1,893
Views
58
CrossRef citations to date
0
Altmetric
Original Article

Potential role of gut microbiota and tissue barriers in Parkinson's disease and amyotrophic lateral sclerosis

Pages 771-776 | Received 20 Jun 2015, Accepted 16 Sep 2015, Published online: 16 Oct 2015

Keep up to date with the latest research on this topic with citation updates for this article.

Read on this site (3)

Yueqin Li, Yao Peng, Yingbin Shen, Yunzhen Zhang, Lianliang Liu & Xinquan Yang. (2023) Dietary polyphenols: regulate the advanced glycation end products-RAGE axis and the microbiota-gut-brain axis to prevent neurodegenerative diseases. Critical Reviews in Food Science and Nutrition 63:29, pages 9816-9842.
Read now
Alba Miranda-Ribera, Gloria Serena, Jundi Liu, Alessio Fasano, Marcy A. Kingsbury & Maria R. Fiorentino. (2022) The Zonulin-transgenic mouse displays behavioral alterations ameliorated via depletion of the gut microbiota. Tissue Barriers 10:3.
Read now

Articles from other publishers (55)

Christine Tara Peterson, Stanislav N. Iablokov, Dmitry A. Rodionov & Scott N. Peterson. (2023) Personalized Response of Parkinson’s Disease Gut Microbiota to Nootropic Medicinal Herbs In Vitro: A Proof of Concept. Microorganisms 11:8, pages 1979.
Crossref
Saima Khatoon, Nida Kalam, Summya Rashid & Gulnaz Bano. (2023) Effects of gut microbiota on neurodegenerative diseases. Frontiers in Aging Neuroscience 15.
Crossref
Hongmei Du, Zijun Huo, Yanchun Chen, Zhenhan Zhao, Fandi Meng, Xuemei Wang, Shiyue Liu, Haoyun Zhang, Fenghua Zhou, Jinmeng Liu, Lingyun Zhang, Shuanhu Zhou, Yingjun Guan & Xin Wang. (2023) Induced Pluripotent Stem Cells and Their Applications in Amyotrophic Lateral Sclerosis. Cells 12:6, pages 971.
Crossref
Sarika Yadav, Ashish Dwivedi, Anurag Tripathi & Amit Kumar Tripathi. (2022) Therapeutic potential of short-chain fatty acid production by gut microbiota in neurodegenerative disorders. Nutrition Research 106, pages 72-84.
Crossref
Hajra Ashraf, Paolo Solla & Leonardo Atonio Sechi. (2022) Current Advancement of Immunomodulatory Drugs as Potential Pharmacotherapies for Autoimmunity Based Neurological Diseases. Pharmaceuticals 15:9, pages 1077.
Crossref
Jiaqi Zeng, Xinchan Wang, Fei Pan & Zhiqi Mao. (2022) The relationship between Parkinson’s disease and gastrointestinal diseases. Frontiers in Aging Neuroscience 14.
Crossref
Wang Wang, Guoxue Zhu, Yuwen Wang, Wei Li, Shilin Yi, Kai Wang, Lu Fan, Juanjuan Tang & Ruini Chen. (2022) Multi-Omics Integration in Mice With Parkinson’s Disease and the Intervention Effect of Cyanidin-3-O-Glucoside. Frontiers in Aging Neuroscience 14.
Crossref
Sarah Martin, Carolina Battistini & Jun Sun. (2022) A Gut Feeling in Amyotrophic Lateral Sclerosis: Microbiome of Mice and Men. Frontiers in Cellular and Infection Microbiology 12.
Crossref
Belgin Sever, Halilibrahim Ciftci, Hasan DeMirci, Hilal Sever, Firdevs Ocak, Burak Yulug, Hiroshi Tateishi, Takahisa Tateishi, Masami Otsuka, Mikako Fujita & Ayşe Nazlı Başak. (2022) Comprehensive Research on Past and Future Therapeutic Strategies Devoted to Treatment of Amyotrophic Lateral Sclerosis. International Journal of Molecular Sciences 23:5, pages 2400.
Crossref
Emily A. Beck, Hope M. Healey, Clayton M. Small, Mark C. Currey, Thomas Desvignes, William A. Cresko & John H. Postlethwait. (2022) Advancing human disease research with fish evolutionary mutant models. Trends in Genetics 38:1, pages 22-44.
Crossref
Mohd F. Khan & Sugato Banerjee. 2022. Comprehensive Gut Microbiota. Comprehensive Gut Microbiota 175 180 .
