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Original Article

The Effect of Cerebrospinal Fluid Pressure on Perilymphatic Flow in the Opened Cochlea

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Pages 198-202 | Received 06 Nov 1978, Published online: 08 Jul 2009

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Read on this site (7)

A. N. Salt, N. Inamura, R. Thalmann & A. R. Vora. (1991) Evaluation of Procedures to Reduce Fluid Flow in the Fistulized Guinea-pig Cochlea. Acta Oto-Laryngologica 111:5, pages 899-907.
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G. M. McLaren, H. A. Dengerink, P. A. Hellstrom & J. W. Wright. (1991) Effects of Perilymph Volume Adjustments on Cochlear Blood Flow in the Guinea Pig. Acta Oto-Laryngologica 111:1, pages 94-100.
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R. J. Marchbanks & A. Reid. (1990) Cochlear and cerebrospinal fluid pressure: Their inter-relationship and control mechanisms. British Journal of Audiology 24:3, pages 179-187.
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Ruediger Thalmann. (1985) Gradients of Organic Substances between Fluid Compartments of the Cochlea. Acta Oto-Laryngologica 99:3-4, pages 469-477.
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M. H. Brac, P. Lycett And & J. A. McClure. (1984) Effect of High Perilymphatic Potassium on Brainstem Evoked Response Audiometric Thresholds. Acta Oto-Laryngologica 97:3-4, pages 267-272.
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S. K. Juhn & L. P. Rybak. (1981) Labyrinthine Barriers and Cochlear Homeostasis. Acta Oto-Laryngologica 91:1-6, pages 529-534.
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Articles from other publishers (26)

