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Original Article

Organ Culture of the Mammalian Inner Ear

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Pages 303-312 | Received 13 May 1970, Published online: 08 Jul 2009

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Read on this site (11)

H. M. Sobkowicz, J. M. Loftus & S. M. Slapnick. (1993) Tissue Culture of the Organ of Corti: Part II. Acta Oto-Laryngologica 113:sup502, pages 20-36.
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T. R. Van De Water, V. Galinovic-Schwartz & R. J. Ruben. (1989) Determinants of Ganglion-receptor Cell Interaction during Development of the Inner Ear: A Heterochronic Ganglia Study. Acta Oto-Laryngologica 108:3-4, pages 227-237.
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Lars A. Lundman, Leif Holmquist & Dan Bagger-Sjöbäck. (1987) Round Window Membrane Permeability: An in Vitro Model. Acta Oto-Laryngologica 104:5-6, pages 472-480.
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Matti Anniko. (1979) Extracorporeal Preservation: Organ Culture of the Post-Natal Mammalian Inner Ear. Acta Oto-Laryngologica 88:1-6, pages 211-219.
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M. Anniko, T. R. Van de Water & H. Nordemar. (1978) Organ Culture of the 16th Gestation Day Mouse Labyrinth:A Model Suggestion for Pre- and Post-partum Development. Acta Oto-Laryngologica 86:1-6, pages 52-55.
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I. Friedmann, Gisele M. Hodges & P. N. Riddle. (1977) Organ Culture of the Avian and Mammalian Otocyst. Acta Oto-Laryngologica 83:1-6, pages 170-174.
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R. Van De Water & P. Hey Wood. (1976) The in vitro Development of Innervated Sensory Hair Cells of a Mammal. Acta Oto-Laryngologica 82:1-6, pages 337-342.
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T. Yamashita & K. H. Vosteen. (1975) Tissue Culture of the Organ of corti and the Isolated hair cells from the Newborn Guinea Pig. Acta Oto-Laryngologica 79:sup330, pages 77-90.
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. (1971) IX. Bibliography. Acta Oto-Laryngologica 71:sup285, pages 19-77.
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Articles from other publishers (73)

