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Original Article

Noise induced reversible changes of cochlear ribbon synapses contribute to temporary hearing loss in mice

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Pages 1093-1102 | Received 29 Apr 2015, Accepted 29 May 2015, Published online: 03 Jul 2015

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Colleen G. Le Prell. (2019) Effects of noise exposure on auditory brainstem response and speech-in-noise tasks: a review of the literature. International Journal of Audiology 58:sup1, pages S3-S32.
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Yan Chen, Yuyan Gu, Yige Li, Geng-Lin Li, Renjie Chai, Wenyan Li & Huawei Li. (2021) Generation of mature and functional hair cells by co-expression of Gfi1, Pou4f3, and Atoh1 in the postnatal mouse cochlea. Cell Reports 35:3, pages 109016.
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Kou-Huang Chen, Shih-Bin Su & Kow-Tong Chen. (2020) An overview of occupational noise-induced hearing loss among workers: epidemiology, pathogenesis, and preventive measures. Environmental Health and Preventive Medicine 25:1.
Crossref
Tyler T. Hickman, Ken Hashimoto, Leslie D. Liberman & M. Charles Liberman. (2020) Synaptic migration and reorganization after noise exposure suggests regeneration in a mature mammalian cochlea. Scientific Reports 10:1.
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Stephanie L. Rouse, Ian R. Matthews, Jiang Li, Elliott H. Sherr & Dylan K. Chan. (2020) Integrated stress response inhibition provides sex-dependent protection against noise-induced cochlear synaptopathy. Scientific Reports 10:1.
Crossref
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Crossref
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Crossref
Zhen Zhang, Liqiang Fan, Yazhi Xing, Jiping Wang, Steve Aiken, Zhengnong Chen & Jian Wang. (2020) Temporary Versus Permanent Synaptic Loss from Repeated Noise Exposure in Guinea Pigs and C57 Mice. Neuroscience 432, pages 94-103.
Crossref
Shuguang Han, Zhengde Du, Ke Liu & Shusheng Gong. (2020) Nicotinamide riboside protects noise-induced hearing loss by recovering the hair cell ribbon synapses. Neuroscience Letters 725, pages 134910.
Crossref
Yangtuo Luo, Tengfei Qu, Qingling Song, Yue Qi, Shukui Yu, Shusheng Gong, Ke Liu & Xuejun Jiang. (2020) Repeated Moderate Sound Exposure Causes Accumulated Trauma to Cochlear Ribbon Synapses in Mice. Neuroscience 429, pages 173-184.
Crossref
David C. Kohrman, Guoqiang Wan, Luis Cassinotti & Gabriel Corfas. (2020) Hidden Hearing Loss: A Disorder with Multiple Etiologies and Mechanisms. Cold Spring Harbor Perspectives in Medicine 10:1, pages a035493.
Crossref
Kevin K. Ohlemiller & Christopher Spankovich. 2020. Aging and Hearing. Aging and Hearing 35 66 .
Kevin K. Ohlemiller. (2019) Mouse methods and models for studies in hearing. The Journal of the Acoustical Society of America 146:5, pages 3668-3680.
Crossref
Tonghui Ding, Aihui Yan & Ke Liu. (2019) What is noise-induced hearing loss?. British Journal of Hospital Medicine 80:9, pages 525-529.
Crossref
Huihui Liu, Jiawen Lu, Zhongying Wang, Lei Song, Xueling Wang, Geng-Lin Li & Hao Wu. (2019) Functional alteration of ribbon synapses in inner hair cells by noise exposure causing hidden hearing loss. Neuroscience Letters 707, pages 134268.
Crossref
Tejbeer Kaur, Anna C. Clayman, Andrew J. Nash, Angela D. Schrader, Mark E. Warchol & Kevin K. Ohlemiller. (2019) Lack of Fractalkine Receptor on Macrophages Impairs Spontaneous Recovery of Ribbon Synapses After Moderate Noise Trauma in C57BL/6 Mice. Frontiers in Neuroscience 13.
Crossref
Elizabeth L. Wagner & Jung-Bum Shin. (2019) Mechanisms of Hair Cell Damage and Repair. Trends in Neurosciences 42:6, pages 414-424.
Crossref