Céline Jaudoin, Florence Agnely, Yann Nguyen, Evelyne Ferrary & Amélie Bochot. (2021) Nanocarriers for drug delivery to the inner ear: Physicochemical key parameters, biodistribution, safety and efficacy. International Journal of Pharmaceutics 592, pages 120038.
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Vishal Raghu, Yugandhar Ramakrishna, Robert F. Burkard & Soroush G. Sadeghi. (2020) A novel intracochlear injection method for rapid drug delivery to vestibular end organs. Journal of Neuroscience Methods 341, pages 108689.
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Alec N. Salt & Keiko Hirose. (2018) Communication pathways to and from the inner ear and their contributions to drug delivery. Hearing Research 362, pages 25-37.
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J.T. Lichtenhan, J. Hartsock, J.R. Dornhoffer, K.M. Donovan & A.N. Salt. (2016) Drug delivery into the cochlear apex: Improved control to sequentially affect finely spaced regions along the entire length of the cochlear spiral. Journal of Neuroscience Methods 273, pages 201-209.
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Stefan K. Plontke, Jared J. Hartsock, Ruth M. Gill & Alec N. Salt. (2016) Intracochlear Drug Injections through the Round Window Membrane: Measures to Improve Drug Retention. Audiology and Neurotology 21:2, pages 72-79.
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Gang Gao, Ya Liu, Chang-Hua Zhou, Ping Jiang & Jian-Jun Sun. (2015) Solid Lipid Nanoparticles Loaded with Edaravone for Inner Ear Protection After Noise Exposure. Chinese Medical Journal 128:2, pages 203-209.
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Keiko Hirose, Jared J. Hartsock, Shane Johnson, Peter Santi & Alec N. Salt. (2014) Systemic Lipopolysaccharide Compromises the Blood-Labyrinth Barrier and Increases Entry of Serum Fluorescein into the Perilymph. Journal of the Association for Research in Otolaryngology 15:5, pages 707-719.
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J. T. Lichtenhan, J. J. Hartsock, R. M. Gill, J. J. GuinanJr.Jr. & A. N. Salt. (2014) The Auditory Nerve Overlapped Waveform (ANOW) Originates in the Cochlear Apex. Journal of the Association for Research in Otolaryngology 15:3, pages 395-411.
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E. B. King, A. N. Salt, H. T. Eastwood & S. J. O’Leary. (2011) Direct Entry of Gadolinium into the Vestibule Following Intratympanic Applications in Guinea Pigs and the Influence of Cochlear Implantation. Journal of the Association for Research in Otolaryngology 12:6, pages 741-751.
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M. Praetorius. 2010. Hören und Gleichgewicht. Hören und Gleichgewicht 25 32 .
Erin E. Leary Swan, Mark J. Mescher, William F. Sewell, Sarah L. Tao & Jeffrey T. Borenstein. (2008) Inner ear drug delivery for auditory applications. Advanced Drug Delivery Reviews 60:15, pages 1583-1599.
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Robert Mynatt, Shane A. Hale, Ruth M. Gill, Stefan K. Plontke & Alec N. Salt. (2006) Demonstration of a Longitudinal Concentration Gradient Along Scala Tympani by Sequential Sampling of Perilymph from the Cochlear Apex. Journal of the Association for Research in Otolaryngology 7:2, pages 182-193.
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Alec N. Salt, Shane A. Hale & Stefan K.R. Plonkte. (2006) Perilymph sampling from the cochlear apex: A reliable method to obtain higher purity perilymph samples from scala tympani. Journal of Neuroscience Methods 153:1, pages 121-129.
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Zhiqiang Chen, Sharon G. Kujawa, Michael J. McKenna, Jason O. Fiering, Mark J. Mescher, Jeffrey T. Borenstein, Erin E. Leary Swan & William F. Sewell. (2005) Inner ear drug delivery via a reciprocating perfusion system in the guinea pig. Journal of Controlled Release 110:1, pages 1-19.
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Alec N. Salt, Christian Kellner & Shane Hale. (2003) Contamination of perilymph sampled from the basal cochlear turn with cerebrospinal fluid. Hearing Research 182:1-2, pages 24-33.
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Alec N Salt & Yilong Ma. (2001) Quantification of solute entry into cochlear perilymph through the round window membrane. Hearing Research 154:1-2, pages 88-97.
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A.J. Winter, S.D. Comis, M.P. Osborne, T.L. Hayward, J. Stephen & M.J. Tarlow. (1998) Ototoxicity resulting from intracochlear perfusion of Streptococcus pneumoniae in the guinea pig is modified by cefotaxime or amoxycillin pretreatment. Journal of Infection 36:1, pages 73-77.
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Sanmg W. Yeo, Stefan Gottschlich, Jeffrey P. Harrris & Elizabeth M. Keithley. (2009) Antigen Diffusion from the perilymphatic space of the cochlea. The Laryngoscope 105:6, pages 623-628.
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Cecilia A. Lopez, Elizabeth S. Olson, Joe C. Adams, Kewa Mou, David T. Denhardt & Robin L. Davis. (1995) Osteopontin expression detected in adult cochleæ and inner ear fluids. Hearing Research 85:1-2, pages 210-222.
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K. Hisashi, S. Komune, T. Kimitsuki, T. Nakagawa & T. Uemura. (1994) Potassium circulation in the perilymph of guinea pig cochlea. European Archives of Oto-Rhino-Laryngology 251:S1, pages S48-S52.
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Alec N. Salt & Kenji Ohyama. (2016) Accumulation of Potassium in Scala Vestibuli Perilymph of the Mammalian Cochlea. Annals of Otology, Rhinology & Laryngology 102:1, pages 64-70.
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K.C. Horner. (1991) Old theme and new reflections: Hearing impairment associated with endolymphatic hydrops. Hearing Research 52:1, pages 147-156.
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Akira Kara, Alec N. Salt & Ruediger Thalmann. (1989) Perilymph composition in scala tympani of the cochlea: Influence of cerebrospinal fluid. Hearing Research 42:2-3, pages 265-271.
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Kenji Ohyama, Alec N. Salt & Ruediger Thalmann. (1988) Volume flow rate of perilymph in the guinea-pig cochlea. Hearing Research 35:2-3, pages 119-129.
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E. Lehnhardt. 1984. Verhandlungsbericht 1984 der Deutschen Gesellschaft für Hals- Nasen- Ohren-Heilkunde, Kopf- und Hals-Chirurgie. Verhandlungsbericht 1984 der Deutschen Gesellschaft für Hals- Nasen- Ohren-Heilkunde, Kopf- und Hals-Chirurgie 58 218 .
R. Thalmann, T. H. Comegys & I. Thalmann. (2009) Amino acid profiles in inner ear fluids and cerebrospinal fluid. The Laryngoscope 92:3, pages 321-328.
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