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Research Article

DNA Damage and Impairment of DNA Repair in Alzheimer's Disease

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Pages 397-403 | Received 01 Sep 2009, Published online: 26 May 2010

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M. Obulesu & M. Jhansilakshmi. (2014) Neuroinflammation in Alzheimer's disease: an understanding of physiology and pathology. International Journal of Neuroscience 124:4, pages 227-235.
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M. Obulesu, R. Somashekhar & R. Venu. (2011) Genetics of Alzheimer's Disease: An Insight Into Presenilins and Apolipoprotein E Instigated Neurodegeneration. International Journal of Neuroscience 121:5, pages 229-236.
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Articles from other publishers (24)

Rajesh Ranganathan, Georgy Sapozhnikov, Wang Ni, Siwen Li & Youqiang Song. (2023) Recent developments in the role of DNA damage response and understanding its implications for new therapeutic approaches in Alzheimer's disease. Translational Medicine of Aging 7, pages 52-65.
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Aditi & Peter J. McKinnon. (2022) Genome integrity and inflammation in the nervous system. DNA Repair 119, pages 103406.
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Diana Iulia Savu & Nicoleta Moisoi. (2022) Mitochondria - Nucleus communication in neurodegenerative disease. Who talks first, who talks louder?. Biochimica et Biophysica Acta (BBA) - Bioenergetics 1863:7, pages 148588.
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Jelena Dimitrijevic, Aleksandar Arsenijevic, Marija Milovanovic, Bojana Stojanovic, Dragana Arsenijevic, Jelena Milovanovic & Nebojsa Arsenijevic. (2021) Role of IL-33/ST2 Axis in Chronic Inflammatory Neurological Disorderss. Serbian Journal of Experimental and Clinical Research 0:0.
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Björn Schumacher, Joris Pothof, Jan Vijg & Jan H. J. Hoeijmakers. (2021) The central role of DNA damage in the ageing process. Nature 592:7856, pages 695-703.
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Amitha Kurian & Preetham Elumalai. (2021) Study on the impacts of chemical and green synthesized (Leucas aspera and oxy-cyclodextrin complex) dietary zinc oxide nanoparticles in Nile tilapia (Oreochromis niloticus). Environmental Science and Pollution Research 28:16, pages 20344-20361.
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Magisetty Obulesu. 2020. Parkinson's Disease Therapeutics. Parkinson's Disease Therapeutics 1 11 .
Magisetty Obulesu. 2019. Alzheimer's Disease Theranostics. Alzheimer's Disease Theranostics 1 6 .
Anna Konopka & Julie Atkin. (2018) The Emerging Role of DNA Damage in the Pathogenesis of the C9orf72 Repeat Expansion in Amyotrophic Lateral Sclerosis. International Journal of Molecular Sciences 19:10, pages 3137.
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Yujun HouSofie LautrupStephanie CordonnierYue WangDeborah L. CroteauEduardo ZavalaYongqing ZhangKanako MoritohJennifer F. O’ConnellBeverly A. BaptisteTinna V. StevnsnerMark P. MattsonVilhelm A. Bohr. (2018) NAD + supplementation normalizes key Alzheimer’s features and DNA damage responses in a new AD mouse model with introduced DNA repair deficiency . Proceedings of the National Academy of Sciences 115:8.
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C Carlock, J Wu, J Shim, I Moreno-Gonzalez, M R Pitcher, J Hicks, A Suzuki, J Iwata, J Quevado & Y Lou. (2017) Interleukin33 deficiency causes tau abnormality and neurodegeneration with Alzheimer-like symptoms in aged mice. Translational Psychiatry 7:7, pages e1164-e1164.
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Gonca Alak, Aslı Çilingir Yeltekin, Ismail Hakkı Tas, Arzu Ucar, Veysel Parlak, Ahmet Topal, Esat Mahmut Kocaman & Muhammed Atamanalp. (2017) Investigation of 8-OHdG, CYP1A, HSP70 and transcriptional analyses of antioxidant defence system in liver tissues of rainbow trout exposed to eprinomectin. Fish & Shellfish Immunology 65, pages 136-144.
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Yujun Hou, Hyundong Song, Deborah L. Croteau, Mansour Akbari & Vilhelm A. Bohr. (2017) Genome instability in Alzheimer disease. Mechanisms of Ageing and Development 161, pages 83-94.
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Obulesu Magisetty, Muralidhara Rao Dowlathabad, Keshav P. Raichurkar & Shamasundar N. Mannar. (2016) First magenetic resonance imaging studies on aluminium maltolate-treated aged New Zealand rabbits: an Alzheimer's animal model. Psychogeriatrics 16:4, pages 263-267.
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M. Obulesu & M. Jhansi Lakshmi. (2014) Apoptosis in Alzheimer’s Disease: An Understanding of the Physiology, Pathology and Therapeutic Avenues. Neurochemical Research 39:12, pages 2301-2312.
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Carolin CorneliusRosalia CrupiVittorio CalabreseAntonio GrazianoPietro MiloneGiovanni PennisiZsolt RadakEdward J. CalabreseSalvatore Cuzzocrea. (2013) Traumatic Brain Injury: Oxidative Stress and Neuroprotection. Antioxidants & Redox Signaling 19:8, pages 836-853.
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Ilaria Penna, Irene Vassallo, Mario Nizzari, Debora Russo, Delfina Costa, Paola Menichini, Alessandro Poggi, Claudio Russo, Giorgio Dieci, Tullio Florio, Ranieri Cancedda & Aldo Pagano. (2013) A novel snRNA-like transcript affects amyloidogenesis and cell cycle progression through perturbation of Fe65L1 (APBB2) alternative splicing. Biochimica et Biophysica Acta (BBA) - Molecular Cell Research 1833:6, pages 1511-1526.
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Charlotte Delay, Wim Mandemakers & Sébastien S. Hébert. (2012) MicroRNAs in Alzheimer's disease. Neurobiology of Disease 46:2, pages 285-290.
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Muralidhar L. Hegde, Tadahide Izumi & Sankar Mitra. 2012. Mechanisms of DNA Repair. Mechanisms of DNA Repair 123 153 .
M. Obulesu, R. Venu & R. Somashekhar. (2011) Lipid peroxidation in Alzheimer’s Disease: emphasis on metal-mediated neurotoxicity. Acta Neurologica Scandinavica 124:5, pages 295-301.
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M. Obulesu, Muralidhara Rao Dowlathabad & P.V. Bramhachari. (2011) Carotenoids and Alzheimer’s Disease: An insight into therapeutic role of retinoids in animal models. Neurochemistry International 59:5, pages 535-541.
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Zsolt Radak, Zhongfu Zhao, Sataro Goto & Erika Koltai. (2011) Age-associated neurodegeneration and oxidative damage to lipids, proteins and DNA. Molecular Aspects of Medicine 32:4-6, pages 305-315.
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M. Obulesu, R. Venu & R. Somashekhar. (2011) Tau Mediated Neurodegeneration: An Insight into Alzheimer’s Disease Pathology. Neurochemical Research 36:8, pages 1329-1335.
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Dick F. Swaab & Ai-Min Bao. (2011) (Re-)activation of neurons in aging and dementia: Lessons from the hypothalamus. Experimental Gerontology 46:2-3, pages 178-184.
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