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Scandinavian Journal of Clinical and Laboratory Investigation Volume 22, 1968 - Issue 1
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Original Article

Plasma Prothrombin during Treatment with Dicumarol

I. Immunochemical Determination of its Concentration in Plasma

J. E. Niléhn Department of Clinical Chemistry, (University of Lund) Malmö General Hospital, Malmö, Sweden
&
P. O. Ganrot Department of Clinical Chemistry, (University of Lund) Malmö General Hospital, Malmö, Sweden
Pages 17-22 | Received 12 Apr 1968, Accepted 22 May 1968, Published online: 08 Jul 2009

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B. G. Johansson, Co. Kindmark, E. Y. Trell & F. A. Wollheim. (1972) Sequential Changes of Plasma Proteins after Myocardial Infarction. Scandinavian Journal of Clinical and Laboratory Investigation 29:sup124, pages 117-126.
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P. O. Ganrot. (1972) Variation of the Concentrations of some Plasma Proteins in normal Adults, in Pregnant Women and in Newborns. Scandinavian Journal of Clinical and Laboratory Investigation 29:sup124, pages 83-88.
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P. O. Ganrot. (1972) How Apparently Identical Antisera Can Give Apparently Different Results. Scandinavian Journal of Clinical and Laboratory Investigation 29:sup124, pages 67-70.
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P. O. Ganrot & J-E. Niléhn. (1969) Prothrombin Fragmentation During Coagulation of Whole Blood and Plasma. Scandinavian Journal of Clinical and Laboratory Investigation 24:1, pages 15-21.
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P. O. Ganrot & J.-E. Niléhn. (1968) Plasma Prothrombin during Treatment with Dicumarol. Scandinavian Journal of Clinical and Laboratory Investigation 22:1, pages 28-28.
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Sten Müllertz. (1968) Approaches to the Molecular Chemistry of Coagulation and Fibrinolysis. Scandinavian Journal of Clinical and Laboratory Investigation 22:1, pages 1-3.
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Articles from other publishers (42)

