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Scandinavian Journal of Clinical and Laboratory Investigation Volume 45, 1985 - Issue 2
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Original Article

L-Carnitine and haemodialysis

Double blind study on muscle function and metabolism and peripheral nerve function

Birger Fagher Department of Internal Medicine, University Hospital, Lund
,
Gitten Cederblad Department of Clinical Nutrition, Sahlgren's Hospital, University of Gothenburg, Lund, Sweden
,
Margareta Eriksson Departments of Clinical Neurophysiology, University Hospital, Lund, Sweden
,
Mario Monti Department of Internal Medicine, University Hospital, Lund
,
Ulrich Moritz Departments of Physical Medicine, University Hospital, Lund, Sweden
,
Peter Nilsson-Ehle Departments of Clinical Chemistry, University Hospital, Lund, Sweden
&
Hans Thysell Departments of Nephrology, University Hospital, Lund, Sweden
 show all
Pages 169-178 | Received 13 Jun 1984, Accepted 02 Oct 1984, Published online: 08 Jul 2009

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Shohei Kaneko, Keiji Hirai, Junki Morino, Saori Minato, Katsunori Yanai, Yuko Mutsuyoshi, Hiroki Ishii, Momoko Matsuyama, Taisuke Kitano, Mitsutoshi Shindo, Akinori Aomatsu, Haruhisa Miyazawa, Yuichiro Ueda, Kiyonori Ito, Susumu Ookawara & Yoshiyuki Morishita. (2020) Association between carnitine deficiency and the erythropoietin resistance index in patients undergoing peritoneal dialysis: a cross-sectional observational study. Renal Failure 42:1, pages 146-153.
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Eric P. Brass & William R. Hiatt. (1998) The Role of Carnitine and Carnitine Supplementation During Exercise in Man and in Individuals with Special Needs. Journal of the American College of Nutrition 17:3, pages 207-215.
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Birger Fagher, Mario Monti, Peter Nilsson-Ehle & Hans Thysell. (1987) Reduced thermogenesis in muscle and disturbed lipoprotein metabolism in relation to thyroid function in haemodialysis patients. Scandinavian Journal of Clinical and Laboratory Investigation 47:1, pages 91-97.
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Articles from other publishers (35)

