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Original Article

Elevated Fecal Levels of Endogenous Pancreatic Endopeptidases after Antibiotic Treatment

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Pages 525-529 | Received 21 Jan 1977, Accepted 15 Feb 1977, Published online: 23 Feb 2010

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M. Bohe. (1987) Pancreatic and Granulocytic Endoproteases in Faecal Extracts from Patients with Active Ulcerative Colitis. Scandinavian Journal of Gastroenterology 22:1, pages 59-64.
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Youxian Li, Eiichiro Watanabe, Yusuke Kawashima, Damian R. Plichta, Zhujun Wang, Makoto Ujike, Qi Yan Ang, Runrun Wu, Munehiro Furuichi, Kozue Takeshita, Koji Yoshida, Keita Nishiyama, Sean M. Kearney, Wataru Suda, Masahira Hattori, Satoshi Sasajima, Takahiro Matsunaga, Xiaoxi Zhang, Kazuto Watanabe, Jun Fujishiro, Jason M. Norman, Bernat Olle, Shutoku Matsuyama, Ho Namkoong, Yoshifumi Uwamino, Makoto Ishii, Koichi Fukunaga, Naoki Hasegawa, Osamu Ohara, Ramnik J. Xavier, Koji Atarashi & Kenya Honda. (2022) Identification of trypsin-degrading commensals in the large intestine. Nature 609:7927, pages 582-589.
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Hongsup Yoon, Monika Schaubeck, Ilias Lagkouvardos, Andreas Blesl, Stephanie Heinzlmeir, Hannes Hahne, Thomas Clavel, Suchita Panda, Christina Ludwig, Bernhard Kuster, Chaysavanh Manichanh, Patrizia Kump, Dirk Haller & Gabriele Hörmannsperger. (2018) Increased Pancreatic Protease Activity in Response to Antibiotics Impairs Gut Barrier and Triggers Colitis. Cellular and Molecular Gastroenterology and Hepatology 6:3, pages 370-388.e3.
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Kangkang Zhou, Mingshan Jiang, Xiaofa Qin & Xiuhong Wang. (2015) Role of bilirubin in digestive proteases inactivation in the lower intestine. Digestive and Liver Disease 47:5, pages 438-439.
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David Tooth, Klara Garsed, Gulzar Singh, Luca Marciani, Ching Lam, Imogen Fordham, Annie Fields, Rawinder Banwait, Melanie Lingaya, Robert Layfield, Maggie Hastings, Peter Whorwell & Robin Spiller. (2014) Characterisation of faecal protease activity in irritable bowel syndrome with diarrhoea: origin and effect of gut transit. Gut 63:5, pages 753-760.
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Osamu Ikehara, Hisayoshi Hayashi, Toshiharu Waguri, Izumi Kaji, Shin-ichiro Karaki, Atsukazu Kuwahara & Yuichi Suzuki. (2014) Luminal trypsin induces enteric nerve-mediated anion secretion in the mouse cecum. The Journal of Physiological Sciences 64:2, pages 119-128.
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Xiaofa Qin. (2014) May bacterial or pancreatic proteases play a critical role in inflammatory bowel disease?. World Journal of Gastroenterology 20:35, pages 12709.
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Jon B. Morris, Nora H. Guerrero, Emma E. Furth & Thomas A. Stellato. (1993) Somatostatin attenuates ischemic intestinal injury. The American Journal of Surgery 165:6, pages 676-680.
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George T. Macfarlane & Sandra Macfarlane. (1991) Utilization of pancreatic trypsin and chymotrypsin by proteolytic and nonproteolyticBacteroides fragilis-type bacteria. Current Microbiology 23:3, pages 143-148.
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S.S.C. Rao, C.A. Edwards, C.J. Austen, C. Bruce & N.W. Read. (1988) Impaired colonic fermentation of carbohydrate after ampicillin. Gastroenterology 94:4, pages 928-932.
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E. J. S. Boyd & K. G. Wormsley. (1988) Laboratory tests in the diagnosis of the chronic pancreatic diseases. International journal of pancreatology 3:2-3, pages 101-103.
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JAMES B. HENEGHAN. 1988. Role of the Gut Flora in Toxicity and Cancer. Role of the Gut Flora in Toxicity and Cancer 39 77 .
Osmo H�nninen, Pirjo Lindstr�m-Sepp� & Kai Pelkonen. (1987) Role of gut in xenobiotic metabolism. Archives of Toxicology 60:1-3, pages 34-36.
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Mohamed A. Remtulla, Peter R. Durie & David M. Goldberg. (1986) Stool chymotrypsin activity measured by a spectrophotometric procedure to identify pancreatic disease in infants. Clinical Biochemistry 19:6, pages 341-347.
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T. MIDTVEDT, BODIL CARLSTEDT‐DUKE, T. HØVERSTAD, E. LINGAAS, ELISABETH NORIN, H. SAXERHOLT & M. STEINBAKK. (2008) Influence of peroral antibiotics upon the biotransformatory activity of the intestinal microflora in healthy subjects. European Journal of Clinical Investigation 16:1, pages 11-17.
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K. E. NORIN, B. E. GUSTAFSSON, B. S. LINDBLAD & T. MIDTVEDT. (2008) The Establishment of Some Microflora Associated Biochemical Characteristics in Feces from Children during the First Years of Life. Acta Paediatrica 74:2, pages 207-212.
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Paul Georg Lankisch & Bernhard Lembcke. (1984) Indirect Pancreatic Function Tests: Chemical and Radioisotope Methods. Clinics in Gastroenterology 13:3, pages 717-737.
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P G Lankisch. (1982) Exocrine pancreatic function tests.. Gut 23:9, pages 777-798.
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Michael H. Merson. (1979) Doxycycline and the traveller. Gastroenterology 76:6, pages 1485-1488.
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