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Scandinavian Journal of Clinical and Laboratory Investigation Volume 45, 1985 - Issue 3
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Original Article

Carnitine and left ventricular function in haemodialysis patients

Birger Fagher Department of Internal Medicine, University Hospital, Lund, Sweden
,
Gitten Cederblad Department of Clinical Nutrition, Sahlgren's Hospital, University of Gothenburg, Sweden
,
Mario Monti Department of Internal Medicine, University Hospital, Lund, Sweden
,
Lars Olsson Department of Cardiology, University Hospital, Lund, Sweden
,
Britt Rasmussen Department of Cardiology, University Hospital, Lund, Sweden
&
Hans Thysell Department of Nephrology, University Hospital, Lund, Sweden
Pages 193-198 | Received 13 Jun 1984, Accepted 02 Oct 1984, Published online: 08 Jul 2009

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G. F. Romagnoli, A. Naso, G. Carraro & V. Lidestri. (2002) Beneficial Effects of L-Carnitine in Dialysis Patients with Impaired Left Ventricular Function: An Observational Study. Current Medical Research and Opinion 18:3, pages 172-175.
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Birger Fagher, Mario Monti, Peter Nilsson-Ehle & Hans Thysell. (1987) Reduced thermogenesis in muscle and disturbed lipoprotein metabolism in relation to thyroid function in haemodialysis patients. Scandinavian Journal of Clinical and Laboratory Investigation 47:1, pages 91-97.
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Articles from other publishers (37)

Norihiro Nishioka, Yan Luo, Takuya Taniguchi, Tsuyoshi Ohnishi, Miho Kimachi, Roland CK Ng & Norio Watanabe. (2022) Carnitine supplements for people with chronic kidney disease requiring dialysis. Cochrane Database of Systematic Reviews 2022:12.
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Nikayla Patel, Muhammad Magdi Yaqoob & Dunja Aksentijevic. (2022) Cardiac metabolic remodelling in chronic kidney disease. Nature Reviews Nephrology 18:8, pages 524-537.
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Api Chewcharat, Pol Chewcharat, Weitao Liu, Jacqueline Cellini, Elizabeth A. Phipps, Jill A. Melendez Young & Sagar U. Nigwekar. (2022) The effect of levocarnitine supplementation on dialysis-related hypotension: A systematic review, meta-analysis, and trial sequential analysis. PLOS ONE 17:7, pages e0271307.
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Norihiro Nishioka, Yan Luo, Takuya Taniguchi, Tsuyoshi Ohnishi, Miho Kimachi, Roland CK Ng & Norio Watanabe. (2020) Carnitine supplements for people with chronic kidney disease requiring dialysis. Cochrane Database of Systematic Reviews.
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Junko Naito, Hiroshige Ohashi, Michiya Ohno, Masafumi Sugiyama, Kazuyoshi Hayakawa, Akihisa Kunishima, Nobuyuki Takada, Tatsuya Kariya, Koshi Goto, Hisato Takatsu, Toshiki Ohira, Koji Nakahara, Ichijiro Murata, Shingo Minatoguchi, Gakuro Yoshida, Hiroyuki Okura & Shinya Minatoguchi. (2019) Long-Term Levocarnitine Ameliorates Left Ventricular Diastolic as Well as Systolic Dysfunction in Hemodialysis Patients　― Multi-Center Study ―. Circulation Reports 1:11, pages 508-516.
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Takashi Maruyama & Masanori Abe. (2018) Effects of Levocarnitine Treatment on the Cardiac Function in Hemodialysis Patients. Internal Medicine 57:24, pages 3503-3505.
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Zhi-Cheng Jing, Bing-Xiang Wu, Jian-Qiang Peng, Xin-Li Li, Lei Pan, Shui-Ping Zhao, Dong-Ye Li, Zai-Xin Yu, Jian-Bin Gong, Qing-Yan Zhao, Jia-Ning Cao, Guo-Tai Sheng, Jue Li, Benjamin Xiaoyi Li, Su Jiang, Chaofan Liang, Erika Salvi & Valentina Carubelli. (2016) Effect of intravenous l-carnitine in Chinese patients with chronic heart failure. European Heart Journal Supplements 18:suppl A, pages A27-A36.
