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Gastrointestinal Cancer

Optimal cutoff value of the serum pepsinogen level for prediction of gastric cancer incidence: the Hisayama Study

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Pages 669-675 | Received 27 Oct 2011, Accepted 01 Jan 2012, Published online: 20 Mar 2012

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Takahiro Shinozuka, Mitsuro Kanda & Yasuhiro Kodera. (2023) Site-specific protein biomarkers in gastric cancer: a comprehensive review of novel biomarkers and clinical applications. Expert Review of Molecular Diagnostics 23:8, pages 701-712.
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Haejin In, Srawani Sarkar, Jessica Ward, Patricia Friedmann, Michael Parides, Julie Yang & Meira Epplein. (2022) Serum Pepsinogen as a Biomarker for Gastric Cancer in the United States: A Nested Case–Control Study Using the PLCO Cancer Screening Trial Data. Cancer Epidemiology, Biomarkers & Prevention 31:7, pages 1426-1432.
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Xiao-Lei Han, Chang-Lin Yi, Jin-Dan Ma, Yanhong He, La-Mei Wu, Yun-Feng Wang, Hui-Jian Yang, Dong-Yu Liang & Jin-Fang Shi. (2022) Clinical Value of Pepsinogen in the Screening, Prevention, and Diagnosis of Gastric Cancer. Laboratory Medicine 53:1, pages 71-77.
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Zhen-Yu Wang & Jian-Guo Zhang. (2020) The Role of Helicobacter pylori and Serum Pepsinogen Levels in Metachronous Gastric Cancer After Endoscopic Gastrectomy. Surgical Laparoscopy, Endoscopy & Percutaneous Techniques 30:5, pages 447-450.
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Tsung-Hsien Chiang, Sherry Yueh-Hsia Chiu, Sam Li-Sheng Chen, Amy Ming-Fang Yen, Jean Ching-Yuan Fann, Cheng-Ying Liu, Chu-Kuang Chou, Han-Mo Chiu, Chia-Tung Shun, Ming-Shiang Wu, Jaw-Town Lin, Yi-Chia Lee, Tony Hsiu-Hsi Chen & Ming-Wei Lin. (2019) Serum Pepsinogen as a Predictor for Gastric Cancer Death. Journal of Clinical Gastroenterology 53:5, pages e186-e193.
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Ling Liu, Junjie Lang, Yuelong Jin, Yan Chen, Weiwei Chang, Yingshui Yao & Jiegen Yu. (2019) The Value of Pepsinogen in GC Screening: A Systematic Review and Meta-Analysis. Gastroenterology Research and Practice 2019, pages 1-11.
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Yuling Tong, Yulian Wu, Zhenya Song, Yingying Yu & Xinyan Yu. (2017) The potential value of serum pepsinogen for the diagnosis of atrophic gastritis among the health check-up populations in China: a diagnostic clinical research. BMC Gastroenterology 17:1.
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Huakang Tu, Liping Sun, Xiao Dong, Yuehua Gong, Qian Xu, Jingjing Jing, Roberd M Bostick, Xifeng Wu & Yuan Yuan. (2017) A Serological Biopsy Using Five Stomach-Specific Circulating Biomarkers for Gastric Cancer Risk Assessment: A Multi-Phase Study. American Journal of Gastroenterology 112:5, pages 704-715.
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Su Youn Nam, Seong Woo Jeon, Hyun Seok Lee, Yong Hwan Kwon, Haeyoon Park & Jin Woo Choi. (2017) Long-term follow-up of pepsinogen I/II ratio after eradication of Helicobacter pylori in patients who underwent endoscopic mucosal resection for gastric cancer. Digestive and Liver Disease 49:5, pages 500-506.
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Jennifer M Yeh, Chin Hur, Zachary Ward, Deborah Schrag & Sue J Goldie. (2016) Gastric adenocarcinoma screening and prevention in the era of new biomarker and endoscopic technologies: a cost-effectiveness analysis. Gut 65:4, pages 563-574.
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Fumie Ikeda, Kentaro Shikata, Jun Hata, Masayo Fukuhara, Yoichiro Hirakawa, Tomoyuki Ohara, Naoko Mukai, Masaharu Nagata, Daigo Yoshida, Koji Yonemoto, Motohiro Esaki, Takanari Kitazono, Yutaka Kiyohara & Toshiharu Ninomiya. (2016) Combination of <i>Helicobacter pylori</i> Antibody and Serum Pepsinogen as a Good Predictive Tool of Gastric Cancer Incidence: 20-Year Prospective Data From the Hisayama Study. Journal of Epidemiology 26:12, pages 629-636.
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Carlo‐Federico Zambon, Daniela Basso, Michela Pelloso, Alberto Tessari & Mario Plebani. 2015. Human Emerging and Re‐emerging Infections. Human Emerging and Re‐emerging Infections 607 634 .
Ya-kai Huang, Jian-chun Yu, Wei-ming Kang, Zhi-qiang Ma, Xin Ye, Shu-bo Tian & Chao Yan. (2015) Significance of Serum Pepsinogens as a Biomarker for Gastric Cancer and Atrophic Gastritis Screening: A Systematic Review and Meta-Analysis. PLOS ONE 10:11, pages e0142080.
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Yao-Kuang Wang. (2015) Diagnosis of Helicobacter pylori infection: Current options and developments . World Journal of Gastroenterology 21:40, pages 11221.
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Violet Kayamba, Mumba Chomba & Paul Kelly. (2014) Short term micronutrient-antioxidant supplementation has no impact on a serological marker of gastric atrophy in Zambian adults: retrospective analysis of a randomised controlled trial. BMC Gastroenterology 14:1.
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Teresa Martínez, María Mercedes Bravo, Diana Leandra Núñez, Gustavo A. Hernández & Margarita Camorlinga. (2014) Niveles séricos de pepsinógeno y su capacidad diagnóstica de atrofia gástrica en diferentes poblaciones colombianas. Revista Colombiana de Cancerología 18:4, pages 166-178.
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Fatemeh Nejadi-Kelarijani, Gholamreza Roshandel, Shahryar Semnani, Ali Ahmadi, Behzad Faghani, Sima Besharat, Atefeh Akhavan-Tabib & Taghi Amiriani. (2014) Diagnostic Values of Serum Levels of Pepsinogens and Gastrin-17 for Screening Gastritis and Gastric Cancer in a High Risk Area in Northern Iran. Asian Pacific Journal of Cancer Prevention 15:17, pages 7433-7436.
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Cheryl E. Ainslie-Waldman, Woon-Puay Koh, Aizhen Jin, Khay Guan Yeoh, Feng Zhu, Renwei Wang, Jian-Min Yuan & Lesley M. Butler. (2014) Coffee Intake and Gastric Cancer Risk: The Singapore Chinese Health Study. Cancer Epidemiology, Biomarkers & Prevention 23:4, pages 638-647.
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Xavier Calvet, María-José Ramírez Lázaro, Philippe Lehours & Francis Mégraud. (2013) Diagnosis and Epidemiology of Helicobacter pylori Infection . Helicobacter 18, pages 5-11.
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Peter Malfertheiner, Michael Selgrad & Jan Bornschein. (2012) Helicobacter pylori. Current Opinion in Gastroenterology 28:6, pages 608-614.
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Michael Selgrad, Jan Bornschein, Theodore Rokkas & Peter Malfertheiner. (2012) Helicobacter pylori: Gastric Cancer and Extragastric Intestinal Malignancies. Helicobacter 17, pages 30-35.
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