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Original Article

A simple single injection method for determination of the extracellular fluid volume

Pages 567-573 | Received 16 Sep 1979, Accepted 14 Feb 1980, Published online: 08 Jul 2009

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Read on this site (18)

Ulrik L. Henriksen, Inge-Lis Kanstrup & Jens H. Henriksen. (2013) One-sample determination of glomerular filtration rate (GFR) in children. An evaluation based on 75 consecutive patients. Scandinavian Journal of Clinical and Laboratory Investigation 73:6, pages 466-475.
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J. Lysgård Madsen, O. Scharff, A. Rabøl & O. Worm Krogsgaard. (1996) Relationship between Small-Intestinal Transit Rate and Intestinal Absorption of 14C-labelled Mannitol and 51Cr-labelled Ethylenediaminetetraacetic Acid in Healthy Subjects. Scandinavian Journal of Gastroenterology 31:3, pages 254-259.
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S. Lundqvist, S.-O. Hietala, C. Berglund & K. Karp. (1994) Simultaneous Urography and Determination of Glomerular Filtration Rate. Acta Radiologica 35:4, pages 391-395.
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H. S. Thomsen, A. Vestergaard, K. Golman & S. Dorph. (1992) One or Two Samples for Determination of Total Plasma Clearance of a Nonionic Contrast Medium in Patients Undergoing Enhanced CT. Acta Radiologica 33:6, pages 588-591.
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A-L. Kamper, E. B. Pedersen, S. Strandgaard, N-H. Holstein-Rathlou, P. P. Leyssac, P. Skaarup, L. Hemmingsen, J. Holm & O. Munck. (1991) Atrial natriuretic peptide and renal adaptation to contralateral nephrectomy in healthy man. Scandinavian Journal of Clinical and Laboratory Investigation 51:1, pages 99-103.
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A-L. Kamper & O. J. Nielsen. (1990) Effect of enalapril on haemoglobin and serum erythropoietin in patients with chronic nephropathy. Scandinavian Journal of Clinical and Laboratory Investigation 50:6, pages 611-618.
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S. Groth & M. Aasted. (1989) Determination of 51Cr-EDTA Clearance Between 15 and 40 Ml/Min/1.73 M2 by a Single Plasma Sample. Scandinavian Journal of Clinical and Laboratory Investigation 49:8, pages 711-717.
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E. Hommel, E. R. Mathiesen, J. Giese, M. D. Nielsen, H. J. Schütten & H-H. Parving. (1989) On the pathogenesis of arterial blood pressure elevation early in the course of diabetic nephropathy. Scandinavian Journal of Clinical and Laboratory Investigation 49:6, pages 537-544.
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M. Boijsen, G. Granerus, L. Jacobsson, L. Björneld, M. Aurell & U. Tylén. (1988) Glomerular filtration rate estimated after multiple injections of contrast medium during angiography. Acta Radiologica 29:6, pages 669-674.
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Marianne Boijsen, L. Jacobsson & U. Tylén. (1987) Renal Function Measured by X-Ray Fluorescence Analysis. Acta Radiologica 28:5, pages 581-585.
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J. Brøchner-Mortensen, P. Paaby, P. Fjeldborg, K. Raffn, C. E. Larsen & J. Møller-Petersen. (1987) Renal haemodynamics and extracellular homeostasis during the menstrual cycle. Scandinavian Journal of Clinical and Laboratory Investigation 47:8, pages 829-835.
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H. O. Fadnes, J. F. Pape & J. A. Sundsfjord. (1986) A study on oedema mechanism in nephrotic syndrome. Scandinavian Journal of Clinical and Laboratory Investigation 46:6, pages 533-538.
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Bent A. Jacobsen & Paul Fjeldborg. (1986) Renal haemodynamics during propranolol treatment in patients with arterial hypertension and chronic renal failure. Scandinavian Journal of Clinical and Laboratory Investigation 46:3, pages 289-292.
