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Original Article

Acetaldehyde adducts of proteins: Diagnostic and pathogenic implications in diseases caused by excessive alcohol consumption

Pages 45-54 | Published online: 08 Jul 2009

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Fatemeh Bootorabi, Janne Jänis, Vesa P. Hytönen, Jarkko Valjakka, Marianne Kuuslahti, Daniela Vullo, Onni Niemelä, Claudiu T. Supuran & Seppo Parkkila. (2011) Acetaldehyde-derived modifications on cytosolic human carbonic anhydrases. Journal of Enzyme Inhibition and Medicinal Chemistry 26:6, pages 862-870.
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Mikko Salaspuro. (1996) Bacteriocolonic Pathway for Ethanol Oxidation: Characteristics and Implications. Annals of Medicine 28:3, pages 195-200.
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Articles from other publishers (21)

Sana Waris, Safia Habib, Irfan Qadir Tantry, Rizwan Hasan Khan, Riaz Mahmood & Asif Ali. (2018) Acetaldehyde-induced structural and conformational alterations in human immunoglobulin G: A physicochemical and multi-spectroscopic study. International Journal of Biological Macromolecules 113, pages 701-710.
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C Ju, E Phillips, M.P. Holt, Y.R. Gao & C. Lammert. 2018. Comprehensive Toxicology. Comprehensive Toxicology 346 367 .
Udo Bonnet, Claudia Selle, Katrin Isbruch & Katrin Isbruch. (2016) Recurrent purpura due to alcohol-related Schamberg’s disease and its association with serum immunoglobulins: a longitudinal observation of a heavy drinker. Journal of Medical Case Reports 10:1.
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Derrick T. Antoniak, Michael J. Duryee, Ted R. Mikuls, Geoffrey M. Thiele & Daniel R. Anderson. (2015) Aldehyde-modified proteins as mediators of early inflammation in atherosclerotic disease. Free Radical Biology and Medicine 89, pages 409-418.
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Arthur I. Cederbaum. (2012) Alcohol Metabolism. Clinics in Liver Disease 16:4, pages 667-685.
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Christian Solís-Calero, Joaquín Ortega-Castro, Alfonso Hernández-Laguna & Francisco Muñoz. (2012) A comparative DFT study of the Schiff base formation from acetaldehyde and butylamine, glycine and phosphatidylethanolamine. Theoretical Chemistry Accounts 131:9.
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Nympha B. D’Souza El‐Guindy, Elizabeth J. Kovacs, Philippe De Witte, Claudia Spies, John M. Littleton, Willem J. S. De Villiers, Amanda J. Lott, Timothy P. Plackett, Nadine Lanzke & Gary G. Meadows. (2010) Laboratory Models Available to Study Alcohol‐Induced Organ Damage and Immune Variations: Choosing the Appropriate Model. Alcoholism: Clinical and Experimental Research 34:9, pages 1489-1511.
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M.P. Holt & C. Ju. 2010. Comprehensive Toxicology. Comprehensive Toxicology 275 293 .
Kusum K. Kharbanda, Mark E. Mailliard, Cheryl R. Baldwin, Michael F. Sorrell & Dean J. Tuma. (2007) Accumulation of proteins bearing atypical isoaspartyl residues in livers of alcohol-fed rats is prevented by betaine administration: Effects on protein-l-isoaspartyl methyltransferase activity. Journal of Hepatology 46:6, pages 1119-1125.
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Robert Swift. (2003) Direct measurement of alcohol and its metabolites. Addiction 98, pages 73-80.
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Yeldur P. Venkatesh & Venkatesh L. Hegde. (2003) A hypothesis for the mechanism of immediate hypersensitivity to mannitol. Allergology International 52:3, pages 165-170.
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Dharam Agarwal & Helmut SeitzMikko Salaspuro. 2001. Alcohol in Health and Disease. Alcohol in Health and Disease 67 85 .
Simon Worrall, Peter J. Richardson & Victor R. Preedy. (2006) Experimental heart muscle damage in alcohol feeding is associated with increased amounts of reduced‐ and unreduced‐acetaldehyde and malondialdehyde–acetaldehyde protein adducts. Addiction Biology 5:4, pages 421-427.
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Simon Worrall, Vinood Patel, Peter Richardson, Michael Dunn & Victor Preedy. 2000. Alcohol and Coffee Use in the Aging. Alcohol and Coffee Use in the Aging 41 56 .
S. E. Hazelett, R. A. Liebelt, W. J. Brown, V. Androulakakis, D. Jarjoura & E. B. TruittJr.Jr.. (2006) Evaluation of Acetaldehyde‐Modified Hemoglobin and Other Markers of Chronic Heavy Alcohol Use: Effects of Gender and Hemoglobin Concentration. Alcoholism: Clinical and Experimental Research 22:8, pages 1813-1819.
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Geoffrey M. Thiele, Dean J. Tuma, Monte S. Willis, Jacqueline A. Miller, Thomas L. McDonald, Michael F. Sorrell & Lynell W. Klassen. (2006) Soluble Proteins Modified with Acetaldehyde and Malondialdehyde Are Immunogenic in the Absence of Adjuvant. Alcoholism: Clinical and Experimental Research 22:8, pages 1731-1739.
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Katja Viitala, Kaija Lähdesmäki & Onni Niemelä. (1998) Comparison of the Axis %CDT TIA and the CDTect method as laboratory tests of alcohol abuse. Clinical Chemistry 44:6, pages 1209-1215.
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S C Rowat. (1998) Integrated defense system overlaps as a disease model: with examples for multiple chemical sensitivity.. Environmental Health Perspectives 106:suppl 1, pages 85-109.
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Neil R. Pumford and & N. Christine Halmes. (1997) PROTEIN TARGETS OF XENOBIOTIC REACTIVE INTERMEDIATES. Annual Review of Pharmacology and Toxicology 37:1, pages 91-117.
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Arthur S. Brecher, Alan P. Koterba & Michael H. Basista. (1996) Coagulation protein function. IV. Effect of acetaldehyde upon factor X and factor Xa, the proteins at the gateway to the common coagulation pathway. Alcohol 13:6, pages 539-545.
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Dita Jelínková, Zdeněk Deyl, Ivan Mikšík & Franco Tagliaro. (1995) Capillary electrophoresis of hair proteins modified by alcohol intake in laboratory rats. Journal of Chromatography A 709:1, pages 111-119.
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