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Original Article

A Method for Evaluating the Effect of Pharmacological Substances on Mucociliary Activity in Vivo

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Pages 151-159 | Received 02 Mar 1981, Published online: 08 Jul 2009

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Read on this site (10)

Anders Cervin, Sven Lindberg, Ulf Mercke & Rolf Uddman. (1992) Neuropeptide Y in the Rabbit Maxillary Sinus Modulates Cholinergic Acceleration of Mucociliary Activity. Acta Oto-Laryngologica 112:5, pages 872-881.
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Anders Cervin, Sven Lindberg & Ulf Mercke. (1991) The Effect of Neuropeptide Y on Mucociliary Activity in the Rabbit Maxillary Sinus. Acta Oto-Laryngologica 111:5, pages 960-966.
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Sven Lindberg & HÅKan Olsson. (1991) Tissue Kallikrein Stimulates Mucociliary Activity in the Rabbit Maxillary Sinus. Acta Oto-Laryngologica 111:6, pages 1126-1132.
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Jan Dolata, Sven Lindberg & Ulf Mercke. (1990) The influence of leukotrienes and platelet activating factor on mucociliary activity in the rabbit maxillary sinus. Acta Oto-Laryngologica 109:1-2, pages 149-154.
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Jan Dolata, Sven Lindberg & Ulf Mercke. (1989) Cholinergic and C-Fibre Mediated Mechanisms in the Stimulation of Mucociliary Activity Induced by Prostaglandins and Histamine. Acta Oto-Laryngologica 108:5-6, pages 456-463.
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Jan Dolata, Sven Lindberg & Ulf Mercke. (1989) The Effects of Prostaglandins E1 E2 and F2α on Mucociliary Activity in the Rabbit Maxillary Sinus. Acta Oto-Laryngologica 108:3-4, pages 290-297.
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Anders Cervin, Mats Bende, Sven Lindberg, Ulf Mercke & Peter Olsson. (1988) Relations between Blood Flow and Mucociliary Activity in the Rabbit Maxillary Sinus. Acta Oto-Laryngologica 105:3-4, pages 350-356.
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Sven Lindberg, Jan Dolata & Ulf Mercke. (1987) Nasal Exposure to Airway Irritants Triggers a Mucociliary Defence Reflex in the Rabbit Maxillary Sinus. Acta Oto-Laryngologica 104:5-6, pages 552-560.
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Sven Lindberg & Ulf Mercke. (1986) Antidromic Nerve Stimulation Accelerates Mucociliary Activity in Rabbit Maxillary Sinus. Acta Oto-Laryngologica 101:5-6, pages 484-493.
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Sven Lindberg & Ulf Mercke. (1986) Bradykinin Accelerates Mucociliary Activity in Rabbit Maxillary Sinus. Acta Oto-Laryngologica 101:1-2, pages 114-121.
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Chuan Pang, Fengwei An, Shiming Yang, Ning Yu, Daishi Chen & Lei Chen. (2020) In vivo and in vitro observation of nasal ciliary motion in a guinea pig model . Experimental Biology and Medicine 245:12, pages 1039-1048.
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Kristy D. Bruse. 2016. Drug Discovery and Evaluation: Pharmacological Assays. Drug Discovery and Evaluation: Pharmacological Assays 1011 1028 .
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Kristy D. Bruse. 2014. Drug Discovery and Evaluation: Pharmacological Assays. Drug Discovery and Evaluation: Pharmacological Assays 1 19 .
Yuchi Wang, Lid B. Wong & Hua Mao. (2010) Creation of a long-lifespan ciliated epithelial tissue structure using a 3D collagen scaffold. Biomaterials 31:5, pages 848-853.
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Ga Young ParkHyo Yeol KimJin-Young MinHun-Jong DhongSeung-Kyu Chung. (2010) Endodontic Treatment: A Significant Risk Factor for the Development of Maxillary Fungal Ball. Clinical and Experimental Otorhinolaryngology 3:3, pages 136.