Ankit Uniyal, Vineeta Tiwari, Mousmi Rani & Vinod Tiwari. (2021) Immune-microbiome interplay and its implications in neurodegenerative disorders. Metabolic Brain Disease 37:1, pages 17-37.
Crossref
Xiaoqing Li, Xin Feng, Zhongxiang Jiang & Zheng Jiang. (2021) Association of small intestinal bacterial overgrowth with Parkinson’s disease: a systematic review and meta-analysis. Gut Pathogens 13:1.
Crossref
Xin Fang, Fang-jun Li & Dao-jun Hong. (2021) Potential Role of Akkermansia muciniphila in Parkinson’s Disease and Other Neurological/Autoimmune Diseases. Current Medical Science 41:6, pages 1172-1177.
Crossref
Li Zhang, Huachong Xu, Ning Ding, Xue Li, Xiaoyin Chen & Zhuangfei Chen. (2021) Beneficial Effects on Brain Micro-Environment by Caloric Restriction in Alleviating Neurodegenerative Diseases and Brain Aging. Frontiers in Physiology 12.
Crossref
Nehal Yemula, Celina Dietrich, Vaclav Dostal & Michael Hornberger. (2021) Parkinson’s Disease and the Gut: Symptoms, Nutrition, and Microbiota. Journal of Parkinson's Disease 11:4, pages 1491-1505.
Crossref
Xueling Zhu, Bo Li, Pengcheng Lou, Tingting Dai, Yang Chen, Aoxiang Zhuge, Yin Yuan & Lanjuan Li. (2021) The Relationship Between the Gut Microbiome and Neurodegenerative Diseases. Neuroscience Bulletin 37:10, pages 1510-1522.
Crossref
Amr El-Sayed, Lotfi Aleya & Mohamed Kamel. (2021) Microbiota’s role in health and diseases. Environmental Science and Pollution Research 28:28, pages 36967-36983.
Crossref
Seok Jong Chung, John Hoon Rim, Dajeong Ji, Sangwon Lee, Han Soo Yoo, Jin Ho Jung, KyoungWon Baik, Yonghoon Choi, Byoung Seok Ye, Young H. Sohn, Mijin Yun, Sang-Guk Lee & Phil Hyu Lee. (2021) Gut microbiota-derived metabolite trimethylamine N-oxide as a biomarker in early Parkinson's disease. Nutrition 83, pages 111090.
Crossref
Julia Casani-Cubel, María Benlloch, Claudia Emmanuela Sanchis-Sanchis, Raquel Marin, Jose María Lajara-Romance & Jose Enrique de la Rubia Orti. (2021) The Impact of Microbiota on the Pathogenesis of Amyotrophic Lateral Sclerosis and the Possible Benefits of Polyphenols. An Overview. Metabolites 11:2, pages 120.
Crossref
EMILIA MANOLE, LAURA DUMITRESCU, CRISTINA NICULIȚE, BOGDAN OVIDIU POPESCU & LAURA CRISTINA CEAFALAN. (2021) Potential roles of functional bacterial amyloid proteins, bacterial biosurfactants and other putative gut microbiota products in the etiopathogeny of Parkinson’s Disease. BIOCELL 45:1, pages 1-16.
Crossref
Yusra Habib Khan, Aroosa Liaqat, Tauqeer Hussain Mallhi, Arooj Abid, Nasser Hadal Alotaibi & Amjad Khan. 2021. Environmental Contaminants and Neurological Disorders. Environmental Contaminants and Neurological Disorders 49 67 .
Seyed Aria Nejadghaderi, Ehsan Nazemalhosseini-Mojarad & Hamid Asadzadeh Aghdaei. (2020) Fecal microbiota transplantation for COVID-19; a potential emerging treatment strategy. Medical Hypotheses, pages 110476.
Crossref
Lu Chen, Yong Chen, Mingming Zhao, Lemin Zheng & Dongsheng Fan. (2020) Changes in the concentrations of trimethylamine N-oxide (TMAO) and its precursors in patients with amyotrophic lateral sclerosis. Scientific Reports 10:1.
Crossref
Weihao Li, Qinpin Zhao, Jiao Wang, Yajiang Wang & Tieqiao Wen. (2020) Dcf1 deletion presents alterations in gut microbiota of mice similar to Parkinson’s disease. Biochemical and Biophysical Research Communications 529:4, pages 1137-1144.
Crossref
Louis-Charles Béland, Andrea Markovinovic, Hrvoje Jakovac, Fabiola De Marchi, Ervina Bilic, Letizia Mazzini, Jasna Kriz & Ivana Munitic. (2020) Immunity in amyotrophic lateral sclerosis: blurred lines between excessive inflammation and inefficient immune responses. Brain Communications 2:2.
