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Original Article

Clinical role and mechanisms of action of analgesic nitrous oxide

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Pages 55-62 | Received 15 Sep 1997, Published online: 07 Jul 2009

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Read on this site (2)

MARK A. GILLMAN, FREDERICK J. LICHTIGFELD & NADINE HARKER. (2006) PSYCHOTROPIC ANALGESIC NITROUS OXIDE FOR ACUTE COCAINE WITHDRAWAL IN MAN. International Journal of Neuroscience 116:7, pages 847-857.
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MARK A. GILLMAN, NADINE HARKER & FREDERICK J. LICHTIGFELD. (2006) COMBINED CANNABIS/METHAQUALONE WITHDRAWAL TREATED WITH PSYCHOTROPIC ANALGESIC NITROUS OXIDE. International Journal of Neuroscience 116:7, pages 859-869.
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Articles from other publishers (40)

Yuanyu Fu, Shuo Zhang, Zixuan Xu, Zijie Chen, Wanjun Zhang, Leilei Liu & Qi Wang. (2022) Impaired Synaptic Plasticity in the mPFC and Anxiety-Like Behaviour in Rats Following Repeated Nitrous Oxide Exposure. Iranian Journal of Science and Technology, Transactions A: Science 46:4, pages 1177-1185.
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Adam R Winstock & Jason A Ferris. (2019) Nitrous oxide causes peripheral neuropathy in a dose dependent manner among recreational users. Journal of Psychopharmacology 34:2, pages 229-236.
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Mark A. Gillman. (2019) Mini-Review: A Brief History of Nitrous Oxide (N2O) Use in Neuropsychiatry. Current Drug Research Reviews 11:1, pages 12-20.
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L-S Camilla d'Angelo, George Savulich & Barbara J Sahakian. (2017) Lifestyle use of drugs by healthy people for enhancing cognition, creativity, motivation and pleasure. British Journal of Pharmacology 174:19, pages 3257-3267.
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Rameet H. Singh, Lauren Thaxton, Shannon Carr, Lawrence Leeman, Emily Schneider & Eve Espey. (2016) A randomized controlled trial of nitrous oxide for intrauterine device insertion in nulliparous women. International Journal of Gynecology & Obstetrics 135:2, pages 145-148.
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Stephen J Kaar, Jason Ferris, Jon Waldron, Madonna Devaney, John Ramsey & Adam R Winstock. (2016) Up: The rise of nitrous oxide abuse. An international survey of contemporary nitrous oxide use. Journal of Psychopharmacology 30:4, pages 395-401.
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Laura Amato, Silvia Minozzi & Marina Davoli. (2011) Efficacy and safety of pharmacological interventions for the treatment of the Alcohol Withdrawal Syndrome. Cochrane Database of Systematic Reviews.
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Laura Amato, Silvia Minozzi & Marina Davoli. 1996. Cochrane Database of Systematic Reviews. Cochrane Database of Systematic Reviews.
Hyun-Jeong KwakYun Jeong ChaeSook Young LeeYoung Jun KimJong-Yeop Kim. (2010) Combination of nitrous oxide and lidocaine to prevent withdrawal after rocuronium in children. Korean Journal of Anesthesiology 58:5, pages 446.
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N. Benturquia, T. Le Marec, J.-M. Scherrmann & F. Noble. (2008) Effects of nitrous oxide on dopamine release in the rat nucleus accumbens and expectation of reward. Neuroscience 155:2, pages 341-344.
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N. Benturquia, S. Le Guen, C. Canestrelli, V. Lagente, G. Apiou, B.P. Roques & F. Noble. (2007) Specific blockade of morphine- and cocaine-induced reinforcing effects in conditioned place preference by nitrous oxide in mice. Neuroscience 149:3, pages 477-486.
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Mark Alfred Gillman, Frederick Lichtigfeld & Taryn Young. (2007) Psychotropic analgesic nitrous oxide for alcoholic withdrawal states. Cochrane Database of Systematic Reviews.
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Nancy J. Beckman, James P. Zacny & Diana J. Walker. (2006) Within-subject comparison of the subjective and psychomotor effects of a gaseous anesthetic and two volatile anesthetics in healthy volunteers. Drug and Alcohol Dependence 81:1, pages 89-95.
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Garrett Bird & Clifford Albert. (2005) Nitrous oxide as an adjunct in tumescent liposuction. Journal of Cosmetic Dermatology 4:4, pages 267-271.
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MA Gillman, FJ Lichtigfeld & TN Young. 1996. The Cochrane Database of Systematic Reviews. The Cochrane Database of Systematic Reviews.
A. Niazi, E. Galvin, I. Elsaigh, Z. Wahid, D. Harmon & I. Leonard. (2005) A combination of lidocaine and nitrous oxide in oxygen is more effective in preventing pain on propofol injection than either treatment alone. European Journal of Anaesthesiology 22:4, pages 299-302.
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Mark A. Gillman & Fred J. Lichtigfeld. (2004) Correct Use of Analgesic Nitrous Oxide for the Alcohol Withdrawal State Is Essential. Journal of Clinical Psychopharmacology 24:2, pages 238-239.
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D. Harmon, C. Rozario & D. Lowe. (2003) Nitrous oxide/oxygen mixture and the prevention of pain during injection of propofol. European Journal of Anaesthesiology 20:2, pages 158-161.
