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Scandinavian Journal of Gastroenterology Volume 51, 2016 - Issue 5
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Original Article

A prospective study on the causes of notably raised alanine aminotransferase (ALT)

Helgi Kristinn BjörnssonFaculty of Medicine, University of Iceland, Reykjavík, Iceland;
,
Sigurdur OlafssonMedical Faculty, Division of Gastroenterology and Hepatology, Department of the Internal Medicine, The National University Hospital of Iceland, Reykjavík, Iceland
,
Ottar M. BergmannMedical Faculty, Division of Gastroenterology and Hepatology, Department of the Internal Medicine, The National University Hospital of Iceland, Reykjavík, Iceland
&
Einar S. BjörnssonFaculty of Medicine, University of Iceland, Reykjavík, Iceland; ;Medical Faculty, Division of Gastroenterology and Hepatology, Department of the Internal Medicine, The National University Hospital of Iceland, Reykjavík, IcelandCorrespondence[email protected]
Pages 594-600 | Received 18 Oct 2015, Accepted 15 Nov 2015, Published online: 14 Dec 2015

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Helgi Kristinn Björnsson & Einar Stefan Björnsson. (2023) Review of human risk factors for idiosyncratic drug-induced liver injury: latest advances and future goals. Expert Opinion on Drug Metabolism & Toxicology 0:0, pages 1-9.
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Sigrún Jonsdottir, Margrét B. Arnardottir, Jóhannes A. Andresson, Helgi K. Bjornsson, Sigrun H. Lund & Einar S. Bjornsson. (2022) Prevalence, clinical characteristics and outcomes of hypoxic hepatitis in critically ill patients. Scandinavian Journal of Gastroenterology 57:3, pages 311-318.
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Helgi K. Björnsson & Einar S. Björnsson. (2019) A significant proportion of patients with choledocholithiasis have markedly elevated alanine aminotransferase. Scandinavian Journal of Gastroenterology 54:9, pages 1155-1159.
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Hilmar Leonardsson, Jóhann Páll Hreinsson, Arthur Löve & Einar S. Björnsson. (2017) Hepatitis due to Epstein–Barr virus and cytomegalovirus: clinical features and outcomes. Scandinavian Journal of Gastroenterology 52:8, pages 893-897.
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Articles from other publishers (23)

