemia Registry. Cardiovascular Drugs and Therapy 36:2, pages 301-308.
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Alberico L. Catapano, Michal Vrablik, Yuri Karpov, Baptiste Berthou, Megan Loy & Marie Baccara-Dinet. (2022) A Phase 3 Randomized Controlled Trial to Evaluate Efficacy and Safety of New-Formulation Zenon (Rosuvastatin/Ezetimibe Fixed-Dose Combination) in Primary Hypercholesterolemia Inadequately Controlled by Statins. Journal of Cardiovascular Pharmacology and Therapeutics 27, pages 107424842211382.
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Elisenda Climent, Victoria Marco-Benedí, David Benaiges, Xavier Pintó, Manuel Suárez-Tembra, Núria Plana, Hannia Lafuente, Emilio Ortega-Martínez de Victoria, Ángel Brea-Hernando, Àlex Vila, Fernando Civeira & Juan Pedro-Botet. (2021) Impact of statin therapy on LDL and non-HDL cholesterol levels in subjects with heterozygous familial hypercholesterolaemia. Nutrition, Metabolism and Cardiovascular Diseases 31:5, pages 1594-1603.
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Fadia Tohme Shaya, Krystal Sing, Robert Milam, Fasahath Husain, Michael A. del Aguila & Miraj Y. Patel. (2019) Lipid-Lowering Efficacy of Ezetimibe in Patients with Atherosclerotic Cardiovascular Disease: A Systematic Review and Meta-Analyses. American Journal of Cardiovascular Drugs 20:3, pages 239-248.
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François Schiele, Michel Farnier, Michel Krempf, Eric Bruckert, Jean Ferrières, Denis Angoulvant, Franck Boccara, Jacques Bonnet, Jean-Louis Bonnet, Eric Bruckert, Guillaume Cayla, Marion Chatot, Romain Chopard, Jean-Philippe Collet, Nicolas Danchin, Gregory Ducrocq, Meyer Elbaz, Emile Ferrari, Michel Galinier, Michel Farnier, Jean Ferrières, Edouard Gerbaud, Dominique Guedj, Serge Kownator, Michel Krempf, Gilles Lemesle, Laszlo Levai, Nicolas Mansencal, Jacques Mansourati, Christophe Meune, Olivier Morel, François Paillard, Christophe Piot, Vincent Probst, Etienne Puymirat, François Roubille, Pierre Sabouret, François Schiele & Emmanuel Teiger. (2016) A consensus statement on lipid management after acute coronary syndrome. European Heart Journal: Acute Cardiovascular Care 7:6, pages 532-543.
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Georgios Tsivgoulis, Apostolos Safouris, Dong-Eog Kim & Andrei V. Alexandrov. (2018) Recent Advances in Primary and Secondary Prevention of Atherosclerotic Stroke. Journal of Stroke 20:2, pages 145-166.
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Ulf Landmesser, M John Chapman, Jane K Stock, Pierre Amarenco, Jill J F Belch, Jan Borén, Michel Farnier, Brian A Ference, Stephan Gielen, Ian Graham, Diederick E Grobbee, G Kees Hovingh, Thomas F Lüscher, Massimo F Piepoli, Kausik K Ray, Erik S Stroes, Olov Wiklund, Stephan Windecker, Jose Luis Zamorano, Fausto Pinto, Lale Tokgözoğlu, Jeroen J Bax & Alberico L Catapano. (2018) 2017 Update of ESC/EAS Task Force on practical clinical guidance for proprotein convertase subtilisin/kexin type 9 inhibition in patients with atherosclerotic cardiovascular disease or in familial hypercholesterolaemia. European Heart Journal 39:14, pages 1131-1143.
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Hana Rosolová. (2018) Přínos nové fixní kombinace rosuvastatinu s ezetimibem k léčbě dyslipidemií a ke snížení celkového kardiovaskulárního rizika. Vnitřní lékařství 64:4, pages 457-460.
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Barbora Nussbaumerová & Hana Rosolová. (2018) Epidemiology of hypercholesterolemia. Vnitřní lékařství 64:1, pages 30-37.
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António Miguel Ferreira & Pedro Marques da Silva. (2016) Defining the Place of Ezetimibe/Atorvastatin in the Management of Hyperlipidemia. American Journal of Cardiovascular Drugs 17:3, pages 169-181.
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Evan Stein, Harold Bays, Michael Koren, Rebecca Bakker-Arkema & Charles Bisgaier. (2016) Efficacy and safety of gemcabene as add-on to stable statin therapy in hypercholesterolemic patients. Journal of Clinical Lipidology 10:5, pages 1212-1222.
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Ngoc‐Anh Le, Joanne E. Tomassini, Andrew M. Tershakovec, David R. Neff & Peter W. F. Wilson. (2015) Effect of Switching From Statin Monotherapy to Ezetimibe/Simvastatin Combination Therapy Compared With Other Intensified Lipid‐Lowering Strategies on Lipoprotein Subclasses in Diabetic Patients With Symptomatic Cardiovascular Disease. Journal of the American Heart Association 4:10.
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Olivier Descamps, Joanne E. Tomassini, Jianxin Lin, Adam B. Polis, Arvind Shah, Philippe Brudi, Mary E. Hanson & Andrew M. Tershakovec. (2015) Variability of the LDL-C lowering response to ezetimibe and ezetimibe + statin therapy in hypercholesterolemic patients. Atherosclerosis 240:2, pages 482-489.
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Harold E. Bays, Erluo Chen, Joanne E. Tomassini, Gail McPeters, Adam B. Polis & Joseph Triscari. (2015) Fixed-dose combination ezetimibe+atorvastatin lowers LDL-C equivalent to co-administered components in randomized trials: use of a dose-response model. Fundamental & Clinical Pharmacology 29:2, pages 209-218.
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Alberico L. Catapano, Michel Farnier, JoAnne M. Foody, Peter P. Toth, Joanne E. Tomassini, Philippe Brudi & Andrew M. Tershakovec. (2014) Combination therapy in dyslipidemia: Where are we now?. Atherosclerosis 237:1, pages 319-335.
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Hana Rosolová, Milada Dobiášová, Vladimír Soška, Vladimír Bláha, Richard Češka, Barbora Nussbaumerová, Terezie Pelikánová & Miroslav Souček. (2014) Combined therapy of mixed dyslipidemia in patients with high cardiovascular risk and changes in the lipid target values and atherogenic index of plasma. Cor et Vasa 56:2, pages e133-e139.
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Peter P. Toth, JoAnne M. Foody, Joanne E. Tomassini, Shiva G. Sajjan, Dena R. Ramey, David R. Neff, Andrew M. Tershakovec, X. Henry Hu & Kaan Tunceli. (2014) Therapeutic practice patterns related to statin potency and ezetimibe/simvastatin combination therapies in lowering LDL-C in patients with high-risk cardiovascular disease. Journal of Clinical Lipidology 8:1, pages 107-116.
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Jennifer G. Robinson, Christie M. Ballantyne, Willa A. Hsueh, Jeffrey B. Rosen, Jianxin Lin, Arvind K. Shah, Joanne E. Tomassini, Robert S. Lowe & Andrew M. Tershakovec. (2013) Age, abdominal obesity, and baseline high-sensitivity C-reactive protein are associated with low-density lipoprotein cholesterol, non-high-density lipoprotein cholesterol, and apolipoprotein B responses to ezetimibe/simvastatin and atorvastatin in patients with metabolic syndrome. Journal of Clinical Lipidology 7:4, pages 292-303.
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