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Ole M. Nielsen. (1985) Extracellular volume, renal clearance and whole body permeability—surface area product in man, measured after single injection of polyfructosan. Scandinavian Journal of Clinical and Laboratory Investigation 45:3, pages 217-222.
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J. Brøchner-Mortensen. (1982) The extracellular fluid volume in normal man determined as the distribution volume of [51Cr] EDTA. Scandinavian Journal of Clinical and Laboratory Investigation 42:3, pages 261-264.
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J. Brøchner-Mortensen, H. Rickers & I. Balslev. (1980) Renal function and body composition before and after intestinal bypass operation in obese patients. Scandinavian Journal of Clinical and Laboratory Investigation 40:8, pages 695-702.
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Articles from other publishers (35)

Bárbara Martínez de Miguel, Elena Dobra Neacsu, Carla de Gracia González & Rebeca Pérez Pascual. (2023) Effect of indexed glomerular filtration rate according to age. Clinical and Experimental Nephrology 27:7, pages 631-638.
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James Warwick & Jennifer Holness. (2022) Measurement of Glomerular Filtration Rate. Seminars in Nuclear Medicine 52:4, pages 453-466.
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Anne-Laure Faucon, Martin Flamant, Pierre Delanaye, Oriane Lambert, Marie Essig, Marie-Noëlle Peraldi, Nahid Tabibzadeh, Jean-Philippe Haymann, Bénédicte Stengel, Guillaume Geri & Emmanuelle Vidal-Petiot. (2022) Estimating Extracellular Fluid Volume in Healthy Individuals: Evaluation of Existing Formulae and Development of a New Equation. Kidney International Reports 7:4, pages 810-822.
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Jesper Jensen, Massar Omar, Caroline Kistorp, Mikael Kjær Poulsen, Christian Tuxen, Ida Gustafsson, Lars Køber, Finn Gustafsson, Emil Fosbøl, Niels Eske Bruun, Lars Videbæk, Peter Hartmund Frederiksen, Jacob Eifer Møller & Morten Schou. (2019) Empagliflozin in heart failure patients with reduced ejection fraction: a randomized clinical trial (Empire HF). Trials 20:1.
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Anne-Laure Faucon, Martin Flamant, Marie Metzger, Jean-Jacques Boffa, Jean-Philippe Haymann, Pascal Houillier, Eric Thervet, François Vrtovsnik, Bénédicte Stengel, Guillaume Geri, Emmanuelle Vidal-Petiot, François Vrtovsnik, Eric Daugas, Nahid Tabibzadeh, Martin Flamant, Emmanuelle Vidal-Petiot, Alexandre Karras, Stéphane Roueff, Eric Thervet, Pascal Houillier, Marie Courbebaisse, Caroline Prot-Bertoye, Jean-Philippe Bertocchio, Gérard Maruani, Jean-Jacques Boffa, Pierre Ronco, Hafedh Fessi, Eric Rondeau, Marine Livrozet, Emmanuel Letavernier, Jean-Philippe Haymann, Marie Metzger, Pablo Urena-Torres & Bénédicte Stengel. (2019) Extracellular fluid volume is associated with incident end-stage kidney disease and mortality in patients with chronic kidney disease. Kidney International 96:4, pages 1020-1029.
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Maria-Eleni Roumelioti, Robert H Glew, Zeid J Khitan, Helbert Rondon-Berrios, Christos P Argyropoulos, Deepak Malhotra, Dominic S Raj, Emmanuel I Agaba, Mark Rohrscheib, Glen H Murata, Joseph I Shapiro & Antonios H Tzamaloukas. (2018) Fluid balance concepts in medicine: Principles and practice. World Journal of Nephrology 7:1, pages 1-28.
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Katalin Kiss, Miklós Molnár, Sören Söndergaard, Gyula Molnár & Sven-Erik Ricksten. (2018) Mannitol clearance for the determination of glomerular filtration rate-a validation against clearance of 51 Cr-EDTA . Clinical Physiology and Functional Imaging 38:1, pages 10-16.
