555
Views
55
CrossRef citations to date
0
Altmetric
Research Article

Imbalance of regulatory T cells to Th17 cells in IgA nephropathy

, , , , &
Pages 221-229 | Received 18 Jul 2011, Accepted 13 Dec 2011, Published online: 25 Jan 2012

Keep up to date with the latest research on this topic with citation updates for this article.

Read on this site (3)

Noha A Hassuna, Mohamed Mansour, Tarek I Ahmed, Essam A Hassan, Mohamed M Hefzy, Wael M Abd Elghani & Enas M Hefzy. (2020) Chronic Hepatitis C Infection Has No Effect on Peripheral CD4+CD25+ Tregulatory Cells in Patients with End-Stage Renal Disease. Immunological Investigations 49:4, pages 477-488.
Read now
Lixi Li, Ran Luo, Yi Yang, Yichun Cheng, Shuwang Ge & Gang Xu. (2020) Tamibarotene inhibit the accumulation of fibrocyte and alleviate renal fibrosis by IL-17A. Renal Failure 42:1, pages 1173-1183.
Read now
Jia-Ru Lin, Ji Wen, Hui Zhang, Li Wang, Fang-Fang Gou, Man Yang & Jun-Ming Fan. (2018) Interleukin-17 promotes the production of underglycosylated IgA1 in DAKIKI cells. Renal Failure 40:1, pages 60-67.
Read now

Articles from other publishers (52)

Micaela Gentile, Luis Sanchez-Russo, Leonardo V Riella, Alberto Verlato, Joaquin Manrique, Simona Granata, Enrico Fiaccadori, Francesco Pesce, Gianluigi Zaza & Paolo Cravedi. (2023) Immune abnormalities in IgA nephropathy. Clinical Kidney Journal 16:7, pages 1059-1070.
Crossref
Sijia Ma, Bin Yang, Mingming Zhao, Peng Li, Jiao Fan, Meiying Chang, Zhiyu Pan, Ziyan Zhang, Shunxuan Xue & Yu Zhang. (2023) Effects of modified Huangqi Chifeng decoction on the IL-17 signaling pathway in an IgA nephropathy rat model. Journal of Ethnopharmacology 307, pages 116220.
Crossref
Stephanie U-Shane Huang, Oneli Kulatunge & Kim Maree O’Sullivan. (2023) Deciphering the Genetic Code of Autoimmune Kidney Diseases. Genes 14:5, pages 1028.
Crossref
Yujuan Li, Huixia Liu, Hao Yan & Jing Xiong. (2023) Research advances on targeted-Treg therapies on immune-mediated kidney diseases. Autoimmunity Reviews 22:2, pages 103257.
Crossref
Alexandra Linke, Gisa Tiegs & Katrin Neumann. (2022) Pathogenic T-Cell Responses in Immune-Mediated Glomerulonephritis. Cells 11:10, pages 1625.
Crossref
Marie Robert, Pierre Miossec & Arnaud Hot. (2022) The Th17 Pathway in Vascular Inflammation: Culprit or Consort?. Frontiers in Immunology 13.
Crossref
Hongyan Liao, Zhuochun Huang, Junlong Zhang & Bin Yang. (2021) Association of genetic polymorphisms in IL-23R and IL-17A with the susceptibility to IgA nephropathy in a Chinese Han population. Genes & Immunity 23:1, pages 33-41.
Crossref
Serdar E Bulun, Sule Yildiz, Mazhar Adli & Jian-Jun Wei. (2021) Adenomyosis pathogenesis: insights from next-generation sequencing. Human Reproduction Update 27:6, pages 1086-1097.
Crossref
Jiachuan Xiong, Yu Qiao, Zhikai Yu, Yinghui Huang, Ke Yang, Ting He & Jinghong Zhao. (2021) T-Lymphocyte Subsets Alteration, Infection and Renal Outcome in Advanced Chronic Kidney Disease. Frontiers in Medicine 8.
