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Original Article

Ultrastructural Localization of K+-Dependent, Ouabain-Sensitive Nppase (Na-K-Atpase) In the Guinea Pig Inner Ear

Pages 277-289 | Received 27 Apr 1982, Published online: 08 Jul 2009

Keep up to date with the latest research on this topic with citation updates for this article.

Read on this site (13)

T. Yoshihara, M. Satoh, Y. Yamamura, H. Itoh, T. Ishii. (1999) Ultrastructural Localization of Glucose Transporter 1 (GLUT1) in Guinea Pig Stria Vascularis and Vestibular Dark Cell Areas: An Immunogold Study. Acta Oto-Laryngologica 119:3, pages 336-340.
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Naoyuki Kanoh, Hiroshi Ogasawara, Daisuke Mohri, Keijiro Fukazawa & Masafumi Sakagami. (1996) Cytochemical Effects of in Vitro Dopamine Treatment On the Na-Katpase Activity in Strial Marginal Cells. Acta Oto-Laryngologica 116:6, pages 824-827.
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Naoyuki Kanoh, Takeo Kumoi, Toshihiro Kobayashi, Teruhiko Okada & Harumichi Seguchi. (1993) Ultracytochemical Study of Ouabain-sensitive K+-dependent p-nitro-phenylphosphatase Activity in Stria Vascularis of Reserpinized Guinea Pigs. Acta Oto-Laryngologica 113:2, pages 142-145.
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Masafumi Sakagami, Keijiro Fukazawa, Junko Murata & Toru Matsunaga. (1993) Morphological Aspects of Transport of Potassium Ion in the Marginal Cell. Acta Oto-Laryngologica 113:sup501, pages 63-65.
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F.W. J. Albers, P. P. G. Van Benthem & J. C. M. J. De Groot. (1991) Cytochemical Localization of Ouabain-sensitive, Potassium-dependent p-nitrophenylphosphatase in the Guinea Pig Inner Ear. Acta Oto-Laryngologica 111:5, pages 885-890.
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D. S. Liu, J. Achouche, A. H. Wu, D. Trotier & P. Tran Ba Huy. (1991) Luminal Non-specific Cationic Channels in Cultured Strial Marginal Cells of Guinea Pig and Gerbil as Determined by Patch Clamp Technique. Acta Oto-Laryngologica 111:2, pages 298-303.
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Shoji Nishiyama, Eva Garcia Del Saz & Harumichi Seguchi. (1991) Carbohydrates in the Guinea Pig Stria Vascularis Demonstrated with Lectin-gold Techniques. Acta Oto-Laryngologica 111:6, pages 1041-1050.
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Toshio Yoshihara, Makoto Igarashi & Cesar D. Fermin. (1990) Ultracytochemical Localization of Na+, K+-ATPase Activity in the Tegmentum Vasculosum of the Developing Chick Cochlea. Acta Oto-Laryngologica 110:3-4, pages 366-373.
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Toshio Yoshihara, Makoto Igarashi & Cesar D. Fermin. (1990) Ultracytochemical localization of Na+, K+-ATPase Activity in the tegmentum vasculosum of the developing chick cochlea. Acta Oto-Laryngologica 110:5-6, pages 366-373.
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Takayuki Nakano & Tamotsu Morimitsu. (1988) Effects of Various Vanadium Compounds on Cochlear Potentials. Acta Oto-Laryngologica 105:sup456, pages 132-136.
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Toshio Yoshihara & Makoto Igarashi. (1987) Cytochemical Study of K+-p-Nitrophenyl Phosphatase (K+-NPPase) in Planum Semilunatum and Dark Cells of the Squirrel Monkey. Acta Oto-Laryngologica 104:1-2, pages 22-28.
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Toshio Yoshihara, Shinichi Usami, Makoto Igarashi & Cesar D. Fermin. (1987) Ultracytochemical Study of Ouabain-sensitive, Potassium-dependent p-Nitrophenylphosphatase Activity in the Inner Ear of the Squirrel Monkey. Acta Oto-Laryngologica 103:3-4, pages 161-169.
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Wei Liu & Helge Rask-Andersen. (2022) Na/K-ATPase Gene Expression in the Human Cochlea: A Study Using mRNA in situ Hybridization and Super-Resolution Structured Illumination Microscopy. Frontiers in Molecular Neuroscience 15.
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Ryan Stephenson, Astkhik Mangasarian, Gail Ishiyama, Kumiko Hosokawa, Seiji Hosokawa, Akira Ishiyama & Ivan A. Lopez. (2021) Immunohistochemical location of Na+, K+-ATPase α1 subunit in the human inner ear. Hearing Research 400, pages 108113.
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Robert Patuzzi. (2011) Ion flow in stria vascularis and the production and regulation of cochlear endolymph and the endolymphatic potential. Hearing Research 277:1-2, pages 4-19.
