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Original Article

Methyl-Prostaglandin E2 Analogues for Healing of Gastro-Duodenal Ulcers

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Pages 155-159 | Received 21 Aug 1977, Accepted 10 Oct 1977, Published online: 23 Feb 2010

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Read on this site (8)

A. Aly. (1987) Prostaglandins in Clinical Treatment of Gastroduodenal Mucosal Lesions: A Review. Scandinavian Journal of Gastroenterology 22:sup137, pages 43-49.
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Stanislaw J. Konturek. (1985) Gastric Cytoprotection. Scandinavian Journal of Gastroenterology 20:5, pages 543-553.
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P. Sharon, F. Cohen, A. Zifroni, F. Karmeli, M. Ligumsky & D. Rachmilewitz. (1983) Prostanoid Synthesis by Cultured Gastric and Duodenal Mucosa: Possible Role in the Pathogenesis of Duodenal Ulcer. Scandinavian Journal of Gastroenterology 18:8, pages 1045-1049.
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J. Myren. (1983) The Natural History of Peptic Ulcer—Views in the 1980s. Scandinavian Journal of Gastroenterology 18:8, pages 993-997.
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K. Gibiński, J. Rybicka, A. Nowak & K. Czarnecka. (1982) Seasonal Occurrence of Abdominal Pain and Endoscopic Findings in Patients with Gastric and Duodenal Ulcer Disease. Scandinavian Journal of Gastroenterology 17:4, pages 481-485.
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H. Ruppin, B. Person, A. Robert & W. Domschke. (1981) Gastric Cytoprotection in Man by Prostaglandin E2. Scandinavian Journal of Gastroenterology 16:5, pages 647-652.
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Kornel Gibinski. (1981) Some problems in modern anti-ulcer drug evaluation: A comparison of four gastric acid suppressors. Current Medical Research and Opinion 7:8, pages 516-519.
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S. J. Konturek, J. S. Swierczek, N. Kwiecien, W. Obtułowicz, E. Sito & J. Oleksy. (1979) Effect of Orally Administered 15(R)-15-Methyl Prostaglandin E2 and/or an Anticholinergic Drug on Meal-induced Gastric Acid Secretion and Serum Gastrin Level in Patients with Duodenal Ulcers. Scandinavian Journal of Gastroenterology 14:7, pages 813-819.
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Articles from other publishers (44)

