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Original Article

Frequency of hyperprolactinaemia due to large molecular weight prolactin (150-170 kD PRL)

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Pages 139-147 | Received 22 Mar 1994, Accepted 28 Nov 1994, Published online: 08 Jul 2009

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Read on this site (2)

Juan J. Espinós, Cristina Vanrell, Ignasi Gich, Eulalia Urgell & Joaquim Calaf. (2017) Pituitary response profile following metoclopramide administration in women with different forms of hyperprolactinemia. Gynecological Endocrinology 33:2, pages 148-151.
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C. Theunissen, J. De Schepper, J. Schiettecatte, P. Verdood, E.L. Hooghe-Peeters & B. Velkeniers. (2005) MACROPROLACTINEMIA: CLINICAL SIGNIFICANCE AND CHARACTERIZATION OF THE CONDITION. Acta Clinica Belgica 60:4, pages 190-197.
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Articles from other publishers (80)

Lokesh Kumar Sharma, Deep Dutta, Neera Sharma, Bindu Kulshreshtha, Sandhya Lal & Ritika Sethi. (2021) Prevalence of Macroprolactinemia in People Detected to Have Hyperprolactinemia. Journal of Laboratory Physicians 13:04, pages 353-357.
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Khanh Quynh N. Nguyen, Rachel H. Langevin, Michael J. McPhaul & Ibrahim A. Hashim. (2021) Circulating macroprolactin exhibits molecular heterogeneity and is not exclusively an antibody complex. Clinica Chimica Acta 514, pages 90-95.
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Robert Krysiak, Witold Szkróbka & Bogusław Okopień. (2019) Cardiometabolic Risk Factors in Men with Elevated Macroprolactin Content: A Pilot Study. Experimental and Clinical Endocrinology & Diabetes 129:01, pages 7-13.
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Chao Yu, Fei Fan, Siqi Hu, Lingxin Meng, Dong Xu, Juan Wang, Lu Chen, Jingrui Liu, Ying Dong, Yifan Lu, Min Shen, Yanhong Zhai & Zheng Cao. (2020) Evaluation of autoantibodies and immunoglobulin G subclasses in women with suspected macroprolactinemia. Journal of Clinical Laboratory Analysis 34:11.
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Juana Serret-Montaya, Jessie N. Zurita-Cruz, Miguel A. Villasís-Keever, Alejandra Aguilar-Kitsu, Claudia del Carmen Zepeda-Martinez, Irving Cruz-Anleu, Beatriz C. Hernández-Hernández, Sara R. Alonso-Flores, Leticia Manuel-Apolinar, Leticia Damasio-Santana, Abigail Hernandez-Cabezza & José C. Romo-Vázquez. (2020) Hyperprolactinemia as a prognostic factor for menstrual disorders in female adolescents with advanced chronic kidney disease. Pediatric Nephrology 35:6, pages 1041-1049.
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Melahat Dirican, Hacer Ebru Açıkgöz & Emre Sarandöl. (2020) Evaluation of percentage recovery together with modified reference range in hyperprolactinemia. Turkish Journal of Biochemistry 45:1, pages 37-43.
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Robert Krysiak, Karolina Kowalcze & Bogusław Okopień. (2019) Macroprolactinaemia modulates cardiometabolic effects of fenofibrate in men with atherogenic dyslipidaemia: A pilot study. Journal of Clinical Pharmacy and Therapeutics 45:1, pages 115-121.
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Raad A. Haddad, Donald Giacherio & Ariel L. Barkan. (2019) Interpretation of common endocrine laboratory tests: technical pitfalls, their mechanisms and practical considerations. Clinical Diabetes and Endocrinology 5:1.
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Nadine Binart, Jacques Young & Philippe Chanson. 2019. Prolactin Disorders. Prolactin Disorders 55 78 .
Lucio Vilar, Julio Abucham, José Luciano Albuquerque, Luiz Antônio Araujo, Monalisa F. Azevedo, Cesar Luiz Boguszewski, Luiz Augusto Casulari, Malebranche B. C. CunhaNetoNeto, Mauro A. Czepielewski, Felipe H. G. Duarte, Manuel dos S. Faria, Monica R. Gadelha, Heraldo M. Garmes, Andrea Glezer, Maria Helane Gurgel, Raquel S. Jallad, Manoel Martins, Paulo A. C. Miranda, Renan M. Montenegro, Nina R. C. Musolino, Luciana A. Naves, Antônio Ribeiro-OliveiraJúniorJúnior, Cíntia M. S. Silva, Camila Viecceli & Marcello D. Bronstein. (2018) Controversial issues in the management of hyperprolactinemia and prolactinomas – An overview by the Neuroendocrinology Department of the Brazilian Society of Endocrinology and Metabolism. Archives of Endocrinology and Metabolism 62:2, pages 236-263.
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Sema Ciftci Dogansen, Gulsah Yenidunya Yalin & Sema Yarman. (2018) Assessment of macroprolactinemia inpatients with prolactinoma. Turkish Journal of Biochemistry 43:1, pages 71-75.
