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Original Article

Effects of Hypothyroidism on the Structural Development of the Organ of Corti in the Rat

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Pages 469-480 | Received 19 Aug 1980, Published online: 08 Jul 2009

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M. François, P. Bonfils, J. Leger, P. Avan, P. Czernichow & P. Narcy. (1993) Audiological Assessment of Eleven Congenital Hypothyroid Infants Before and After Treatment. Acta Oto-Laryngologica 113:1, pages 39-42.
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Alain Uziel. (1986) Periods of Sensitivity to Thyroid Hormone during the Development of the Organ of Corti. Acta Oto-Laryngologica 101:sup429, pages 23-27.
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Alain Uziel. (1985) Non-genetic Factors Affecting Hearing Development. Acta Oto-Laryngologica 99:sup421, pages 57-61.
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F. Debruyne, M. Vanderschueren-Lodeweyckx & P. Bastijns. (1983) Hearing in Congenital Hypothyroidism. Audiology 22:4, pages 404-409.
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Articles from other publishers (78)

Jun Tan, Xueyan Wang, Yue Li, Qiang Song & Jun Yang. (2023) Impaired tectorial membrane and ribbon synapse maturation in the cochlea of mice with congenital hypothyroidism. Biochemical and Biophysical Research Communications 655, pages 68-74.
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Xue Bai, Kai Xu, Le Xie, Yue Qiu, Sen Chen & Yu Sun. (2023) The Dual Roles of Triiodothyronine in Regulating the Morphology of Hair Cells and Supporting Cells during Critical Periods of Mouse Cochlear Development. International Journal of Molecular Sciences 24:5, pages 4559.
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Jianyong Chen, Dekun Gao, Lianhua Sun & Jun Yang. (2022) Kölliker’s organ-supporting cells and cochlear auditory development. Frontiers in Molecular Neuroscience 15.
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Michael Ebeid, Kathy Barnas, Hongji Zhang, Amal Yaghmour, Gabriele Noreikaite & Bryan C. Bjork. (2022) PRDM16 expression and function in mammalian cochlear development . Developmental Dynamics 251:10, pages 1666-1683.
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Caio Leônidas Oliveira Andrade, Crésio de Aragão Dantas Alves & Helton Estrela Ramos. (2021) Congenital Hypothyroidism and the Deleterious Effects on Auditory Function and Language Skills: A Narrative Review. Frontiers in Endocrinology 12.
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Mohammad Reza Afarinesh, Faezeh Shafiei, Mansoureh Sabzalizadeh, Tahereh Haghpanah, Mahdieh Taheri, Shahrnaz Parsania, Fatemeh Golshan & Vahid Sheibani. (2020) Effect of mild and chronic neonatal hypothyroidism on sensory information processing in a rodent model: A behavioral and electrophysiological study. Brain Research Bulletin 155, pages 29-36.
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Caio Leônidas Oliveira de Andrade, Gabriela Carvalho Machado, Luciene da Cruz Fernandes, Jamile Morais de Albuquerque, Luciana Lyra Casais-e-Silva, Helton Estrela Ramos & Crésio de Aragão Dantas Alves. (2017) Mechanisms involved in hearing disorders of thyroid ontogeny: a literature review. Archives of Endocrinology and Metabolism 61:5, pages 501-505.
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Hiromi Wada. (2017) Acoustic alterations of ultrasonic vocalization in rat pups induced by perinatal hypothyroidism. NeuroToxicology 59, pages 175-182.
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David S. Sharlin. 2016. Thyroid Hormone Disruption and Neurodevelopment. Thyroid Hormone Disruption and Neurodevelopment 133 150 .
Hellmuth Lilienthal, Merja Korkalainen, Patrik L. Andersson & Matti Viluksela. (2015) Developmental exposure to purity-controlled polychlorinated biphenyl congeners (PCB74 and PCB95) in rats: Effects on brainstem auditory evoked potentials and catalepsy. Toxicology 327, pages 22-31.
