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Original Article

A mathematical/physiological model of parathyroid hormone secretion in response to blood-ionized calcium lowering in vivo

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Pages 381-394 | Received 24 Jun 1996, Accepted 05 Mar 1997, Published online: 08 Jul 2009

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Derya Aslan, Mille Dahl Andersen, Lene Bjerring Gede, Tine Kellemann de Franca, Sara Rubek Jørgensen, Peter Schwarz & Niklas Rye Jørgensen. (2012) Mechanisms for the bone anabolic effect of parathyroid hormone treatment in humans. Scandinavian Journal of Clinical and Laboratory Investigation 72:1, pages 14-22.
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Articles from other publishers (12)

Gudrun Schappacher-Tilp, Peter Kotanko & Markus Pirklbauer. (2022) Mathematical Models of Parathyroid Gland Biology: Complexity and Clinical Use. Frontiers in Nephrology 2.
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Alexandr M. Miromanov & Kirill A. Gusev. (2021) Osteogenesis Hormonal Regulation: Review. Traumatology and Orthopedics of Russia 27:4, pages 120-130.
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Gudrun Schappacher‐Tilp, Alhaji Cherif, Doris H. Fuertinger, David Bushinsky & Peter Kotanko. (2019) A mathematical model of parathyroid gland biology. Physiological Reports 7:7, pages e14045.
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Inthira Chaiya & Chontita Rattanakul. (2017) Effects of prolactin on bone remodeling process with parathyroid hormone supplement: an impulsive mathematical model. Advances in Difference Equations 2017:1.
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P Chen, P Olsson Gisleskog, JJ Perez-Ruixo, J Xiao, J Wilkins, A Narayanan, JP Gibbs & M Melhem. (2016) Population Pharmacokinetics and Pharmacodynamics of the Calcimimetic Etelcalcetide in Chronic Kidney Disease and Secondary Hyperparathyroidism Receiving Hemodialysis. CPT: Pharmacometrics & Systems Pharmacology 5:9, pages 484-494.
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Jun Shen, Jim Xiao, Karen Pickthorn, Saling Huang, Gregory Bell, Andrew Vick & Ping Chen. (2014) A pharmacokinetic/pharmacodynamic model for AMG 416, a novel calcimimetic peptide, following a single intravenous dose in healthy subjects. The Journal of Clinical Pharmacology 54:10, pages 1125-1133.
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William A. Pruett & Robert L. Hester. (2014) Parathyroid hormone secretion by multiple distinct cell populations, a time dynamic mathematical model. Physiological Reports 2:2, pages e00231.
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William A. Pruett, Robert L. Hester & Thomas G. Coleman. (2012) The apparent hysteresis in hormone-agonist relationships. Journal of Theoretical Biology 296, pages 1-5.
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Anson K. Abraham, Tristan S. Maurer, Amit S. Kalgutkar, Xiang Gao, Mei Li, David R. Healy, Donna N. Petersen, David A. Griffith & Donald E. Mager. (2011) Pharmacodynamic Model of Parathyroid Hormone Modulation by a Negative Allosteric Modulator of the Calcium-Sensing Receptor. The AAPS Journal 13:2, pages 265-273.
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Rajiv P. Shrestha, Christopher V. Hollot, Stuart R. Chipkin, Claus P. Schmitt & Yossi Chait. (2010) A mathematical model of parathyroid hormone response to acute changes in plasma ionized calcium concentration in humans. Mathematical Biosciences 226:1, pages 46-57.
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Anson K. Abraham, Donald E. Mager, Xiang Gao, Mei Li, David R. Healy & Tristan S. Maurer. (2009) Mechanism-Based Pharmacokinetic/Pharmacodynamic Model of Parathyroid Hormone-Calcium Homeostasis in Rats and Humans. Journal of Pharmacology and Experimental Therapeutics 330:1, pages 169-178.
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Chontita Rattanakul, Yongwimon Lenbury, Nateetip Krishnamara & David J. Wollkind. (2003) Modeling of bone formation and resorption mediated by parathyroid hormone: response to estrogen/PTH therapy. Biosystems 70:1, pages 55-72.
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