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Original Article

Long-term supplementation with n-3 fatty acids, I: effect on blood lipids, haemostasis and blood pressure

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Pages 221-228 | Received 05 Apr 1991, Accepted 03 Nov 1991, Published online: 08 Jul 2009

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Helga Gerster. (1995) n-3 Fish Oil Polyunsaturated Fatty Acids and Bleeding. Journal of Nutritional & Environmental Medicine 5:3, pages 281-296.
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E. Turley & J. J. Strain. (1993) Fish oils, eicosanoid biosynthesis and cardiovascular disease: An overview. International Journal of Food Sciences and Nutrition 44:2, pages 145-152.
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Olle Haglund. (1993) Effects of Fish Oil on Risk Factors for Cardiovascular Disease. Upsala Journal of Medical Sciences 98:2, pages 89-148.
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E. B. Schmidt, K. Varming, J. O. Pedersen, H.-H. Lervang, N. Grunnet, C. Jersild & J. Dyerberg. (1992) Long-term supplementation with n-3 fatty acids, II: effect on neutrophil and monocyte chemotaxis. Scandinavian Journal of Clinical and Laboratory Investigation 52:3, pages 229-236.
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Articles from other publishers (37)

Stephanie Jeansen, Renger F. Witkamp, Jossie A. Garthoff, Ardy van Helvoort & Philip C. Calder. (2018) Fish oil LC-PUFAs do not affect blood coagulation parameters and bleeding manifestations: Analysis of 8 clinical studies with selected patient groups on omega-3-enriched medical nutrition. Clinical Nutrition 37:3, pages 948-957.
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John Alfred Carr. (2018) Role of Fish Oil in Post - Cardiotomy Bleeding: A Summary of the Basic Science and Clinical Trials. The Annals of Thoracic Surgery 105:5, pages 1563-1567.
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Janice I. Harland. 2016. Functional Dietary Lipids. Functional Dietary Lipids 249 285 .
F. J. García-Alonso, V. Jorge-Vidal, G. Ros & M. J. Periago. (2011) Effect of consumption of tomato juice enriched with n-3 polyunsaturated fatty acids on the lipid profile, antioxidant biomarker status, and cardiovascular disease risk in healthy women. European Journal of Nutrition 51:4, pages 415-424.
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. (2009) Scientific Opinion on the substantiation of health claims related to EPA, DHA, DPA and maintenance of normal blood pressure (ID 502), maintenance of normal HDL-cholesterol concentrations (ID 515), maintenance of normal (fasting) blood concentrations of tr. EFSA Journal 7:10, pages 1263.
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Kathryn R. Mahaffey, Robert P. Clickner & Rebecca A. Jeffries. (2008) Methylmercury and omega-3 fatty acids: Co-occurrence of dietary sources with emphasis on fish and shellfish. Environmental Research 107:1, pages 20-29.
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Priscila de Mattos Machado Andrade, Beatriz Gonçalves Ribeiro & Maria das Graças Tavares do Carmo. (2006) Suplementação de ácidos graxos ômega 3 em atletas de competição: impacto nos mediadores bioquímicos relacionados com o metabolismo lipídico. Revista Brasileira de Medicina do Esporte 12:6, pages 339-344.
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Birthe M Rasmussen, Bengt Vessby, Matti Uusitupa, Lars Berglund, Eva Pedersen, Gabrielle Riccardi, Angela A Rivellese, Linda Tapsell & Kjeld Hermansen. (2006) Effects of dietary saturated, monounsaturated, and n−3 fatty acids on blood pressure in healthy subjects. The American Journal of Clinical Nutrition 83:2, pages 221-226.
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Kaeng W. Lee, Andrew D. Blann & Gregory Y.H. Lip. (2006) Effects of omega-3 polyunsaturated fatty acids on plasma indices of thrombogenesis and inflammation in patients post-myocardial infarction. Thrombosis Research 118:3, pages 305-312.
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. (2005) Opinion of the Scientific Panel on Dietetic products, nutrition and allergies [NDA] related to nutrition claims concerning omega-3 fatty acids, monounsaturated fat, polyunsaturated fat and unsaturated fat. EFSA Journal 3:8, pages 253.
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Yasuyuki Nakamura, Hirotsugu Ueshima, Tomonori Okamura, Takashi Kadowaki, Takehito Hayakawa, Yoshikuni Kita, Shinji Tamaki & Akira Okayama. (2005) Association between fish consumption and all-cause and cause-specific mortality in Japan: NIPPON DATA80, 1980–99. The American Journal of Medicine 118:3, pages 239-245.
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Robert Kroes, Ernst J. Schaefer, Robert A. Squire & Gary M. Williams. (2003) A review of the safety of DHA45-oil. Food and Chemical Toxicology 41:11, pages 1433-1446.
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Niels Svaneborg, Steen D Kristensen, Lene M Hansen, Inge Büllow, Steen E Husted & Erik B Schmidt. (2002) The acute and short-time effect of supplementation with the combination of n−3 fatty acids and acetylsalicylic acid on platelet function and plasma lipids. Thrombosis Research 105:4, pages 311-316.
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Ralf Junker, Birgitta Pieke, Helmut Schulte, Roch Nofer, Margitta Neufeld, Gerd Assmann & Ursel Wahrburg. (2001) Changes in Hemostasis During Treatment of Hypertriglyceridemia With a Diet Rich in Monounsaturated and n−3 Polyunsaturated Fatty Acids in Comparison With a Low-Fat Diet. Thrombosis Research 101:5, pages 355-366.
