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Scandinavian Journal of Gastroenterology Volume 12, 1977 - Issue 7
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Original Article

Impaired Enteric Degradation of Pancreatic Endopeptidases in Antibiotic-Treated Rats

Sven Genell Dept. of Surgery, Malmö General Hospital, University of Lund, and Dept. of Germfree Research, Karolinska Institutet, Stockholm, Sweden
&
Bengt E. Gustafsson Dept. of Surgery, Malmö General Hospital, University of Lund, and Dept. of Germfree Research, Karolinska Institutet, Stockholm, Sweden
Pages 801-809 | Received 15 Mar 1972, Accepted 06 Jun 1977, Published online: 23 Feb 2010

Citations (11)

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B. Carlstedt-Duke, B. E. Gustafsson & T. Midtvedt. (1985) Clindamycin-Induced Alterations in Intestinal Microflora-Associated Characteristics in Rats. Scandinavian Journal of Gastroenterology 20:1, pages 92-98.
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Articles from other publishers (10)

Adam L. Edwinson, Lu Yang, Stephanie Peters, Nikita Hanning, Patricio Jeraldo, Pratik Jagtap, Joshua B. Simpson, Tzu-Yi Yang, Praveen Kumar, Subina Mehta, Asha Nair, Margaret Breen-Lyles, Lakshmikanth Chikkamenahalli, Rondell P. Graham, Benedicte De Winter, Robin Patel, Surendra Dasari, Purna Kashyap, Timothy Griffin, Jun Chen, Gianrico Farrugia, Matthew R. Redinbo & Madhusudan Grover. (2022) Gut microbial β-glucuronidases regulate host luminal proteases and are depleted in irritable bowel syndrome. Nature Microbiology 7:5, pages 680-694.
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Jun-Jie Hou, Xin Wang, Ying Li, Shuai Su, Yu-Ming Wang & Bang-Mao Wang. (2021) The relationship between gut microbiota and proteolytic activity in irritable bowel syndrome. Microbial Pathogenesis 157, pages 104995.
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Shoko Edogawa, Adam L Edwinson, Stephanie A Peters, Lakshmikanth L Chikkamenahalli, Wendy Sundt, Sara Graves, Sakteesh V Gurunathan, Margaret Breen-Lyles, Stephen Johnson, Roy Dyer, Rondell Graham, Jun Chen, Purna Kashyap, Gianrico Farrugia & Madhusudan Grover. (2020) Serine proteases as luminal mediators of intestinal barrier dysfunction and symptom severity in IBS. Gut 69:1, pages 62-73.
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Robin C. Spiller. (2018) Hidden Dangers of Antibiotic Use: Increased Gut Permeability Mediated by Increased Pancreatic Proteases Reaching the Colon. Cellular and Molecular Gastroenterology and Hepatology 6:3, pages 347-348.e1.
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Hongsup Yoon, Monika Schaubeck, Ilias Lagkouvardos, Andreas Blesl, Stephanie Heinzlmeir, Hannes Hahne, Thomas Clavel, Suchita Panda, Christina Ludwig, Bernhard Kuster, Chaysavanh Manichanh, Patrizia Kump, Dirk Haller & Gabriele Hörmannsperger. (2018) Increased Pancreatic Protease Activity in Response to Antibiotics Impairs Gut Barrier and Triggers Colitis. Cellular and Molecular Gastroenterology and Hepatology 6:3, pages 370-388.e3.
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Jonna Jalanka, Anne Salonen, Jarkko Salojärvi, Jarmo Ritari, Outi Immonen, Luca Marciani, Penny Gowland, Caroline Hoad, Klara Garsed, Ching Lam, Airi Palva, Robin C Spiller & Willem M de Vos. (2015) Effects of bowel cleansing on the intestinal microbiota. Gut 64:10, pages 1562-1568.
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David Tooth, Klara Garsed, Gulzar Singh, Luca Marciani, Ching Lam, Imogen Fordham, Annie Fields, Rawinder Banwait, Melanie Lingaya, Robert Layfield, Maggie Hastings, Peter Whorwell & Robin Spiller. (2014) Characterisation of faecal protease activity in irritable bowel syndrome with diarrhoea: origin and effect of gut transit. Gut 63:5, pages 753-760.
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Xiaofa Qin. (2014) May bacterial or pancreatic proteases play a critical role in inflammatory bowel disease?. World Journal of Gastroenterology 20:35, pages 12709.
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T. Midtvedt. 1989. The Influence of Antibiotics on the Host-Parasite Relationship III. The Influence of Antibiotics on the Host-Parasite Relationship III 209 215 .
Jerome E. Bakke, Jan-Åke Gustafsson & Bengt E. Gustafsson. (1980) Metabolism of Propachlor by the Germfree Rat. Science 210:4468, pages 433-435.
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