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Terumi Higuchi, Masanori Abe, Toshio Yamazaki, Erina Okawa, Hideyuki Ando, Sunao Hotta, Osamu Oikawa, Fumito Kikuchi, Kazuyoshi Okada & Masayoshi Soma. (2016) Levocarnitine Improves Cardiac Function in Hemodialysis Patients With Left Ventricular Hypertrophy: A Randomized Controlled Trial. American Journal of Kidney Diseases 67:2, pages 260-270.
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Yizhi Chen, Manuela Abbate, Li Tang, Guangyan Cai, Zhixiang Gong, Ribao Wei, Jianhui Zhou & Xiangmei Chen. (2014) l-Carnitine supplementation for adults with end-stage kidney disease requiring maintenance hemodialysis: a systematic review and meta-analysis. The American Journal of Clinical Nutrition 99:2, pages 408-422.
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Kristen Sgambat, Lowell Frank, Ahmad Ellini, Craig Sable & Asha Moudgil. (2012) Carnitine supplementation improves cardiac strain rate in children on chronic hemodialysis. Pediatric Nephrology 27:8, pages 1381-1387.
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Lorenzo A. Calò, Ugo Vertolli, Paul A. Davis & Vincenzo Savica. (2012) L carnitine in hemodialysis patients . Hemodialysis International 16:3, pages 428-434.
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Seung-Jung Kim. (2012) The Effects of Carnitine Supplementation in Hemodialysis Patients. The Ewha Medical Journal 35:2, pages 89.
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Alaa A. Sabry, Osama Ghaith, Tarek Medhat, Shahir K. George & Eid E. Elshafey. (2009) Is there a Role for Oral L-Carnitine Therapy in Anemia and Cardiac Dysfunction Management in Egyptian Patients on Maintenance Hemodialysis?. Electronic Journal of General Medicine 6:2, pages 60-68.
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Katherine E. Lynch, Harold I. Feldman, Jesse A. Berlin, James Flory, Christopher G. Rowan & Steven M. Brunelli. (2008) Effects of l-Carnitine on Dialysis-Related Hypotension and Muscle Cramps: A Meta-analysis. American Journal of Kidney Diseases 52:5, pages 962-971.
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Tai Sakurabayashi, Shigeru Miyazaki, Yasuko Yuasa, Shinji Sakai, Masashi Suzuki, Sachio Takahashi & Yoshihei Hirasawa. (2008) L-Carnitine Supplementation Decreases the Left Ventricular Mass in Patients Undergoing Hemodialysis. Circulation Journal 72:6, pages 926-931.
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STEPHANIE E REUTER, RANDALL J FAULL & ALLAN M EVANS. (2007) L-carnitine supplementation in the dialysis population: Are Australian patients missing out?. Nephrology 0:0, pages 070712161837003-???.
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S. Susan Hedayati. (2006) HEMATOLOGY: ISSUES IN THE DIALYSIS PATIENT: Dialysis-Related Carnitine Disorder. Seminars in Dialysis 19:4, pages 323-328.
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Brook Belay, Nora Esteban-Cruciani, Christine A. Walsh & Frederick J. Kaskel. (2005) The use of levo-carnitine in children with renal disease: a review and a call for future studies. Pediatric Nephrology 21:3, pages 308-317.
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Brian Schreiber. (2017) Levocarnitine and Dialysis: A Review. Nutrition in Clinical Practice 20:2, pages 218-243.
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MENOTTI CALVANI, PAOLA BENATTI, ANGELO MANCINELLI, STEFANIA D'IDDIO, VINCENZO GIORDANO, ALEARDO KOVERECH, ANTONINO AMATO & ERIC P. BRASS. (2004) Carnitine Replacement in End-Stage Renal Disease and Hemodialysis. Annals of the New York Academy of Sciences 1033:1, pages 52-66.
