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Acta Oto-Laryngologica Volume 93, 1982 - Issue 1-6
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Original Article

Neomycin Concentrations in Inner Ear Tissues and Other Organs of the Guinea Pig After Chronic Drug Administration

Carol S. Desrochers Kresge Hearing Research Institute, University of Michigan, Ann Arbor, Michigan, USA
&
Jochen Schacht Kresge Hearing Research Institute, University of Michigan, Ann Arbor, Michigan, USA
Pages 233-236 | Received 18 Mar 1981, Published online: 08 Jul 2009

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J. P. Griffin. (1988) Drug-induced ototoxicity. British Journal of Audiology 22:3, pages 195-210.
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Charles M. Henley & Jochen Schacht. (1988) Pharmacokinetics of Aminoglycoside Antibiotics in Blood, Inner-Ear Fluids and Tissues and Their Relationship to Ototoxicity. Audiology 27:3, pages 137-146.
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Articles from other publishers (24)

Malene Kjelin Morsing, Inge Larsen, Ken Steen Pedersen, Nicolai Rosager Weber & Jens Peter Nielsen. (2022) Efficacy of neomycin dosing regimens for treating enterotoxigenic Escherichia coli-related post-weaning diarrhoea in a Danish nursery pig herd not using medicinal zinc oxide. Porcine Health Management 8:1.
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Caroline Grace Geary, Victoria Christina Wilk, Katherine Louise Barton, Parvaneh Ottavia Jefferson, Tea Binder, Vasvi Bhutani, Claire Luisa Baker, Achal James Fernando‐Peiris, Alexa Lee Mousley, Stefano Freitas Andrade Rozental, Hannah Mae Thompson, Justin Charles Touchon, David Justin Esteban & Hadley Creighton Bergstrom. (2021) Sex differences in gut microbiota modulation of aversive conditioning, open field activity, and basolateral amygdala dendritic spine density. Journal of Neuroscience Research 99:7, pages 1780-1801.
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Yasmina M. Abd-Elhakim, Sabry M. Abdel-Motal, Seham M. Malhat, Hend I. Mostafa, Attia A.A. Moselhy, Rasha R. Beheiry & Enas N. Said. (2021) Curcumin mitigates neurotoxic and neurobehavioral changes of gentamicin and sodium salicylate in rats by adjusting oxidative stress and apoptosis. Life Sciences 265, pages 118824.
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Jonathan I. Matsui, Jonathan E. Gale & Mark E. Warchol. (2004) Critical signaling events during the aminoglycoside‐induced death of sensory hair cells in vitro . Journal of Neurobiology 61:2, pages 250-266.
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R. Dauman & D. Dulon. (2000) Ototoxicidad medicamentosa. EMC - Otorrinolaringología 29:1, pages 1-12.
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Jeff A. Segal, Bradford D. Harris, Yelena Kustova, Anthony Basile & Phil Skolnick. (1999) Aminoglycoside neurotoxicity involves NMDA receptor activation. Brain Research 815:2, pages 270-277.
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Jeff A Segal & Phil Skolnick. (1998) Polyamine-like actions of aminoglycosides and aminoglycoside derivatives at NMDA receptors. European Journal of Pharmacology 347:2-3, pages 311-317.
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Anthony S. Basile, Jer-Min Huang, Chen Xie, Douglas Webster, Charles Berlin & Phil Skolnick. (1996) N–Methyl–D–aspartate antagonists limit aminoglycoside antibiotic–induced hearing loss. Nature Medicine 2:12, pages 1338-1343.
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Norman K. Hollenberg, Steven W. Graves, Robert B. McCall, William T. Jackson, Jerome H. Fleisch, M. Margaglione, E. Grandone, F. P. Mancini, G. Di Minno, N. Seiler, A. Hardy, J. P. Moulinoux, James Claghorn, Michael D. Lesem, Eric J. Lien, Arima Das & Linda L. LienN. Seiler, A. Hardy & J. P. Moulinoux. 1996. Progress in Drug Research/Fortschritte der Arzneimittelforschung/Progrès des recherches pharmaceutiques. Progress in Drug Research/Fortschritte der Arzneimittelforschung/Progrès des recherches pharmaceutiques 183 241 .
Sylvain Bartolami, Myriam Planche & Rémy Pujol. (1994) Effects of ototoxins on quinuclidinyl benzylate binding in the rat cochlea. Neuroscience Letters 174:2, pages 169-172.
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Andrew T. Lyos, William E. WinterIIIIII & Charles M. HenleyIIIIII. (1992) Kanamycin Inhibits Cochlear‐Renal ODC in Neonatal Rats. Otolaryngology–Head and Neck Surgery 107:4, pages 501-510.
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P J GovaertsJ ClaesP H Van de HeyningM P DerdeL KaufmanJ F MarquetM E De Broe. (1991) Effect of isepamicin dosing scheme on concentration in cochlear tissue. Antimicrobial Agents and Chemotherapy 35:11, pages 2401-2406.
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A. J. DuvallIIIIII, K. S. Robinson & S. J. Feist. (1991) Cochlear permeability of neomycin and gentamicin: an immunohistochemical study. European Archives of Oto-Rhino-Laryngology 248:6, pages 319-325.
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S. A. BROWN & J. E. RIVIERE. (2008) Comparative pharmacokinetics of aminoglycoside antibiotics. Journal of Veterinary Pharmacology and Therapeutics 14:1, pages 1-35.
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William R Lippe. (1991) Reduction and recovery of neuronal size in the cochlear nucleus of the chicken following aminoglycoside intoxication. Hearing Research 51:2, pages 193-202.
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Janique Guiramand, Marc Lenoir, Rémy Pujol & Max Récasens. (1990) Ototoxic and nephrotoxic drugs inhibit agonistinduced inositol phosphate formation in rat brain synaptoneurosomes. Toxicology Letters 51:3, pages 331-338.
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K E Fox. (1989) Total extraction of aminoglycosides from guinea pig and bullfrog tissues with sodium hydroxide or trichloroacetic acid. Antimicrobial Agents and Chemotherapy 33:4, pages 448-451.
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J. Syka. 1989. Progress in Sensory Physiology 9. Progress in Sensory Physiology 9 97 170 .
Charles M. HenleyIIIIII, Laila G. Mahran & Jochen Schacht. (1988) Inhibition of renal ornithine decarboxylase by aminoglycoside antibiotics in vitro. Biochemical Pharmacology 37:9, pages 1679-1682.
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P Tran Ba HuyD Deffrennes. (1988) Aminoglycoside binding sites in the inner ears of guinea pigs. Antimicrobial Agents and Chemotherapy 32:4, pages 467-472.
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Jochen Schacht & Thomas Van De Water. (1986) Uptake and accumulation of gentamicin in the developing inner ear of the mouse in vitro. Biochemical Pharmacology 35:16, pages 2843-2845.
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D Dulon, J M Aran, G Zajic & J Schacht. (1986) Comparative uptake of gentamicin, netilmicin, and amikacin in the guinea pig cochlea and vestibule. Antimicrobial Agents and Chemotherapy 30:1, pages 96-100.
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Jochen Schacht. (1986) Molecular mechanisms of drug-induced hearing loss. Hearing Research 22:1-3, pages 297-304.
Crossref
E. Lehnhardt. 1984. Verhandlungsbericht 1984 der Deutschen Gesellschaft für Hals- Nasen- Ohren-Heilkunde, Kopf- und Hals-Chirurgie. Verhandlungsbericht 1984 der Deutschen Gesellschaft für Hals- Nasen- Ohren-Heilkunde, Kopf- und Hals-Chirurgie 58 218 .

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