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David S. Sharlin. 2015. Environmental Factors in Neurodevelopmental and Neurodegenerative Disorders. Environmental Factors in Neurodevelopmental and Neurodegenerative Disorders 167 192 .
Carl L.Faingold, Manish Raisinghani & Prosper N'Gouemo. 2014. Neuronal Networks in Brain Function, CNS Disorders, and Therapeutics. Neuronal Networks in Brain Function, CNS Disorders, and Therapeutics 349 373 .
Alida Melse-Boonstra & Ian Mackenzie. (2013) Iodine deficiency, thyroid function and hearing deficit: a review. Nutrition Research Reviews 26:2, pages 110-117.
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Vassilis Psaltakos, Dimitrios G. Balatsouras, Ioannis Sengas, Eleftherios Ferekidis, Maria Riga & Stavros G. Korres. (2012) Cochlear dysfunction in patients with acute hypothyroidism. European Archives of Oto-Rhino-Laryngology 270:11, pages 2839-2848.
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Hiromi Wada, Shoko Yumoto & Hiroyuki Iso. (2013) Irreversible damage to auditory system functions caused by perinatal hypothyroidism in rats. Neurotoxicology and Teratology 37, pages 18-22.
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Emily A. Cordas, Lily Ng, Arturo Hernandez, Masahiro Kaneshige, Sheue-Yann Cheng & Douglas Forrest. (2012) Thyroid Hormone Receptors Control Developmental Maturation of the Middle Ear and the Size of the Ossicular Bones. Endocrinology 153:3, pages 1548-1560.
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Robert C. Froemke & Bianca J. Jones. (2011) Development of auditory cortical synaptic receptive fields. Neuroscience & Biobehavioral Reviews 35:10, pages 2105-2113.
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Claus-Peter Richter, Adrian Münscher, Danielle Santana Machado, Fredric E. Wondisford & Tania M. Ortiga-Carvalho. (2011) Complete Activation of Thyroid Hormone Receptor β by T<sub>3</sub> is Essential for Normal Cochlear Function and Morphology in Mice. Cellular Physiology and Biochemistry 28:5, pages 997-1008.
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Philine WangemannHyoung-Mi KimSara BillingsKazuhiro Nakaya, Xiangming LiRuchira SinghDavid S. Sharlin, Douglas Forrest, Daniel C. MarcusPeying Fong. (2009) Developmental delays consistent with cochlear hypothyroidism contribute to failure to develop hearing in mice lacking Slc26a4 /pendrin expression . American Journal of Physiology-Renal Physiology 297:5, pages F1435-F1447.
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Brian E. Powers, Emily Poon, Helen J.K. Sable & Susan L. Schantz. (2009) Developmental Exposure to PCBs, MeHg, or Both: Long-Term Effects on Auditory Function. Environmental Health Perspectives 117:7, pages 1101-1107.
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Mark D. Miller, Kevin M. Crofton, Deborah C. Rice & R. Thomas Zoeller. (2009) Thyroid-Disrupting Chemicals: Interpreting Upstream Biomarkers of Adverse Outcomes. Environmental Health Perspectives 117:7, pages 1033-1041.
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Lei Song, JoAnn McGee & Edward J. Walsh. (2008) The Influence of Thyroid Hormone Deficiency on the Development of Cochlear Nonlinearities. Journal of the Association for Research in Otolaryngology 9:4, pages 464-476.
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Karolina Banghova, Eva Al Taji, Ondrej Cinek, Dana Novotna, Radka Pourova, Jirina Zapletalova, Olga Hnikova & Jan Lebl. (2007) Pendred syndrome among patients with congenital hypothyroidism detected by neonatalscreening: identification of two novel PDS/SLC26A4 mutations. European Journal of Pediatrics 167:7, pages 777-783.
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Kevin M. Crofton. (2008) Thyroid disrupting chemicals: mechanisms and mixtures. International Journal of Andrology 31:2, pages 209-223.
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Michel Guipponi, Justin Tan, Ping Z.F. Cannon, Lauren Donley, Pauline Crewther, Maria Clarke, Qingyu Wu, Robert K. Shepherd & Hamish S. Scott. (2007) Mice Deficient for the Type II Transmembrane Serine Protease, TMPRSS1/hepsin, Exhibit Profound Hearing Loss. The American Journal of Pathology 171:2, pages 608-616.
