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Scandinavian Journal of Clinical and Laboratory Investigation Volume 51, 1991 - Issue 6
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Original Article

Distribution and elimination of intravenously injected urinary trypsin inhibitor

B-M. Jönsson-Berling Anaesthesiology, Malmo General Hospital, University of Lund, Malmö, Sweden
&
K. Ohlsson Departments of Surgical Pathophysiology, Malmö, Sweden
Pages 549-557 | Received 04 Mar 1991, Accepted 11 Apr 1991, Published online: 08 Jul 2009

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Shizuyo Tsujimura, Kazuyoshi Saito, Shingo Nakayamada & Yoshiya Tanaka. (2005) Human urinary trypsin inhibitor bolus infusion improved severe interstitial pneumonia in mixed connective tissue disease. Modern Rheumatology 15:5, pages 374-380.
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T. Noie, Y. Sugawara, Y. Harihara, T. Takayama, K. Kubota, Y. Ohashi, M. Makuuchi. (2001) Kinetics of Urinary Trypsin Inhibitor in Patients Undergoing Partial Hepatectomy. Scandinavian Journal of Gastroenterology 36:4, pages 410-416.
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L. Axelsson, M. Bergenfeldt & K. Ohlsson. (1995) Studies of the release and turnover of a human neutrophil lipocalin. Scandinavian Journal of Clinical and Laboratory Investigation 55:7, pages 577-588.
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Emad El Maradny, Naohiro Kanayama, Abdul Halim, Kayoko Maehara & Toshihiko Terao. (1994) Urinary trypsin inhibitor may have a protective effect on endothelial cells in preeclampsia. Acta Obstetricia et Gynecologica Scandinavica 73:10, pages 755-757.
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Articles from other publishers (31)

