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Scandinavian Journal of Clinical and Laboratory Investigation Volume 30, 1972 - Issue 2
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Original Article

Intracellular pH of the Brain in Arterial Hypoxemia, Evaluated with the CO2Method and from the Creatine Phosphokinase Equilibrium

V. Macmillan Brain Research Laboratory, E-Blocket, University Hospital, Lund, Sweden
&
B. K. Siesjö Brain Research Laboratory, E-Blocket, University Hospital, Lund, Sweden
Pages 117-125 | Received 28 Mar 1972, Accepted 14 Jul 1972, Published online: 08 Jul 2009

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David Laman, James Theodore & Eugene D. Robin. (1981) Regulation of Intracytoplasmic pH and “Apparent” Intracellular pH in Alveolar Macrophages. Experimental Lung Research 2:2, pages 141-153.
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V. Macmillan & B. K. Siesjö. (1972) The Effect of Hypercapnia upon the Energy Metabolism of the Brain during Arterial Hypoxemia. Scandinavian Journal of Clinical and Laboratory Investigation 30:3, pages 237-244.
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V. Macmillan & B. K. Siesjö. (1972) Brain Energy Metabolism in Hypoxemia. Scandinavian Journal of Clinical and Laboratory Investigation 30:2, pages 127-136.
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Articles from other publishers (33)

