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Review Article

Lipoprotein(a) and risk of myocardial infarction – genetic epidemiologic evidence of causality

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Pages 87-93 | Published online: 13 Jan 2011

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Elham Rahmani, Mehri Jamilian, Mansooreh Samimi, Maryam Zarezade Mehrizi, Esmat Aghadavod, Elmira Akbari, Omid Reza Tamtaji & Zatollah Asemi. (2018) The effects of coenzyme Q10 supplementation on gene expression related to insulin, lipid and inflammation in patients with polycystic ovary syndrome. Gynecological Endocrinology 34:3, pages 217-222.
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Vybhav Jetty, Charles J Glueck, Kevin Lee, Naila Goldenberg, Marloe Prince, Ashwin Kumar, Michael Goldenberg, Ishan Anand & Ping Wang. (2017) Eligibility for alirocumab or evolocumab treatment in 1090 hypercholesterolemic patients referred to a regional cholesterol treatment center with LDL cholesterol ≥70 mg/dL despite maximal-tolerated LDL-cholesterol-lowering therapy. Vascular Health and Risk Management 13, pages 247-253.
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April Rees, Zoe Edwards-I-Coll, Oliver Richards, Molly E Raikes, Roberto Angelini & Catherine A Thornton. (2023) The dynamic inflammatory profile of pregnancy can be monitored using a novel lipid-based mass spectrometry technique. Molecular Omics 19:4, pages 340-350.
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Karam Kostner & Gerhard M. Kostner. 2023. Lipoproteins in Diabetes Mellitus. Lipoproteins in Diabetes Mellitus 247 274 .
Claudia Lamina. (2022) Mendelian Randomization: Principles and its usage in Lp(a) research. Atherosclerosis 349, pages 36-41.
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Victor França, Érica Ivana Lázaro Gomes, Edite Vieira Silva de Campos, Vanessa Helena de Souza Zago, Valéria Sutti Nunes & Eliana Cotta de Faria. (2022) Relationship between lipoprotein (a) and subclinical carotid atherosclerosis in asymptomatic individuals. Clinics 77, pages 100107.
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Jenny Sandmark, Anna Tigerström, Tomas Akerud, Magnus Althage, Thomas Antonsson, Stefan Blaho, Cristian Bodin, Jonas Boström, Yantao Chen, Anders Dahlén, Per-Olof Eriksson, Emma Evertsson, Tomas Fex, Ola Fjellström, David Gustafsson, Margareta Herslöf, Ryan Hicks, Emelie Jarkvist, Carina Johansson, Inge Kalies, Birgitta Karlsson Svalstedt, Fredrik Kartberg, Anne Legnehed, Sofia Martinsson, Andreas Moberg, Marianne Ridderström, Birgitta Rosengren, Alan Sabirsh, Anders Thelin, Johanna Vinblad, Annika U. Wellner, Bingze Xu, Ann-Margret Östlund-Lindqvist & Wolfgang Knecht. (2020) Identification and analyses of inhibitors targeting apolipoprotein(a) kringle domains KIV-7, KIV-10, and KV provide insight into kringle domain function. Journal of Biological Chemistry 295:15, pages 5136-5151.
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U. Julius, S. Tselmin, U. Schatz, S. Fischer & S. R. Bornstein. (2019) Lipoprotein(a)—an interdisciplinary challenge. Clinical Research in Cardiology Supplements 14:S1, pages 20-27.
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Enas A. Enas, Basil Varkey, T.S. Dharmarajan, Guillaume Pare & Vinay K. Bahl. (2019) Lipoprotein(a): An independent, genetic, and causal factor for cardiovascular disease and acute myocardial infarction. Indian Heart Journal 71:2, pages 99-112.
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Latha Palaniappan, Arun Garg, Enas Enas, Henrietta Lewis, Sehrish Bari, Martha Gulati, Cristina Flores, Ashish Mathur, Cesar Molina, Jagat Narula, Shahid Rahman, Jennifer Leng & Francesca Gany. (2018) South Asian Cardiovascular Disease & Cancer Risk: Genetics & Pathophysiology. Journal of Community Health 43:6, pages 1100-1114.
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Ali Akbar Hashemzadeh, Nikoo Nasoohi, Fariba Raygan, Esmat Aghadavod, Elmira Akbari, Mohsen Taghizadeh, Mohammad Reza Memarzadeh & Zatollah Asemi. (2017) Flaxseed Oil Supplementation Improve Gene Expression Levels of PPAR-γ, LP(a), IL-1 and TNF-α in Type 2 Diabetic Patients with Coronary Heart Disease. Lipids 52:11, pages 907-915.