Norihiro Nishioka, Yan Luo, Takuya Taniguchi, Tsuyoshi Ohnishi, Miho Kimachi, Roland CK Ng & Norio Watanabe. (2022) Carnitine supplements for people with chronic kidney disease requiring dialysis. Cochrane Database of Systematic Reviews 2022:12.
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Hiroyuki Takashima, Takashi Maruyama & Masanori Abe. (2021) Significance of Levocarnitine Treatment in Dialysis Patients. Nutrients 13:4, pages 1219.
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Rui Wang, Liuxin Wang, Caishun Zhang, Yan Zhang, Yuan Liu, Limin Song, Ruixia Ma & Jing Dong. (2018) L-carnitine ameliorates peripheral neuropathy in diabetic mice with a corresponding increase in insulin‑like growth factor‑1 level. Molecular Medicine Reports.
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Yasuo Kudoh, Shinya Aoyama, Takaaki Torii, Qijie Chen, Daigo Nagahara, Hiromi Sakata & Akihiko Nozawa. (2014) The Effects of Oral <smlcap>L</smlcap>-Carnitine Supplementation on Physical Capacity and Lipid Metabolism in Chronic Hemodialysis Patients. Nephron Extra 4:1, pages 33-41.
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Yizhi Chen, Manuela Abbate, Li Tang, Guangyan Cai, Zhixiang Gong, Ribao Wei, Jianhui Zhou & Xiangmei Chen. (2014) l-Carnitine supplementation for adults with end-stage kidney disease requiring maintenance hemodialysis: a systematic review and meta-analysis. The American Journal of Clinical Nutrition 99:2, pages 408-422.
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Robert Ringseis, Janine Keller & Klaus Eder. (2013) Mechanisms underlying the anti-wasting effect of l-carnitine supplementation under pathologic conditions: evidence from experimental and clinical studies. European Journal of Nutrition 52:5, pages 1421-1442.
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Alan G. Wasserstein. (2013) L-Carnitine Supplementation in Dialysis: Treatment in Quest of Disease. Seminars in Dialysis 26:1, pages 11-15.
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STEPHANIE E REUTER, RANDALL J FAULL & ALLAN M EVANS. (2007) L-carnitine supplementation in the dialysis population: Are Australian patients missing out?. Nephrology 0:0, pages 070712161837003-???.
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S. Susan Hedayati. (2006) HEMATOLOGY: ISSUES IN THE DIALYSIS PATIENT: Dialysis-Related Carnitine Disorder. Seminars in Dialysis 19:4, pages 323-328.
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Allan M. Evans, Randall J. Faull, Roger L. Nation, Shilpanjali Prasad, Tony Elias, Stephanie E. Reuter & Gianfranco Fornasini. (2004) Impact of hemodialysis on endogenous plasma and muscle carnitine levels in patients with end-stage renal disease. Kidney International 66:4, pages 1527-1534.
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Drukker, Parsons & MaherW. H. Hörl. 2004. Replacement of Renal Function by Dialysis. Replacement of Renal Function by Dialysis 927 963 .
Brent Miller & Suhail Ahmad. (2003) A review of the impact of l-carnitine therapy on patient functionality in maintenance hemodialysis. American Journal of Kidney Diseases 41, pages S44-S48.
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Allan Evans. (2003) Dialysis-related carnitine disorder and levocarnitine pharmacology. American Journal of Kidney Diseases 41, pages S13-S26.
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Jean-Marc Hurot, Michel Cucherat, Margaret Haugh & Denis Fouque. (2002) Effects of l-Carnitine Supplementation in Maintenance Hemodialysis Patients: A Systematic Review. Journal of the American Society of Nephrology 13:3, pages 708-714.
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Suhail Ahmad. (2001) L‐Carnitine in Dialysis Patients. Seminars in Dialysis 14:3, pages 209-217.
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Eric P. Brass, Sharon Adler, Kathy E. Sietsema, William R. Hiatt, Anthony M. Orlando, Antonino Amato & CHIEF Investigators. (2001) Intravenous l-carnitine increases plasma carnitine, reducesfatigue, and may preserve exercise capacity in hemodialysis patients. American Journal of Kidney Diseases 37:5, pages 1018-1028.
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. (2000) I. Adult guidelines. American Journal of Kidney Diseases 35:6, pages s17-s104.
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Sophia Georgala, Kleopatra H. Schulpis, Catherina Georgala & Timos Michas. (2006) L‐carnitine supplementation in patients with cystic acne on isotretinoin therapy★. Journal of the European Academy of Dermatology and Venereology 13:3, pages 205-209.
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Stefan Thomas, Frank-Peter Fischer, Thomas Mettang, Christiane Pauli-Magnus, Jochen Weber & Ulrich Kuhlmann. (1999) Effects of L-carnitine on leukocyte function and viability in hemodialysis patients: A double-blind randomized trial. American Journal of Kidney Diseases 34:4, pages 678-687.
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M. Monti. 1999. From Macromolecules to Man. From Macromolecules to Man 657 710 .
J H Walter. (1996) L-Carnitine.. Archives of Disease in Childhood 74:6, pages 475-478.
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Dumitru Constantin-Teodosiu, David P.J. Kirby, Anthony H. Short, Richard P. Burden, Anthony G. Morgan & Paul L. Greenhaff. (1996) Free and esterified carnitine in continuous ambulatory peritoneal dialysis patients. Kidney International 49:1, pages 158-162.
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Eric P. Brass & William R. Hiatt. (1994) Carnitine metabolism during exercise. Life Sciences 54:19, pages 1383-1393.
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O. Boulat, Béatrice Janin, P. Francioli & C. Bachmann. (1993) Plasma Carnitines: Reference Values in an Ambulatory Population. Clinical Chemistry and Laboratory Medicine 31:9.
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William R. Hiatt, Brian J. Koziol, Joseph I. Shapiro & Eric P. Brass. (1992) Carnitine metabolism during exercise in patients on chronic hemodialysis. Kidney International 41:6, pages 1613-1619.
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Thomas A. Golper & Suhail Ahmad. (2007) L‐Carnitine Administration to Hemodialysis Patients: Has Its Time Come?. Seminars in Dialysis 5:2, pages 94-98.
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A. Wennberg, A. Hyltander, Å. Sjöberg, B. Arfvidsson, R. Sandström, I. Wickström & K. Lundholm. (1992) Prevalence of carnitine depletion in critically ill patients with undernutrition. Metabolism 41:2, pages 165-171.
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N. BazilinskiG. Dunea. (2018) Carnitine: An Overview. The International Journal of Artificial Organs 13:11, pages 720-722.
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M. Soop, E. Forsberg, A. Thörne, G. Cederblad & J. Wahren. (1990) The effect of carnitine supplementation on carnitine balance in patients with persistent post-operative infection. Clinical Nutrition 9:4, pages 195-205.
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Paul S. Kurtin. (2007) Carnitine Metabolism and Usage in Chronic Dialysis Patients. Seminars in Dialysis 3:3, pages 166-170.
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C. Wanner, P. Schollmeyer & W.H. Hörl. (1988) Serum carnitine levels and carnitine esters of patients after kidney transplantation: Role of immunosuppression. Metabolism 37:3, pages 263-267.
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S Rodriguez-Segade, C Alonso De La Peña, M Paz, D Novoa, R Romero, V Arcocha & R Del Rio. (2016) Carnitine Concentrations in Dialysed and Undialysed Patients with Chronic Renal Insufficiency. Annals of Clinical Biochemistry: International Journal of Laboratory Medicine 23:6, pages 671-675.
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S. Rodriguez-Segade, C.Alonso de la Peña, J.M. Paz, D. Novoa, V. Arcocha, R. Romero & R. Del Rio. (1986) Carnitine deficiency in haemodialysed patients. Clinica Chimica Acta 159:3, pages 249-256.
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Barry S. Kendler. (1986) Carnitine: An overview of its role in preventive medicine. Preventive Medicine 15:4, pages 373-390.
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C. Wanner & W. H. Hörl. (1986) Potential role of carnitine in patients with renal insufficiency. Klinische Wochenschrift 64:13, pages 579-586.
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