Susan J. Vannucci, Lisa B. Willing, Shozo GotoNabil J. AlkayedRobert M. Brucklacher, Teresa L. Wood, Javad Towfighi, Patricia D. HurnIan A. Simpson. (2016) Experimental Stroke in the Female Diabetic, db/db , Mouse . Journal of Cerebral Blood Flow & Metabolism 21:1, pages 52-60.
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Tim S. Whittingham, Hussein Assaf, Warren R. Selman, Robert A. Ratcheson & W. David Lust. (1992) Glutamate-induced energetic stress in hippocampal slices: Evidence against NMDA and glutamate uptake as mediators. Metabolic Brain Disease 7:2, pages 77-92.
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Kenneth R. WagnerMarla KleinholzGabrielle M. de Courten-MyersRonald E. Myers. (2016) Hyperglycemic versus Normoglycemic Stroke: Topography of Brain Metabolites, Intracellular pH, and Infarct Size. Journal of Cerebral Blood Flow & Metabolism 12:2, pages 213-222.
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F. A. M. de Azeredo. (1991) Transient changes in energy metabolites and intracellular pH during spreading depression in the chick retina. Metabolic Brain Disease 6:2, pages 75-82.
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R. Christian CrumrineJoseph C. LaManna. (2016) Regional Cerebral Metabolites, Blood Flow, Plasma Volume, and Mean Transit Time in Total Cerebral Ischemia in the Rat. Journal of Cerebral Blood Flow & Metabolism 11:2, pages 272-282.
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R. Christian Crumrine & Joseph C. LaManna. (2006) Protein Kinase C Activity in Rat Brain Cortex. Journal of Neurochemistry 55:3, pages 826-831.
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M. Shimoda, Sh. Yamada, I. Yamamoto, R. Tsugane & O. Sato. (1989) Time course of csf lactate level in subarachnoid haemorrhage correlation with clinical grading and prognosis. Acta Neurochirurgica 99:3-4, pages 127-134.
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Tim S. Whittingham, Eduardo Warman, Hussein Assaf, Thomas J. Sick & Joseph C. LaManna. (1989) Manipulating the intracellular environment of hippocampal slices: pH and high-energy phosphates. Journal of Neuroscience Methods 28:1-2, pages 83-91.
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Thomas J. Sick, Tim S. Whittingham & Joseph C. LaManna. (1989) Determination of intracellular pH in the in vitro hippocampal slice preparation by transillumination spectrophotometry of Neutral red. Journal of Neuroscience Methods 27:1, pages 25-34.
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John V. Weil. 2011. Comprehensive Physiology. Comprehensive Physiology 703 727 .
Bo K. Siesjö & Martin Ingvar. 2011. Comprehensive Physiology. Comprehensive Physiology 141 161 .
Shinichi Yoshida, Masuhiro Ikeda, Raul Busto, Mercedes Santiso, Elena Martinez & Myron D. Ginsberg. (2006) Cerebral Phosphoinositide, Triacylglycerol, and Energy Metabolism in Reversible Ischemia: Origin and Fate of Free Fatty Acids. Journal of Neurochemistry 47:3, pages 744-757.
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D. B. KintnerJ. L. KaoR. D. WoodsonD. D. Gilboe. (2016) Evaluation of Artificial Plasma for Maintaining the Isolated Canine Brain. Journal of Cerebral Blood Flow & Metabolism 6:4, pages 455-462.
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Shinichi YoshidaRaul BustoElena MartinezPeritz ScheinbergMyron D. Ginsberg. (2016) Regional Brain Energy Metabolism after Complete versus Incomplete Ischemia in the Rat in the Absence of Severe Lactic Acidosis. Journal of Cerebral Blood Flow & Metabolism 5:4, pages 490-501.
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Tim S. Whittingham, W. David Lust, Dimitri A. Christakis & Janet V. Passonneau. (1984) Metabolic Stability of Hippocampal Slice Preparations During Prolonged Incubation. Journal of Neurochemistry 43:3, pages 689-696.
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Peter Lipton & Tim S. Whittingham. 1984. Brain Slices. Brain Slices 113 153 .
TAKEFUMI SAKABE, NILS DAHLGREN, ARVID CARLSSON & BO K. SIESJÖ. (2008) Effect of diazepam on cerebral monoamine synthesis during hypoxia and hypercapnia in the rat. Acta Physiologica Scandinavica 115:1, pages 57-65.
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D.A. Pelligrino, T.I. Musch & J.A. Dempsey. (1981) Interregional differences in brain intracellular pH and water compartmentation during acute normoxic and hypoxic hypocapnia in the anesthetized dog. Brain Research 214:2, pages 387-404.
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Jens Astrup, Dieter Heuser, Niels A. Lassen, Bengt Nilsson, Karin Norberg & Bo K. Siesjd. 1978. Ciba Foundation Symposium 56 - Cerebral Vascular Smooth Muscle and Its Control. Ciba Foundation Symposium 56 - Cerebral Vascular Smooth Muscle and Its Control 313 337 .
Kyuya Kogure, Peritz Scheinberg, Yoichi Utsunomiya, Hidemi Kishikawa & Raul Busto. (2004) Sequential cerebral biochemical and physiological events in controlled hypoxemia. Annals of Neurology 2:4, pages 304-310.
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V. MacMillan. (1977) Cerebral carbohydrate metabolism during acute carbon monoxide intoxication. Brain Research 121:2, pages 271-286.
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V. S. Sergeeva, �. M. Kogan & Yu. M. Levin. (1976) A rapid test of liver morphology and function. Bulletin of Experimental Biology and Medicine 82:5, pages 1758-1760.
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William Meier-Ruge. (1975) Experimental pathology and pharmacology in brain research and aging. Life Sciences 17:11, pages 1627-1635.
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Halldór Jóhannsson & Bo. K. Siesjö. (2008) Brain Energy Metabolism in Anesthetized Rats in Acute Anemia. Acta Physiologica Scandinavica 93:4, pages 515-524.
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K. Norberg & B.K. Siejö. (1975) Cerebral metabolism in hypoxic hypoxia. II. Citric acid cycle intermediates and associated amino acids. Brain Research 86:1, pages 45-54.
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K. Norberg & B.K. Siesjö. (1975) Cerebral metabolism in hypoxic hypoxia. I. Pattern of activation of glycolysis: a re-evaluation. Brain Research 86:1, pages 31-44.
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M. E. Raichle. 1975. Ciba Foundation Symposium 34 - Outcome of Severe Damage to the CNS. Ciba Foundation Symposium 34 - Outcome of Severe Damage to the CNS 85 96 .
Joseph T. Davidson, Brian J. Whipp, Karlman Wasserman, Sankar N. Koyal & Robert Lugliani. (1974) Role of the Carotid Bodies in Breath-Holding. New England Journal of Medicine 290:15, pages 819-822.
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T. Holmin & B. K. Siesjö. (1974) INFLUENCE OF HYPOXIA ON CEREBRAL ENERGY STATE IN RATS WITH PORTA-CAVAL ANASTOMOSIS. Journal of Neurochemistry 22:3, pages 413-417.
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James N. Davis, A. Carlsson, Vernon MacMillan & Bo K. Siesjö. (1973) Brain Tryptophan Hydroxylation: Dependence on Arterial Oxygen Tension. Science 182:4107, pages 72-74.
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Bo Eklöf, Vernon MacMillan & Bo K. Siesjö. (2008) The Effect of Hypercapnic Acidosis upon the Energy Metabolism of the Brain in Arterial Hypotension Caused by Bleeding. Acta Physiologica Scandinavica 87:1, pages 1-14.
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Bo Eklöf & Bo K. Siesjö. (2008) The Effect of Bilateral Carotid Artery Ligation upon Acid‐Base Parameters and Substrate Levels in the Rat Brain . Acta Physiologica Scandinavica 86:4, pages 528-538.
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Bo Eklöf, Vernon Macmillan & Bo K. Siesjö. (2008) Cerebral Energy State and Cerebral Venous Po 2 in Experimental Hypotension Caused by Bleeding . Acta Physiologica Scandinavica 86:4, pages 515-527.
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