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Original Article

Radioreceptor assay for benzodiazepines in biological fluids using a new dry and stable receptor preparation

Pages 275-280 | Received 15 Jan 1980, Accepted 26 Aug 1980, Published online: 08 Jul 2009

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Toshifumi Takeuchi, Shunitz Tanaka & GarryA. Rechnitz. (1991) Non-Isotopic Receptor Assay for Benzodiazepine Drugs Using Biotin-Benzodiazepine Conjugate. Analytical Letters 24:12, pages 2111-2121.
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K. Ensing, W.G. In'T Hout & R.A. De Zeeuw. (1987) Lyophilised Receptor Preparation for A Radioreceptor Assay for Anticholinergics. Analytical Letters 20:3, pages 489-502.
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J. G. Richards, H. Möhler, P. Schoch, P. Häring, B. Takacs & Ch. Stähli. (1984) The Visualization of Neuronal Benzodiazepine Receptors in the Brain by Autoradiography and Immunohistochemistry. Journal of Receptor Research 4:1-6, pages 657-669.
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R. Sherman-gold, Y. Dudai, L. Fogelfeld & S. Fuchs. (1983) Production of a High Affinity Antiserum to Benzodiazepines. Journal of Immunoassay 4:2, pages 135-146.
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Willy Haefely. (1983) The Biological Basis of Benzodiazepine Actions. Journal of Psychoactive Drugs 15:1-2, pages 19-39.
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Emma Fluck, Cathy Fernandes, Sandra E. File, H.Valerie Curran & Jane Marshall. (1998) The Influence of Alcoholism and Cirrhosis on Benzodiazepine Receptor Function. Pharmacology Biochemistry and Behavior 59:4, pages 949-954.
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Gerhard T Viel, Qing Yang, Per Lundahl, Kees Ensing & Rokus A de Zeeuw. (1997) Size-exclusion chromatographic reconstitution of the bovine brain benzodiazepine receptor. Journal of Chromatography A 776:1, pages 101-107.
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J. Šmisterová, K. Ensing & R.A. de Zeeuw. (1994) Methodological aspects of quantitative receptor assays. Journal of Pharmaceutical and Biomedical Analysis 12:6, pages 723-745.
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Jean‐Philippe Boulenger, Lars F. Gram, Françlois B. Jolicoeur & Edouard Zarifian. (2004) Repeated administration of buspirone: Absence of pharmacodynamic or pharmacokinetic interaction with triazolam. Human Psychopharmacology: Clinical and Experimental 8:2, pages 117-124.
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A. Steentoft & K. Worm. (1993) Cases of fatal triazolam poisoning. Journal of the Forensic Science Society 33:1, pages 45-48.
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Maria A. Perillo & Daniel A. Garcia. (2005) Non‐labelled benzodiazepines partitioned into synaptosomal membranes: their extraction and quantification by high performance liquid chromatography. Biomedical Chromatography 6:4, pages 183-190.
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Toshifumi Takeuchi, Shunitz Tanaka & Garry A. Rechnitz. (1992) Biotinylated 1012-S conjugate as a probe ligand for benzodiazepine receptors: Characterization of receptor binding sites and receptor assay for benzodiazepine drugs. Analytical Biochemistry 203:1, pages 158-162.
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Sven J. Dencker, Gunvor Johansson & Ian Milsom. (1992) Quantification of naturally occurring benzodiazepine-like substances in human breast milk. Psychopharmacology 107:1, pages 69-72.
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P. Christensen, A. Lolk, L. F. Gram & P. Kragh-Sørensen. (1992) Benzodiazepine-induced sedation and cortisol suppression. Psychopharmacology 106:4, pages 511-516.
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J.E.C. Burnett, J.S. Oliver & H. Smith. (1989) Radioreceptor assay and radioimmunoassay of triazolam in urine samples from racing greyhounds. Forensic Science International 43:2, pages 199-205.
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S. J. Dencker & G. Johansson. (1989) Radioreceptor assay for checking benzodiazepine intake. Psychopharmacology 97:4, pages 561-562.
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Lars Nordholm & Helle Mengel. (1989) Determination of an oxadiazole-substituted 1,4-benzodiazepine in plasma by high-performance liquid chromatography with ultraviolet detection and by a radioreceptor assay. Journal of Chromatography B: Biomedical Sciences and Applications 494, pages 257-265.
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L. KNUDSEN, L. LONKA, B. H. SØRENSEN, L. KIRKEGAARD, O. V. JENSEN & S. JENSEN. (2007) Benzodiazepine intoxication treated with flumazenil (Anexate, RO 15–1788). Anaesthesia 43:4, pages 274-276.
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Mahmoud M.A. Hassan & Mahmoud A. Abounassif. 1987. 1 51 .
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P. Crevat-Pisano, C. Hariton, P.H. Rolland & J.P. Cano. (1986) Fundamental aspects of radioreceptor assays. Journal of Pharmaceutical and Biomedical Analysis 4:6, pages 697-716.