Rei Hirano, Tatsuo Kanda, Masayuki Honda, Shuhei Arima, Mai Totsuka, Ryota Masuzaki, Shini Kanezawa, Reina Sasaki-Tanaka, Naoki Matsumoto, Hiroaki Yamagami, Tomotaka Ishii, Masahiro Ogawa, Shuzo Nomura, Mariko Fujisawa, Kei Saito, Masaharu Takahashi, Hiroaki Okamoto & Hirofumi Kogure. (2023) Hepatitis E Virus Infection Caused Elevation of Alanine Aminotransferase Levels in a Patient with Chronic Hepatitis B and Choledocholithiasis. Reports 6:4, pages 55.
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Mouhand F. H. Mohamed, Khaled Elfert, Neha Wadhavkar, Daniel Marino, Kanhai Farrakhan, Azizullah Beran, Mohamed A. Abdallah, Abubaker Abdalla & Ronan Farrell. (2023) Choledocholithiasis Can Present with Marked Transaminases Elevation: Systematic Review and Meta-Analysis. Digestive Diseases and Sciences 68:8, pages 3428-3435.
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Robert J. Fontana, Iris Liou, Adrian Reuben, Ayako Suzuki, M. Isabel Fiel, William Lee & Victor Navarro. (2023) AASLD practice guidance on drug, herbal, and dietary supplement–induced liver injury. Hepatology 77:3, pages 1036-1065.
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晓月 谢. (2023) Etiology and Diagnosis and Treatment of Markedly Elevated Transaminases. Advances in Clinical Medicine 13:10, pages 16797-16806.
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Ji-Hee Han, Ji-Yoon Kwak, Sang-Soo Lee, Hyun-Gyu Kim, Hankyu Jeon & Ra-Ri Cha. (2022) Markedly Elevated Aspartate Aminotransferase from Non-Hepatic Causes. Journal of Clinical Medicine 12:1, pages 310.
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HK Björnsson & ES Björnsson. (2022) Drug-induced liver injury: Pathogenesis, epidemiology, clinical features, and practical management. European Journal of Internal Medicine 97, pages 26-31.
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Manasvi Gupta, Gaurav Manek, Kaitlyn Dombrowski & Rakhi Maiwall. (2021) Newer developments in viral hepatitis: Looking beyond hepatotropic viruses. World Journal of Meta-Analysis 9:6, pages 522-542.
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Temidayo Ogunmoyole, Iretiogo Dada & Oluwatosin Adebukola Adebamigbe. (2021) Ameliorative potentials of Persea americana leaf extract on toxicants - induced oxidative assault in multiple organs of wistar albino rat. Clinical Phytoscience 7:1.
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Marina Curra, Amanda F. Gabriel, Maria Beatriz C. Ferreira, Marco Antonio T. Martins, André T. Brunetto, Lauro J. Gregianin & Manoela Domingues Martins. (2021) Incidence and risk factors for oral mucositis in pediatric patients receiving chemotherapy. Supportive Care in Cancer 29:11, pages 6243-6251.
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Maomao Liu, Wen Tan, Wen Yuan, Tengke Wang, Xuran Lu & Nan Liu. (2021) Development and Validation of a Diagnostic Model to Predict the Risk of Ischemic Liver Injury After Stanford A Aortic Dissection Surgery. Frontiers in Cardiovascular Medicine 8.
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Einar S. Björnsson. (2021) Clinical management of patients with drug‐induced liver injury (DILI). United European Gastroenterology Journal 9:7, pages 781-786.
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Chalermrat Bunchorntavakul & K. Rajender Reddy. (2020) Epstein-Barr Virus and Cytomegalovirus Infections of the Liver. Gastroenterology Clinics of North America 49:2, pages 331-346.
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Danny Con, Andrew Buckle, Amanda J Nicoll & John S Lubel. (2020) Epidemiology and outcomes of marked elevations of alanine aminotransferase >1000 IU/L in an Australian cohort. JGH Open 4:2, pages 106-112.
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Kjartan B. Valgeirsson, Jóhann P. Hreinsson & Einar S. Björnsson. (2019) Increased incidence of autoimmune hepatitis is associated with wider use of biological drugs. Liver International 39:12, pages 2341-2349.
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Raúl J. Andrade, Guruprasad P. Aithal, Einar S. Björnsson, Neil Kaplowitz, Gerd A. Kullak-Ublick, Dominique Larrey & Tom H. Karlsen. (2019) EASL Clinical Practice Guidelines: Drug-induced liver injury. Journal of Hepatology 70:6, pages 1222-1261.
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Anthony C. Breu, Vilas R. Patwardhan, Jennifer Nayor, Jalpan N. Ringwala, Zachary G. Devore, Rahul B. Ganatra, Kelly E. Hathorn, Laura Horton, Sentia Iriana & Elliot B. Tapper. (2019) A Multicenter Study Into Causes of Severe Acute Liver Injury. Clinical Gastroenterology and Hepatology 17:6, pages 1201-1203.
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Alejandra Cano-Paniagua, Pedro Amariles, Nancy Angulo & Margarita Restrepo-Garay. (2019) Epidemiology of drug-induced liver injury in a University Hospital from Colombia: Updated RUCAM being used for prospective causality assessment. Annals of Hepatology 18:3, pages 501-507.
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Hemda Schmilovitz-Weiss, Rachel Gingold-Belfer, Alon Grossman, Nidal Issa, Doron Boltin, Yichayaou Beloosesky, Nira Morag Koren, Joseph Meyerovitch & Avraham Weiss. (2019) Lowering the upper limit of serum alanine aminotransferase levels may reveal significant liver disease in the elderly. PLOS ONE 14:4, pages e0212737.
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Stefanie Quickert, Philipp A. Reuken, Michael Rose, Katharina Boden & Tony Bruns. (2019) Acute Hepatitis E is an Underreported Cause of Severe Acute Liver Injury. Clinical Gastroenterology and Hepatology 17:5, pages 1004-1006.
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Mitchell R. McGill & Hartmut Jaeschke. 2019. Drug-induced Liver Injury. Drug-induced Liver Injury 221 239 .
Xiao Li, Tai-Cheng Zhou, Chang-Hui Wu, Li-Lin Tao, Rui Bi, Li-Jun Chen, De-Yao Deng, Chang Liu, Newton O. Otecko, Yang Tang, Xin Lai, Liang Zhang & Jia Wei. (2018) Correlations between mitochondrial DNA haplogroup D5 and chronic hepatitis B virus infection in Yunnan, China. Scientific Reports 8:1.
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Mohammed M. Aboelsoud, Amen I. Javaid, Mazen O. Al-Qadi & James H. Lewis. (2017) Hypoxic hepatitis — its biochemical profile, causes and risk factors of mortality in critically-ill patients: A cohort study of 565 patients. Journal of Critical Care 41, pages 9-15.
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Einar Stefan Björnsson, Ottar Bergmann, Jon Gunnlaugur Jonasson, Gerdur Grondal, Björn Gudbjornsson & Sigurdur Olafsson. (2017) Drug-Induced Autoimmune Hepatitis: Response to Corticosteroids and Lack of Relapse After Cessation of Steroids. Clinical Gastroenterology and Hepatology 15:10, pages 1635-1636.
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