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Scandinavian Journal of Gastroenterology Volume 47, 2012 - Issue 3
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Review Article

Predictive biomarkers in colorectal cancer: usage, validation, and design in clinical trials

Qian ShiDepartment of Health Science Research, Mayo Clinic, Rochester, MN, USA
,
Sumithra J. MandrekarDepartment of Health Science Research, Mayo Clinic, Rochester, MN, USA
&
Daniel J. SargentDepartment of Health Science Research, Mayo Clinic, Rochester, MN, USA
Pages 356-362 | Accepted 11 Nov 2011, Published online: 19 Dec 2011

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Read on this site (3)

Fang Xia, Stephen L. George, Jing Ning, Liang Li & Xuelin Huang. (2021) A signature enrichment design with Bayesian adaptive randomization. Journal of Applied Statistics 48:6, pages 1091-1110.
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Theresa L Whiteside. (2015) The potential of tumor-derived exosomes for noninvasive cancer monitoring. Expert Review of Molecular Diagnostics 15:10, pages 1293-1310.
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Hans J. Nielsen & Nils Brünner. (2012) EDITORIAL. Scandinavian Journal of Gastroenterology 47:3, pages 256-257.
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Articles from other publishers (10)

Miranta Antoniou, Ruwanthi Kolamunnage-Dona & Andrea Jorgensen. (2017) Biomarker-Guided Non-Adaptive Trial Designs in Phase II and Phase III: A Methodological Review. Journal of Personalized Medicine 7:1, pages 1.
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Dung-Tsa Chen, Po-Yu Huang, Hui-Yi Lin, Eric B. Haura, Scott J. Antonia, W. Douglas Cress & Jhanelle E. Gray. (2016) Strategies for power calculations in predictive biomarker studies in survival data. Oncotarget 7:49, pages 80373-80381.
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Rui-Ting Liu, Guo-Rong Wang, Chang Liu, Jian Qiu, Li-Kun Yan, Xiao-Jun Li & Xiao-Qiang Wang. (2016) RNAi-mediated downregulation of DNA binding protein A inhibits tumorigenesis in colorectal cancer. International Journal of Molecular Medicine 38:3, pages 703-712.
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Miranta Antoniou, Andrea L Jorgensen & Ruwanthi Kolamunnage-Dona. (2016) Biomarker-Guided Adaptive Trial Designs in Phase II and Phase III: A Methodological Review. PLOS ONE 11:2, pages e0149803.
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Tilman Laubert, Sandra Freitag-Wolf, Michael Linnebacher, Alexandra König, Brigitte Vollmar & Jens K. Habermann. (2015) Stage-specific frequency and prognostic significance of aneuploidy in patients with sporadic colorectal cancer—a meta-analysis and current overview. International Journal of Colorectal Disease 30:8, pages 1015-1028.
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Shaoju Jin, Yishuang Mu, Xiaodong Wang, Zhenru Liu, Lihong Wan, Yao Xiong, Yuanyuan Zhang, Liming Zhou & Li Li. (2014) Overexpressed RACK1 is positively correlated with malignant degree of human colorectal carcinoma. Molecular Biology Reports 41:5, pages 3393-3399.
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Sumithra J. Mandrekar, Ming-Wen An & Daniel J. Sargent. (2013) A review of phase II trial designs for initial marker validation. Contemporary Clinical Trials 36:2, pages 597-604.
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Parvin Tajik, Aleiko H. Zwinderman, Ben W. Mol & Patrick M. Bossuyt. (2013) Trial Designs for Personalizing Cancer Care: A Systematic Review and Classification. Clinical Cancer Research 19:17, pages 4578-4588.
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Michael Tachezy, Hilke Zander, Florian Gebauer, Andreas Marx, Jussuf T. Kaifi, Jakob R. Izbicki & Maximilian Bockhorn. (2012) Activated leukocyte cell adhesion molecule (CD166)—Its prognostic power for colorectal cancer patients. Journal of Surgical Research 177:1, pages e15-e20.
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Qian Shi & Daniel J Sargent. (2012) From isolated hypotheses to connected practical studies: statisticians’ role in a seamless targeted therapy development. Future Medicinal Chemistry 4:8, pages 943-945.
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