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Original Article

Unsaturated and cobalamin saturated transcobalamin I and II in normal human plasma

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Pages 723-728 | Received 06 May 1977, Accepted 13 Aug 1977, Published online: 08 Jul 2009

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Omar Abuyaman, Ma’mon M. Hatmal, Nawal Hijjawi, Ahmad A. Deeb, Mohammad Abuothman & Mutasem Taha. (2023) Vitamin B12 binding to mutated human transcobalamin, in-silico study of TCN2 alanine scanning and ClinVar missense mutations/SNPs. Journal of Biomolecular Structure and Dynamics 41:8, pages 3222-3233.
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Francisco Fernandes-Costa, J. Metz & Charles A. Hall. (1982) Vitamin B12 Binders (Transcobalamins) in Serum. CRC Critical Reviews in Clinical Laboratory Sciences 18:1, pages 1-30.
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Valentin Lacombe, Guy Lenaers & Geoffrey Urbanski. (2022) Diagnostic and Therapeutic Perspectives Associated to Cobalamin-Dependent Metabolism and Transcobalamins’ Synthesis in Solid Cancers. Nutrients 14:10, pages 2058.
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Utku Iltar, Mesut Göçer & Erdal Kurtoğlu. (2019) False elevations of vitamin B12 levels due to assay errors in a patient with pernicious anemia. BLOOD RESEARCH 54:2, pages 149-151.
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Jayme WorkingerRobert Doyle. 2017. Vitamin B12. Vitamin B12 338 364 .
Julia L Finkelstein, Alexander J Layden & Patrick J Stover. (2015) Vitamin B-12 and Perinatal Health. Advances in Nutrition 6:5, pages 552-563.
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Ebba Nexo & Elke Hoffmann-Lücke. (2011) Holotranscobalamin, a marker of vitamin B-12 status: analytical aspects and clinical utility. The American Journal of Clinical Nutrition 94:1, pages S1-S7.
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Pilar Ruiz-Sánchez. 2010. Ideas in Chemistry and Molecular Sciences. Ideas in Chemistry and Molecular Sciences 93 115 .
Tore Forsingdal Hardlei, Anne Louise Mørkbak, Mustafa Vakur Bor, Lynn B Bailey, Anne-Mette Hvas & Ebba Nexo. (2010) Assessment of Vitamin B12 Absorption Based on the Accumulation of Orally Administered Cyanocobalamin on Transcobalamin. Clinical Chemistry 56:3, pages 432-436.
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Anne L. Morkbak, Steen S. Poulsen & Ebba Nexo. (2007) Haptocorrin in humans. Clinical Chemical Laboratory Medicine 45:12.
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Henrik Birn. (2006) The kidney in vitamin B 12 and folate homeostasis: characterization of receptors for tubular uptake of vitamins and carrier proteins . American Journal of Physiology-Renal Physiology 291:1, pages F22-F36.
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Anne L Mørkbak, Anne-Mette Hvas, Zouë Lloyd-Wright, Tom AB Sanders, Øyvind Bleie, Helga Refsum, Ottar K Nygaard & Ebba Nexø. (2006) Effect of Vitamin B12 Treatment on Haptocorrin. Clinical Chemistry 52:6, pages 1104-1111.
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Anne L. Morkbak, Jette F. Pedersen & Ebba Nexo. (2005) Glycosylation independent measurement of the cobalamin binding protein haptocorrin. Clinica Chimica Acta 356:1-2, pages 184-190.
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Ralph Carmel. (2003) Mild Transcobalamin I (Haptocorrin) Deficiency and Low Serum Cobalamin Concentrations. Clinical Chemistry 49:8, pages 1367-1374.
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Ebba Nexo, Anna-Lisa Christensen, Anne-Mette Hvas, Torben E Petersen & Sergey N Fedosov. (2002) Quantification of Holo-Transcobalamin, a Marker of Vitamin B12 Deficiency. Clinical Chemistry 48:3, pages 561-562.
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Ralph Carmel. (2002) Measuring and Interpreting Holo-Transcobalamin (Holo-Transcobalamin II). Clinical Chemistry 48:3, pages 407-409.
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Gregory J. Russell-Jones & David H. Alpers. 2002. Membrane Transporters as Drug Targets. Membrane Transporters as Drug Targets 493 520 .
R. Carmel, H. Vasireddy, I. Aurangzeb & K. George. (2001) High serum cobalamin levels in the clinical setting - clinical associations and holo-transcobalamin changes. Clinical & Laboratory Haematology 23:6, pages 365-371.