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Khadijeh Nasri, Sedigheh Hantoushzadeh, Esmat Aghadavod, Mohsen Taghizadeh & Zatollah Asemi. (2017) The Effects of Omega-3 Fatty Acids Supplementation on Gene Expression Involved in the Insulin and Lipid Signaling Pathway in Patients with Polycystic Ovary Syndrome. Hormone and Metabolic Research 49:06, pages 446-451.
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Elham Rahmani, Mansooreh Samimi, Faraneh Afshar Ebrahimi, Fatemeh Foroozanfard, Shahnaz Ahmadi, Maryam Rahimi, Mehri Jamilian, Esmat Aghadavod, Fereshteh Bahmani, Mohsen Taghizadeh, Mohammad Reza Memarzadeh & Zatollah Asemi. (2017) The effects of omega-3 fatty acids and vitamin E co-supplementation on gene expression of lipoprotein(a) and oxidized low-density lipoprotein, lipid profiles and biomarkers of oxidative stress in patients with polycystic ovary syndrome. Molecular and Cellular Endocrinology 439, pages 247-255.
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Yaoyu Zou, Tinglu Ning, Juan Shi, Maopei Chen, Lin Ding, Ya Huang, Sophie Kauderer, Min Xu, Bin Cui, Yufang Bi, Simin Liu, Jie Hong, Ruixin Liu, Guang Ning & Jiqiu Wang. (2017) Association of a gain-of-function variant in LGR4 with central obesity . Obesity 25:1, pages 252-260.
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Vesela D. Tomova, Tihomir R. Rashev & Milena A. Atanasova. (2016) Genetic Polymorphisms, Plasma Levels of Lipoprotein (A) and its Possible Links with Degenerative Aortic Stenosis. Journal of Biomedical and Clinical Research 9:1, pages 59-64.
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Henning Jansen, Wolfgang Lieb & Heribert Schunkert. (2016) Mendelian Randomization for the Identification of Causal Pathways in Atherosclerotic Vascular Disease. Cardiovascular Drugs and Therapy 30:1, pages 41-49.
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Nguyen T Nguyen, Merry L Lindsey & Yu-Fang Jin. (2015) Systems analysis of gene ontology and biological pathways involved in post-myocardial infarction responses. BMC Genomics 16:S7.
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S. Tselmin, G. M?ller, E. Gelgaft, S. Fischer & U. Julius. (2015) An elevated lipoprotein(a) plasma level as a cardiovascular risk factor. Atherosclerosis Supplements 18, pages 257-262.
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Pamela Smith. 2015. Nutritional and Integrative Strategies in Cardiovascular Medicine. Nutritional and Integrative Strategies in Cardiovascular Medicine 337 368 .
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Martha Rodríguez-Moran & Fernando Guerrero-Romero. (2014) Low birthweight and elevated levels of lipoprotein(a) in prepubertal children. Journal of Paediatrics and Child Health 50:8, pages 610-614.
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Marianne Månsson, Inge Kalies, Göran Bergström, Caroline Schmidt, Anne Legnehed, Lillemor Mattsson Hultén, Lena Amrot-Fors, David Gustafsson & Wolfgang Knecht. (2014) Lp(a) is not associated with diabetes but affects fibrinolysis and clot structure ex vivo. Scientific Reports 4:1.
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Zheng YePhilip C. HaycockDeepti GurdasaniCristina PomillaS. Matthijs Boekholdt, Sotirios Tsimikas, Kay-Tee KhawNicholas J. WarehamManjinder S. SandhuNita G. Forouhi. (2014) The Association Between Circulating Lipoprotein(a) and Type 2 Diabetes: Is It Causal?. Diabetes 63:1, pages 332-342.
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Alicia J. Jenkins, Karam M. Kostner & Gerhard M. Kostner. 2014. Lipoproteins in Diabetes Mellitus. Lipoproteins in Diabetes Mellitus 141 155 .
Mohamed M. Shabban, Mohamed A. Metawie, Khaled A. Atwa & Amr E. Elsaman. (2013) Atherogenic profile of mild pre-eclampsia. Evidence Based Womenʼs Health Journal 3:4, pages 196-200.
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Wen-Liang Song & Garret A. FitzGerald. (2013) Niacin, an old drug with a new twist. Journal of Lipid Research 54:10, pages 2586-2594.
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Eveline Oestreicher Stock & Rita Redberg. (2012) Cardiovascular Disease in Women. Current Problems in Cardiology 37:11, pages 450-526.
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B. F. Sode, M. Dahl & B. G. Nordestgaard. (2011) Myocardial infarction and other co-morbidities in patients with chronic obstructive pulmonary disease: a Danish Nationwide Study of 7.4 million individuals. European Heart Journal 32:19, pages 2365-2375.
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