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Research Article

Study of Methylation Levels of Parkin Gene Promoter in Parkinson's Disease Patients

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Pages 497-502 | Received 19 Dec 2010, Published online: 10 Jun 2011

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Isil Ezgi Eryilmaz, Gulsah Cecener, Sevda Erer, Unal Egeli, Berrin Tunca, Mehmet Zarifoglu, Bulent Elibol, Ayse Bora Tokcaer, Esen Saka, Meltem Demirkiran, Cenk Akbostanci, Okan Dogu, Beril Colakoglu, Gulay Kenangil & Hakan Kaleagasi. (2017) Epigenetic approach to early-onset Parkinson’s disease: low methylation status of SNCA and PARK2 promoter regions. Neurological Research 39:11, pages 965-972.
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Dan Zhang, Jifa Zhang, Yuxi Wang, Guan Wang, Pan Tang, Yun Liu, Yiwen Zhang & Liang Ouyang. (2023) Targeting epigenetic modifications in Parkinson's disease therapy. Medicinal Research Reviews 43:5, pages 1748-1777.
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P. Ghosh & A. Saadat. (2023) Neurodegeneration and epigenetics: A review. Neurología (English Edition) 38:6, pages e62-e68.
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P. Ghosh & A. Saadat. (2023) Neurodegeneration and epigenetics: A review. Neurología 38:6, pages e62-e68.
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Hao Song, Juanli Chen, Jin Huang, Peng Sun, Yanming Liu, Li Xu, Chuanfei Wei, Xin Mu, Xianjie Lu, Wei Wang, Nan Zhang, Miwei Shang, Mei Mo, Wei Zhang, Hui Zhao & Fabin Han. (2023) Epigenetic modification in Parkinson’s disease. Frontiers in Cell and Developmental Biology 11.
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Volkan Yazar, Valina L. Dawson, Ted M. Dawson & Sung-Ung Kang. (2023) DNA Methylation Signature of Aging: Potential Impact on the Pathogenesis of Parkinson’s Disease. Journal of Parkinson's Disease 13:2, pages 145-164.
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Bhairavi Srinageshwar, Gary L. Dunbar & Julien Rossignol. 2023. Handbook of Epigenetics. Handbook of Epigenetics 381 401 .
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Gagandeep Kaur, Suraj Singh S. Rathod, Mohammed M. Ghoneim, Sultan Alshehri, Javed Ahmad, Awanish Mishra & Nabil A. Alhakamy. (2022) DNA Methylation: A Promising Approach in Management of Alzheimer’s Disease and Other Neurodegenerative Disorders. Biology 11:1, pages 90.
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Jie Meng, Fenglin Wang, Lei Ji, Yuhua Liang, Wei Nian, Lele Song & Aiqin Zhu. (2021) Comprehensive methylation profile of CSF cfDNA revealed pathogenesis and diagnostic markers for early-onset Parkinson's disease. Epigenomics 13:20, pages 1637-1651.
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Hyojung Kim, Seok-Jae Kang, Young Mi Jo, Sanggyu Park, Seung Pil Yun, Yun-Song Lee, Hee-Tae Kim, Nae-Eung Lee, Yong-Sang Kim, Seok Hyun Cho & Yunjong Lee. (2020) Novel Nasal Epithelial Cell Markers of Parkinson’s Disease Identified Using Cells Treated with α-Synuclein Preformed Fibrils. Journal of Clinical Medicine 9:7, pages 2128.
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Aintzane Urbizu & Katrin Beyer. (2020) Epigenetics in Lewy Body Diseases: Impact on Gene Expression, Utility as a Biomarker, and Possibilities for Therapy. International Journal of Molecular Sciences 21:13, pages 4718.
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Li Shu, Lixia Qin, Shishi Min, Hongxu Pan, Junfei Zhong, Jifeng Guo, Qiying Sun, Xinxiang Yan, Chao Chen, Beisha Tang & Qian Xu. (2019) Genetic analysis of DNA methylation and hydroxymethylation genes in Parkinson's disease. Neurobiology of Aging 84, pages 242.e13-242.e16.
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Hyojung Kim, Seok-Jae Kang, Young Mi Jo, Min Song Kim, Yunjong Lee, Seok-Hyun Cho & Hee-Tae Kim. (2019) Quantitative analysis of nasal transcripts reveals potential biomarkers for Parkinson’s disease. Scientific Reports 9:1.
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Luis Navarro-Sánchez, Beatriz Águeda-Gómez, Silvia Aparicio & Jordi Pérez-Tur. (2018) Epigenetic Study in Parkinson’s Disease: A Pilot Analysis of DNA Methylation in Candidate Genes in Brain. Cells 7:10, pages 150.
