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Research Article

Meta-Analysis of the Cystatin C(CST3) Gene G73A Polymorphism and Susceptibility to Alzheimer's Disease

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Pages 431-438 | Received 01 Dec 2011, Published online: 20 Apr 2012

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Fakhra Amin, Mohd Shahnawaz Khan & Bilqees Bano. (2020) Mammalian cystatin and protagonists in brain diseases. Journal of Biomolecular Structure and Dynamics 38:7, pages 2171-2196.
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Jingrong Luo, Shan Li, Xue Qin, Qiliu Peng, Yanqiong Liu, Shi Yang, Xuejun Qin, Yuqing Xiong & Zhiyu Zeng. (2016) Association of the NQO1 C609T polymorphism with Alzheimer's disease in Chinese populations: a meta-analysis. International Journal of Neuroscience 126:3, pages 199-204.
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Emil Carlsson, Umar Sharif, Wasu Supharattanasitthi & Luminita Paraoan. (2023) Analysis of Wild Type and Variant B Cystatin C Interactome in Retinal Pigment Epithelium Cells Reveals Variant B Interacting Mitochondrial Proteins. Cells 12:5, pages 713.
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Stella A. Belonwu, Yaqiao Li, Daniel G. Bunis, Arjun Arkal Rao, Caroline Warly Solsberg, Tomiko Oskotsky, Alice L. Taubes, Brian Grone, Kelly A. Zalocusky, Gabriela K. Fragiadakis, Yadong Huang & Marina Sirota. (2022) Bioinformatics Analysis of Publicly Available Single-Nuclei Transcriptomics Alzheimer’s Disease Datasets Reveals APOE Genotype-Specific Changes Across Cell Types in Two Brain Regions. Frontiers in Aging Neuroscience 14.
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Xueping Chen, Yan Huang, Ting Bao, Fu Jia, Ruwei Ou, Qianqian Wei, Yongping Chen, Jiao Liu, Jing Yang & Huifang Shang. (2022) Changes in Serum Cystatin C Levels and the Associations With Cognitive Function in Alzheimer's Disease Patients. Frontiers in Aging Neuroscience 13.
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Stella A. Belonwu, Yaqiao Li, Daniel Bunis, Arjun Arkal Rao, Caroline Warly Solsberg, Alice Tang, Gabriela K. Fragiadakis, Dena B. Dubal, Tomiko Oskotsky & Marina Sirota. (2021) Sex-Stratified Single-Cell RNA-Seq Analysis Identifies Sex-Specific and Cell Type-Specific Transcriptional Responses in Alzheimer’s Disease Across Two Brain Regions. Molecular Neurobiology 59:1, pages 276-293.
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Xuewen Xiao, Lina Guo, Xinxin Liao, Yafang Zhou, Weiwei Zhang, Lu Zhou, Xin Wang, Xixi Liu, Hui Liu, Tianyan Xu, Yuan Zhu, Qijie Yang, Xiaoli Hao, Yingzi Liu, Junling Wang, Jinchen Li, Bin Jiao & Lu Shen. (2021) The role of vascular dementia associated genes in patients with Alzheimer's disease: A large case–control study in the Chinese population. CNS Neuroscience & Therapeutics 27:12, pages 1531-1539.
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Wei Ling Lau, Mark Fisher, Evan Fletcher, Charles DeCarli, Hayden Troutt, María M. Corrada, Claudia Kawas & Annlia Paganini-Hill. (2021) Kidney Function Is Not Related to Brain Amyloid Burden on PET Imaging in The 90+ Study Cohort. Frontiers in Medicine 8.
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Jeneffar Roselin Christopher, Deepa PonnaiyanHarinath ParthasarathyAnupama Tadepalli. (2021) Association of CST3 Gene with Its Protein: Cystatin C in Health and Severe Periodontal Disease . Genetic Testing and Molecular Biomarkers 25:6, pages 405-410.
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Luminita Paraoan, Umar Sharif, Emil Carlsson, Wasu Supharattanasitthi, Nur Musfirah Mahmud, Tengku Ain Kamalden, Paul Hiscott, Malcolm Jackson & Ian Grierson. (2020) Secretory proteostasis of the retinal pigmented epithelium: Impairment links to age-related macular degeneration. Progress in Retinal and Eye Research 79, pages 100859.
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Yaling Jiang, Bin Jiao, Xinxin Liao, Xuewen Xiao, Xixi Liu & Lu Shen. (2020) Analyses Mutations in GSN, CST3, TTR, and ITM2B Genes in Chinese Patients With Alzheimer’s Disease. Frontiers in Aging Neuroscience 12.
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Lidia Ciccone, Chenghui Shi, Davide di Lorenzo, Anne-Cécile Van Baelen & Nicolo Tonali. (2020) The Positive Side of the Alzheimer’s Disease Amyloid Cross-Interactions: The Case of the Aβ 1-42 Peptide with Tau, TTR, CysC, and ApoA1. Molecules 25:10, pages 2439.