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Hans Gerhard Vogel. 2008. Drug Discovery and Evaluation. Drug Discovery and Evaluation 511 564 .
Jonathan Rutland, Lucy Morgan & Robb de Iongh. 2004. Therapy for Mucus-Clearance Disorders. Therapy for Mucus-Clearance Disorders 225 306 .
C. H. J. Hauman, N. P. Chandler & D. C. Tong. (2002) Endodontic implications of the maxillary sinus: a review. International Endodontic Journal 35:2, pages 127-141.
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H. Gerhard Vogel, Wolfgang H. Vogel, Bernward A. Schölkens, Jürgen Sandow, Günter Müller & Wolfgang F. Vogel. 2002. Drug Discovery and Evaluation. Drug Discovery and Evaluation 351 383 .
Emmeline Marttin, Nicolaas G.M Schipper, J.Coos Verhoef & Frans W.H.M Merkus. (1998) Nasal mucociliary clearance as a factor in nasal drug delivery. Advanced Drug Delivery Reviews 29:1-2, pages 13-38.
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H. Gerhard Vogel & Wolfgang H. Vogel. 1997. Drug Discovery and Evaluation. Drug Discovery and Evaluation 183 203 .
Sven Lindberg, Thomas Runer, Anders Cervin & Lars Thomasson. (2016) Recordings of Mucociliary Activity in Vivo: Benefit of Fast Fourier Transformation of the Photoelectric Signal. Annals of Otology, Rhinology & Laryngology 105:9, pages 734-745.
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Thomas Runer, Sven Lindberg, Ulf Mercke & Peter Olsson. (2018) Effects of Substance P and Methacholine on Mucosal Blood Flow in the Upper Airways. American Journal of Rhinology 9:6, pages 335-348.
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Sven Lindberg, Rauf Khan & Thomas Runer. (1995) The effects of formoterol, a long-acting β2-adrenoceptor agonist, on mucociliary activity. European Journal of Pharmacology 285:3, pages 275-280.
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Anders Cervin, Sven Lindberg & Ulf Mercke. (2016) Effects of halothane on mucociliary activity in vivo. Otolaryngology–Head and Neck Surgery 112:6, pages 714-722.
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Gerald Krennmair & Franz Lenglinger. (1995) Maxillary sinus aspergillosis. Journal of Oral and Maxillofacial Surgery 53:6, pages 657-663.
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Anders Cervin, Sven Lindberg, Jan Dolata & Ulf Mercke. (2016) Cyclic Adenosine Monophosphate Stimulation of Mucociliary Activity in the Upper Airways in Vivo. Annals of Otology, Rhinology & Laryngology 104:5, pages 388-393.
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Sven Lindberg & Thomas Runer. (2016) Method for in Vivo Measurement of Mucociliary Activity in the Human Nose. Annals of Otology, Rhinology & Laryngology 103:7, pages 558-566.
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Finn R. Amble, Sven O. H. Lindberg, Thomas V. McCaffrey & Thomas Runer. (2016) Second place — resident basic science award 1993: Mucociliary function and endothelins 1, 2, and 3. Otolaryngology–Head and Neck Surgery 109:4, pages 634-645.
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Louis A. Gatto. (1993) Cholinergic and adrenergic stimulation of mucociliary trasport in the rat trachea. Respiration Physiology 92:2, pages 209-217.
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Sven Lindberg & Jan Dolata. (1993) NK1 receptors mediate the increase in mucociliary activity produced by tachykinins. European Journal of Pharmacology 231:3, pages 375-380.
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Anders Cervin. (1992) Neuropeptide Y 16–36 inhibits mucociliary activity but does not affect blood flow in the rabbit maxillary sinus in vivo. Regulatory Peptides 39:2-3, pages 237-246.
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A. CERVIN, S. LINDBERG & U. MERCKE. (2008) Sympathetic nerve stimulation influences mucociliary activity in the rabbit maxillary sinus. Acta Physiologica Scandinavica 143:4, pages 405-412.