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Steven H. Green, Erin M. Bailey, Jonathan C. Kopelovich & Marlan R. Hansen. 2016. The Primary Auditory Neurons of the Mammalian Cochlea. The Primary Auditory Neurons of the Mammalian Cochlea 191 227 .
Michael Melnick & Tina Jaskoll. (2015) CMV-induced embryonic mouse organ of corti dysplasia: Network architecture of dysfunctional lateral inhibition. Birth Defects Research Part A: Clinical and Molecular Teratology 103:7, pages 573-582.
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Yves Brand, Michael Sung, Kwang Pak, Eduardo Chavez, Eric Wei, Vesna Radojevic, Daniel Bodmer & Allen F. Ryan. (2014) Neural Cell Adhesion Molecule NrCAM Is Expressed in the Mammalian Inner Ear and Modulates Spiral Ganglion Neurite Outgrowth in an In Vitro Alternate Choice Assay. Journal of Molecular Neuroscience 55:4, pages 836-844.
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Yves Brand, Michael Sung, Eduardo Chavez, Eric Wei, Kwang K. Pak, Gary D. Housley, Daniel Bodmer & Allen F. Ryan. (2013) Neural Cell Adhesion Molecule L1 Modulates Type I But Not Type II Inner Ear Spiral Ganglion Neurite Outgrowth in an In Vitro Alternate Choice Assay. Journal of Molecular Neuroscience 51:3, pages 663-670.
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Sara Euteneuer, Kuo H. Yang, Eduardo Chavez, Anke Leichtle, Gabriele Loers, Adel Olshansky, Kwang Pak, Melitta Schachner & Allen F. Ryan. (2013) Glial cell line-derived neurotrophic factor (GDNF) induces neuritogenesis in the cochlear spiral ganglion via neural cell adhesion molecule (NCAM). Molecular and Cellular Neuroscience 54, pages 30-43.
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Michael Melnick & Tina Jaskoll. (2012) An in vitro mouse model of congenital cytomegalovirus‐induced pathogenesis of the inner ear cochlea. Birth Defects Research Part A: Clinical and Molecular Teratology 97:2, pages 69-78.
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Fabio Mammano. (2013) ATP-dependent intercellular Ca2+ signaling in the developing cochlea: Facts, fantasies and perspectives. Seminars in Cell & Developmental Biology 24:1, pages 31-39.
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Robert J. Marano & Sharon L. Redmond. (2011) In vitro cultured primary cells from a human utricle explant possesses hair cell like characteristics. Journal of Molecular Histology 42:4, pages 365-370.
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S. Hansen, R. Mlynski, S. Volkenstein, T. Stark, M. Schwaab, S. Dazert & D. Brors. (2009) Wachstumsanalyse von Spiralganglienexplantaten auf Kochleaimplantat-Elektroden und deren MaterialkomponentenGrowth behavior of spiral ganglion explants on cochlear implant electrodes and their materials. HNO 57:4, pages 358-363.
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Hartmut Hahn, Marcus Müller & Hubert Löwenheim. (2008) Whole organ culture of the postnatal sensory inner ear in simulated microgravity. Journal of Neuroscience Methods 171:1, pages 60-71.
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Amaretta R. Evans, Sara Euteneuer, Eduardo Chavez, Lina M. Mullen, Elliot E. Hui, Sangeeta N. Bhatia & Allen F. Ryan. (2007) Laminin and fibronectin modulate inner ear spiral ganglion neurite outgrowth in anin vitro alternate choice assay. Developmental Neurobiology 67:13, pages 1721-1730.
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Robert Mlynski, Stefan Volkenstein, Stefan Hansen, Dominik Brors, Joerg Ebmeyer & Stefan Dazert. (2009) Interaction of Cochlear Nucleus Explants With Semiconductor Materials. The Laryngoscope 117:7, pages 1216-1222.
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Tatsunori Sakamoto, Juichi Ito & Raj K. Ladher. (2007) Hair cell differentiation becomes tissue specific by E9.5 in mouse inner ear. NeuroReport 18:9, pages 841-844.
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A. Albinger-Hegyi, I. Hegyi, I. Nagy, M. Bodmer, S. Schmid & D. Bodmer. (2006) Alteration of activator protein 1 DNA binding activity in gentamicin-induced hair cell degeneration. Neuroscience 137:3, pages 971-980.
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Ivana Nagy, Arianne Monge, Andrea Albinger-Hegyi, Stephan Schmid & Daniel Bodmer. (2005) NF-κB is Required for Survival of Immature Auditory Hair Cells In Vitro. Journal of the Association for Research in Otolaryngology 6:3, pages 260-268.
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Ivana Nagy, Morana Bodmer, Dominik Brors & Daniel Bodmer. (2004) Early gene expression in the organ of Corti exposed to gentamicin. Hearing Research 195:1-2, pages 1-8.
