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Scandinavian Journal of Clinical and Laboratory Investigation Volume 70, 2010 - Issue 8
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Research Article

Determination of cyclosporine, tacrolimus, sirolimus and everolimus by liquid chromatography coupled to electrospray ionization and tandem mass spectrometry: Assessment of matrix effects and assay performance

Nils T. Vethe Department of Medical Biochemistry, Oslo University Hospital, NorwayCorrespondence[email protected]
,
Laila C. Gjerdalen Department of Medical Biochemistry, Oslo University Hospital, Norway
&
Stein Bergan Department of Pharmacology, Oslo University Hospital, Norway; School of Pharmacy, University of Oslo, Norway
Pages 583-591 | Received 05 Jul 2010, Accepted 01 Oct 2010, Published online: 01 Nov 2010

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Karen Cristina dos Santos, Leidiana Rocha dos Reis, Camila Fernanda Rodero, Rafael Miguel Sábio, Alberto Gomes Tavares Junior, Maria Palmira Daflon Gremião & Marlus Chorilli. (2022) Bioproperties, Nanostructured System and Analytical and Bioanalytical Methods for Determination of Rapamycin: A Review. Critical Reviews in Analytical Chemistry 52:5, pages 897-905.
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Esperanza F. Hermida-Cadahia & J. Carlos Tutor. (2012) Determination of everolimus in blood samples from kidney and liver transplant recipients using the sirolimus chemiluminescence magnetic microparticle immunoassay (CMIA) on the Architect-i1000® System. Scandinavian Journal of Clinical and Laboratory Investigation 72:2, pages 180-183.
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Articles from other publishers (20)