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M. Danhof, J. Dingemanse & D. D. Breimer. 1986. BIOACTIVE ANALYTES, Including CNS Drugs, Peptides, and Enantiomers. BIOACTIVE ANALYTES, Including CNS Drugs, Peptides, and Enantiomers 141 148 .
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Karen Worm, Hanne Christensen & Anni Steentoft. (1985) Diazepam in Blood of Danish Drivers: Occurrence as shown by Gas–Liquid Chromatographic Assay following Radioreceptor Screening. Journal of the Forensic Science Society 25:6, pages 407-413.
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Dorothy W. Gallager, Andrea B. Malcolm, Stewart A. Anderson & Susan F. Gonsalvez. (1985) Continuous release of diazepam: Electrophysiological, biochemical and behavioral consequences. Brain Research 342:1, pages 26-36.
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C. Becherucci, M. Palmi & G. Segre. (1985) Pharmacokinetics of flunitrazepam in rats studied by a radioreceptor assay. Pharmacological Research Communications 17:8, pages 733-747.
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Hanne Christensen, Anni Steentoft & Karen Worm. (1985) Muscle as an Autopsy Material for Evaluation of Fatal Cases of Drug Overdose. Journal of the Forensic Science Society 25:3, pages 191-206.
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Willy Haefely. 1985. The Benzodiazepines: Current Standards for Medical Practice. The Benzodiazepines: Current Standards for Medical Practice 7 41 .
Jennifer L. Tyma, Howard C. Rosenberg & Ted H. Chiu. (1984) Radioreceptor assay of benzodiazepines in cerebrospinal fluid during chronic flurazepam treatment in cats. European Journal of Pharmacology 105:3-4, pages 301-308.
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Hitoshi Sato, Yuichi Sugiyama, Yasufumi Sawada, Tatsuji Iga & Manabu Hanano. (1984) Pharmacokinetic study of exogenously administered ß-endorphin using a rapid radioreceptor assay in rats. Life Sciences 35:10, pages 1051-1059.
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Jouko Tuomisto, Päivi Tuomainen & Veijo Saano. (2009) Comparison of Gas Chromatography and Receptor Bioassay in the Determination of Diazepam in Plasma after Conventional Tablets and Controlled Release Capsules. Acta Pharmacologica et Toxicologica 55:1, pages 50-57.
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Roman Lapka, Stanislav Šmolík & Zdeněk Franc. (1984) Radioreceptor assay for ergot derivatives, transdihydrolisuride and lisuride, in biological fluids. Journal of Pharmacological Methods 11:4, pages 263-270.
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David N. Stephens, Wolfgang Kehr, Herbert H. Schneider & Ralph Schmiechen. (1984) β-Carbolines with agonistic and inverse agonistic properties at benzodiazepine receptors of the rat. Neuroscience Letters 47:3, pages 333-338.
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D. W. Gallager, J. M. Lakoski, S. F. Gonsalves & S. L. Rauch. (1984) Chronic benzodiazepine treatment decreases postsynaptic GABA sensitivity. Nature 308:5954, pages 74-77.
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Richard B. Mailman, Diane L. DeHaven, Emily A. Halperin & Mark H. Lewis. (1984) Serum effects confound the neuroleptic radioreceptor assay. Life Sciences 34:11, pages 1057-1064.
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R. Dorow. 1984. Sleep, Benzodiazepines and Performance. Sleep, Benzodiazepines and Performance 105 118 .
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Brian S. Meldrum, Mary C. Evans & Claus Braestrup. (1983) Anticonvulsant action in the photosensitive baboon, Papio papio, of a novel β-carboline derivative, ZK 91296. European Journal of Pharmacology 91:2-3, pages 255-259.
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F. Nielsen‐Kudsk, T. Staehelin Jensen, I. Magnussen, P. Jakobsen, P. B. Jensen, K. Mondrup & T. Petersen. (2009) Pharmacokinetics and Bioavailability of Intravenous and Intramuscular Lorazepam with an Adjunct Test of the Inattention Effect in Humans. Acta Pharmacologica et Toxicologica 52:2, pages 121-127.
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Ph. Coassolo, C. Aubert & J.P. Cano. (1983) Simultaneous assay of triazolam and its main hydroxy metabolite in plasma and urine by capillary gas chromatography. Journal of Chromatography B: Biomedical Sciences and Applications 274, pages 161-170.
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Claus Braestrup & Mogens Nielsen. 1983. Biochemical Studies of CNS Receptors. Biochemical Studies of CNS Receptors 285 384 .
RG Dorow, J Seidler & HH Schneider. (2012) A radioreceptor assay to study the affinity of benzodiazepines and their receptor binding activity in human plasma including their active metabolites.. British Journal of Clinical Pharmacology 13:4, pages 561-565.
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Gabor Kato & Thomas Ban. (1982) Central nervous system receptors in neuropsychiatric disorders. Progress in Neuro-Psychopharmacology and Biological Psychiatry 6:3, pages 207-222.
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