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Kohzo Aisaka, Fujiko Tsuchiya, Masami Sueta, Kana Itabashi, Sayaka Nose, Akiko Hasegawa, Seiichiro Obata, Haruko Hiraike & Tetsuhiko Yokoyama. (2018) Impact of macroprolactin on galactorrhea and the rate of patients possibly affected by macroprolactin. Endocrine Journal 65:2, pages 203-211.
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Miro Kasum, Slavko Orešković, Ermin Čehić, Martina Šunj, Albert Lila & Emina Ejubović. (2017) Laboratory and clinical significance of macroprolactinemia in women with hyperprolactinemia. Taiwanese Journal of Obstetrics and Gynecology 56:6, pages 719-724.
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Anthony Emeka Madu. (2016) Management of Hyperprolactinaemia in Gynaecological Practice in Blackpool, United Kingdom, a Study of Earlier Experience, with a Review of Relevant Literature. Obstetrics & Gynecology International Journal 4:4.
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Robert Krysiak, Beata Kowalska, Witold Szkróbka & Bogusław Okopień. (2016) A neutral effect of testosterone therapy on macroprolactin content in men with macroprolactinemia and late-onset hypogonadism. Pharmacological Reports 68:1, pages 139-143.
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SusanbL. Samson, Amir H. Hamrahian & Shereen Ezzat. (2015) American Association of Clinical Endocrinologists, American College of Endocrinology Disease State Clinical Review: Clinical Relevance of Macroprolactin in the Absence or Presence of True Hyperprolactinemia. Endocrine Practice 21:12, pages 1427-1435.
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Michael N. Fahie-Wilson & Thomas P. Smith. (2015) Identification of IgG-K type macroprolactin found in the serum of an 8-year-old girl. Clinica Chimica Acta 441, pages 10.
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M. Kasum, D. Pavičić-Baldani, P. Stanić, S. Orešković, J-M. Šarić, J. Blajić & J. Juras. (2014) Importance of macroprolactinemia in hyperprolactinemia. European Journal of Obstetrics & Gynecology and Reproductive Biology 183, pages 28-32.
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Sollip Kim & Young-Min Park. (2013) Serum Prolactin and Macroprolactin Levels among Outpatients with Major Depressive Disorder Following the Administration of Selective Serotonin-Reuptake Inhibitors: A Cross-Sectional Pilot Study. PLoS ONE 8:12, pages e82749.
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Krithika Thirunavakkarasu, Pinaki Dutta, Subbiah Sridhar, Lakhbir Dhaliwal, G. R. V. Prashad, Shalini Gainder, Naresh Sachdeva & Anil Bhansali. (2013) Macroprolactinemia in hyperprolactinemic infertile women. Endocrine 44:3, pages 750-755.
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Macarena Alpañés, Raúl Sanchón, Mª Ángeles Martínez-García, Elena Martínez-Bermejo & Héctor F. Escobar-Morreale. (2013) Prevalence of hyperprolactinaemia in female premenopausal blood donors. Clinical Endocrinology 79:4, pages 545-549.
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Takashi Adachi, Naoki Hattori, Takashi Ishihara, Hirokazu Iida, Takanori Saito, Shigeo Miyashima & Akira Shimatsu. (2013) Possible involvement of matrix metalloproteinase-3 in the pathogenesis of macroprolactinaemia in some patients with rheumatoid arthritis. European Journal of Endocrinology 169:2, pages 203-209.
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Krzysztof C Lewandowski, Danuta Gąsior-Perczak, Aldona Kowalska & Andrzej Lewiński. (2012) Prevalence of macroprolactinaemia in regularly menstruating women with non-toxic goitre or autoimmune thyroid disease. Thyroid Research 5:1.
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Naoki Hattori, Takashi Adachi, Takashi Ishihara & Akira Shimatsu. (2012) The natural history of macroprolactinaemia. European Journal of Endocrinology 166:4, pages 625-629.
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Serhat Isik, Dilek Berker, Yasemin Ates Tutuncu, Ufuk Ozuguz, Ferhat Gokay, Gonul Erden, Hatice Nursun Ozcan, Ferit Kerim Kucukler, Yusuf Aydin & Serdar Guler. (2011) Clinical and radiological findings in macroprolactinemia. Endocrine 41:2, pages 327-333.
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Chih-Chin Lu & Ching-Jung Hsieh. (2012) The importance of measuring macroprolactin in the differential diagnosis of hyperprolactinemic patients. The Kaohsiung Journal of Medical Sciences 28:2, pages 94-99.
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Eva Landberg, Ulf Dahlström & Urban Alehagen. (2010) Serum prolactin and macroprolactin in heart failure: no relation to established laboratory or clinical parameters. Annals of Clinical Biochemistry: International Journal of Laboratory Medicine 48:1, pages 51-56.
