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Acta Odontologica Scandinavica Volume 69, 2011 - Issue 3
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Original Article

Treatment of severe drooling with botulinum toxin in amyotrophic lateral sclerosis and Parkinson's disease: Efficacy and possible mechanisms

Eigild Møller Departments of Neurology and Radiology, Bispebjerg Hospital, Copenhagen University Hospital, Copenhagen, Denmark
,
Merete Karlsborg Departments of Neurology and Radiology, Bispebjerg Hospital, Copenhagen University Hospital, Copenhagen, Denmark
,
Allan Bardow Section of Oral Medicine, Clinical Oral Physiology, Oral Pathology and Anatomy, School of Dentistry, Faculty of Health Sciences, University of Copenhagen, Copenhagen, Denmark
,
Joan Lykkeaa Section of Oral Medicine, Clinical Oral Physiology, Oral Pathology and Anatomy, School of Dentistry, Faculty of Health Sciences, University of Copenhagen, Copenhagen, Denmark
,
Flemming H. Nissen Departments of Neurology and Radiology, Bispebjerg Hospital, Copenhagen University Hospital, Copenhagen, Denmark
&
Merete Bakke Section of Oral Medicine, Clinical Oral Physiology, Oral Pathology and Anatomy, School of Dentistry, Faculty of Health Sciences, University of Copenhagen, Copenhagen, DenmarkCorrespondence[email protected]
Pages 151-157 | Received 25 Jun 2010, Accepted 20 Oct 2010, Published online: 03 Jan 2011

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Martin Checklin, Mary Etty-Leal, Tim A. Iseli, Nicholas Potter, Sally Fisher & Lauren Chapman. (2015) Saliva management options for difficult-to-wean people with tracheostomy following severe acquired brain injury (ABI): A review of the literature. Brain Injury 29:1, pages 1-10.
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Morten Gersel Stokholm, Carsten Bisgård & Ole Jakob Vilholm. (2013) Safety and administration of treatment with botulinum neurotoxin for sialorrhoea in ALS patients: Review of the literature and a proposal for tailored treatment. Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration 14:7-8, pages 516-520.
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Articles from other publishers (23)