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Peter K. Bonfils, Mustafa Taskiran, Morten Damgaard, Jens P. Goetze, Andrea K. Floyd, Peter Funch-Jensen, Viggo B. Kristiansen, Mikael Støckel, Pierre N. Bouchelouche & Niels Gadsbøll. (2015) Roux-en-Y gastric bypass alleviates hypertension and is associated with an increase in mid-regional pro-atrial natriuretic peptide in morbid obese patients. Journal of Hypertension 33:6, pages 1215-1225.
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Peter K. Bonfils, Mustafa Taskiran, Morten Damgaard, Jens P. Goetze, Andrea K. Floyd, Peter Funch-Jensen, Viggo B. Kristiansen & Niels Gadsbøll. (2013) The influence of high versus low sodium intake on blood pressure and haemodynamics in patients with morbid obesity. Journal of Hypertension 31:11, pages 2220-2229.
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Y. Funakoshi, Y. Fujiwara, N. Kiyota, T. Mukohara, T. Shimada, M. Toyoda, Y. Imamura, N. Chayahara, M. Umezu, N. Otsuki, K.-i. Nibu & H. Minami. (2013) Prediction of Glomerular Filtration Rate in Cancer Patients by an Equation for Japanese Estimated Glomerular Filtration Rate. Japanese Journal of Clinical Oncology 43:3, pages 271-277.
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Lars Jødal & Jens Brøchner-Mortensen. (2012) Simplified methods for assessment of renal function as the ratio of glomerular filtration rate to extracellular fluid volume. Nuclear Medicine Communications 33:12, pages 1243-1253.
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Alison G. Abraham, Alvaro Muñoz, Susan L. Furth, Bradley Warady & George J. Schwartz. (2011) Extracellular Volume and Glomerular Filtration Rate in Children with Chronic Kidney Disease. Clinical Journal of the American Society of Nephrology 6:4, pages 741-747.
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Peter K. Bonfils, Morten Damgaard, Mustafa Taskiran, Jens Peter Goetze, Peter Norsk & Niels Gadsbøll. (2010) Impact of diuretic treatment and sodium intake on plasma volume in patients with compensated systolic heart failure. European Journal of Heart Failure 12:9, pages 995-1001.
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Nicholas J Bird, A Robert Michell & A Michael Peters. (2009) Accurate measurement of extracellular fluid volume from the slope/intercept technique after bolus injection of a filtration marker. Physiological Measurement 30:12, pages 1371-1379.
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Folkert W. Visser, Jaap H. J. Muntinga, Rudi A. Dierckx & Gerjan Navis. (2008) Feasibility and Impact of the Measurement of Extracellular Fluid Volume Simultaneous with GFR by 125 I-Iothalamate . Clinical Journal of the American Society of Nephrology 3:5, pages 1308-1315.
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Philip S. Cosgriff, John S. Fleming, Peter H. Jarritt, John Skrypniuk, Dale Bailey, Dave Whalley, Alex Houston, Maria Burniston & Glen M. Blake. (2008) UK audit of glomerular filtration rate measurement in 2001. Nuclear Medicine Communications 29:6, pages 511-520.
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WALTER S. WATSON. (2000) How good is the slope on the second exponential for estimating 51Cr-EDTA renal clearance? A Monte Carlo simulation. Nuclear Medicine Communications 21:12, pages 1162-1163.
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W S WATSON. (2000) Body surface area correction in single-sample methods of glomerular filtration rate estimation. Nuclear Medicine Communications 21:1, pages 121-122.
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A M Peters, B L Henderson, D Lui, M Blunkett, P S Cosgriff & M J Myers. (1999) Appropriate corrections to glomerular filtration rate and volume of distribution based on the bolus injection and single-compartment technique. Physiological Measurement 20:3, pages 313-327.