J. S. DIXON, P. R. WORTHINGTON, J. G. MILLS & J. R. WOOD. (2007) Geographical differences of gastric ulcer healing rate in patients treated with ranitidine or placebo. Alimentary Pharmacology & Therapeutics 3:4, pages 353-365.
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S. J. Konturek. 1988. Eicosanoids and the Gastrointestinal Tract. Eicosanoids and the Gastrointestinal Tract 46 74 .
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P. Demol. 1988. Prostaglandins and Leukotrienes in Gastrointestinal Diseases. Prostaglandins and Leukotrienes in Gastrointestinal Diseases 90 104 .
Dov Wengrower, Alexander Fich, Eran Goldin, Rami Eliakim, Moshe Ligumsky & Daniel Rachmilewitz. (1987) Cytoprotective doses of arbacet with minimal antisecretory properties are not effective in duodenal ulcer healing. Digestive Diseases and Sciences 32:8, pages 857-860.
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Donald E. Wilson. (1987) Antisecretory and mucosal protective actions of misoprostol. The American Journal of Medicine 83:1, pages 2-8.
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S. J. Konturek, N. Kwiecien, T. Radecki & J. Oleksy. 1987. Side-Effects of Anti-Inflammatory Drugs. Side-Effects of Anti-Inflammatory Drugs 123 132 .
S. K. LAM. (2008) Prostaglandins for duodenal ulcer and gastric ulcer. Journal of Gastroenterology and Hepatology 1:6, pages 471-481.
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Hanns-Gerd Dammann, Wolfram Hüttemann, Horst Dieter Kalek, Heinz Georg Rohner & Bernd Simon. (1986) Comparative clinical trial of enprostil and ranitidine in the treatment of gastric ulcer. The American Journal of Medicine 81:2, pages 80-84.
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Susumu OKABE, Hiroshi JINO & Akito NISHIDA. (1986) Effects of 15(R)-15-Methyl Prostaglandin E2 (Arbaprostil) on Gastric Secretion and Various Gastric Lesions Induced in Rats. Japanese Journal of Pharmacology 40:2, pages 329-337.
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H. J. Lenz, S. Brozinsky, M. A. Koss, D. L. Hogan, M. L. Scheinbaum & J. I. Isenberg. (1986) Effect of 11R, 16, 16-trimethyl prostaglandin E2 on meal-stimulated gastric acid secretion in duodenal ulcer subjects. European Journal of Clinical Pharmacology 31:3, pages 281-284.
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Jorge E. Valenzuela & Hartley Cohen. 1986. Topics in Clinical Pharmacology and Therapeutics. Topics in Clinical Pharmacology and Therapeutics 151 174 .
Norbert Charlet, Hugo E. Gallo‐Torres, Yves Bounameaux & Robert J. Wills. (2013) Prostaglandins and the Protection of the Gastroduodenal Mucosa in Humans: A Critical Review. The Journal of Clinical Pharmacology 25:8, pages 564-582.
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C.J. Hawkey & D.S. Rampton. (1985) Prostaglandins and the gastrointestinal mucosa: Are they important in its function, disease, or treatment?. Gastroenterology 89:5, pages 1162-1188.
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F. P. Brooks. (1985) The pathophysiology of peptic ulcer disease. Digestive Diseases and Sciences 30:S11, pages 15S-29S.
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A. Robert, P.A. Aristoff, M.G. Wendling, F.A. Kimball, W.J. MillerJr.Jr. & R.R. Gorman. (1985) Cytoprotective and antisecretory properties of a non-diarrheogenic and non-uterotonic prostacyclin analog: U-68, 215. Prostaglandins 30:4, pages 619-649.
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H. El-Bayer, L. Steel, E. Montcalm, E. Danquenchin-Dorval, A. Dubois & T. Shea-Donohue. (1985) The role of endogenous prostaglandins in the regulation of gastric secretion in rhesus monkeys. Prostaglandins 30:3, pages 401-417.
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Max M. Cohen, Lorenna Clark, Lynn Armstrong & Joseph D'Souza. (1985) Reduction of aspirin-induced fecal blood loss with low-dose misoprostol tablets in man. Digestive Diseases and Sciences 30:7, pages 605-611.
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D. Lee & D. Dvornik. (1985) Etodolac: Effect on prostaglandin concentrations in gastric mucosa of rats. Life Sciences 36:12, pages 1157-1162.
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Andrzej Tarnawski. (1985) Prevention and treatment of gastrointestinal mucosal injury with cytoprotective agents. Medical Journal of Australia 142:S3.
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G. N. J. Tijtgat. 1985. Peptic Ulcer Disease: Basic and Clinical Aspects. Peptic Ulcer Disease: Basic and Clinical Aspects 143 153 .
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Donald E. Wilson, M.D. Hulya Levendoglu, M.D. Andrea Adams & Elaine Ramsamooj. (1984) A new PGE1 analogue (CL115,574) III. Effects on gastric acid and mucus secretion in man. Prostaglandins 28:1, pages 5-11.
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S. J. Konturek. 1984. IUPHAR 9th International Congress of Pharmacology London 1984. IUPHAR 9th International Congress of Pharmacology London 1984 341 344 .
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S.S. Kerwar. (1983) Pharmacologic properties of fenbufen. The American Journal of Medicine 75:4, pages 62-69.
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B. Kollberg & P. Slezak. (1982) The effect of prostaglandin E2 on duodenal ulcer healing. Prostaglandins 24:4, pages 527-536.
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J. Silvola, M. Kangasaho, O. Tokola & H. Vapaatalo. (1982) Effects of nonsteroidal anti-inflammatory drugs on rat gastric mucosal phosphodiesterase activity. Agents and Actions 12:4, pages 516-520.
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Harvey H. Sigman & Anton Gillich. (1982) Effects of antacids, cimetidine, and 16, 16-dimethyl prostaglandin E2 on acute gastric erosions in a spinal rat. Digestive Diseases and Sciences 27:3, pages 220-224.
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