Crossref
B. Kuraszkiewicz, H. Goszczyńska, T. Podsiadły-Marczykowska, M. Piotrkiewicz, P. Andersen, M. Gromicho, J. Grosskreutz, M. Kuźma-Kozakiewicz, S. Petri, B. Stubbendorf, K. Szacka, H. Uysal & M. de Carvalho. (2020) Potential Preventive Strategies for Amyotrophic Lateral Sclerosis. Frontiers in Neuroscience 14.
Crossref
Mark Obrenovich, Hayden Jaworski, Tara Tadimalla, Adil Mistry, Lorraine Sykes, George Perry & Robert Bonomo. (2020) The Role of the Microbiota–Gut–Brain Axis and Antibiotics in ALS and Neurodegenerative Diseases. Microorganisms 8:5, pages 784.
Crossref
Emily A. Beck, Mark C. Currey, Clayton M. Small & William A. Cresko. (2020) QTL Mapping of Intestinal Neutrophil Variation in Threespine Stickleback Reveals Possible Gene Targets Connecting Intestinal Inflammation and Systemic Health. G3: Genes|Genomes|Genetics 10:2, pages 613-622.
Crossref
Bartłomiej Sankowski, Karolina Księżarczyk, Emilia Raćkowska, Stanisław Szlufik, Dariusz Koziorowski & Joanna Giebułtowicz. (2020) Higher cerebrospinal fluid to plasma ratio of p-cresol sulfate and indoxyl sulfate in patients with Parkinson’s disease. Clinica Chimica Acta 501, pages 165-173.
Crossref
Kaberi Chatterjee & Sugato Banerjee. 2020. The Microbiome. The Microbiome 111 122 .
Jessica Mandrioli, Amedeo Amedei, Giovanni Cammarota, Elena Niccolai, Elisabetta Zucchi, Roberto D'Amico, Federica Ricci, Gianluca Quaranta, Teresa Spanu & Luca Masucci. (2019) FETR-ALS Study Protocol: A Randomized Clinical Trial of Fecal Microbiota Transplantation in Amyotrophic Lateral Sclerosis. Frontiers in Neurology 10.
Crossref
Menizibeya O. Welcome. (2019) Gut Microbiota Disorder, Gut Epithelial and Blood–Brain Barrier Dysfunctions in Etiopathogenesis of Dementia: Molecular Mechanisms and Signaling Pathways. NeuroMolecular Medicine 21:3, pages 205-226.
Crossref
Suparna Roy Sarkar & Sugato Banerjee. (2019) Gut microbiota in neurodegenerative disorders. Journal of Neuroimmunology 328, pages 98-104.
Crossref
Mia Maguire & Greg Maguire. (2019) Gut dysbiosis, leaky gut, and intestinal epithelial proliferation in neurological disorders: towards the development of a new therapeutic using amino acids, prebiotics, probiotics, and postbiotics. Reviews in the Neurosciences 30:2, pages 179-201.
Crossref
Inez A. Flameling & Ger T. Rijkers. 2018. Gut Microbiota - Brain Axis. Gut Microbiota - Brain Axis.
Lindsay Joy Spielman, Deanna Lynn Gibson & Andis Klegeris. (2018) Unhealthy gut, unhealthy brain: The role of the intestinal microbiota in neurodegenerative diseases. Neurochemistry International 120, pages 149-163.
Crossref
Leo Pruimboom & Frits A.J. Muskiet. (2018) Intermittent living; the use of ancient challenges as a vaccine against the deleterious effects of modern life – A hypothesis. Medical Hypotheses 120, pages 28-42.
Crossref
Menizibeya O. Welcome. (2018) Current Perspectives and Mechanisms of Relationship between Intestinal Microbiota Dysfunction and Dementia: A Review. Dementia and Geriatric Cognitive Disorders Extra 8:3, pages 360-381.
Crossref
Michelle L. Wright, Christina Fournier, Madelyn C. Houser, Malú Tansey, Jonathan Glass & Vicki Stover Hertzberg. (2018) Potential Role of the Gut Microbiome in ALS: A Systematic Review. Biological Research For Nursing 20:5, pages 513-521.
Crossref
Aiqun Lin, Wenxia Zheng, Yan He, Wenli Tang, Xiaobo Wei, Rongni He, Wei Huang, Yuying Su, Yaowei Huang, Hongwei Zhou & Huifang Xie. (2018) Gut microbiota in patients with Parkinson's disease in southern China. Parkinsonism & Related Disorders 53, pages 82-88.