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Henrik P. Hansen, Peter Rossing, Lise Tarnow, Flemming S. Nielsen, Berit R. Jensen & Hans-Henrik Parving. (1996) Circadian rhythm of arterial blood pressure and albuminuria in diabetic nephropathy. Kidney International 50:2, pages 579-585.
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A Gleadhill, A.M Peters & A.R Michell. (1995) A simple method for measuring glomerular filtration rate in dogs. Research in Veterinary Science 59:2, pages 118-123.
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J. S. JENSEN, K. BORCH‐JOHNSEN, T. DECKERT, M. DECKERT, G. JENSEN & B. FELDT‐RASMUSSEN. (2008) Reduced glomerular size‐ and charge‐selectivity in clinically healthy individuals with microalbuminuria. European Journal of Clinical Investigation 25:8, pages 608-614.
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H. Mulec, G. Blohm�, K. Kullenberg, G. Nyberg & S. Bj�rck. (1995) Latent overhydration and nocturnal hypertension in diabetic nephropathy. Diabetologia 38:2, pages 216-220.
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A. Michael Peters, Helen Allison & W. Yu. Ussov. (1994) Measurement of the ratio of glomerular filtration rate to plasma volume from the technetium-99m diethylene triamine pentaacetic acid renogram: comparison with glomerular filtration rate in relation to extracellular fluid volume. European Journal of Nuclear Medicine 21:4, pages 322-327.
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M. Rehling & A. Rabøl. (2008) Measurement of glomerular filtration rate in adults: accuracy of five single‐sample plasma clearance methods. Clinical Physiology 9:2, pages 171-182.
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M. Boijsen, L. Jacobsson & U. Tylén. (2008) Glomerular filtration rate estimated from a single plasma sample after contrast‐enhanced radiological examinations. Clinical Physiology 8:3, pages 309-316.
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B. Feldt-Rasmussen, E. R. Mathiesen, T. Deckert, J. Giese, N. J. Christensen, L. Bent-Hansen & M. D. Nielsen. (1987) Central role for sodium in the pathogenesis of blood pressure changes independent of angiotensin, aldosterone and catecholamines in Type 1 (insulin-dependent) diabetes mellitus. Diabetologia 30:8, pages 610-617.
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Kurt Feddersen, Claes Arén, Göran Granérus, Rudolf Jagenburg & Kjell Rådegran. (1985) Effects of Prostacyclin Infusion on Renal Function during Cardiopulmonary Bypass. The Annals of Thoracic Surgery 40:1, pages 16-19.
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J. H. KRISTIANSEN, J. BROCHNER MORTENSEN & K. O. PEDERSEN. (1985) FAMILIAL HYPOCALCIURIC HYPERCALCAEMIA I: RENAL HANDLING OF CALCIUM, MAGNESIUM AND PHOSPHATE. Clinical Endocrinology 22:1, pages 103-116.
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P. L. Eberstadt. (1984) Comparative study of glomerular filtration rate with diverse labelled agents. International Urology and Nephrology 16:1, pages 3-11.
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Steffen Groth. (2008) Calculation of 51 Cr‐EDTA clearance in children from the activity in one plasma sample by transformation of the biexponential plasma time‐activity curve into a monoexponential with identical integral area below the time‐activity curve . Clinical Physiology 4:1, pages 61-74.
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O. SchückO. Schück. 1984. Examination of Kidney Function. Examination of Kidney Function 9 43 .
Lars Jacobsson. (2008) A method for the calculation of renal clearance based on a single plasma sample. Clinical Physiology 3:4, pages 297-305.
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STEEN VADSTRUP & JØRGEN BOJSEN. (2008) The glomerular filtration rate in unrestrained rabbits determined by means of an implanted telemetrical device. Acta Physiologica Scandinavica 117:2, pages 177-182.
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Jens Brøchner-Mortensen & Jørn Ditzel. (1982) Glomerular filtration rate and extracellular fluid volume in insulin-dependent patients with diabetes mellitus. Kidney International 21:5, pages 696-698.
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