Yang Yang, Guangbing Li, Ziwen Lu, Yong Liu, Junjie Kong & Jun Liu. (2021) Progression of Prothrombin Induced by Vitamin K Absence-II in Hepatocellular Carcinoma. Frontiers in Oncology 11.
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Ulla K.E. Hedner. 2017. Treating Life-Threatening Bleedings. Treating Life-Threatening Bleedings 15 25 .
Hao Xing, Cunling Yan, Liming Cheng, Nianyue Wang, Shuyang Dai, Jianyong Yuan, Wenfeng Lu, Zhouchong Wang, Jun Han, Yijie Zheng & Tian Yang. (2016) Clinical application of protein induced by vitamin K antagonist-II as a biomarker in hepatocellular carcinoma. Tumor Biology 37:12, pages 15447-15456.
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Russell F. Doolittle. (2016) Some Important Milestones in the Field of Blood Clotting. Journal of Innate Immunity 8:1, pages 23-29.
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Keunhee Kang, Ji Hoon Kim, Seong Hee Kang, Beom Jae Lee, Yeon Seok Seo, Hyung Joon Yim, Jong Eun Yeon, Jong-Jae Park, Jae Seon Kim, Young-Tae Bak & Kwan Soo Byun. (2015) The Influence of Alcoholic Liver Disease on Serum PIVKA-II Levels in Patients without Hepatocellular Carcinoma. Gut and Liver 9:2, pages 224-230.
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J. STENFLO. (2006) From γ‐carboxy‐glutamate to protein C. Journal of Thrombosis and Haemostasis 4:12, pages 2521-2526.
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Yvonne Stirling, D. J. Howarth, R. Stockley, R. Bland, C. M. Towler & S. M. Harding. (2008) Comparison of the bioavailabilities and anticoagulant activities of two warfarin formulations. British Journal of Haematology 51:1, pages 37-46.
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Bruce Furie, Rita A. Blanchard, David J. Robison, Mindy M. Tai & Barbara C. Furie. 1982. Immunochemical Techniques Part D: Selected Immunoassays. Immunochemical Techniques Part D: Selected Immunoassays 60 83 .
Rita A. Blanchard, Barbara C. Furie, Maria Jorgensen, Steven F. Kruger & Bruce Furie. (1981) Acquired Vitamin K-Dependent Carboxylation Deficiency in Liver Disease. New England Journal of Medicine 305:5, pages 242-248.
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B. Connor Johnson. (1981) Post-translational carboxylation of preprothrombin. Molecular and Cellular Biochemistry 38:1, pages 77-121.
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B. Connor Johnson. 1982. The Biological Effects of Glutamic Acid and Its Derivatives. The Biological Effects of Glutamic Acid and Its Derivatives 77 121 .
D. H. Parry, J. C. Giddings & A. L. Bloom. (2008) Familial Haemostatic Defect Associated with Reduced Prothrombin Consumption. British Journal of Haematology 44:2, pages 323-334.
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B. Connor Johnson. 1980. Vitamins and Coenzymes Part F. Vitamins and Coenzymes Part F 165 180 .
R.A. Blanchard, B.C. Furie & B. Furie. (1979) Antibodies specific for bovine abnormal (des-gamma-carboxy-)prothrombin.. Journal of Biological Chemistry 254:24, pages 12513-12520.
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Robert E. Olson & John W. Suttie. 1978. 59 108 .
Johan Stenflo. 1978. Advances in Enzymology and Related Areas of Molecular Biology. Advances in Enzymology and Related Areas of Molecular Biology 1 31 .
Johan Stenflo. (1977) Vitamin K, Prothrombin and γ-Carboxyglutamic Acid. New England Journal of Medicine 296:11, pages 624-626.
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Murray Nussbaum & Christos B. Moschos. (1976) Anticoagulants and Anticoagulation. Medical Clinics of North America 60:5, pages 855-869.
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J Stenflo. (1976) A new vitamin K-dependent protein. Purification from bovine plasma and preliminary characterization.. Journal of Biological Chemistry 251:2, pages 355-363.
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P Fernlund, J Stenflo, P Roepstorff & J Thomsen. (1975) Vitamin K and the biosynthesis of prothrombin. V. Gamma-carboxyglutamic acids, the vitamin K-dependent structures in prothrombin.. Journal of Biological Chemistry 250:15, pages 6125-6133.
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J.W. Suttie. 1975. 463 481 .
Reidar Wallin & Hans Prydz. (1975) Purification from bovine blood of the warfarin-induced precursor of prothrombin. Biochemical and Biophysical Research Communications 62:2, pages 398-406.
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Milica Brozovic & D. J. Howarth. 1975. Prothrombin and Related Coagulation Factors. Prothrombin and Related Coagulation Factors 252 263 .
Doris Mesache, Marie-Claude Guillin, Catherine Boyer & Nicole Cesbron. 1975. Prothrombin and Related Coagulation Factors. Prothrombin and Related Coagulation Factors 159 166 .
Johan Stesflo. 1975. Prothrombin and Related Coagulation Factors. Prothrombin and Related Coagulation Factors 152 158 .
N. Heimburger & H. Karges. 1975. Anwendung immunologischer Methoden. Anwendung immunologischer Methoden 251 271 .
Johan Stenflo. (1974) Vitamin K and the Biosynthesis of Prothrombin. Journal of Biological Chemistry 249:17, pages 5527-5535.
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D. J. Howarth, Mllica Brozović, Yvonne Stirling & Margaret Reed. (2009) Factor VII during Warfarin Treatment. Scandinavian Journal of Haematology 12:5, pages 346-354.
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H. G. Schwick, H. Trobisch & N. Heimburger. (1974) Importanza e limiti delle tecniche immunologiche nella diagnostica delle coagulopatie. La Ricerca in Clinica e in Laboratorio 4:1-4, pages 617-637.
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Milica Brozović, Linda Gurd & David John Howarth. (1973) Consumption of abnormal prothrombin in the presence of different types of thromboplastin. Thrombosis Research 2:6, pages 557-566.
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M. Brozović & L. J. Gurd. (2008) Prothrombin during Warfarin Treatment. British Journal of Haematology 24:5, pages 579-588.
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K. N. Jeejeebhoy, A. Bruce-Robertson, J. Ho & U. Sodtke. 1973. Ciba Foundation Symposium 9 - Protein Turnover. Ciba Foundation Symposium 9 - Protein Turnover 217 247 .
Gary L. Nelsestuen & John W. Suttie. (1972) The Purification and Properties of an Abnormal Prothrombin Protein Produced by Dicumarol-treated Cows. Journal of Biological Chemistry 247:24, pages 8176-8182.
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Johan Stenflo & Per-Olov Ganrot. (1972) Vitamin K and the Biosynthesis of Prothrombin. Journal of Biological Chemistry 247:24, pages 8160-8166.
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R. A. SLAASTAD & H. C. GODAL. (2009) Discrepancy between Thrombotest and Normotest - an Indicator of Disseminated Intravascular Coagulation (DIC)?. Scandinavian Journal of Haematology 9:1-6, pages 411-416.
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R. A. SLAASTAD & M. JEREMIC. (2009) Discrepancy between Normotest and Thrombotest during Thromboplastin Induced Intravascular Coagulation in Rabbits. Scandinavian Journal of Haematology 9:1-6, pages 403-410.
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Gabor Rez & Hans Prydz. (1971) The mode of action of warfarin. An intracellular precursor for factor VII in rat liver. Biochimica et Biophysica Acta (BBA) - General Subjects 244:2, pages 495-499.
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O.P. Malhotra & John R. Carter. (1971) Isolation and Purification of Prothrombin from Dicumarolized Steers. Journal of Biological Chemistry 246:8, pages 2665-2671.
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H. Prydz & G. Gaudernack. (1971) Studies on the biosynthesis of factor VII (proconvertin) the mode of action of warfarin. Biochimica et Biophysica Acta (BBA) - General Subjects 230:2, pages 373-380.
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Norbert Heimburger & Heiner Trobisch. (2003) Blood Coagulation and Fibrinolysis. Angewandte Chemie International Edition in English 10:2, pages 85-97.
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Norbert Heimburger & Heiner Trobisch. (2006) Blutgerinnung und Fibrinolyse. Angewandte Chemie 83:3, pages 89-102.
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Staffan Magnusson. 1970. Proteolytic Enzymes. Proteolytic Enzymes 157 184 .

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