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Scandinavian Journal of Gastroenterology Volume 16, 1981 - Issue 4
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Original Article

Clinical Effect of Metronidazole and Sulfasalazine on Crohn's Disease in Relation to Changes in the Fecal Flora

A. Krook Dept. of Internal Medicine, Division of Gastroenterology, and the Dept. of Clinical Microbiology and Immunology, Central County Hospital, Örebro, Sweden
,
G. Järnerot Dept. of Internal Medicine, Division of Gastroenterology, and the Dept. of Clinical Microbiology and Immunology, Central County Hospital, Örebro, Sweden
&
D. Danielsson Dept. of Internal Medicine, Division of Gastroenterology, and the Dept. of Clinical Microbiology and Immunology, Central County Hospital, Örebro, Sweden
Pages 569-575 | Received 29 Jul 1980, Accepted 23 Sep 1980, Published online: 22 Feb 2010

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B. Ursing, S. Portinson & C. E. Nord. (1988) Influence of a Vegetarian Diet on the Faecal Microflora of Patients with Crohn's Disease. Microbial Ecology in Health and Disease 1:3, pages 205-208.
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H. Sandberg Gertzen, J. Kjellander, B. Sundberg-Gillar & G. Jarrnerot. (1985) In Vitro Effects of Sulphasalazine, Azodisal Sodium, and Their Metabolites on Clostridium difficile and Some Other Faecal Bacteria. Scandinavian Journal of Gastroenterology 20:5, pages 607-612.
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Articles from other publishers (23)

