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Acta Oto-Laryngologica Volume 135, 2015 - Issue 12
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Review

Use of betahistine in the treatment of peripheral vertigo

Rubén Ramos AlcocerOtorrinolaringologo y Neurotologo, Medicentro del Parque, San Luis Potosí S.L.P, MéxicoCorrespondence[email protected]
,
José Gregorio Ledezma RodríguezORL, Otoneurología, Fundación Venezolana de Otología, Instituto de Otorrinolaringología y Oftalmología, Hospital Militar Dr Carlos Arvelo, Caracas, Venezuela
,
Antonio Navas RomeroMédico Otorrinolaringólogo-Neurootólogo, Servicio de ORL, Dirección General de Aviación Civil, Director de la clínica del vértigo y acúfenos, Quito, Ecuador
,
José Luis Cardenas NuñezProfesor Titular de Neurologia, Facultad de Ciencias Médicas, Universidad de Santiago de Chile, Centro de Medicina Aeroespacial, Fuerza Aérea de Chile, Las Condes, Santiago de Chile
,
Vicente Rodríguez MontoyaOtorrinolaringólogo-Otólogo, Clínica del Country, Clínica La Colina, Bogotá, Colombia
,
Jose Junior DeschampsCentro de Otorrinolaringología y Especialidades, Universidad autónoma de Santo Domingo, República Dominicana
&
Jorge Anibal Liviac TicseNeurología, Clínica privada Jorge Anibal Liviac Ticse, Lima, Peru
 show all
Pages 1205-1211 | Received 27 May 2015, Accepted 08 Jul 2015, Published online: 06 Aug 2015

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Andreas Zwergal, Michael Strupp & Thomas Brandt. (2019) Advances in pharmacotherapy of vestibular and ocular motor disorders. Expert Opinion on Pharmacotherapy 20:10, pages 1267-1276.
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Elise Jacquin, Stéphanie Leclerc-Mercier, Celine Judon, Emmanuelle Blanchard, Sylvie Fraitag & Oliver Florey. (2017) Pharmacological modulators of autophagy activate a parallel noncanonical pathway driving unconventional LC3 lipidation. Autophagy 13:5, pages 854-867.
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Articles from other publishers (24)