Crossref
Feliciano Chanana Paquissi & Hugo Abensur. (2021) The Th17/IL-17 Axis and Kidney Diseases, With Focus on Lupus Nephritis. Frontiers in Medicine 8.
Crossref
Katrin Neumann & Gisa Tiegs. (2021) Immune regulation in renal inflammation. Cell and Tissue Research 385:2, pages 305-322.
Crossref
Licia Peruzzi, Rosanna Coppo, Enrico Cocchi, Elisa Loiacono, Massimilano Bergallo, Monica Bodria, Luca Vergano, Alexandra Krutova, Maria Luisa Russo, Alessandro Amore, Sigrid Lundberg, Dita Maixerova, Vladimir Tesar, Agnieszka Perkowska-Ptasińska, Magdalena Durlik, Dimitris Goumenos, Marios Papasotiriou, Kresimir Galesic, Luka Toric, Aikaterini Papagianni, Maria Stangou, Malgorzata Mizerska-Wasiak, Loreto Gesualdo, Eustacchio Montemurno, Luisa Benozzi, Stefano Cusinato, Tomasz Hryszko, Marian Klinger, Dorota Kamińska & Magdalena Krajewska. (2021) The switch from proteasome to immunoproteasome is increased in circulating cells of patients with fast progressive immunoglobulin A nephropathy and associated with defective CD46 expression. Nephrology Dialysis Transplantation 36:8, pages 1389-1398.
Crossref
Georgios Vlachopanos, Argyrios Georgalis, Pinelopi Korkolopoulou, Efstratios Patsouris & Harikleia Gakiopoulou. (2021) Immunohistochemical Expression of FOXP3+ Regulatory T Cells in Proteinuric Primary Glomerulopathies. International Journal of Nephrology 2021, pages 1-10.
Crossref
Yue-miao Zhang, Xing-zi Liu, Xu-jie Zhou, Li-jun Liu, Su-fang Shi, Ping Hou, Ji-cheng Lv & Hong Zhang. (2021) A Functional Variant rs3093023 in CCR6 Is Associated With IgA Nephropathy by Regulating Th17 Cells in a North Han Chinese Population. Frontiers in Immunology 12.
Crossref
Johanna Rehnberg, Adina Symreng, Jonas F. Ludvigsson & Louise Emilsson. (2021) Inflammatory Bowel Disease Is More Common in Patients with IgA Nephropathy and Predicts Progression of ESKD: A Swedish Population-Based Cohort Study. Journal of the American Society of Nephrology 32:2, pages 411-423.
Crossref
Min Wei, Sijun Meng, Sufang Shi, Lijun Liu, Xujie Zhou, Jicheng Lv, Li Zhu & Hong Zhang. (2021) Monozygotic Twins Discordant for Immunoglobulin A Nephropathy Display Differences in DNA Methylation and Gene Expression. Kidney Diseases 7:3, pages 200-209.
Crossref
Rakel Nurmi, Jussi Pohjonen, Martti Metso, Ilkka Pörsti, Onni Niemelä, Heini Huhtala, Jukka Mustonen, Katri Kaukinen & Satu Mäkelä. (2021) Prevalence of Inflammatory Bowel Disease and Celiac Disease in Patients with IgA Nephropathy over Time. Nephron 145:1, pages 78-84.
Crossref
Yuka Segawa, Ryo Ishida, Fuminao Kanehisa, Kunihiro Nakai, Mari Morimoto, Masafumi Seno, Mayuka Nakayama, Tetsuro Kusaba, Norito Katoh & Keiichi Tamagaki. (2020) IgA nephropathy in a patient receiving infliximab for generalized pustular psoriasis. BMC Nephrology 21:1.
Crossref
Rosanna Coppo & Thomas Robert. (2020) IgA nephropathy in children and in adults: two separate entities or the same disease?. Journal of Nephrology 33:6, pages 1219-1229.