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Gustavo Duarte Paiva Ferreira, Maria Cristina Lancia Cury, José Antônio de Oliveira, Alessandra Kerli Manfredi & Hélio Vannucchi. (2009) Avaliação vestibular por videonistagmografia de portadores de deficiência crônica de zinco por síndrome do intestino curto. Revista Brasileira de Otorrinolaringologia 75:2, pages 290-294.
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Gustavo Duarte Paiva Ferreira, Maria Cristina Lancia Cury, José Antônio de Oliveira, Alessandra Kerli Manfredi & Hélio Vannucchi. (2009) Vestibular Evaluation Using Videonystagmography of Chronic Zinc Deficient Patients Due to Short Bowell Syndrome. Brazilian Journal of Otorhinolaryngology 75:2, pages 290-294.
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Po-Wen Cheng, Shing-Hwa Liu, Yi-Ho Young, Chuan-Jen Hsu & Shoei-Yn Lin-Shiau. (2008) Protection from Noise-Induced Temporary Threshold Shift by d-Methionine is Associated with Preservation of ATPase Activities. Ear & Hearing 29:1, pages 65-75.
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Po-Wen Cheng, Shing-Hwa Liu, Chuan-Jen Hsu & Shoei-Yn Lin-Shiau. (2005) Correlation of increased activities of Na+, K+-ATPase and Ca2+-ATPase with the reversal of cisplatin ototoxicity induced by d-methionine in guinea pigs. Hearing Research 205:1-2, pages 102-109.
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David G. Zeddies & Jonathan H. Siegel. (2004) A biophysical model of an inner hair cell. The Journal of the Acoustical Society of America 116:1, pages 426-441.
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Anderson S. Botti & Maria Cristina L. C. Féres. (2003) Íon zinco: presença no sistema auditivo. Revista Brasileira de Otorrinolaringologia 69:1, pages 111-116.
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Fred E Hossler, Francisco C Avila & George Musil. (2002) Na+,K+-ATPase activity and ultrastructural localization in the tegmentum vasculosum in the cochlea of the duckling. Hearing Research 164:1-2, pages 147-154.
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Peter C. Weber, Calhoun D. CunninghamIII,III, & Bradley A. Schulte. (2009) Potassium Recycling Pathways in the Human Cochlea. The Laryngoscope 111:7, pages 1156-1165.
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Chuan-Jen Hsu, Ching-Ting Tan, Wen-Yi Shau, Yuh-Shyang Chen, Te-Huei Yeh & Shoei Yn Lin-Shiau. (2001) Na+,K+-ATPase and Ca2+-ATPase activities in the cochlear lateral wall following surgical induction of hydrops. Hearing Research 156:1-2, pages 95-103.
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Chuan-Jen Hsu, Wen-Yi Shau, Yuh-Shyang Chen, Tien-Chen Liu & Shoei Yn Lin-Shiau. (2000) Activities of Na+,K+-ATPase and Ca2+-ATPase in cochlear lateral wall after acoustic trauma. Hearing Research 142:1-2, pages 203-211.
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Nobuki Sakaguchi, James J Crouch, Christian Lytle & Bradley A Schulte. (1998) Na-K-Cl cotransporter expression in the developing and senescent gerbil cochlea. Hearing Research 118:1-2, pages 114-122.
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Sang Jeong Kim & Steven K. Juhn. (1997) Two types of K+ currents in marginal cells cultured from rat stria vascularis. Hearing Research 112:1-2, pages 186-198.
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Th. Yeh, T. Van den Abbeele, R. Marianovski, P. Herman & P. Tran Ba Huy. (1995) Luminal non-selective cation and outwardly rectifying chloride channels in cultured strial marginal cells from gerbil. Hearing Research 90:1-2, pages 79-88.
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Ivana Magovcevic, Umang Khetarpal, Frederick R. Bieber & Cynthia C. Morton. (1995) GNAZ in human fetal cochlea: expression, localization, and potential role in inner ear function. Hearing Research 90:1-2, pages 55-64.
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Shizuo Komune, Takashi Nakagawa, Akira Inokuchi, Takashi Kimitsuki, Sohtaro Komiyama, Kenji Matsuda, Kazutaka Hisashi & Toshimitsu Kobayashi. (2016) Disturbance of Regulation of Sodium by CIS -Diamminedichloroplatinum in Perilymph of the Guinea Pig Cochlea . Annals of Otology, Rhinology & Laryngology 104:2, pages 149-154.
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S. Komune, H. Inoue, S. Wakizono, T. Nakagawa, T. Kimitsuki & T. Uemura. (1994) Profiles of resting potentials across the stria vascularis in kanamycin-deafened guinea pigs. European Archives of Oto-Rhino-Laryngology 251:S1, pages S43-S47.