Aric F. Logsdon, Michelle A. Erickson, Melanie J. Herbert, Cassidy Noonan, Brian D. Foresi, Joseph Qiu, Yow-Pin Lim, William A. Banks & Barbara S. Stonestreet. (2023) Inter-alpha inhibitor proteins attenuate lipopolysaccharide-induced blood-brain barrier disruption in neonatal mice. Experimental Neurology 370, pages 114563.
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Stavros Garantziotis. 2023. Hyaluronan. Hyaluronan 99 117 .
Hu Zhenyu, Yuan Qiaoli, Chen Guangxiang & Wang Maohua. (2022) The effect of Ulinastatin on postoperative course in cardiopulmonary bypass patients in Asia: a meta-analysis of randomized controlled trials. Journal of Cardiothoracic Surgery 17:1.
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Louise D. McCullough, Meaghan Roy-O’Reilly, Yun-Ju Lai, Anthony Patrizz, Yan Xu, Juneyoung Lee, Aleah Holmes, Daniel C. Kraushaar, Anjali Chauhan, Lauren H. Sansing, Barbara S. Stonestreet, Liang Zhu, Julia Kofler, Yow-Pin Lim & Venugopal Reddy Venna. (2021) Exogenous inter-α inhibitor proteins prevent cell death and improve ischemic stroke outcomes in mice. Journal of Clinical Investigation 131:17.
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Xuejiao Wei, Xiaoyu Zhu, Lili Jiang, Mengtuan Long & Yujun Du. (2021) Recent research progress on the role of ulinastatin in chronic kidney disease. Nephrology 26:9, pages 708-714.
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Yun-Tai Yao, Neng-Xin Fang, Ding-Hua Liu & Li-Huan Li. (2020) Ulinastatin reduces postoperative bleeding and red blood cell transfusion in patients undergoing cardiac surgery. Medicine 99:7, pages e19184.
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Ka-Young Rhee, Tae-Yun Sung, Ju Deok Kim, Hyun Kang, Nazri Mohamad & Tae-Yop Kim. (2018) High-dose ulinastatin improves postoperative oxygenation in patients undergoing aortic valve surgery with cardiopulmonary bypass: A retrospective study. Journal of International Medical Research 46:3, pages 1238-1248.
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Su Jin Kim, Dae Hwan Kang, Hyung Wook Kim, Cheol Woong Choi, Su Bum Park, Byeong Jun Song & Hyeong Seok Nam. (2016) A Randomized Comparative Study of 24- and 6-Hour Infusion of Nafamostat Mesilate for the Prevention of Post–Endoscopic Retrograde Cholangiopancreatography Pancreatitis. Pancreas 45:8, pages 1179-1183.
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Sarjana S. Atal & Shubham Atal. (2016) Ulinastatin – a newer potential therapeutic option for multiple organ dysfunction syndrome. Journal of Basic and Clinical Physiology and Pharmacology 27:2, pages 91-99.
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Yan Qiu, Jing Lin, Yang Yang, Jing Zhou, Li-Na Gong, Zhen Qin & Lei Du. (2015) Lack of Efficacy of Ulinastatin Therapy During Cardiopulmonary Bypass Surgery. Chinese Medical Journal 128:23, pages 3138-3142.
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Peng F Luo, Yu Ren, Ya-Lin Liu & Zhao-Fan Xia. 1996. Cochrane Database of Systematic Reviews. Cochrane Database of Systematic Reviews.
B. Joseph Elmunzer. (2014) Pharmacologic prevention of pancreatitis after endoscopic retrograde cholangiopancreatography: Present and future. Techniques in Gastrointestinal Endoscopy 16:4, pages 169-174.
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Ming Feng, Yaqing Shu, Yu Yang, Xueping Zheng, Rui Li, Yuge Wang, Yongqiang Dai, Wei Qiu, Zhengqi Lu & Xueqiang Hu. (2014) Ulinastatin attenuates experimental autoimmune encephalomyelitis by enhancing anti-inflammatory responses. Neurochemistry International 64, pages 64-72.
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Jieun SongJungmin ParkJee-Young KimJoo-Duck KimWoon-Seok KangHasmizy Bin MuhammadMi-Young KwonSeong-Hyop KimTae Gyoon YoonTae-Yop KimJin Woo Chung. (2013) Effect of ulinastatin on perioperative organ function and systemic inflammatory reaction during cardiac surgery: a randomized double-blinded study. Korean Journal of Anesthesiology 64:4, pages 334.
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Na-Young KimJae-Kwang ShimSeo-Ouk BangJee-Suk SimJong-Wook SongYoung-Lan Kwak. (2013) Effects of ulinastatin on coagulation in high-risk patients undergoing off-pump coronary artery bypass graft surgery. Korean Journal of Anesthesiology 64:2, pages 105.
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Peng F Luo, Yu Ren, Ya-Lin Liu & Zhao-Fan Xia. 1996. Cochrane Database of Systematic Reviews. Cochrane Database of Systematic Reviews.
F. Donnellan & Michael F. Byrne. (2012) Prevention of Post-ERCP Pancreatitis. Gastroenterology Research and Practice 2012, pages 1-12.
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Jin Young LeeJi Young LeeJin Young ChonHo Sik MoonSung Jin Hong. (2010) The effect of ulinastatin on hemostasis in major orthopedic surgery. Korean Journal of Anesthesiology 58:1, pages 25.
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Ji Won Yoo, Ji Kon Ryu, Sang Hyub Lee, Sang Myung Woo, Joo Kyung Park, Won Jae Yoon, Jun Kyu Lee, Kwang Hyuck Lee, Jin-Hyeok Hwang, Yong-Tae Kim & Yong Bum Yoon. (2008) Preventive Effects of Ulinastatin on Post-Endoscopic Retrograde Cholangiopancreatography Pancreatitis in High-Risk Patients. Pancreas 37:4, pages 366-370.
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Hirofumi Fujishiro, Kyoichi Adachi, Tomonori Imaoka, Tomoyuki Hashimoto, Naruaki Kohge, Nobuyuki Moriyama, Hiroshi Suetsugu, Kousaku Kawashima, Yoshinori Komazawa, Norihisa Ishimura, Shunji Ishihara, Yuji Amano & Yoshikazu Kinoshita. (2006) Ulinastatin shows preventive effect on post-endoscopic retrograde cholangiopancreatography pancreatitis in a multicenter prospective randomized study. Journal of Gastroenterology and Hepatology 21:6, pages 1065-1069.
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Kazuhiro Nakanishi, Shinhiro Takeda, Atsuhiro Sakamoto & Akira Kitamura. (2006) Effects of ulinastatin treatment on the cardiopulmonary bypass-induced hemodynamic instability and pulmonary dysfunction. Critical Care Medicine 34:5, pages 1351-1357.
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Yuhji Saitoh. (2005) Drugs to facilitate recovery of neuromuscular blockade and muscle strength. Journal of Anesthesia 19:4, pages 302-308.
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LISHENG ZHUO, NAOKI ITANO, TSUNEMASA NONOGAKI, LI SHEN, JIWEN WU, HIDETO WATANABE & KOJI KIMATA. 2004. Chemistry and Biology of Hyaluronan. Chemistry and Biology of Hyaluronan 205 222 .
Keiichi Sakai, Hiroshi Okudera & Kazuhiro Hongo. (2003) Significant elevation of urinary trypsin inhibitor in patients with brain contusion - a preliminary report. Journal of Clinical Neuroscience 10:6, pages 677-679.
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Charlotte Mizon, Frank Piva, Viviane Queyrel, Malika Balduyck, Eric Hachulla & Jacques Mizon. (2002) Urinary Bikunin Determination Provides Insight into Proteinase/Proteinase Inhibitor Imbalance in Patients with Inflammatory Diseases. Clinical Chemistry and Laboratory Medicine 40:6.
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Tomoki Nishiyama & Kazuo Hanaoka. (2001) Do the effects of a protease inhibitor, ulinastatin, on elastase release by blood transfusion depend on interleukin 6?. Critical Care Medicine 29:11, pages 2106-2110.
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Erik Fries & Anna M Blom. (2000) Bikunin — not just a plasma proteinase inhibitor. The International Journal of Biochemistry & Cell Biology 32:2, pages 125-137.
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Yuhji Saitoh, Yoshitaka Fujii & Tsutomu Oshima. (1999) The Ulinastatin-Induced Effect on Neuromuscular Block Caused by Vecuronium [RETRACTED]. Anesthesia & Analgesia 89:6, pages 1565.
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MERCÉ JOURDAIN, ODILE CARRETTE, ANTOINE TOURNOYS, FRANÇOIS FOURRIER, CHARLOTTE MIZON, JACQUES MANGALABOYI, JENNY GOUDEMAND, JACQUES MIZON & CLAUDE CHOPIN. (1997) Effects of Inter- α -inhibitor in Experimental Endotoxic Shock and Disseminated Intravascular Coagulation. American Journal of Respiratory and Critical Care Medicine 156:6, pages 1825-1833.
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Masanori Nakakuki, Fumiaki Yamasaki, Tomoaki Shinkawa, Mami Kudo, Mitsutoshi Watanabe & Masahiro Mizota. (1996) Protective effect of human ulinastatin against gentamicin-induced acute renal failure in rats. Canadian Journal of Physiology and Pharmacology 74:1, pages 104-111.
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Anna Stota, Mats Sjöquist, Mats Wolgast, James Alston-Smith & Erik Fries. (1994) Bikunin in Rat Plasma, Lymph and Bile. Biological Chemistry Hoppe-Seyler 375:2, pages 127-134.
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