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Scandinavian Journal of Clinical and Laboratory Investigation Volume 44, 1984 - Issue 2
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Original Article

Urinary 99m-Tc-diphosphonate excretion as a simple method to quantify bone metabolism

Lars Hyldstrup Department of Clinical Immunology and Blood Transfusion, Hvidovre Hospital, University of Copenhagen, Denmark; Department of Clinical Physiology, Hvidovre Hospital, University of Copenhagen, Denmark
,
Nikolaj Mogensen Department of Clinical Physiology, Hvidovre Hospital, University of Copenhagen, Denmark
,
Grethe Finn Jensen Division of Endocrinology, Hvidovre Hospital, University of Copenhagen, Denmark; Department of Internal Medicine, Hvidovre Hospital, University of Copenhagen, Denmark
,
Peter McNair Division of Endocrinology, Hvidovre Hospital, University of Copenhagen, Denmark; Department of Internal Medicine, Hvidovre Hospital, University of Copenhagen, Denmark
&
Ib Transbøl Division of Endocrinology, Hvidovre Hospital, University of Copenhagen, Denmark; Department of Internal Medicine, Hvidovre Hospital, University of Copenhagen, Denmark
Pages 105-109 | Received 14 May 1983, Accepted 03 Oct 1983, Published online: 05 Aug 2009

Citations (18)

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Read on this site (4)

L. Hyldstrup, P. McNair & I. Transbøl. (1988) GFR-corrected 24-hour whole body retention of diphosphonate: An improved index of bone metabolism. Scandinavian Journal of Clinical and Laboratory Investigation 48:4, pages 341-345.
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L. Hyldstrup, I. Clemmensen, B. A. Jensen & I. Transbøl. (1988) Non-invasive evaluation of bone formation: Measurements of serum alkaline phosphatase, whole body retention of diphosphonate and serum osteocalcin in metabolic bone disorders and thyroid disease. Scandinavian Journal of Clinical and Laboratory Investigation 48:7, pages 611-619.
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Karsten Thomsen, Anders Gotfredsen & Claus Christiansen. (1986) Bone turnover in healthy adults measured by whole body retention and urinary excretion of 99mTc-MDP. Normalization by bone mass. Scandinavian Journal of Clinical and Laboratory Investigation 46:6, pages 587-592.
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Lars Hiyldstrup, Peter McNair, Grethe Finn Jensen, Nikolaj Bokg Mogensen & Ib Transbøl. (1984) Measurements of whole body retention of diphosphonate and other indices of bone metabolism in 125 normals: Dependency on age, sex and glomerular filtration. Scandinavian Journal of Clinical and Laboratory Investigation 44:8, pages 673-678.
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Articles from other publishers (14)

Serge Cremers, Frank (Hal) Ebetino & Roger Phipps. (2020) On the pharmacological evaluation of bisphosphonates in humans. Bone 139, pages 115501.
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Serge Cremers & Socrates Papapoulos. (2011) Pharmacology of bisphosphonates. Bone 49:1, pages 42-49.
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Glen M. Blake, Amelia E.B. Moore & Ignac Fogelman. (2009) Quantitative Studies of Bone Using 99mTc-Methylene Diphosphonate Skeletal Plasma Clearance. Seminars in Nuclear Medicine 39:6, pages 369-379.
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Serge C L M Cremers, Goonaseelan (Colin) Pillai & Socrates E Papapoulos. (2005) Pharmacokinetics/Pharmacodynamics of Bisphosphonates. Clinical Pharmacokinetics 44:6, pages 551-570.
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G. M. BLAKE, A. E.B. MOORE, S.-J. PARK-HOLOHAN & I. FOGELMAN. (2003) A direct in vivo measurement of 99mTc-methylene diphosphonate protein binding. Nuclear Medicine Communications 24:7, pages 829-835.
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S. Cremers, E. Eekhoff, S. v. Dam, J. Den Hartigh, H. Hamdy, P. Vermeij & S. Papapoulos. (2002) Bisphosphonate (olpadronate) retention and its determinants in Paget's disease of bone. British Journal of Clinical Pharmacology 53:5, pages 544P-545P.
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Glen M. Blake, So-Jin Park-Holohan, Gary J.R. Cook & Ignac Fogelman. (2001) Quantitative studies of bone with the use of 18F-fluoride and 99mTc-methylene diphosphonate. Seminars in Nuclear Medicine 31:1, pages 28-49.
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S. Gonnelli, C. Cepollaro, C. Pondrelli, S. Martini, R. Monaco & C. Gennari. (2009) The Usefulness of Bone Turnover in Predicting the Response to Transdermal Estrogen Therapy in Postmenopausal Osteoporosis. Journal of Bone and Mineral Research 12:4, pages 624-631.
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L. Hyldstrup, G. Flesch & S. A. Hauffe. (1993) Pharmacokinetic evaluation of pamidronate after oral administration: A study on dose proportionality, absolute bioavailability, and effect of repeated administration. Calcified Tissue International 53:5, pages 297-300.
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C. Gennari, D. Agnusdei & A. Camporeale. (1993) Effect of salmon calcitonin nasal spray on bone mass in patients with high turnover osteoporosis. Osteoporosis International 3:S1, pages 208-210.
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R.C. Puche, A. Rigalli, L. Trumper, O. Dip, J.L. Pereyra, G. Poudes, A Roberti, R. Bocanera & R. Tozzini. (1991) Estimation of bone turnover in climacteric women by the whole body retention of fluoride. Maturitas 14:1, pages 57-64.
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S. Molloi, R. Mazess, H. Bendsen & M. Wilson. (1989) Whole body and regional retention of Tc-99m-labeled diphosphonates with a whole-body counter: A study with normal males. Calcified Tissue International 44:5, pages 322-329.
Crossref
Lars Hyldstrup, Peter McNair, Poul Ring & Ole Henriksen. (1987) Studies on diphosphonate kinetics. European Journal of Nuclear Medicine 12:12, pages 585-588.
Crossref
Karsten Thomsen, Lisbeth Nilas, Torben Mogensen & Claus Christiansen. (1986) Determination of bone turnover by urinary excretion of 99mTc-MDP. European Journal of Nuclear Medicine 12:7, pages 342-345.
Crossref

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