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Scandinavian Journal of Clinical and Laboratory Investigation Volume 45, 1985 - Issue 7
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Original Article

Purification of the pepsinogen A isozymogens by means of high resolution ion-exchange chromatography. Evidence for post-translational modifications

J. Défize Institute of Human Genetics and Department of Gastroenterology, Faculty of Medicine, Free University, Amsterdam, The Netherlands
,
G. Pals Institute of Human Genetics and Department of Gastroenterology, Faculty of Medicine, Free University, Amsterdam, The Netherlands
,
J. C. Pronk Institute of Human Genetics and Department of Gastroenterology, Faculty of Medicine, Free University, Amsterdam, The Netherlands
,
R. R. Frants Institute of Human Genetics and Department of Gastroenterology, Faculty of Medicine, Free University, Amsterdam, The Netherlands
,
G. Rimmelzwaan Institute of Human Genetics and Department of Gastroenterology, Faculty of Medicine, Free University, Amsterdam, The Netherlands
,
B. D. Wester Veld Department of Gastroenterology, Faculty of Medicine, Free University, Amsterdam, The Netherlands
&
A. W. Eriksson Institute of Human Genetics and Department of Gastroenterology, Faculty of Medicine, Free University, Amsterdam, The Netherlands
 show all
Pages 649-655 | Received 16 Nov 1984, Accepted 20 May 1985, Published online: 08 Jul 2009

Citations (13)

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Read on this site (4)

A. L. Jensen & B. Foltmann. (1996) Determination of phosphoserine in human pepsinogens. Scandinavian Journal of Clinical and Laboratory Investigation 56:1, pages 69-74.
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M. Plebani & Or. Sander Szabo. (1993) Pepsinogens in Health and Disease. Critical Reviews in Clinical Laboratory Sciences 30:3, pages 273-328.
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R. T. Taggart. (1992) Genetic variation of human aspartic proteinases. Scandinavian Journal of Clinical and Laboratory Investigation 52:sup210, pages 111-119.
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Gerard Pals, Vesa Räsänen, Stephan G. M. Meuwissen, Rune R. Frants, Pieter J. Kostense & Aldur W. Eriksson. (1987) Enzyme-linked immunosorbent assay and radioimmunoassay of serum pepsinogen A. Scandinavian Journal of Clinical and Laboratory Investigation 47:1, pages 29-33.
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Articles from other publishers (9)

Ruud A. Bank, Aldur W. Eriksson & Gerard Pals. (1991) High-performance liquid chromatography: purification and chromatographic behaviour of molecular variants of pepsinogen A from human urine. Journal of Chromatography B: Biomedical Sciences and Applications 571:1-2, pages 47-59.
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W. Wnuk & E. Loizeau. 1992. Structure and Function of the Aspartic Proteinases. Structure and Function of the Aspartic Proteinases 91 94 .
Gerard Pals, Takeshi Azuma, T.K. Mohandas, Graeme I. Bell, James Bacon, I.Michael Samloff, Daniel A. Walz, Philip J. Barr & R.Thomas Taggart. (1989) Human pepsinogen C (progastricsin) polymorphism: Evidence for a single locus located at 6p21.1-pter. Genomics 4:2, pages 137-145.
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Ruud A. Bank, Bart C. Crusius, Toon Zwiers, Stephan G.M. Meuwissen, Fre Arwert & Jan C. Pronk. (1988) Identification of a Glu > Lys substitution in the activation segment of human pepsinogen A-3 and -5 isozymogens by peptide mapping using endoproteinase Lys-C. FEBS Letters 238:1, pages 105-108.
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G. Pals, A. W. Eriksson, J. C. Pronk, R. R. Frants, E. C. Klinkenberg-Knol, A. Bosma, B. D. Westerveld, R. T. Taggart, I. M. Samloff & S. G. M. Meuwissen. (2008) Differential expression of pepsinogen isozymogens in a patient with Barrett esophagus. Clinical Genetics 34:2, pages 90-97.
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Gerard Pals, Barend D. Westerveld, Jacques Defize, Jan C. Pronk, Henk Brand, Marja Flipse, Cor Verwey, Stephan G. M. Meuwissen & Aldur W. Eriksson. (1988) Discrepancies between gastric mucosal and urinary pepsinogen A patterns andin vitro synthesis and secretion of human pepsinogen. Digestive Diseases and Sciences 33:2, pages 135-143.
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Marie Pauline J. Evers, Bauke Zelle, Daniel S. Peeper, Willem H. Mager, Rudi J. Planta, Aldur W. Eriksson & Rune R. Frants. (1987) Molecular cloning of a pair of human pepsinogen A genes which differ by a Glu?Lys mutation in the activation peptide. Human Genetics 77:2, pages 182-187.
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R.Thomas Taggart & I.Michael Samloff. (1987) Immunochemical, electrophoretic, and genetic heterogeneity of pepsinogen I. Gastroenterology 92:1, pages 143-150.
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B. D. Westerveld, G. Pals, J. Defize, J. C. Pronk, R. R. Frants, E. C. M. Ooms, J. Kreuning, A. W. Eriksson & S. G. M. Meuwissen. (2008) Pepsinogen A polymorphism in gastric mucosa and urine, with special reference to patients with gastric cancer. Clinical Genetics 30:3, pages 202-212.
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