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Scandinavian Journal of Clinical and Laboratory Investigation Volume 30, 1972 - Issue 3
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Original Article

The Normal Region –- a Multivariate Problem

P. Winkel Dept. of Clinical Chemistry A, Rigshospitalet, Copenhagen, Denmark
&
J. Lyngbye Dept. of Clinical Chemistry A, Rigshospitalet, Copenhagen, Denmark
Pages 339-344 | Received 24 Apr 1972, Accepted 25 Aug 1972, Published online: 08 Jul 2009

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Per Winkel. (1994) Multivariate analysis and expert systems. Scandinavian Journal of Clinical and Laboratory Investigation 54:sup219, pages 12-24.
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Bertil Kågedal, Lasse Larsson, Anders Norr & Göran Toss. (1982) Trivariate evaluation of a thyroid hormone panel in clinical practice compared with multiple univariate evaluation. Scandinavian Journal of Clinical and Laboratory Investigation 42:2, pages 177-180.
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E. Jacquelin Dietz & TimothyJ. Killeen. (1981) A Nonparametric Multivariate Test for Monotone Trend with Pharmaceutical Applications. Journal of the American Statistical Association 76:373, pages 169-174.
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Helge E. Solberg. (1978) Discriminant Analysis. CRC Critical Reviews in Clinical Laboratory Sciences 9:3, pages 209-242.
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Adam Cawley, Bethany Keen, Kathy Tou, Madysen Elbourne & John Keledjian. (2022) Biomarker ratios. Drug Testing and Analysis 14:5, pages 983-990.
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Elaine Holmes, Ian D. Wilson & John C. Lindon. 2019. The Handbook of Metabolic Phenotyping. The Handbook of Metabolic Phenotyping 1 51 .
Gary L. Horowitz. 2012. Tietz Textbook of Clinical Chemistry and Molecular Diagnostics. Tietz Textbook of Clinical Chemistry and Molecular Diagnostics 95 118 .
Rainer Haeckel, Werner Wosniok & Farhad Arzideh. (2007) A plea for intra-laboratory reference limits. Part 1. General considerations and concepts for determination. Clinical Chemical Laboratory Medicine 45:8.
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Donald C Trost. (2006) Multivariate Probability-Based Detection of Drug-Induced Hepatic Signals. Toxicological Reviews 25:1, pages 37-54.
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George G. Klee. (2004) Clinical interpretation of reference intervals and reference limits. A plea for assay harmonization. Clinical Chemistry and Laboratory Medicine (CCLM) 42:7.
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James C. Boyd. (2004) Reference regions of two or more dimensions. Clinical Chemistry and Laboratory Medicine (CCLM) 42:7.
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Eileen M WrightPatrick Royston. (2016) Calculating reference intervals for laboratory measurements. Statistical Methods in Medical Research 8:2, pages 93-112.
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Marcel Hekking, Jan Lindemans & Edzard S. Gelsema. (1997) A computer program for constructing multivariate reference models. Computer Methods and Programs in Biomedicine 53:3, pages 191-200.
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Helge Erik Solberg & Ralph Gräsbeck. 1989. Advances in Clinical Chemistry Volume 27. Advances in Clinical Chemistry Volume 27 1 79 .
Ida H. Stamhuis, P.Dick Bezemer & D. Joop Kuik. (1988) Evaluation of univariate ranges with a multivariate standard. Journal of Clinical Epidemiology 41:4, pages 359-366.
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D. Coomans, I. Broeckaert, M.P. Derde, A. Tassin, D.L. Massart & S. Wold. (1984) Use of a microcomputer for the definition of multivariate confidence regions in medical diagnosis based on clinical laboratory profiles. Computers and Biomedical Research 17:1, pages 1-14.
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W. Rehpenning, K. Harm, J.-D. Ringe, G. H. Bützow & K. D. Voigt. (1984) Quasi-verteilungsfreie multivariate Beurteilung klinisch-chemischer Kenngrößen mit Hilfe der X-Transformation von van der Waerden. Clinical Chemistry and Laboratory Medicine 22:4.
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D.L. Massart. (1983) Observer: Multi- or uni-variate reference regions?. TrAC Trends in Analytical Chemistry 2:6, pages V-VI.
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Wolfgang RehpenningWolfgang Rehpenning. 1983. Multivariate Datenbeurteilung. Multivariate Datenbeurteilung 87 89 .
W. Rehpenning & K.-D. Voigt. 1983. Methoden der Statistik und Informatik in Epidemiologie und Diagnostik. Methoden der Statistik und Informatik in Epidemiologie und Diagnostik 389 399 .
Ralph R. Grams. (1979) A proposal for laboratory data reporting. Journal of Medical Systems 3:3-4, pages 193-198.
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K. Harm, W. Rehpenning, Astrid Domesle & K. D. Voigt. (1979) Falsch positive Werte bei der Vielfachanalyse: Eine Erhebung an Referenz- und Patientenkollektiven. Clinical Chemistry and Laboratory Medicine 17:8.
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Gitten Cederblad, Bertil Kågedal, Anders Norr, Bo Sörbo, Lennart Tegler & Ove Wigertz. 1979. Medical Informatics Berlin 1979. Medical Informatics Berlin 1979 650 657 .
Robert B. McComb, George N. BowersJr.Jr. & Solomon PosenRobert B. McComb, George N. BowersJr.Jr. & Solomon Posen. 1979. Alkaline Phosphatase. Alkaline Phosphatase 525 786 .

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