Benedikt Kloos, Mattis Bertlich, Jennifer L. Spiegel, Saskia Freytag, Susanne K. Lauer, Martin Canis, Bernhard G. Weiss & Friedrich Ihler. (2022) Low Dose Betahistine in Combination With Selegiline Increases Cochlear Blood Flow in Guinea Pigs. Annals of Otology, Rhinology & Laryngology 132:5, pages 519-526.
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Muhammad Talha, Somiya Asif, Hamza Shahid, Syeda Maria Nazir & Kiran Haq. (2023) Comparison of RPM (Re-positioning Maneuver) & Liberatory maneuvers vs Betahistine on BPPV (Benign Paroxysmal Positional Vertigo) for improving functional ability and quality of life. Pakistan Journal of Health Sciences, pages 54-58.
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Wei Li, Jinqiang Sun, Zeqi Zhao, Jifeng Xu, Hao Wang, Rui Ding & Yanqiu Zhang. (2023) Efficacy of Epley’s maneuver plus betahistine in the management of PC-BPPV: A systematic review and meta-analysis. Medicine 102:13, pages e33421.
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Katie E Webster, Kevin Galbraith, Natasha A Harrington-Benton, Owen Judd, Diego Kaski, Otto R Maarsingh, Samuel MacKeith, Jaydip Ray, Vincent A Van Vugt & Martin J Burton. (2023) Systemic pharmacological interventions for Ménière’s disease. Cochrane Database of Systematic Reviews 2023:2.
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Michael Strupp, Thomas Brandt & Marianne DieterichMichael Strupp, Thomas Brandt & Marianne Dieterich. 2023. Vertigo and Dizziness. Vertigo and Dizziness 181 202 .
Makoto Hashimoto, Izumi Koizuka, Hiroshi Yamashita, Mamoru Suzuki, Koichi Omori, Hideki Origasa, Noriaki Takeda & Hideo Shojaku. (2022) Diagnostic and therapeutic strategies for vestibular neuritis of the Japan society for equilibrium research. Auris Nasus Larynx.
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Wan Ahmad Amiruddin Wan Hassan, Khairul Ridhwan Mohd Nasir Mohd Nasir, Saiful Adli Jamaluddin, Edre Mohammad Aidid & Yahia F Hussein Al-Hadeethi. (2022) Effects of Betahistine on Vestibulo-Ocular Reflex in Normal Healthy Adults: A Randomized Double-Blind, Placebo-Controlled Trial. Cureus.
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Ibrahim Sayin, Recep Haydar Koç, Dastan Temirbekov, Selcuk Gunes, Musa Cirak & Zahide Mine Yazici. (2022) Betahistine add-on therapy for treatment of subjects with posterior benign paroxysmal positional vertigo: a randomized controlled trial. Brazilian Journal of Otorhinolaryngology 88:3, pages 421-426.
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Chang Hoon Bae, Hyung Gyun Na & Yoon Seok Choi. (2022) Current diagnosis and treatment of vestibular neuritis: a narrative review. Journal of Yeungnam Medical Science 39:2, pages 81-88.
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Beyza ASLAN, Hasan DEMİRHAN, İlknur YASAK, Özgür YİĞİT & Yıldırım BAYAZIT. (2022) Does the use of betahistine dihydrochloride affect positional nystagmus?Betahistin dihidroklorür kullanımı pozisyonel nistagmusu etkiler mi?. Anadolu Kliniği Tıp Bilimleri Dergisi 27:1, pages 45-48.
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Klaus Hager & Roland Seifert. 2022. Arzneiverordnungs-Report 2022. Arzneiverordnungs-Report 2022 553 558 .
Giulio Di Mizio, Gianmarco Marcianò, Caterina Palleria, Lucia Muraca, Vincenzo Rania, Roberta Roberti, Giuseppe Spaziano, Amalia Piscopo, Valeria Ciconte, Nunzio Di Nunno, Massimiliano Esposito, Pasquale Viola, Davide Pisani, Giovambattista De Sarro, Milena Raffi, Alessandro Piras, Giuseppe Chiarella & Luca Gallelli. (2021) Drug–Drug Interactions in Vestibular Diseases, Clinical Problems, and Medico-Legal Implications. International Journal of Environmental Research and Public Health 18:24, pages 12936.
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Giampiero NERI, Luigi CALIFANO & Vincenzo MARCELLI. (2021) Comparison between mesoglycan and betahistine in the treatment of vertigo and dizziness in elderly patients. Otorhinolaryngology 71:2.
Crossref
Vijay D. Chavada, Nejal M. Bhatt, Mallika Sanyal & Pranav S. Shrivastav. (2020) Modulation of inner filter effect of non-conjugated silver nanoparticles on blue emitting ZnS quantum dots for the quantitation of betahistine. Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy 240, pages 118575.
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A. L. Guseva, S. A. MakarovG. M. Dyukova & V. L. Golubev. (2020) Clinical and diagnostic approach to patient with vertigo and dizziness. Medical alphabet:1, pages 15-20.
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Mir Mohammad Jalali, Hooshang Gerami, Alia Saberi & Siavash Razaghi. (2019) The Impact of Betahistine versus Dimenhydrinate in the Resolution of Residual Dizziness in Patients with Benign Paroxysmal Positional Vertigo: A Randomized Clinical Trial. Annals of Otology, Rhinology & Laryngology 129:5, pages 434-440.
Crossref
Gregory J. Basura, Meredith E. Adams, Ashkan Monfared, Seth R. Schwartz, Patrick J. Antonelli, Robert Burkard, Matthew L. Bush, Julie Bykowski, Maria Colandrea, Jennifer Derebery, Elizabeth A. Kelly, Kevin A. Kerber, Charles F. Koopman, Amy Angie Kuch, Evie Marcolini, Brian J. McKinnon, Michael J. Ruckenstein, Carla V. Valenzuela, Alexis Vosooney, Sandra A. Walsh, Lorraine C. Nnacheta, Nui Dhepyasuwan & Erin M. Buchanan. (2020) Clinical Practice Guideline: Ménière’s Disease. Otolaryngology–Head and Neck Surgery 162:S2.
Crossref
Duaa J. Al-Tamimi, Afaq M. Ammoo, Mays E. Alani & Jaafar J. Ibraheem. (2020) Pharmacokinetics and Dose Proportionality of Betahistine in Healthy Individuals. Scientia Pharmaceutica 88:1, pages 13.
Crossref
Payman Asadi, Seyyed Mahdi Zia Ziabari, Alireza Majdi, Karim Vatanparast & Seyed Ahmad Naseri Alavi. (2019) Cinnarizine/betahistine combination vs. the respective monotherapies in acute peripheral vertigo: a randomized triple-blind placebo-controlled trial. European Journal of Clinical Pharmacology 75:11, pages 1513-1519.
Crossref
Jonas Dyhrfjeld‐Johnsen & Pierre Attali. (2019) Management of peripheral vertigo with antihistamines: New options on the horizon. British Journal of Clinical Pharmacology 85:10, pages 2255-2263.
Crossref
Kanwaljit Singh, Sowjanya Potturu, Katy Madden & James Murray. (2019) Betahistine-associated anticholinergic activity-type side effects. European Geriatric Medicine 10:4, pages 675-676.
Crossref
Zhang-Peng Chen, Xiao-Yang Zhang, Shi-Yu Peng, Zhong-Qin Yang, Yan-Bo Wang, Yang-Xun Zhang, Xi Chen, Jian-Jun Wang & Jing-Ning Zhu. (2019) Histamine H1 Receptor Contributes to Vestibular Compensation. The Journal of Neuroscience 39:3, pages 420-433.
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D. A. Shcherbakov, R. A. Raemgulov, K. P. Bukharova & I. A. Dyukova. (2018) The effectiveness of the intra-tympanic administration of methylprednisolone and gentamycin for the treatment of Meniere's disease. Vestnik otorinolaringologii 83:5, pages 17.
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Krunal Soni, Chandrakant Bhatt, Kanchan Singh, P.C. Bhuvaneshwari, Anil Jha, Palak Patel, Harilal Patel & Nuggehally R. Srinivas. (2017) An LC-MS/MS assay for the quantitative determination of 2-pyridyl acetic acid, a major metabolite and key surrogate for betahistine, using low-volume human K 2 EDTA plasma . Biomedical Chromatography 31:2, pages e3790.
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