Talyta Grippe & Robert Chen. (2023) Botulinum toxin in the management of parkinsonian disorders. Toxicon 232, pages 107209.
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Sara Baram & Merete Bakke. (2023) Oral sundhed og orofacial funktion ved Parkinsons sygdom. Aktuel Nordisk Odontologi 48:1, pages 6-17.
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Sherri Lynne Katz. 2023. Pulmonary Assessment and Management of Patients with Pediatric Neuromuscular Disease. Pulmonary Assessment and Management of Patients with Pediatric Neuromuscular Disease 91 110 .
Amy Hughes & Elton M. Lambert. (2022) Drooling and Aspiration of Saliva. Otolaryngologic Clinics of North America 55:6, pages 1181-1194.
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Merete Bakke. (2022) Botulinum Toxin, a Drug with Potential Interest for Dentists—An Introduction. Toxins 14:10, pages 667.
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Eleanor James, Cathy Ellis, Ruth Brassington, Sivakumar Sathasivam & Carolyn A Young. (2022) Treatment for sialorrhea (excessive saliva) in people with motor neuron disease/amyotrophic lateral sclerosis. Cochrane Database of Systematic Reviews 2022:5.
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Jessica Harbottle, Hannah Carlin, Thomas Payne-Doris, Hilary M I Tedd, Anthony de Soyza & Ben Messer. (2022) Developing an intrasalivary gland botox service for patients receiving long-term non-invasive ventilation at home: a single-centre experience. BMJ Open Respiratory Research 9:1, pages e001188.
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Raja Mehanna & Joseph Jankovic. 2022. Handbook of Neurotoxicity. Handbook of Neurotoxicity 1095 1143 .
Sara Baram, Merete Karlsborg, Esben Boeskov Øzhayat & Merete Bakke. (2021) Effect of orofacial physiotherapeutic and hygiene interventions on oral health–related quality of life in patients with Parkinson’s disease: A randomised controlled trial. Journal of Oral Rehabilitation 48:9, pages 1035-1043.
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Luis Solabre Valois, Vanilla (Hua) Shi, Paul Bishop, Bangfu Zhu, Yasuko Nakamura, Kevin A. Wilkinson & Jeremy M. Henley. (2021) Neurotrophic effects of Botulinum neurotoxin type A in hippocampal neurons involve activation of Rac1 by the non-catalytic heavy chain (HCC/A). IBRO Neuroscience Reports 10, pages 196-207.
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Raja Mehanna & Joseph Jankovic. 2021. Handbook of Neurotoxicity. Handbook of Neurotoxicity 1 48 .
Timothy D. Smile, Kristine Bauer-Nilsen & Chirag S. Shah. (2020) External-Beam Radiation Therapy for Treatment of Sialorrhea in Amyotrophic Lateral Sclerosis: A Case Report and Review of the Literature. Applied Radiation Oncology, pages 38-42.
Crossref
Merete BakkeBørge HedeMerete Karlsborg. (2020) Oral sundhed og orofacial funktion vedneurodegenerative sygdomme. Aktuel Nordisk Odontologi 45:1, pages 179-193.
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Juan Ruiz-Roca, Eduardo Pons-Fuster & Pia Lopez-Jornet. (2019) Effectiveness of the Botulinum Toxin for Treating Sialorrhea in Patients with Parkinson’s Disease: A Systematic Review. Journal of Clinical Medicine 8:3, pages 317.
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Mi Wang, Wael Saasouh, Thomas Botsford, Allen Keebler, Andrew Zura, Michael S. Benninger & Rafi Avitsian. (2018) Postoperative Stridor and Acute Respiratory Failure After Parkinson Disease Deep Brain Stimulator Placement: Case Report and Review of Literature. World Neurosurgery 111, pages 22-25.
Crossref
Merete Bakke, Allan Bardow & Eigild Møller. (2016) Savlen - et tværfagligt problem. Aktuel Nordisk Odontologi 41:1, pages 74-85.
Crossref
Martina Petracca, Arianna Guidubaldi, Lucia Ricciardi, Tàmara Ialongo, Alessandra Del Grande, Delia Mulas, Enrico Di Stasio & Anna Rita Bentivoglio. (2015) Botulinum Toxin A and B in sialorrhea: Long-term data and literature overview. Toxicon 107, pages 129-140.
Crossref
Mar?a T. G?mez-Caravaca, Mar?a T. C?ceres-Redondo, Ismael Huertas-Fern?ndez, Laura Vargas-Gonz?lez, F?tima Carrillo, Manuel Carballo & Pablo Mir. (2014) The use of botulinum toxin in the treatment of sialorrhea in parkinsonian disorders. Neurological Sciences 36:2, pages 275-279.
Crossref
E. Møller, D. Daugaard, O. Holm, K. Winge, A. Bardow, J. Lykkeaa, B. Belhage & M. Bakke. (2015) Repeated treatments of drooling with botulinum toxin B in neurology. Acta Neurologica Scandinavica 131:1, pages 51-57.
Crossref
Sarah Khan, Emerald Lin & Jonathan S. Kirschner. 2014. Atlas of Ultrasound Guided Musculoskeletal Injections. Atlas of Ultrasound Guided Musculoskeletal Injections 101 121 .
Raja Mehanna & Joseph Jankovic. 2014. Handbook of Neurotoxicity. Handbook of Neurotoxicity 553 590 .
J. Tiigimäe-Saar, E. Leibur, A. Kolk, I. Talvik & T. Tamme. (2012) Use of botulinum neurotoxin A in uncontrolled salivation in children with cerebral palsy: a pilot study. International Journal of Oral and Maxillofacial Surgery 41:12, pages 1540-1545.
Crossref
Merete Bakke, Allan Bardow & Eigild Møller. (2012) Severe Drooling and Treatment With Botulinum Toxin. Perspectives on Swallowing and Swallowing Disorders (Dysphagia) 21:1, pages 15-21.
Crossref

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