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A. Turan, B. Karamanlioğlu, D. Memiş & Z. Pamukçu. (2005) Alternative application site of transdermal nitroglycerin and the reduction of pain on propofol injection. European Journal of Anaesthesiology 20:2, pages 170-172.
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G. Kierzek, J. Audibert & J.-L. Pourriat. (2005) Anaphylaxis after rocuronium. European Journal of Anaesthesiology 20:2, pages 169-170.
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N. Anzawa, K. Hirota, M. Kitayama, T. Kushikata & A. Matsuki. (2005) Fentanyl-mediated reduction in the bispectral index and 95% spectral edge frequency is age-dependent. European Journal of Anaesthesiology 20:2, pages 167-169.
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J. J. Lehot, S. Helou & O. Bastien. (2005) Survey of antibiotic prophylaxis in cardiac surgery. European Journal of Anaesthesiology 20:2, pages 166-167.
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T. Villevieille, F. Mercier, P. E. Shannon, Y. Auroy & D. Benhamou. (2005) Efficacy of epidural analgesia during labour and delivery: a comparison between singleton vertex presentation, singleton breech presentation and twin pregnancies. European Journal of Anaesthesiology 20:2, pages 164-165.
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J. O'Rourke, C. Fahy & M. Donnelly. (2005) Subcutaneous emphysema at the site of central line placement due to the haematogenous spread of Clostridium septicum. European Journal of Anaesthesiology 20:2, pages 162-163.
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D. Harmon, C. Rozario & D. Lowe. (2005) Nitrous oxide/oxygen mixture and the prevention of pain during injection of propofol. European Journal of Anaesthesiology 20:2, pages 158-161.
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K. S. Thagaard, S. Steine & J. Raeder. (2005) Ondansetron disintegrating tablets of 8 mg twice a day for 3 days did not reduce the incidence of nausea or vomiting after laparoscopic surgery. European Journal of Anaesthesiology 20:2, pages 153-157.
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G. Lebuffe, T. Onimus & B. Vallet. (2005) Gastric mucosal-to-end-tidal PCO2 difference during major abdominal surgery: influence of the arterial-to-end-tidal PCO2 difference?. European Journal of Anaesthesiology 20:2, pages 147-152.
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H. Erolçay & L. Yüceyar. (2005) Intravenous patient-controlled analgesia after thoracotomy: a comparison of morphine with tramadol. European Journal of Anaesthesiology 20:2, pages 141-146.
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G. von Knobelsdorff, R. M. Höppner, P. H. Tonner, A. Paris, C. A. Nienaber, J. Scholz & J. Schulte am Esch. (2005) Induced arterial hypotension for interventional thoracic aortic stent-graft placement: impact on intracranial haemodynamics and cognitive function. European Journal of Anaesthesiology 20:2, pages 134-140.
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T. Bouillon, J. Bruhn, H. Roepcke & A. Hoeft. (2005) Opioid-induced respiratory depression is associated with increased tidal volume variability. European Journal of Anaesthesiology 20:2, pages 127-133.
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M. Westphal, H. Hohage, H. Buerkle, H. Van Aken, T. Ermert & and G. Brodner. (2005) Adsorption of sufentanil to epidural filters and catheters. European Journal of Anaesthesiology 20:2, pages 124-126.
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F. Karasawa, T. Okuda, M. Tsutsui, N. Matsuoka, S. Yamada, Y. Kawatani & T. Satoh. (2005) Dopamine stabilizes milrinone-induced changes in heart rate and arterial pressure during anaesthesia with isoflurane. European Journal of Anaesthesiology 20:2, pages 120-123.
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B. Heindl, F. Reichle & B. F. Becker. (2005) Sevoflurane but not isoflurane can reduce prostacyclin production of endothelial cells. European Journal of Anaesthesiology 20:2, pages 116-119.
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R. Tyther, J. O'Brien, J. Wang, H. P. Redmond & G. Shorten. (2005) Effect of sevoflurane on human neutrophil apoptosis. European Journal of Anaesthesiology 20:2, pages 111-115.
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K. Mikawa, H. Akamatsu, K. Nishina, M. Shiga, H. Obara & Y. Niwa. (2005) Effects of ropivacaine on human neutrophil function: comparison with bupivacaine and lidocaine. European Journal of Anaesthesiology 20:2, pages 104-110.
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R. Bogdanski, M. Blobner, H. Fink & E. Kochs. (2005) Effects of xenon on mesenteric blood flow. European Journal of Anaesthesiology 20:2, pages 98-103.
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C. D. Hanning, A. Blokland, M. Johnson & E. K. Perry. (2005) Effects of repeated anaesthesia on central cholinergic function in the rat cerebral cortex. European Journal of Anaesthesiology 20:2, pages 93-97.
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O. A. P. Santanen, N. Svartling, J. Haasio & M. P. J. Paloheimo. (2005) Neural nets and prediction of the recovery rate from neuromuscular block. European Journal of Anaesthesiology 20:2, pages 87-92.
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Mark A. Gillman & F.J. Lichtigfeld. (2000) Analgesic nitrous oxide: An opioid treatment formigraine. The American Journal of Emergency Medicine 18:4, pages 501.
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