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Siobhán Higgins, Yvonne L. Carroll, Sinéad N. McCarthy, Bernice M. Corridan, Helen M. Roche, Julie M. W. Wallace, Nora M. O'Brien & Patrick A. Morrissey. (2007) Susceptibility of LDL to oxidative modification in healthy volunteers supplemented with low doses of n -3 polyunsaturated fatty acids . British Journal of Nutrition 85:1, pages 23-31.
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John-Bjarne Hansen, Sameline Grimsgaard, Arne Nordøy & Kaare H. Bønaa. (2000) Dietary Supplementation with Highly Purified Eicosapentaenoic Acid and Docosahexaenoic Acid Does Not Influence PAI-1 Activity. Thrombosis Research 98:2, pages 123-132.
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Helen M. Roche & Michael J. Gibney. (1999) Long-chain n-3 polyunsaturated fatty acids and triacylglycerol metabolism in the postprandial state. Lipids 34:S1, pages S259-S265.
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Armand ChristopheC Phan, B-C Mortimer & T Redgrave. 1998. Structural Modified Food Fats. Structural Modified Food Fats 207 228 .
B. Ponsard, I. Durot, A. Fournier, F. Oudot, P. Athias & A. Grynberg. (1998) Long-chain polyunsaturated fatty acids influence both β- and α-adrenergic function of rat cardiomyocytes. Journal of the American Oil Chemists' Society 75:2, pages 247-254.
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Peter MarckmannElse-Marie BladbjergJørgen Jespersen. (1997) Dietary Fish Oil (4 g Daily) and Cardiovascular Risk Markers in Healthy Men. Arteriosclerosis, Thrombosis, and Vascular Biology 17:12, pages 3384-3391.
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M. Mutanen. (1997) Cis-unsaturated fatty acids and platelet function. Prostaglandins, Leukotrienes and Essential Fatty Acids 57:4-5, pages 403-410.
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J. A. Lovegrove, C. N. Brooks, M. C. Murphy, B. J. Gould & C. M. Williams. (2007) Use of manufactured foods enriched with fish oils as a means of increasing long-chain n −3 polyunsaturated fatty acid intake . British Journal of Nutrition 78:2, pages 223-236.
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HR Knapp. (1997) Dietary fatty acids in human thrombosis and hemostasis. The American Journal of Clinical Nutrition 65:5, pages 1687S-1698S.
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NW Schoene. (1997) Design criteria: tests used to assess platelet function. The American Journal of Clinical Nutrition 65:5, pages 1665S-1668S.
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H. H Vorster, J. H Cummings & F. J Veldman. (2007) Diet and haemostasis: time for nutrition science to get more involved. British Journal of Nutrition 77:5, pages 671-684.
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N. Yahia & T. A. B. Sanders. (2008) The influence of dietary fat on postprandial lipaemia and factor VII coagulant activity in human subjects. Proceedings of the Nutrition Society 56:1B, pages 489-496.
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Hester H. Vorster, John H. Cummings & Johann C. Jerling. (2007) Diet and haemostatic processes. Nutrition Research Reviews 10:1, pages 115-135.
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JoséManuel Silva, Ivone Souza, Rosa Silva, Paula Tavares, Frederico Teixeira & Políbio Serra Sliva. (1996) The triglyceride lowering effect of fish oils is affected by fish consumption. International Journal of Cardiology 57:1, pages 75-80.
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Carsten Otto, Michael M. Ritter, Andreas C. Soennichsen, Peter Schwandt & Werner O. Richter. (1996) Effects of n-3 fatty acids and fenofibrate on lipid and hemorrheological parameters in familial dysbetalipoproteinemia and familial hypertriglyceridemia. Metabolism 45:10, pages 1305-1311.
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Jannie Dalby Salvig, Sjúrdur F. Olsen & Niels Jsrgen Secher. (2005) Effects of fish oil supplementation in late pregnancy on blood pressure: a randomised controlled trial. BJOG: An International Journal of Obstetrics & Gynaecology 103:6, pages 529-533.
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S. ENDRES, R. DE CATERINA, E. B. SCHMIDT & S. D. KRISTENSENJ. (2008) n‐3 Polyunsaturated fatty acids: update 1995. European Journal of Clinical Investigation 25:9, pages 629-638.
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Laurence A. Harker & Stephen R. Hanson. (1994) 5 Platelet factors predisposing to arterial thrombosis. Baillière's Clinical Haematology 7:3, pages 499-522.
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Håvard H. Mundal, Helle M. Meltzer & Ivar Aursnes. (1994) Bleeding times related to serum triglyceride levels in healthy young adults. Thrombosis Research 75:3, pages 285-291.
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Olle Haglund, Jawahar L. Mehta & Tom Saldeen. (1994) Effects of fish oil on some parameters of fibrinolysis and lipoprotein(a) in healthy subjects. The American Journal of Cardiology 74:2, pages 189-192.
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Erik Berg Schmidt, Jørn Munkhof Møller, Niels Svaneborg & Jørn Dyerberg. (2012) Safety Aspects of Fish Oils. Drug Investigation 7:4, pages 215-220.
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G.N. Petrukhina, V.H. Gandel, V.A. Makarov & G.V. Bashkov. (1994) Changes in acute release of t-PA after chronic administration of n-3 polyunsaturated fatty acids into rabbits. Fibrinolysis 8, pages 53-54.
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P. Marckmann & J. Jespersen. (1994) Introduction to diet and endogenous fibrinolysis. Fibrinolysis 8, pages 37-40.
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