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Xuan Liu, Jie Yang, Qin Zhang & Li Jiang. (2017) Regulation of DNA methylation on EEF1D and RPL8 expression in cattle. Genetica 145:4-5, pages 387-395.
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Ernesto Miranda-Morales, Karin Meier, Ada Sandoval-Carrillo, José Salas-Pacheco, Paola Vázquez-Cárdenas & Oscar Arias-Carrión. (2017) Implications of DNA Methylation in Parkinson’s Disease. Frontiers in Molecular Neuroscience 10.
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Bhairavi Srinageshwar, Panchanan Maiti, Gary L. Dunbar & Julien Rossignol. 2017. Handbook of Epigenetics. Handbook of Epigenetics 323 338 .
Maria Angeliki S. Pavlou & Tiago Fleming Outeiro. 2017. Neuroepigenomics in Aging and Disease. Neuroepigenomics in Aging and Disease 363 390 .
Ke-xin Wen, Jelena Miliç, Bassem El-Khodor, Klodian Dhana, Jana Nano, Tammy Pulido, Bledar Kraja, Asija Zaciragic, Wichor M. Bramer, John Troup, Rajiv Chowdhury, M. Arfam Ikram, Abbas Dehghan, Taulant Muka & Oscar H. Franco. (2016) The Role of DNA Methylation and Histone Modifications in Neurodegenerative Diseases: A Systematic Review. PLOS ONE 11:12, pages e0167201.
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Ullrich Wüllner, Oliver Kaut, Laura deBoni, Dominik Piston & Ina Schmitt. (2016) DNA methylation in Parkinson's disease. Journal of Neurochemistry 139, pages 108-120.
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Michel Neidhart. 2016. DNA Methylation and Complex Human Disease. DNA Methylation and Complex Human Disease 289 314 .
Graziella Rubino. (2015) Complex liaisons moving forward the Parkinson’s disease? An appraisal. Basal Ganglia 5:4, pages 77-87.
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Shariq I. Sherwani & Haseeb A. Khan. (2015) Role of 5-hydroxymethylcytosine in neurodegeneration. Gene 570:1, pages 17-24.
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Roy Lardenoije, Artemis Iatrou, Gunter Kenis, Konstantinos Kompotis, Harry W.M. Steinbusch, Diego Mastroeni, Paul Coleman, Cynthia A. Lemere, Patrick R. Hof, Daniel L.A. van den Hove & Bart P.F. Rutten. (2015) The epigenetics of aging and neurodegeneration. Progress in Neurobiology 131, pages 21-64.
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Mawussi Adjakly, Marjolaine Ngollo, Aslihan Dagdemir, Gaëlle Judes, Amaury Pajon, Seher Karsli-Ceppioglu, Frédérique Penault-Llorca, Jean-Paul Boiteux, Yves-Jean Bignon, Laurent Guy & Dominique Bernard-Gallon. (2015) Prostate cancer: The main risk and protective factors – Epigenetic modifications. Annales d'Endocrinologie 76:1, pages 25-41.
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Nadella Kumudini, Addepally Uma, Shaik Mohammad Naushad, Rukmini Mridula, Rupam Borgohain & Vijay Kumar Kutala. (2014) Association of seven functional polymorphisms of one-carbon metabolic pathway with total plasma homocysteine levels and susceptibility to Parkinson's disease among South Indians. Neuroscience Letters 568, pages 1-5.
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Lorena De Mena, Lucía F. Cardo, Eliecer Coto, Victoria Alvarez & Eliecer Coto. (2013) No differential DNA methylation of PARK2 in brain of Parkinson's disease patients and healthy controls . Movement Disorders 28:14, pages 2032-2033.
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Navneet Ammal Kaidery, Shaista Tarannum & Bobby Thomas. (2013) Epigenetic Landscape of Parkinson’s Disease: Emerging Role in Disease Mechanisms and Therapeutic Modalities. Neurotherapeutics 10:4, pages 698-708.
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Ana B Crujeiras, Javier Campion, Angel Díaz-Lagares, Fermin I Milagro, Estíbaliz Goyenechea, Itziar Abete, Felipe F Casanueva & J. Alfredo Martínez. (2013) Association of weight regain with specific methylation levels in the NPY and POMC promoters in leukocytes of obese men: A translational study. Regulatory Peptides 186, pages 1-6.
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Fabio Copped?. (2012) Genetics and Epigenetics of Parkinson's Disease. The Scientific World Journal 2012, pages 1-12.
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