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H. Kawaguchi, T. Arima & T. Uemura. (1994) Ultrastructure of guinea pig stria vascularis processed by rapid freezing and freeze substitution. European Archives of Oto-Rhino-Laryngology 251:S1, pages S33-S37.
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Naoyuki Kanoh. (2009) Reserpine inhibits the nak ATPase activity of the stria vascularis in the cochlea. The Laryngoscope 104:2, pages 197-200.
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Edmund A Mroz, Kenneth R Nissim & Claude Lechene. (1993) Rapid resting ion fluxes in goldfish hair cells are balanced by(Na+,K+)-ATPase. Hearing Research 70:1, pages 22-30.
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Wang Jian, Li Qian-hong, Dong Wei-jia & Chen Ji-sheng. (1993) Effects of K+-channel blockers on cochlear potentials in the guinea pig. Hearing Research 68:2, pages 152-158.
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Dimitri Z. Pitovski, Marian J. Drescher, Thomas P. Kerr & Dennis G. Drescher. (1993) Aldosterone mediates an increase in [3H]ouabain binding at Na+, K+ -ATPase sites in the mammalian inner ear. Brain Research 601:1-2, pages 273-278.
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Hiroshi Sunose, Katsuhisa Ikeda, Yoshitaka Saito, Akinori Nishiyama & Tomonori Takasaka. (1992) Membrane potential measurement in isolated outer hair cells of the guinea pig cochlea using conventional microelectrodes. Hearing Research 62:2, pages 237-244.
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Bradley A. Schulte & Richard A. Schmiedt. (1992) Lateral wall Na, K-ATPase and endocochlear potentials decline with age in quiet-reared gerbils. Hearing Research 61:1-2, pages 35-46.
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Leonard P. Rybak, Craig Whitworth, Aruna Weberg & Vernedra Scott. (1992) Effects of organic acids on the edema of the stria vascularis induced by furosemide. Hearing Research 59:1, pages 75-84.
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Masafumi Sakagami, Keijiro Fukazawa, Toru Matsunaga, Hisao Fujita, Nozomu Mori, Toru Takumi, Hiroaki Ohkubo & Shigetada Nakanishi. (1991) Cellular localization of rat Isk protein in the stria vascularis by immunohistochemical observation. Hearing Research 56:1-2, pages 168-172.
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Mark E. Schneider, Douglas A. Cotanche, Douglas M. Fambrough, James C. Saunders & Franz M. Matschinsky. (1987) Immunocytochemical and quantitative studies of Na+,K+-ATPase distribution in the developing chick cochlea. Hearing Research 31:1, pages 39-53.
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T. Yoshihara & M. Igarashi. (1987) Cytochemical localization of Ca++-ATPase activity in the lateral cochlear wall of the guinea pig. Archives of Oto-Rhino-Laryngology 243:6, pages 395-400.
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Ivo Melichar & Josef Syka. (1987) Electrophysiological measurements of the stria vascularis potentials in vivo. Hearing Research 25:1, pages 35-43.
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Ivo Melichar & Josef Syka. (1987) DC potentials in different cells of the stria vascularis measured in vitro. Hearing Research 25:1, pages 23-33.
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Leonard P. Rybak & Craig Whitworth. (1987) Some organic acids attenuate the effects of furosemide on the endocochlear potential. Hearing Research 26:1, pages 89-93.
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M. Tachibana, H. Morioka, M. Machino, W. Oshima, F. Mizukoshi, O. Mizukoshi & T. Yoshioka. (1984) Localization of triphosphoinositide in the cochlea. Histochemistry 81:2, pages 157-160.
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E. Lehnhardt. 1984. Verhandlungsbericht 1984 der Deutschen Gesellschaft für Hals- Nasen- Ohren-Heilkunde, Kopf- und Hals-Chirurgie. Verhandlungsbericht 1984 der Deutschen Gesellschaft für Hals- Nasen- Ohren-Heilkunde, Kopf- und Hals-Chirurgie 58 218 .
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K. Mees. (1982) Zur Lokalisation der Na-K-ATPase in der Prominentia spiralisUltrastructure localization of Na-K-ATPase in the spiral prominence. Archives of Oto-Rhino-Laryngology 235:2-3, pages 594-595.
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