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Drukker, Parsons & MaherW. H. Hörl. 2004. Replacement of Renal Function by Dialysis. Replacement of Renal Function by Dialysis 927 963 .
Brian D. Schreiber. (2003) Congestive Heart Failure in Patients with Chronic Kidney Disease and on Dialysis. The American Journal of the Medical Sciences 325:4, pages 179-193.
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Daniel F Pauly & Carl J Pepine. (2003) The role of carnitine in myocardial dysfunction. American Journal of Kidney Diseases 41, pages S35-S43.
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Jean-Marc Hurot, Michel Cucherat, Margaret Haugh & Denis Fouque. (2002) Effects of l-Carnitine Supplementation in Maintenance Hemodialysis Patients: A Systematic Review. Journal of the American Society of Nephrology 13:3, pages 708-714.
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Suhail Ahmad. (2001) L‐Carnitine in Dialysis Patients. Seminars in Dialysis 14:3, pages 209-217.
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. (2000) I. Adult guidelines. American Journal of Kidney Diseases 35:6, pages s17-s104.
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Stefan Thomas, Frank-Peter Fischer, Thomas Mettang, Christiane Pauli-Magnus, Jochen Weber & Ulrich Kuhlmann. (1999) Effects of L-carnitine on leukocyte function and viability in hemodialysis patients: A double-blind randomized trial. American Journal of Kidney Diseases 34:4, pages 678-687.
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REZAN TOPALOǴLU, ALPAY ÇELIKER, ÜMIT SAATÇI, KAMER KLINÇ, AYÇIN BAKKALOǴLU, NESRIN BEşBAS & KÜRSdedilAT TOKEL. (2007) Effect of carnitine supplementation on cardiac function in hemodialyzed children. Pediatrics International 40:1, pages 26-29.
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Thomas A. Golper & Suhail Ahmad. (2007) L‐Carnitine Administration to Hemodialysis Patients: Has Its Time Come?. Seminars in Dialysis 5:2, pages 94-98.
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N. BazilinskiG. Dunea. (2018) Carnitine: An Overview. The International Journal of Artificial Organs 13:11, pages 720-722.
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Suhail Ahmad, H. Thomas Robertson, Thomas A. Golper, Marsha Wolfson, Paul Kurtin, Lois A. Katz, Raimund Hirschberg, Robert Nicora, Donald W. Ashbrook & Joel D. Kopple. (1990) Multicenter trial of L-carnitine in maintenance hemodialysis patients. II. Clinical and biochemical effects. Kidney International 38:5, pages 912-918.
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Paul S. Kurtin. (2007) Carnitine Metabolism and Usage in Chronic Dialysis Patients. Seminars in Dialysis 3:3, pages 166-170.
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Peter Fürst, Anne Glöggler & Claudia Rössle. 1990. New Perspectives in Hemodialysis, Peritoneal Dialysis, Arteriovenous Hemofiltration, and Plasmapheresis. New Perspectives in Hemodialysis, Peritoneal Dialysis, Arteriovenous Hemofiltration, and Plasmapheresis 69 77 .
K. Lundholm, H. Persson & A. Wennberg. (2008) Whole body fat oxidation before and after carnitine supplementation in uremic patients on chronic haemodialysis. Clinical Physiology 8:4, pages 417-426.
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H. R. Scholte, I. E. M. Luyt-Houwen & M. H. M. Vaandrager-Verduin. 1987. Lipid metabolism in the normoxic and ischaemic heart. Lipid metabolism in the normoxic and ischaemic heart 63 73 .
Barry S. Kendler. (1986) Carnitine: An overview of its role in preventive medicine. Preventive Medicine 15:4, pages 373-390.
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C. Wanner & W. H. Hörl. (1986) Potential role of carnitine in patients with renal insufficiency. Klinische Wochenschrift 64:13, pages 579-586.
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