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Sven Lindberg & Rolf Uddman. (2018) The Rabbit Maxillary Sinus: A Review of the Effects of Innervation on Mucociliary Activity. American Journal of Rhinology 4:6, pages 225-233.
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Jan Dolata, Sven Lindberg & Ulf Mercke. (2016) Histamine Stimulation of Mucociliary Activity in the Rabbit Maxillary Sinus. Annals of Otology, Rhinology & Laryngology 99:8, pages 666-671.
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Jan Dolata, Sven Lindberg & Ulf Mercke. (2018) Stimulation of Mucociliary Activity by Substance P and Capsaicin is Not Mediated by Histamine. American Journal of Rhinology 4:4, pages 141-144.
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Sven Lindberg, Jan Dolata & Ulf Mercke. (1990) Mucociliary activity and the diving reflex. American Journal of Otolaryngology 11:3, pages 182-187.
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H. Riechelmann, W. Mann & J. Maurer. (1990) The influence of Ca2+ antagonists on the ciliary activity of the guinea pig trachea. European Archives of Oto-Rhino-Laryngology 248:1, pages 35-39.
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Louis A. Gatto. (2005) Cell distribution in tracheal surface epithelium and the effects of long‐term pilocarpine and atropine administration. The Anatomical Record 225:2, pages 133-138.
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K Svartengren, L G Wiman, P Thyberg & R Rigler. (1989) Laser light scattering spectroscopy: a new method to measure tracheobronchial mucociliary activity.. Thorax 44:7, pages 539-547.
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T. Deitmer & S. Phadhana-anek. (2018) Experience in Counting Ciliary Beat Frequency from Vital Cytologic Sampling. American Journal of Rhinology 3:3, pages 151-154.
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Michael J. Sanderson & Ellen R. Dirksen. (1989) Mechanosensitive and Beta-Adrenergic Control of the Ciliary Beat Frequency of Mammalian Respiratory Tract Cells in Culture. American Review of Respiratory Disease 139:2, pages 432-440.
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Sven Lindberg, Anders Cervin, Ulf Mercke & Rolf Uddman. (1988) VIP Potentiates Cholinergic Effects on the Mucociliary System in the Maxillary Sinus. Otolaryngology–Head and Neck Surgery 99:4, pages 401-407.
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M. L. Getchell, B. Zielinski, J. A. DeSimone & T. V. Getchell. (1987) Odorant stimulation of secretory and neural processes in the salamander olfactory mucosa. Journal of Comparative Physiology A 160:2, pages 155-168.
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Sven Lindberg, Jan Dolata & Ulf Mercke. (1986) Effects of neurokinin A and calcitonin gene-related peptide on mucociliary activity in rabbit maxillary sinus. Regulatory Peptides 16:1, pages 15-25.
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A. Rauf Khan, Bengt Bengtsson & Sven Lindberg. (1986) Influence of substance P on ciliary beat frequency in airway isolated preparations. European Journal of Pharmacology 130:1-2, pages 91-96.
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Sven Lindberg, Jan-Christer Hybbinette & Ulf Mercke. (2016) Effects of Neuropeptides on Mucociliary Activity. Annals of Otology, Rhinology & Laryngology 95:1, pages 94-100.
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Sven Lindberg & Ulf Mercke. (1985) Substance P antagonists and mucociliary activity in rabbit. Naunyn-Schmiedeberg's Archives of Pharmacology 329:4, pages 376-381.
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Michael J. Sanderson & Ellen R. Dirksen. (1985) A versatile and quantitative computer-assisted photoelectronic technique used for the analysis of ciliary beat cycles. Cell Motility 5:4, pages 267-292.
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M. Maurizi, F. Ottaviani, G. Paludetti, G. Almadori & C. Zappone. (1984) Adenoid hypertrophy and nasal mucociliary clearance in children. A morphological and functional study. International Journal of Pediatric Otorhinolaryngology 8:1, pages 31-41.
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