Crossref
Qi Han, Jianyu Tong, Qi Sun, Xiaojie Teng, Hongfu Zhang & Xiaohua Teng. (2020) The involvement of miR-6615-5p/Smad7 axis and immune imbalance in ammonia-caused inflammatory injury via NF-κB pathway in broiler kidneys. Poultry Science 99:11, pages 5378-5388.
Crossref
Tianyu Hu, Min Wang, Wei Chen, Jinghong Zhao & Jiachuan Xiong. (2020) The clinical characteristic and outcome of skin and soft tissue infection in immunosuppressive patients with nephrotic syndrome. Clinical and Experimental Nephrology 24:9, pages 779-788.
Crossref
Yue-Yu Gu, Xu-Sheng Liu, Xiao-Ru Huang, Xue-Qing Yu & Hui-Yao Lan. (2020) TGF-β in renal fibrosis: triumphs and challenges. Future Medicinal Chemistry 12:9, pages 853-866.
Crossref
Yuyan Tang, Haidong He, Pin Hu & Xudong Xu. (2020) T lymphocytes in IgA nephropathy (Review). Experimental and Therapeutic Medicine.
Crossref
Yali Niu, Bo Zhou, Chunxiao Wan, Rui wu, Heying Sun & Danqing Lu. (2020) Down-regulation of miR-181a promotes microglial M1 polarization through increasing expression of NDRG2. Aging Pathobiology and Therapeutics 2:1, pages 52-57.
Crossref
Sheng Chang & Xiao-Kang Li. (2020) The Role of Immune Modulation in Pathogenesis of IgA Nephropathy. Frontiers in Medicine 7.
Crossref
Hamid Mortazavi, Mohammad Sadegh Soltani‐Zangbar, Shadi Eghbal‐Fard, Amir Mehdizadeh, Amin Kamrani, Forough Chakeri‐Khiavi, Hossein Samadi Kafil, Farhad Jadidi‐Niaragh, Shahrzad Rahimifar, Hamid Tayebi Khosroshahi & Mehdi Yousefi. (2019) Cytokine profile, Treg/Th17 cell frequency changes during different posttransplantational time points in patients undergoing renal transplantation. Journal of Cellular Physiology 234:11, pages 20935-20943.
Crossref
Jin Chen, Hui Liu, Liyan Li, Honglei Wang, Yi Li, Yihao Wang, Kai Ding, Shanfeng Hao, Yuanyuan Shao, Lijuan Li, Jia Song, Guojin Wang, Zonghong Shao & Rong Fu. (2019) Abnormal numbers of CD4+ T lymphocytes and abnormal expression of CD4+ T lymphocyte‑secreted cytokines in patients with immune‑related haemocytopenia. Molecular Medicine Reports.
Crossref
Rosanna Coppo, Licia Peruzzi, Elisa Loiacono, Massimilano Bergallo, Alexandra Krutova, Maria Luisa Russo, Enrico Cocchi, Alessandro Amore, Sigrid Lundberg, Dita Maixnerova, Vladimir Tesar, Agnieszka Perkowska-Ptasińska, Magdalena Durlik, Dimitris Goumenos, Miltiadis Gerolymos, Kresimir Galesic, Luka Toric, Aikaterini Papagianni, Maria Stangou, Malgorzata Mizerska-Wasia Membek, Loreto Gesualdo, Eustacchio Montemurno, Luisa Benozzi, Stefano Cusinato, Tomasz Hryszko, Marian Klinger, Dorota Kamińska & Magdalena Krajewska. (2019) Defective gene expression of the membrane complement inhibitor CD46 in patients with progressive immunoglobulin A nephropathy. Nephrology Dialysis Transplantation 34:4, pages 587-596.
Crossref
Jakub Ruszkowski, Katarzyna A. Lisowska, Małgorzata Pindel, Zbigniew Heleniak, Alicja Dębska-Ślizień & Jacek M. Witkowski. (2018) T cells in IgA nephropathy: role in pathogenesis, clinical significance and potential therapeutic target. Clinical and Experimental Nephrology 23:3, pages 291-303.