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Dominik Brors, Daniel Bodmer, Kwang Pak, Christoph Aletsee, Maria Schäfers, Stefan Dazert & Allen F. Ryan. (2003) EphA4 provides repulsive signals to developing cochlear ganglion neurites mediated through ephrin‐B2 and ‐B3. Journal of Comparative Neurology 462:1, pages 90-100.
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Malin Hulander, Amy E. Kiernan, Sandra Rodrigo Blomqvist, Peter Carlsson, Emma-Johanna Samuelsson, Bengt R. Johansson, Karen P. Steel & Sven Enerbäck. (2003) Lack of pendrin expression leads to deafness and expansion of the endolymphatic compartment in inner ears of Foxi1 null mutant mice . Development 130:9, pages 2013-2025.
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Christoph Aletsee, Dominik Brors, Robert Mlynski, Allen F. Ryan & Stefan Dazert. (2009) Branching of Spiral Ganglion Neurites Is Induced by Focal Application of Fibroblast Growth Factor‐1. The Laryngoscope 113:5, pages 791-796.
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Daniel Bodmer, Dominik Brors, Kwang Pak, Morana Bodmer & Allen F. Ryan. (2009) Gentamicin‐Induced Hair Cell Death Is Not Dependent on the Apoptosis Receptor Fas. The Laryngoscope 113:3, pages 452-455.
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David Z.Z He, Shuping Jia & Feng Feng. (2003) Thyroid hormone is not necessary for the development of outer hair cell electromotility. Hearing Research 175:1-2, pages 183-189.
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Daniel Bodmer, Bertrand Gloddek, Allen F. Ryan, Jochen Huverstuhl & Dominik Brors. (2009) Inhibition of the c‐Jun N‐Terminal Kinase Signaling Pathway Influences Neurite Outgrowth of Spiral Ganglion Neurons In Vitro. The Laryngoscope 112:11, pages 2057-2061.
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Daniel Bodmer, Dominik Brors, Kwang Pak, Bertrand Gloddek & Allen F Ryan. (2002) Rescue of auditory hair cells from aminoglycoside toxicity by Clostridium difficile toxin B, an inhibitor of the small GTPases Rho/Rac/Cdc42. Hearing Research 172:1-2, pages 81-86.
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Daniel Bodmer, Dominik Brors, Kwang Pak, Elizabeth M Keithley, Lina Mullen, Allen F Ryan & Bertrand Gloddek. (2002) Inflammatory signals increase Fas ligand expression by inner ear cells. Journal of Neuroimmunology 129:1-2, pages 10-17.
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Dominik Brors, Christoph Aletsee, Konrad Schwager, Robert Mlynski, Stefan Hansen, Maria Schäfers, Allen F. Ryan & Stefan Dazert. (2002) Interaction of spiral ganglion neuron processes with alloplastic materials in vitro. Hearing Research 167:1-2, pages 110-121.
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Christoph Aletsee, Dominik Brors, Sean Palacios, Kwang Pak, Lina Mullen, Stefan Dazert & Allen F Ryan. (2002) The effects of laminin-1 on spiral ganglion neurons are dependent on the MEK/ERK signaling pathway and are partially independent of Ras. Hearing Research 164:1-2, pages 1-11.
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Nicolas Daudet, Chantal Ripoll & Marc Lenoir. (2001) Transforming growth factor‐α‐induced cellular changes in organotypic cultures of juvenile, amikacin‐treated rat organ of corti. Journal of Comparative Neurology 442:1, pages 6-22.
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David Z.Z. He, Jing Zheng & Peter Dallos. (2001) Development of acetylcholine receptors in cultured outer hair cells. Hearing Research 162:1-2, pages 113-125.
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S Dazert, A Baird & A.F Ryan. (1998) Receptor-targeted delivery of an intracellular toxin to outer hair cells by fibroblast growth factor. Hearing Research 115:1-2, pages 143-148.
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Thomas Van De Water & R. J. Ruben. (2016) Growth of the Inner Ear in Organ Culture. Annals of Otology, Rhinology & Laryngology 83:5_suppl, pages 1-16.
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Thomas Van De Water & Robert J. Ruben. (2016) Quantification of the “In Vitro” Development of the Mouse Embryo Inner Ear. Annals of Otology, Rhinology & Laryngology 82:1, pages 19-21.
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Thomas R. Van De Water, P. Heywood & Robert J. Ruben. (2016) Development of Sensory Structures in Organ Cultures of the Twelfth and Thirteenth Gestation Day Mouse Embryo Inner Ears. Annals of Otology, Rhinology & Laryngology 82:1, pages 1-18.
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