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Naoki Hattori, Takashi Ishihara, Yasuhiko Saiki & Akira Shimatsu. (2010) Macroprolactinaemia in patients with hyperprolactinaemia: composition of macroprolactin and stability during long‐term follow‐up. Clinical Endocrinology 73:6, pages 792-797.
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I. R. Wallace, N. Satti, C. H. Courtney, H. Leslie, P. M. Bell, S. J. Hunter, D. R. McCance, B. Sheridan & A. B. Atkinson. (2010) Ten-Year Clinical Follow-Up of a Cohort of 51 Patients with Macroprolactinemia Establishes It as a Benign Variant. The Journal of Clinical Endocrinology & Metabolism 95:7, pages 3268-3271.
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G A Mel'nichenko, N P Goncharov, L K Dzeranova, A D Dobracheva & I I Barmina. (2010) Clinical and laboratory aspects of investigations into prolactin isoforms by PEG precipitation and ultrafiltration techniques. Problems of Endocrinology 56:1, pages 19-25.
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Naoki Hattori, Takashi Ishihara & Yasuhiko Saiki. (2009) Macroprolactinaemia: prevalence and aetiologies in a large group of hospital workers. Clinical Endocrinology 71:5, pages 702-708.
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T. Joseph McKenna. (2009) Should macroprolactin be measured in all hyperprolactinaemic sera?. Clinical Endocrinology 71:4, pages 466-469.
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Patrícia Coelho de Soárez, Silvia Corral de Arêa Leão Souza, José Gilberto Henriques Vieira & Marcos Bosi Ferraz. (2009) The Effect of Identifying Macroprolactinemia on Health-Care Utilization and Costs in Patients with Elevated Serum Prolactin Levels. Value in Health 12:6, pages 930-934.
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Lucille Kavanagh-Wright, Thomas P. Smith, James Gibney & T. Joseph McKenna. (2009) Characterization of macroprolactin and assessment of markers of autoimmunity in macroprolactinaemic patients. Clinical Endocrinology 70:4, pages 599-605.
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Andrew C. Don-Wauchope, Mariza Hoffmann, Mia le Riche & Brynne H. Ascott-Evans. (2009) Review of the prevalence of macroprolactinaemia in a South African hospital. Clinical Chemistry and Laboratory Medicine 47:7.
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T Joseph McKenna & Thomas Smith. (2008) Hyperprolactinemia Due to Macroprolactin. The Endocrinologist 18:5, pages 249-254.
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M. Jane Ellis, Maxine R. Reed & John H. Livesey. (2007) Cross-reactivities of macroprolactin and big-prolactin in three commercial immunoassays for prolactin: A chromatographic analysis. Clinical Biochemistry 40:16-17, pages 1285-1290.
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Naoki Hattori, Yasuhisa Nakayama, Kaori Kitagawa, Tiesong Li & Chiyoko Inagaki. (2007) Development of Anti-PRL (Prolactin) Autoantibodies by Homologous PRL in Rats: A Model for Macroprolactinemia. Endocrinology 148:5, pages 2465-2470.
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M. Jane Ellis, John H. Livesey & Steven G. Soule. (2006) Macroprolactin, big-prolactin and potential effects on the misdiagnosis of hyperprolactinemia using the Beckman Coulter Access Prolactin assay. Clinical Biochemistry 39:10, pages 1028-1034.
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Paula Álvarez-Vázquez, Digna Rodríguez Pérez, Elías Álvarez García, Concha Páramo Fernández, Elena Hervás Abad & María Amalia Andrade Olivié. (2006) Significación clínica de la macroprolactina. Endocrinología y Nutrición 53:6, pages 374-378.
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Abel Alfonso, Kimberly I. Rieniets & Robert A. Vigersky. (2006) Incidence and Clinical Significance of Elevated Macroprolactin Levels in Patients with Hyperprolactinemia. Endocrine Practice 12:3, pages 275-280.
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H. Sadideen & R. Swaminathan. (2006) Macroprolactin: what is it and what is its importance?. International Journal of Clinical Practice 60:4, pages 457-461.
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Frank Nawroth. (2005) Hyperprolactinaemia and the regular menstrual cycle in asymptomatic women: should it be treated during therapy for infertility?. Reproductive BioMedicine Online 11:5, pages 581-588.
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L. P. Pinto, F. W. F. Hanna, L. M. Evans, J. S. Davies, R. John & M. F. Scanlon. (2003) The TSH response to domperidone reflects the biological activity of prolactin in macroprolactinaemia and hyperprolactinaemia. Clinical Endocrinology 59:5, pages 580-584.
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