Marc Ferrante, Lieven Pouillon, Míriam Mañosa, Edoardo Savarino, Matthieu Allez, Christina Kapizioni, Naila Arebi, Michele Carvello, Pär Myrelid, Annemarie C De Vries, Gabriele Dragoni, Mariangela Allocca, Nurulamin M Noor, Gabriele Bislenghi, Nassim Hammoudi, Bram Verstockt, Steven Brown, Melissa Oliveira Cunha, Willem Bemelman, Gianluca Pellino, Paulo Gustavo Kotze, Pauline Rivière, Yves Panis & Eugeni Domènech. (2023) Results of the Eighth Scientific Workshop of ECCO: Prevention and Treatment of Postoperative Recurrence in Patients With Crohn’s Disease Undergoing an Ileocolonic Resection With Ileocolonic Anastomosis. Journal of Crohn's and Colitis 17:11, pages 1707-1722.
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S. B. Debast, M. P. Bauer, I. M. J. G. Sanders, M. H. Wilcox & E. J. Kuijper. (2013) Antimicrobial activity of LFF571 and three treatment agents against Clostridium difficile isolates collected for a pan-European survey in 2008: clinical and therapeutic implications. Journal of Antimicrobial Chemotherapy 68:6, pages 1305-1311.
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Wee-Chian Lim & Stephen Hanauer. 1996. Cochrane Database of Systematic Reviews. Cochrane Database of Systematic Reviews.
J. Freeman, M. P. Bauer, S. D. Baines, J. Corver, W. N. Fawley, B. Goorhuis, E. J. Kuijper & M. H. Wilcox. (2010) The Changing Epidemiology of Clostridium difficile Infections . Clinical Microbiology Reviews 23:3, pages 529-549.
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S. D. Baines, R. O'Connor, J. Freeman, W. N. Fawley, C. Harmanus, P. Mastrantonio, E. J. Kuijper & M. H. Wilcox. (2008) Emergence of reduced susceptibility to metronidazole in Clostridium difficile. Journal of Antimicrobial Chemotherapy 62:5, pages 1046-1052.
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Paul A Rufo & Athos Bousvaros. (2006) Current Therapy of Inflammatory Bowel Disease in Children. Pediatric Drugs 8:5, pages 279-302.
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Philippe Marteau & Fergus Shanahan. 2005. Inflammatory Bowel Disease: From Bench to Bedside. Inflammatory Bowel Disease: From Bench to Bedside 573 585 .
Philippe Marteau & Fergus Shanahan. 2003. Inflammatory Bowel Disease: From Bench to Bedside. Inflammatory Bowel Disease: From Bench to Bedside 573 585 .
Heiko C. Rath, Michael Schultz, René Freitag, Levinus A. Dieleman, Fengling Li, Hans-Jörg Linde, Jürgen Schölmerich & R. Balfour Sartor. (2001) Different Subsets of Enteric Bacteria Induce and Perpetuate Experimental Colitis in Rats and Mice. Infection and Immunity 69:4, pages 2277-2285.
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R.B. Sartor. (1997) The influence of normal microbial flora on the development of chronic mucosal inflammation. Research in Immunology 148:8-9, pages 567-576.
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R. Balfour Sartor. (1997) Enteric Microflora in IBD: Pathogens or Commensals?. Inflammatory Bowel Diseases 3:3, pages 230-235.
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Paul Rutgeerts, Martin Hiele, Karel Geboes, Marc Peeters, Freddy Penninckx, Raymond Aerts & Raymond Kerremans. (1995) Controlled trial of metronidazole treatment for prevention of crohn's recurrence after ileal resection. Gastroenterology 108:6, pages 1617-1621.
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GUNNAR WICKBOM, DAN DANIELSSON, SOON-OK CHA, INGEGERD ALRIKSSON, GUNNAR JÄRNEROT & JAN KJELLANDER. (1993) Formula diet is a preventive factor in experimentally induced ileal ulcers in rats. A bacteriological study. APMIS 101:7-12, pages 565-571.
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Edward W. NelsonJr.Jr., David E. Bright & Luis F. Villar. (1990) Closure of refractory perineal Crohn's lesion. Digestive Diseases and Sciences 35:12, pages 1561-1565.
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Rial D. Rolfe. 1989. Anaerobic Infections in Humans. Anaerobic Infections in Humans 679 690 .
Michael J. Hudson. 1987. Recent Advances in Anaerobic Bacteriology. Recent Advances in Anaerobic Bacteriology 60 71 .
JL Shaffer, A. Kershaw & JB Houston. (2012) Disposition of metronidazole and its effects on sulphasalazine metabolism in patients with inflammatory bowel disease.. British Journal of Clinical Pharmacology 21:4, pages 431-435.
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N. S. Ambrose, R. N. Allan, M. R. B. Keighley, D. W. Burdon, Denise Youngs, P. Barnes & J. E. Lennard-Jones. (1985) Antibiotic therapy for treatment in relapse of intestinal Crohn's disease. Diseases of the Colon & Rectum 28:2, pages 81-85.
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R J Chiodini, H J Van Kruiningen, W R Thayer, J A Coutu & R S Merkal. (1984) In vitro antimicrobial susceptibility of a Mycobacterium sp. isolated from patients with Crohn's disease. Antimicrobial Agents and Chemotherapy 26:6, pages 930-932.
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SYDNEY M. FINEGOLD, GLENN E. MATHISEN & W. LANCE GEORGE. 1983. Human Intestinal Microflora in Health and Disease. Human Intestinal Microflora in Health and Disease 355 446 .
Bo Ursing, Thor Alm, Franz Bárány, Ingemar Bergelin, Karin Ganrot-Norlin, Jürgen Hoevels, Bernhard Huitfeldt, Gunnar Jarnerot, Urban Krause, Aud Krook, Björn Lindström, Örjan Nordle & Anders Rosén. (1982) A Comparative Study of Metronidazole and Sulfasalazine for Active Crohn's Disease: The Cooperative Crohn's Disease Study in Sweden. Gastroenterology 83:3, pages 550-562.
Crossref
Anders Rosén, Bo Ursing, Thor Alm, Franz Bárány, Ingemar Bergelin, Karin Ganrot-Norlin, Jürgen Hoevels, Bernhard Huitfeldt, Gunnar Järnerot, Urban Krause, Aud Krook, Björn Lindström & Örjan Nordle. (1982) A Comparative Study of Metronidazole and Sulfasalazine for Active Crohn's Disease: The Cooperative Crohn's Disease Study in Sweden. Gastroenterology 83:3, pages 541-549.
Crossref
Joseph B. Kirsner & Roy G. Shorter. (1982) Recent Developments in Nonspecific Inflammatory Bowel Disease. New England Journal of Medicine 306:13, pages 775-785.
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