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Scandinavian Journal of Gastroenterology Volume 48, 2013 - Issue 12
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Oncology

Underpinning the repurposing of anthracyclines towards colorectal cancer: assessment of topoisomerase II alpha gene copy number alterations in colorectal cancer

Sune Boris NygårdDepartment of Veterinary Disease Biology, Faculty of Health and Medical Sciences, University of Copenhagen, Section for Molecular Disease Biology, Copenhagen Ø, DenmarkCorrespondence[email protected]
,
Ib Jarle ChristensenFinsen Laboratory, Rigshospitalet and Biotech Research and Innovation Centre (BRIC), University of Copenhagen, Copenhagen Biocenter, Copenhagen N, Denmark
,
David Hersi SmithDepartment of Veterinary Disease Biology, Faculty of Health and Medical Sciences, University of Copenhagen, Section for Molecular Disease Biology, Copenhagen Ø, Denmark;R&D, Dako A/S, Glostrup, Denmark
,
Signe Lykke NielsenDepartment of Veterinary Disease Biology, Faculty of Health and Medical Sciences, University of Copenhagen, Section for Molecular Disease Biology, Copenhagen Ø, Denmark
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Niels Frank JensenDepartment of Veterinary Disease Biology, Faculty of Health and Medical Sciences, University of Copenhagen, Section for Molecular Disease Biology, Copenhagen Ø, Denmark
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Hans Jørgen NielsenDepartment of Surgical Gastroenterology 360, Hvidovre Hospital, Hvidovre, Denmark;Institute of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen N, Denmark
,
Ben VainerDepartment of Pathology, Rigshospitalet, Copenhagen Ø, Denmark
&
Nils BrünnerDepartment of Veterinary Disease Biology, Faculty of Health and Medical Sciences, University of Copenhagen, Section for Molecular Disease Biology, Copenhagen Ø, Denmark
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Pages 1436-1443 | Received 27 Aug 2013, Accepted 18 Sep 2013, Published online: 21 Oct 2013

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Line S. Tarpgaard, Camilla Qvortrup, Signe L. Nielsen, Jan Stenvang, Sönke Detlefsen, Nils Brünner & Per Pfeiffer. (2021) New use for old drugs: Epirubicin in colorectal cancer. Acta Oncologica 60:7, pages 954-956.
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Articles from other publishers (7)

Robson Francisco Carvalho, Luisa Matos do Canto, Sarah Santiloni Cury, Torben Frøstrup Hansen, Lars Henrik Jensen & Silvia Regina Rogatto. (2021) Drug Repositioning Based on the Reversal of Gene Expression Signatures Identifies TOP2A as a Therapeutic Target for Rectal Cancer. Cancers 13:21, pages 5492.
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Shanshan Chen, Yi Fang, Lingyu Sun, Ruonan He, Beihui He & Shuo Zhang. (2021) Long Non-Coding RNA: A Potential Strategy for the Diagnosis and Treatment of Colorectal Cancer. Frontiers in Oncology 11.
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Zainab Al-Taie, Danlu Liu, Jonathan B Mitchem, Christos Papageorgiou, Jussuf T. Kaifi, Wesley C. Warren & Chi-Ren Shyu. (2021) Explainable artificial intelligence in high-throughput drug repositioning for subgroup stratifications with interventionable potential. Journal of Biomedical Informatics 118, pages 103792.
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Jessica M. Silva-Fisher, Ha X. Dang, Nicole M. White, Matthew S. Strand, Bradley A. Krasnick, Emily B. Rozycki, Gejae G. L. Jeffers, Julie G. Grossman, Maureen K. Highkin, Cynthia Tang, Christopher R. Cabanski, Abdallah Eteleeb, Jacqueline Mudd, S. Peter Goedegebuure, Jingqin Luo, Elaine R. Mardis, Richard K. Wilson, Timothy J. Ley, Albert C. Lockhart, Ryan C. Fields & Christopher A. Maher. (2020) Long non-coding RNA RAMS11 promotes metastatic colorectal cancer progression. Nature Communications 11:1.
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Line S. Tarpgaard, Camilla Qvortrup, Sune B. Nygård, Signe L. Nielsen, Diana R. Andersen, Niels Frank Jensen, Jan Stenvang, Sönke Detlefsen, Nils Brünner & Per Pfeiffer. (2016) A phase II study of Epirubicin in oxaliplatin-resistant patients with metastatic colorectal cancer and TOP2A gene amplification. BMC Cancer 16:1.
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Mette Ø. Pedersen, Tim S. Poulsen, Anne O. Gang, Helle Knudsen, Anne F. Lauritzen, Michael Pedersen, Signe L. Nielsen, Peter Brown, Estrid Høgdall & Peter Nørgaard. (2015) Lack of topoisomerase copy number changes in patients with de novo and relapsed diffuse large B-cell lymphoma. Experimental Hematology 43:7, pages 534-536.
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Ida Marie Heeholm Sønderstrup, Sune Boris Nygård, Tim Svenstrup Poulsen, Dorte Linnemann, Jan Stenvang, Hans Jørgen Nielsen, Jiri Bartek, Nils Brünner, Peter Nørgaard & Lene Riis. (2015) Topoisomerase-1 and -2A gene copy numbers are elevated in mismatch repair-proficient colorectal cancers. Molecular Oncology 9:6, pages 1207-1217.
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