Crossref
Partha S. Biswas. (2018) IL-17 in Renal Immunity and Autoimmunity. The Journal of Immunology 201:11, pages 3153-3159.
Crossref
Monica Suet Ying Ng, Leo Francis, Elango Pillai & Andrew John Mallett. (2018) Paraneoplastic immunoglobulin A nephropathy and associated focal segmental glomerulosclerosis in asymptomatic low volume B-cell lymphoma – a case report. BMC Nephrology 19:1.
Crossref
Yuyan Tang, Haidong He, Weiqian Sun, Pin Hu, Xia Chen & Xudong Xu. (2018) Corticosteroid therapy in IgA nephropathy with minimal proteinuria and high renal pathological score: A single‑center cohort study. Molecular Medicine Reports.
Crossref
Takahiro Yamauchi, Shigehiro Doi, Ayumu Nakashima, Toshiki Doi, Eisei Sohara, Shinichi Uchida & Takao Masaki. (2018) Na + -Cl − cotransporter-mediated chloride uptake contributes to hypertension and renal damage in aldosterone-infused rats . American Journal of Physiology-Renal Physiology 315:2, pages F300-F312.
Crossref
Lu Gan, Mengyuan Zhu, Xiaozhao Li, Chen Chen, Ting Meng, Jiaxi Pu, Huiming Luo, Fengmin Shao & Qiaoling Zhou. (2018) Tonsillitis exacerbates renal injury in IgA nephropathy through promoting Th22 cells chemotaxis. International Urology and Nephrology 50:7, pages 1285-1292.
Crossref
Maliha A Alikhan, Megan Huynh, A Richard Kitching & Joshua D Ooi. (2018) Regulatory T cells in renal disease. Clinical & Translational Immunology 7:1, pages e1004.
Crossref
Baohui Yang, Xiongjun Tan, Xiao Xiong, Daoqi Wu, Gaofu Zhang, Mo Wang, Shifang Dong, Wei Liu, Haiping Yang & Qiu Li. (2016) Effect of CD40/CD40L signaling on IL-10-producing regulatory B cells in Chinese children with Henoch-Schönlein purpura nephritis. Immunologic Research 65:3, pages 592-604.
Crossref
Lichuan Yang, XiaoYan Zhang, Wei Peng, Mian Wei & Wei Qin. (2016) MicroRNA-155-induced T lymphocyte subgroup drifting in IgA nephropathy. International Urology and Nephrology 49:2, pages 353-361.
Crossref
Min Hu, Yuan Min Wang, Yiping Wang, Geoff Y. Zhang, Guoping Zheng, Shounan Yi, Philip J. O’Connell, David C.H. Harris & Stephen I. Alexander. (2016) Regulatory T cells in kidney disease and transplantation. Kidney International 90:3, pages 502-514.
Crossref
Stephen R. Holdsworth, Poh-Yi Gan & A. Richard Kitching. (2016) Biologics for the treatment of autoimmune renal diseases. Nature Reviews Nephrology 12:4, pages 217-231.
Crossref
Ying Zhang, Jin Wang, Qiao-dan Zhou, Cong-hui Zhang, Qing Li, Shuai Huang, Juan Zhan, Kun Wang, Yan-yan Liu & Gang Xu. (2016) Peroxisome proliferator-activated receptor-γ agonist pioglitazone fails to attenuate renal fibrosis caused by unilateral ureteral obstruction in mice. Journal of Huazhong University of Science and Technology [Medical Sciences] 36:1, pages 41-47.
Crossref
Radmila Micanovic, Brahmananda R. Chitteti, Pierre C. Dagher, Edward F. Srour, Shehnaz Khan, Takashi Hato, Allison Lyle, Yan Tong, Xue-Ru Wu & Tarek M. El-Achkar. (2015) Tamm-Horsfall Protein Regulates Granulopoiesis and Systemic Neutrophil Homeostasis. Journal of the American Society of Nephrology 26:9, pages 2172-2182.
