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Scandinavian Journal of Gastroenterology Volume 14, 1979 - Issue 5
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Original Article

Inhibition of Gastric Acid Secretion by Pirenzepine (LS 519) in Man

R. Stockbrügger Division of Gastroenterology, Dept. of Medicine II, Sahlgren's Hospital. University of Gothenburg, Gothenburg, Sweden, and Dept. of Biochemistry, Dr. Karl Thomae GmbH, Biberach, West Germany
,
B. Jaup Division of Gastroenterology, Dept. of Medicine II, Sahlgren's Hospital. University of Gothenburg, Gothenburg, Sweden, and Dept. of Biochemistry, Dr. Karl Thomae GmbH, Biberach, West Germany
,
R. Hammer Division of Gastroenterology, Dept. of Medicine II, Sahlgren's Hospital. University of Gothenburg, Gothenburg, Sweden, and Dept. of Biochemistry, Dr. Karl Thomae GmbH, Biberach, West Germany
&
G. Dotevall Division of Gastroenterology, Dept. of Medicine II, Sahlgren's Hospital. University of Gothenburg, Gothenburg, Sweden, and Dept. of Biochemistry, Dr. Karl Thomae GmbH, Biberach, West Germany
Pages 615-620 | Received 28 Sep 1978, Accepted 20 Mar 1979, Published online: 23 Feb 2010

Citations (19)

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S. Emås. (1987) Medical Principles for Treatment of Peptic Ulcer. Scandinavian Journal of Gastroenterology 22:sup137, pages 28-32.
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B. H. Jaup, H. Abrahamsson, R. W. Stockbruegger, K. Rosengren & G. Dotevall. (1985) Effect of Selective and Non-Selective Antimuscarinics on Rectosigmoid Motility and Gastrointestinal Transit. Scandinavian Journal of Gastroenterology 20:9, pages 1101-1109.
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S. Nishimura, R. Laugier & H. Sarles. (1985) Action of Pirenzepine, A New Muscarinic Antagonist Drug, on Human Pancreatic Secretion. Scandinavian Journal of Gastroenterology 20:8, pages 990-994.
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R. W. Stockbruegger, S. Seeberg, L. Hellner, B. H. Jaup & G. Dotevall. (1984) Intragastric Bacteria and Nitrite after Short-Term Treatment with Different Doses of Antimuscarinic Drugs. Scandinavian Journal of Gastroenterology 19:1, pages 14-23.
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R. Corinaldesi, M. Miglioli, S. Daniotti, V. Stanghellini, E. Borghi & L. Barbara. (1981) Inhibition by Pirenzepine of Nocturnal Gastric Acid Secretion in Duodenal Ulcer Patients. Scandinavian Journal of Gastroenterology 16:7, pages 929-931.
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B. H. Jaup & G. Dotevall. (1981) The Effect of Pirenzepine and L-Hyoscyamine on Gastric Emptying and Salivary Secretion in Healthy Volunteers. Scandinavian Journal of Gastroenterology 16:6, pages 769-773.
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M. Tatsuta, T. Itoh, S. Okuda, H. Tamura, M. Baba & H. Yamamura. (1981) Inhibition of Gastrin Secretion by Pirenzepine (LS 519) in Treatment of Gastric Ulcer. Scandinavian Journal of Gastroenterology 16:2, pages 269-271.
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Articles from other publishers (12)

Takahiro Suzuki, Tomohiro Higuchi, Takuma Kagami, Takahiro Uotani, Mihoko Yamade, Shinya Tani, Yasushi Hamaya, Moriya Iwaizumi, Satoshi Osawa, Ken Sugimoto, Hiroaki Miyajima & Takahisa Furuta. (2021) Effects of pirenzepine on vonoprazan-induced gastric acid inhibition and hypergastrinemia. European Journal of Clinical Pharmacology 77:7, pages 971-978.
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F. J. TEIXEIRA-NETO, W. N. McDONELL, W. D. BLACK, W. HARRIS & L. GROVUM. (2012) Effects of muscarinic receptor antagonists on acetylcholine-induced contractions of jejunal smooth muscle in horses. Journal of Veterinary Pharmacology and Therapeutics 35:4, pages 313-318.
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Tomoko Hayano, Akihiko Shimizu, Yasuhiro Ikeda, Takeshi Yamamoto, Toshihiko Yamagata, Takeshi Ueyama, Yuji Furutani & Masunori Matsuzaki. (1999) Paradoxical effects of pirenzepine on parasympathetic activity in chronic heart failure and control. International Journal of Cardiology 68:1, pages 47-56.
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Sean J. Mulvihill, Theodore N. Pappas & Haile T. Debas. (1989) Characterization ofin vivo acid secretory responses of rabbit with comparison to dog and rat. Digestive Diseases and Sciences 34:6, pages 895-904.
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Robert Roskoski Jr.. (1987) Cholinergic Muscarinic Receptor Characterization and Regulation in Tissues Innervated by the Autonomic Nervous System. Journal of Basic and Clinical Physiology and Pharmacology 6:1, pages 1-60.
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Humeida A. El-Obeild, Salim A. Babhair & Abdullah A. Al-Badr. 1987. 445 506 .
Richard Magous, Bruno Baudiere & Jean-Pierre Bali. (1985) Muscarinic receptors in isolated gastric fundic mucosal cells binding-activity relationships. Biochemical Pharmacology 34:13, pages 2269-2274.
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Francesco Narducci, Gabrio Bassotti, Sergio Daniotti, Piero Del Soldato, Maria Antonia Pelli & Antonio Morelli. (1985) Identification of muscarinic receptor subtype mediating colonic response to eating. Digestive Diseases and Sciences 30:2, pages 124-128.
Crossref
R. W. Stockbrügger, B. H. Jaup, W. Abrahamsson & G. Dotevall. 1985. Muscarinic Receptor Subtypes in the GI Tract. Muscarinic Receptor Subtypes in the GI Tract 75 82 .
G.N.J. TYTGAT, W. HAMEETEMAN & G.H. VAN OLFFEN. (1984) Sucralfate, Bismuth Compounds, Substituted Benzimidazoles, Trimipramine and Pirenzepine in the Short- and Long-term Treatment of Duodenal Ulcer. Clinics in Gastroenterology 13:2, pages 543-568.
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Robert G. Pendleton, Michael Williams, Christine Chung, Patricia Cook & Edwin Risley. (1984) Comparison of central gastric antisecretory effects of desmethylimipramine, doxepin and pirenzepine in rats. Naunyn-Schmiedeberg's Archives of Pharmacology 326:3, pages 210-214.
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M.J. DALY, JANET M. HUMPHRAY & R. STABLES. (2012) EFFECTS OF H 2 ‐RECEPTOR ANTAGONISTS AND ANTICHOLINOCEPTOR DRUGS ON GASTRIC AND SALIVARY SECRETION INDUCED BY BETHANECHOL IN THE ANAESTHETIZED DOG . British Journal of Pharmacology 76:3, pages 361-365.
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