Hengchao Chen, Lijuan Shi, Lijie Liu, Shankai Yin, Steven Aiken & Jian Wang. (2019) Noise-induced Cochlear Synaptopathy and Signal Processing Disorders. Neuroscience 407, pages 41-52.
Crossref
Huihui Liu, Gen Li, Jiawen Lu, Yun-Ge Gao, Lei Song, Geng-Lin Li & Hao Wu. (2019) Cellular Differences in the Cochlea of CBA and B6 Mice May Underlie Their Difference in Susceptibility to Hearing Loss. Frontiers in Cellular Neuroscience 13.
Crossref
Hengchao Chen, Yazhi Xing, Zhen Zhang, Shan Tao, Hui Wang, Steve Aiken, Shankai Yin, Dongzhen Yu & Jian Wang. (2019) Coding-in-Noise Deficits are Not Seen in Responses to Amplitude Modulation in Subjects with cochlear Synaptopathy Induced by a Single Noise Exposure. Neuroscience 400, pages 62-71.
Crossref
Anwen Bullen, Lucy Anderson, Warren Bakay & Andrew Forge. (2019) Localized disorganization of the cochlear inner hair cell synaptic region after noise exposure. Biology Open 8:1.
Crossref
Hengchao Chen, Yazhi Xing, Li Xia, Zhengnong Chen, Shankai Yin & Jian Wang. (2018) AAV-mediated NT-3 overexpression protects cochleae against noise-induced synaptopathy. Gene Therapy 25:4, pages 251-259.
Crossref
Guang-Di Chen. (2018) Hidden cochlear impairments. Journal of Otology 13:2, pages 37-43.
Crossref
Garreth Prendergast, Rebecca E. Millman, Hannah Guest, Kevin J. Munro, Karolina Kluk, Rebecca S. Dewey, Deborah A. Hall, Michael G. Heinz & Christopher J. Plack. (2017) Effects of noise exposure on young adults with normal audiograms II: Behavioral measures. Hearing Research 356, pages 74-86.
Crossref
Wen-wei Luo, Rui Ma, Xiang Cheng, Xiao-yu Yang, Zhao Han, Dong-dong Ren, Ping Chen, Fang-lu Chi & Juan-mei Yang. (2017) Afferent synaptogenesis between ectopic hair-cell-like cells and neurites of spiral ganglion induced by Atoh1 in mammals in vitro. Neuroscience 357, pages 185-196.
Crossref
Xiaoping Du, Matthew B. West, Qunfeng Cai, Weihua Cheng, Donald L. Ewert, Wei Li, Robert A. Floyd & Richard D. Kopke. (2017) Antioxidants reduce neurodegeneration and accumulation of pathologic Tau proteins in the auditory system after blast exposure. Free Radical Biology and Medicine 108, pages 627-643.
Crossref
M. Charles Liberman & Sharon G. Kujawa. (2017) Cochlear synaptopathy in acquired sensorineural hearing loss: Manifestations and mechanisms. Hearing Research 349, pages 138-147.
Crossref
Jos J. Eggermont. 2017. Hearing Loss. Hearing Loss 129 173 .
Kevin K. Ohlemiller, Sherri M. Jones & Kenneth R. Johnson. (2016) Application of Mouse Models to Research in Hearing and Balance. Journal of the Association for Research in Otolaryngology 17:6, pages 493-523.
Crossref
Otto Gleich, Philipp Semmler & Jürgen Strutz. (2016) Behavioral auditory thresholds and loss of ribbon synapses at inner hair cells in aged gerbils. Experimental Gerontology 84, pages 61-70.
Crossref
Lijuan Shi, Yin Chang, Xiaowei Li, Steven J. Aiken, Lijie Liu & Jian Wang. (2016) Coding Deficits in Noise-Induced Hidden Hearing Loss May Stem from Incomplete Repair of Ribbon Synapses in the Cochlea. Frontiers in Neuroscience 10.
Crossref
Qiang Song, Pei Shen, Xiaowei Li, Lijuan Shi, Lijie Liu, Jiping Wang, Zhiping Yu, Kegan Stephen, Steve Aiken, Shankai Yin & Jian Wang. (2016) Coding deficits in hidden hearing loss induced by noise: the nature and impacts. Scientific Reports 6:1.
Crossref
A.N. Heeringa, R.A. Stefanescu, Y. Raphael & S.E. Shore. (2016) Altered vesicular glutamate transporter distributions in the mouse cochlear nucleus following cochlear insult. Neuroscience 315, pages 114-124.
Crossref
Lijuan Shi, Ying Chang, Xiaowei Li, Steve Aiken, Lijie Liu & Jian Wang. (2016) Cochlear Synaptopathy and Noise-Induced Hidden Hearing Loss. Neural Plasticity 2016, pages 1-9.
Crossref
Xiaoling Lu, Yilai Shu, Mingliang Tang & Huawei Li. (2016) Mammalian Cochlear Hair Cell Regeneration and Ribbon Synapse Reformation. Neural Plasticity 2016, pages 1-9.
Crossref

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