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Ralph Carmel, Shabneet Brar & Zohreh Frouhar. (2001) Plasma Total Transcobalamin I. American Journal of Clinical Pathology 116:4, pages 576-580.
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RIKKE NIELSEN, BOE SANDAHL SØRENSEN, HENRIK BIRN, ERIK ILSØ CHRISTENSEN & EBBA NEXØ. (2001) Transcellular Transport of Vitamin B 12 in LLC-PK1 Renal Proximal Tubule Cells . Journal of the American Society of Nephrology 12:6, pages 1099-1106.
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Farès NamourJean-Luc OlivierIdrissia AbdelmouttalebCharles AdjallaRenée DebardColette SalvatJean-Louis Guéant. (2001) Transcobalamin codon 259 polymorphism in HT-29 and Caco-2 cells and in Caucasians: relation to transcobalamin and homocysteine concentration in blood. Blood 97:4, pages 1092-1098.
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Ebba Nexo, Anna-Lisa Christensen, Torben E Petersen & Sergey N Fedosov. (2000) Measurement of Transcobalamin by ELISA. Clinical Chemistry 46:10, pages 1643-1649.
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Jan Lindemans. 2000. Modern Chromatographic Analysis Of Vitamins. Modern Chromatographic Analysis Of Vitamins.
Lindgren, Kilander, Bagge & Nexø. (1999) Holotranscobalamin - a sensitive marker of cobalamin malabsorption. European Journal of Clinical Investigation 29:4, pages 321-329.
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Sheldon P. Rothenberg & Edward V. Quadros. (1995) 4 Transcobalamin II and the membrane receptor for the transcobalamin II-cobalamin complex. Baillière's Clinical Haematology 8:3, pages 499-514.
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C GrabauJ R Roth. (1992) A Salmonella typhimurium cobalamin-deficient mutant blocked in 1-amino-2-propanol synthesis. Journal of Bacteriology 174:7, pages 2138-2144.
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Mads Hansen, Peter Gimsing, Steen Ingeberg, Henning Jans & Ebba Nexø. (2009) Cobalamin binding proteins in patients with HIV infection. European Journal of Haematology 48:4, pages 228-231.
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Mads Hansen & Ebba Nexø. (1989) Isoelectric focusing of apo- and holo-transcobalamin present in human blood. Identification of a protein complexing with transcobalamin. Biochimica et Biophysica Acta (BBA) - General Subjects 992:2, pages 209-214.
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Zenon Schneider & Andrzej StroinskiZ. Schneider. 1987. Comprehensive B 12 . Comprehensive B 12 267 334 .
Marijke Fràter-Schröder. 1986. Vitamins and Coenzymes Part H. Vitamins and Coenzymes Part H 36 49 .
Joanne G. Crantz. (1985) Vitamin B, 12 Deficiency in the Elderly. Clinics in Geriatric Medicine 1:4, pages 701-710.
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R Carmel. (1985) The distribution of endogenous cobalamin among cobalamin-binding proteins in the blood in normal and abnormal states. The American Journal of Clinical Nutrition 41:4, pages 713-719.
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J. Lindemans, M. Schoester & J. van Kapel. (1983) Application of a simple immunoadsorption assay for the measurement of saturated and unsaturated transcobalamin II and R-binders. Clinica Chimica Acta 132:1, pages 53-61.
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Marijke Frater-Schroder, Lucja Kierat, Roger Y. Andres & Jürg Römer. (1982) Solid-phase immunoassay for the vitamin B12-binding protein transcobalamin II in human serum. Analytical Biochemistry 124:1, pages 92-101.
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J M Poston & B A Hemmings. (1979) Cobalamins and cobalamin-dependent enzymes in Candida utilis. Journal of Bacteriology 140:3, pages 1013-1016.
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Peter Gimsing & Erik Hippe. (2009) Increased Concentration of Transcobalamin I in a Patient with Metastatic Carcinoma of the Breast. Scandinavian Journal of Haematology 21:3, pages 243-249.
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Ebba Nexø. (2009) Transcobalamin I and other Human R‐Binders: Purification, Structural, Spectral and Physiological Studies. Scandinavian Journal of Haematology 20:3, pages 221-236.
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