Karen Cristina dos Santos, Leidiana Rocha dos Reis, Camila Fernanda Rodero, Rafael Miguel Sábio, Alberto Gomes Tavares Junior, Maria Palmira Daflon Gremião & Marlus Chorilli. (2023) Bioproperties, Nanostructured System and Analytical and Bioanalytical Methods for Determination of Rapamycin: A Review. Critical Reviews in Analytical Chemistry, pages 1-9.
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Cristiano Ialongo, Annamaria D’alessandro, Maria Sapio, Antonio Angeloni & Ottavia Porzio. (2023) Evaluation of the interchangeability between the new fully-automated affinity chrome-mediated immunoassay (ACMIA) and the Quantitative Microsphere System (QMS) with a CE-IVD-certified LC-MS/MS assay for therapeutic drug monitoring of everolimus after solid organ transplantation. Clinical Chemistry and Laboratory Medicine (CCLM) 61:2, pages 245-250.
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Kensuke Shigeta, Masafumi Kikuchi, Masaki Tanaka, Shinya Takasaki, Hisashi Oishi, Tetsu Sado, Yasushi Matsuda, Masafumi Noda, Yoshinori Okada, Nariyasu Mano & Hiroaki Yamaguchi. (2020) Development of a precise quantitative method for monitoring sirolimus in whole blood using LC/ESI–MS/MS. Biomedical Chromatography 34:8.
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Mercè BrunetTeun van GelderAnders ÅsbergVincent HaufroidDennis A. HesselinkLoralie LangmanFlorian LemaitrePierre MarquetChristoph SegerMaria ShipkovaAlexander VinksPierre WallemacqEberhard WielandJean Baptiste WoillardMarkus J. BartenKlemens BuddeHelena ColomMaja-Theresa DieterlenLaure ElensKamisha L. Johnson-DavisPaweł K. KunickiIain MacPheeSatohiro MasudaBinu S. MathewOlga MillánTomoyuki MizunoDirk-Jan A. R. MoesCaroline MonchaudOfelia NocetiTomasz PawinskiNicolas PicardRon van SchaikClaudia SommererNils Tore VetheBrenda de Winter, Uwe ChristiansStein Bergan. (2019) Therapeutic Drug Monitoring of Tacrolimus-Personalized Therapy: Second Consensus Report. Therapeutic Drug Monitoring 41:3, pages 261-307.
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Magdalena Bodnar-Broniarczyk, Tomasz Pawiński & Paweł K. Kunicki. (2019) Isotope–labeled versus analog internal standard in LC–MS/MS method for tacrolimus determination in human whole blood samples – A compensation of matrix effects. Journal of Chromatography B 1104, pages 220-227.
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Ida Robertsen, Jean Debord, Anders Åsberg, Pierre Marquet & Jean-Baptiste Woillard. (2018) A Limited Sampling Strategy to Estimate Exposure of Everolimus in Whole Blood and Peripheral Blood Mononuclear Cells in Renal Transplant Recipients Using Population Pharmacokinetic Modeling and Bayesian Estimators. Clinical Pharmacokinetics 57:11, pages 1459-1469.
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Shenghui Mei, Jiaqing Wang, Di Chen, Leting Zhu, Ming Zhao, Xiaoxin Tian, Xin Hu & Zhigang Zhao. (2018) Simultaneous determination of cyclosporine and tacrolimus in human whole blood by ultra-high performance liquid chromatography tandem mass spectrometry and comparison with a chemiluminescence microparticle immunoassay. Journal of Chromatography B 1087-1088, pages 36-42.
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Shenghui Mei, Jiaqing WangDi ChenLeting ZhuMing ZhaoXin HuLi Yang & Zhigang Zhao. (2018) Ultra–High Performance Liquid Chromatography Tandem Mass Spectrometry for Cyclosporine Analysis in Human Whole Blood and Comparison With an Antibody-Conjugated Magnetic Immunoassay. Therapeutic Drug Monitoring 40:1, pages 69-75.
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Shery Jacob & Anroop B. Nair. (2017) A review on therapeutic drug monitoring of the mTOR class of immunosuppressants: everolimus and sirolimus. Drugs & Therapy Perspectives 33:6, pages 290-301.
Crossref
Heike Bittersohl & Werner Steimer. 2016. Personalized Immunosuppression in Transplantation. Personalized Immunosuppression in Transplantation 199 226 .
Ida Robertsen, Nils Tore Vethe, Karsten Midtvedt, Pål Falck, Hege Christensen & Anders Åsberg. (2015) Closer to the Site of Action. Therapeutic Drug Monitoring 37:5, pages 675-680.
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Elisabet Størset, Nick Holford, Stefanie Hennig, Troels K. Bergmann, Stein Bergan, Sara Bremer, Anders Åsberg, Karsten Midtvedt & Christine E. Staatz. (2014) Improved prediction of tacrolimus concentrations early after kidney transplantation using theory‐based pharmacokinetic modelling. British Journal of Clinical Pharmacology 78:3, pages 509-523.
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Ida Robertsen, Anders Åsberg, Tone Granseth, Nils Tore Vethe, Fatemeh Akhlaghi, Mwlod Ghareeb, Espen Molden, Morten Reier-Nilsen, Hallvard Holdaas & Karsten Midtvedt. (2014) More Potent Lipid-Lowering Effect by Rosuvastatin Compared With Fluvastatin in Everolimus-Treated Renal Transplant Recipients. Transplantation 97:12, pages 1266-1271.
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Gilberto AlvesMárcio Rodrigues, Ana Fortuna, Amílcar Falcão & João Queiroz. (2013) A critical review of microextraction by packed sorbent as a sample preparation approach in drug bioanalysis. Bioanalysis 5:11, pages 1409-1442.
Crossref
Courtney Heideloff, Drew Payto & Sihe Wang. (2013) Comparison of a Stable Isotope-Labeled and an Analog Internal Standard for the Quantification of Everolimus by a Liquid Chromatography–Tandem Mass Spectrometry Method. Therapeutic Drug Monitoring 35:2, pages 246-250.
Crossref
Amitava Dasgupta. (2012) Impact of Interferences Including Metabolite Crossreactivity on Therapeutic Drug Monitoring Results. Therapeutic Drug Monitoring 34:5, pages 496-506.
Crossref
Isabelle Laverdière, Patrick Caron, Félix Couture, Éric Lévesque & Chantal Guillemette. (2012) A liquid chromatography–tandem mass spectrometry (LC–MS/MS) method for monitoring drug exposure in hematopoietic stem cell transplant recipients. Journal of Chromatography B 885-886, pages 131-137.
Crossref
Pierre-Olivier Hétu, Robert Robitaille & Bernard Vinet. (2012) Successful and cost-efficient replacement of immunoassays by tandem mass spectrometry for the quantification of immunosuppressants in the clinical laboratory. Journal of Chromatography B 883-884, pages 95-101.
Crossref
Joanne E. Adaway & Brian G. Keevil. (2012) Therapeutic drug monitoring and LC–MS/MS. Journal of Chromatography B 883-884, pages 33-49.
Crossref
Misuk Ji, Sollip Kim, Hee-Jung Chung, Woochang Lee, Sail Chun & Won-Ki Min. (2011) Evaluation of the MassTrak Immunosuppressant XE Kit for the determination of everolimus and cyclosporin A in human whole blood employing isotopically labeled internal standards. Clinical Chemistry and Laboratory Medicine (CCLM) 49:12.
Crossref

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