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I. Jill Karolyi, Gary A. Dootz, Karin Halsey, Lisa Beyer, Frank J. Probst, Kenneth R. Johnson, Albert F. Parlow, Yehoash Raphael, David F. Dolan & Sally A. Camper. (2007) Dietary thyroid hormone replacement ameliorates hearing deficits in hypothyroid mice. Mammalian Genome 18:8, pages 596-608.
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Gaston Sendin, Anna V. Bulankina, Dietmar Riedel & Tobias Moser. (2007) Maturation of Ribbon Synapses in Hair Cells Is Driven by Thyroid Hormone. The Journal of Neuroscience 27:12, pages 3163-3173.
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Lei Song, Jo Ann McGee & Edward J. Walsh. (2006) Consequences of combined maternal, fetal and persistent postnatal hypothyroidism on the development of auditory function in Tshr mutant mice. Brain Research 1101:1, pages 59-72.
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Matthew W. Kelley. (2006) Hair cell development: Commitment through differentiation. Brain Research 1091:1, pages 172-185.
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K. M. Crofton. (2004) Developmental Disruption of Thyroid Hormone: Correlations with Hearing Dysfunction in Rats. Risk Analysis 24:6, pages 1665-1671.
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Lily Ng, Richard J. Goodyear, Chad A. Woods, Mark J. Schneider, Edward Diamond, Guy P. Richardson, Matthew W. Kelley, Donald L. St. Germain, Valerie Anne Galton & Douglas Forrest. (2004) Hearing loss and retarded cochlear development in mice lacking type 2 iodothyronine deiodinase. Proceedings of the National Academy of Sciences 101:10, pages 3474-3479.
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Joaquin Rueda, Raquel Cantos & David J. Lim. (2003) Distribution of glycoconjugates during cochlea development in mice: Light microscopic lectin study. The Anatomical Record 274A:2, pages 923-933.
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Marta Parazzini, Paolo Ravazzani, Stefania Medaglini, Giovanna Weber, Carla Fornara, Gabriella Tognola, Maria Cristina Vigone, Carlo Bianchi, Giancarlo Comi, Giuseppe Chiumello & Ferdinando Grandori. (2002) Click-evoked otoacoustic emissions recorded from untreated congenital hypothyroid newborns. Hearing Research 166:1-2, pages 136-142.
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Alfons Rüsch, Lily Ng, Richard Goodyear, Dominik Oliver, Igor Lisoukov, Björn Vennström, Guy Richardson, Matthew W. Kelley & Douglas Forrest. (2001) Retardation of Cochlear Maturation and Impaired Hair Cell Function Caused by Deletion of All Known Thyroid Hormone Receptors. The Journal of Neuroscience 21:24, pages 9792-9800.
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David W Herr, Jaimie E Graff, Ethel C Derr-Yellin, Kevin M Crofton & Prasada R.S Kodavanti. (2001) Flash-, somatosensory-, and peripheral nerve-evoked potentials in rats perinatally exposed to Aroclor 1254. Neurotoxicology and Teratology 23:6, pages 591-601.
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Marlies Knipper, Guy Richardson, Andreas Mack, Markus Müller, Richard Goodyear, Annette Limberger, Karin Rohbock, Iris Köpschall, Hans-Peter Zenner & Ulrike Zimmermann. (2001) Thyroid Hormone-deficient Period Prior to the Onset of Hearing Is Associated with Reduced Levels of β-Tectorin Protein in the Tectorial Membrane. Journal of Biological Chemistry 276:42, pages 39046-39052.
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Lily Ng, Pablo E. Pedraza, Jonathan S. Faris, Björn Vennström, Tom Curran, Gabriella Morreale de Escobar & Douglas Forrest. (2001) Audiogenic seizure susceptibility in thyroid hormone receptor β-deficient mice. Neuroreport 12:11, pages 2359-2362.
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