Crossref
Bora Gülhan, Diclehan Orhan, Gülsev Kale, Nesrin Besbas & Seza Özen. (2015) Studying cytokines of T helper cells in the kidney disease of IgA vasculitis (Henoch–Schönlein purpura). Pediatric Nephrology 30:8, pages 1269-1277.
Crossref
Yoon Seok Roh, Surim Park, Chae Woong Lim & Bumseok Kim. (2014) Depletion of Foxp3+ Regulatory T Cells Promotes Profibrogenic Milieu of Cholestasis-Induced Liver Injury. Digestive Diseases and Sciences 60:7, pages 2009-2018.
Crossref
Ting Meng, Xiaozhao Li, Xiang Ao, Yong Zhong, Rong Tang, Weisheng Peng, Jinghua Yang, Mingxiang Zou & Qiaoling Zhou. (2014) Hemolytic Streptococcus May Exacerbate Kidney Damage in IgA Nephropathy through CCL20 Response to the Effect of Th17 Cells. PLoS ONE 9:9, pages e108723.
Crossref
Maria Elena Donadio, Elisa Loiacono, Licia Peruzzi, Alessandro Amore, Roberta Camilla, Federica Chiale, Luca Vergano, Alberto Boido, Margherita Conrieri, Manuela Bianciotto, Francesca Maria Bosetti & Rosanna Coppo. (2014) Toll-like receptors, immunoproteasome and regulatory T cells in children with Henoch–Schönlein purpura and primary IgA nephropathy. Pediatric Nephrology 29:9, pages 1545-1551.
Crossref
Mutlu Uysal Yazici, Diclehan Orhan, Gulsev Kale, Nesrin Besbas & Seza Ozen. (2014) Studying IFN-gamma, IL-17 and FOXP3 in pediatric lupus nephritis. Pediatric Nephrology 29:5, pages 853-862.
Crossref
Jing Zhang, Yan Li, Kai Shan, Lulu Wang, Wen Qiu, Yanlai Lu, Dan Zhao, Ganqian Zhu, Fengxia He & Yingwei Wang. (2013) Sublytic C5b‐9 induces IL‐6 and TGF‐β1 production by glomerular mesangial cells in rat Thy‐1 nephritis through p300‐mediated C/EBPβ acetylation. The FASEB Journal 28:3, pages 1511-1525.
Crossref
Ana Cristina Simões e Silva, André Barreto Pereira, Mauro Martins Teixeira & Antônio Lúcio Teixeira. (2014) Chemokines as Potential Markers in Pediatric Renal Diseases. Disease Markers 2014, pages 1-9.
Crossref
Zhiguo Peng, Jun Tian, Xianquan Cui, Wanhua Xian, Huaibin Sun, Engang Li, Lina Geng, Luwei Zhang & Peng Zhao. (2013) Increased number of Th22 cells and correlation with Th17 cells in peripheral blood of patients with IgA nephropathy. Human Immunology 74:12, pages 1586-1591.
Crossref
R. Coppo. (2013) Is a legacy effect possible in IgA nephropathy?. Nephrology Dialysis Transplantation 28:7, pages 1657-1662.
Crossref
Monika Ryba-Stanisławowska, Maria Skrzypkowska, Jolanta Myśliwska & Małgorzata Myśliwiec. (2013) The Serum IL-6 Profile and Treg/Th17 Peripheral Cell Populations in Patients with Type 1 Diabetes. Mediators of Inflammation 2013, pages 1-7.
Crossref
Jimmy Z. Shen & Morag J. Young. (2012) Corticosteroids, Heart Failure, and Hypertension: A Role for Immune Cells?. Endocrinology 153:12, pages 5692-5700.
Crossref

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.