Crossref
Xin Fang. (2018) Impaired tissue barriers as potential therapeutic targets for Parkinson’s disease and amyotrophic lateral sclerosis. Metabolic Brain Disease 33:4, pages 1031-1043.
Crossref
Javier Riancho, Pilar Bosque-Varela, Sara Perez-Pereda, Mónica Povedano, Adolfo López de Munaín & Ana Santurtun. (2018) The increasing importance of environmental conditions in amyotrophic lateral sclerosis. International Journal of Biometeorology 62:8, pages 1361-1374.
Crossref
George Tetz & Victor Tetz. (2018) Bacteriophages as New Human Viral Pathogens. Microorganisms 6:2, pages 54.
Crossref
Sara Gerhardt & M. Mohajeri. (2018) Changes of Colonic Bacterial Composition in Parkinson’s Disease and Other Neurodegenerative Diseases. Nutrients 10:6, pages 708.
Crossref
Bozenna Kuraszkiewicz, Teresa Podsiadły-Marczykowska, Hanna Goszczyńska & Maria Piotrkiewicz. (2018) Are There Modifiable Environmental Factors Related to Amyotrophic Lateral Sclerosis?. Frontiers in Neurology 9.
Crossref
Pol Andrés-Benito, Jesús Moreno, Raúl Domínguez, Ester Aso, Mónica Povedano & Isidro Ferrer. (2017) Inflammatory Gene Expression in Whole Peripheral Blood at Early Stages of Sporadic Amyotrophic Lateral Sclerosis. Frontiers in Neurology 8.
Crossref
Ting Zhou, Tina Khorshid Ahmad, Kiana Gozda, Jessica Truong, Jiming Kong & Michael Namaka. (2017) Implications of white matter damage in amyotrophic lateral sclerosis. Molecular Medicine Reports 16:4, pages 4379-4392.
Crossref
David Brenner, Andreas Hiergeist, Carolin Adis, Benjamin Mayer, André Gessner, Albert C. Ludolph & Jochen H. Weishaupt. (2017) The fecal microbiome of ALS patients. Neurobiology of Aging.
Crossref
Daniel Erny, Anna Lena Hrabě de Angelis & Marco Prinz. (2017) Communicating systems in the body: how microbiota and microglia cooperate. Immunology 150:1, pages 7-15.
Crossref
Xin Fang, Xin Wang, Shaoguo Yang, Fanjing Meng, Xiaolei Wang, Hua Wei & Tingtao Chen. (2016) Evaluation of the Microbial Diversity in Amyotrophic Lateral Sclerosis Using High-Throughput Sequencing. Frontiers in Microbiology 7.
Crossref
Sofia D Karamintziou, Nick G Deligiannis, Brigitte Piallat, Mircea Polosan, Stephan Chabardès, Olivier David, Pantelis G Stathis, George A Tagaris, Efstathios J Boviatsis, Damianos E Sakas, Georgia E Polychronaki, George L Tsirogiannis & Konstantina S Nikita. (2016) Dominant efficiency of nonregular patterns of subthalamic nucleus deep brain stimulation for Parkinson’s disease and obsessive-compulsive disorder in a data-driven computational model. Journal of Neural Engineering 13:1, pages 016013.
Crossref
Zara A. Ioannides, Shyuan T. Ngo, Robert D. Henderson, Pamela A. McCombe & Frederik J. Steyn. (2016) Altered Metabolic Homeostasis in Amyotrophic Lateral Sclerosis: Mechanisms of Energy Imbalance and Contribution to Disease Progression. Neurodegenerative Diseases 16:5-6, pages 382-397.
Crossref
Laura de Magistris, Dario Siniscalco, Carmela Bravaccio & Carmelina Loguercio. 2016. Human Nutrition from the Gastroenterologist’s Perspective. Human Nutrition from the Gastroenterologist’s Perspective 49 65 .
Wang Wang, Guoxue Zhu, Yuwen Wang, Wei Li, Shilin Yi, Kai Wang, Lu Fan, Juanjuan Tang & Ruini Chen. (2022) Metabonomics Combined with 16S rRNA Gene Sequencing to Analyze the Changes of Gut Microbiota in Mice with Parkinson's Disease and the Intervention Effect of Cyanidin-3-O-Glucoside. SSRN Electronic Journal.
Crossref

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.