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Emil Carlsson, Wasu Supharattanasitthi, Malcolm Jackson & Luminita Paraoan. (2020) Increased Rate of Retinal Pigment Epithelial Cell Migration and Pro-Angiogenic Potential Ensuing From Reduced Cystatin C Expression. Investigative Opthalmology & Visual Science 61:2, pages 9.
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Zhizhen Cui, Guizhen Cao, Youyi Wang, Qinghua Ma, Congju Wang, Yong Xu, Hongpeng Sun & Yana Ma. (2020) Effects of Cystatin C on Cognitive Impairment in Older Chinese Adults. American Journal of Alzheimer's Disease & Other Dementiasr 35, pages 153331752096510.
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Qiong Zeng, Zhihua Huang, Liling Wei, Jingnian Fang & Kun Lin. (2019) Correlations of serum cystatin C level and gene polymorphism with vascular cognitive impairment after acute cerebral infarction. Neurological Sciences 40:5, pages 1049-1054.
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Wasu Supharattanasitthi, Emil Carlsson, Umar Sharif & Luminita Paraoan. (2019) CRISPR/Cas9-mediated one step bi-allelic change of genomic DNA in iPSCs and human RPE cells in vitro with dual antibiotic selection. Scientific Reports 9:1.
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Busra Gurel, Mehmet Cansev, Cansu Sevinc, Seda Kelestemur, Busra Ocalan, Aysen Cakir, Sami Aydin, Nevzat Kahveci, Mehmet Ozansoy, Ozlem Taskapilioglu, Ismail Hakki Ulus, Merve Karayel Başar, Betul Sahin, Mete Bora Tuzuner & Ahmet Tarik Baykal. (2018) Early Stage Alterations in CA1 Extracellular Region Proteins Indicate Dysregulation of IL6 and Iron Homeostasis in the 5XFAD Alzheimer’s Disease Mouse Model. Journal of Alzheimer's Disease 61:4, pages 1399-1410.
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Luisa Benussi, Giuliano Binetti & Roberta Ghidoni. (2017) Loss of Neuroprotective Factors in Neurodegenerative Dementias: The End or the Starting Point?. Frontiers in Neuroscience 11.
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Mohan Giri, Abhilasha Shah, Bibhuti Upreti & Jayanti Chamling Rai. (2017) Unraveling the genes implicated in Alzheimer's disease. Biomedical Reports 7:2, pages 105-114.
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Paul M. Mathews & Efrat Levy. (2016) Cystatin C in aging and in Alzheimer’s disease. Ageing Research Reviews 32, pages 38-50.
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Ricardo Sant'Anna, Susanna Navarro, Salvador Ventura, Luminita Paraoan & Debora Foguel. (2016) Amyloid properties of the leader peptide of variant B cystatin C: implications for Alzheimer and macular degeneration. FEBS Letters 590:5, pages 644-654.
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Annie Nguyen & John D. Hulleman. (2016) Evidence of Alternative Cystatin C Signal Sequence Cleavage Which Is Influenced by the A25T Polymorphism. PLOS ONE 11:2, pages e0147684.
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Qingli Xiao, Ping Yan, Xiucui Ma, Haiyan Liu, Ronaldo Perez, Alec Zhu, Ernesto Gonzales, Danielle L. Tripoli, Leah Czerniewski, Andrea Ballabio, John R. Cirrito, Abhinav Diwan & Jin-Moo Lee. (2015) Neuronal-Targeted TFEB Accelerates Lysosomal Degradation of APP, Reducing Aβ Generation and Amyloid Plaque Pathogenesis. The Journal of Neuroscience 35:35, pages 12137-12151.
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Joe M. Butler, Umar Sharif, Manir Ali, Martin McKibbin, Joseph P. Thompson, Richard Gale, Yit C. Yang, Chris Inglehearn & Luminita Paraoan. (2015) A missense variant in CST3 exerts a recessive effect on susceptibility to age-related macular degeneration resembling its association with Alzheimer’s disease. Human Genetics 134:7, pages 705-715.
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Kristine Yaffe, Manjula Kurella‐Tamura, Lynn Ackerson, Tina D. Hoang, Amanda H. Anderson, Mark Duckworth, Alan S. Go, Marie Krousel‐Wood, John W. Kusek, James P. Lash, Akinlolu Ojo, Nancy Robinson, Ashwini R. Sehgal, James H. Sondheimer, Susan Steigerwalt & Raymond R. Townsend. (2014) Higher Levels of Cystatin C Are Associated with Worse Cognitive Function in Older Adults with Chronic Kidney Disease: The Chronic Renal Insufficiency Cohort Cognitive Study. Journal of the American Geriatrics Society 62:9, pages 1623-1629.
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Yanling Hu, Amos C. Hung, Hao Cui, Edgar Dawkins, Marta Bolós, Lisa Foa, Kaylene M. Young & David H. Small. (2013) Role of Cystatin C in Amyloid Precursor Protein-induced Proliferation of Neural Stem/Progenitor Cells. Journal of Biological Chemistry 288:26, pages 18853-18862.
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