3
Views
60
CrossRef citations to date
0
Altmetric
Original article

Prostanoid Synthesis by Cultured Gastric and Duodenal Mucosa: Possible Role in the Pathogenesis of Duodenal Ulcer

, , , , &
Pages 1045-1049 | Received 29 Nov 1982, Accepted 16 Feb 1983, Published online: 19 Feb 2010

Keep up to date with the latest research on this topic with citation updates for this article.

Read on this site (13)

A. Mertz-nielsen, J. Hillingsø, H. Frøkiær, K. Bukhave & J. Rask-madsen. (1996) Gastric Bicarbonate Secretion and Release of Prostaglandin E2 Are Increased in Duodenal Ulcer Patients But Not in Helicobacter pylori-Positive Healthy Subjects. Scandinavian Journal of Gastroenterology 31:1, pages 38-43.
Read now
G. Silecchia, E. Spaziani, E. Guarino, T. Neri, E. Grasso, P. Mariani, A. Materia, A. Genco & N. Basso. (1994) Effect of Nizatidine versus Ranitidine on Gastric Intraluminal Prostaglandin Release in Duodenal Ulcer Patients. Scandinavian Journal of Gastroenterology 29:sup206, pages 8-13.
Read now
Z. Ackerman, F. Karmeli, M. Ligumsky & D. Rachmilewitz. (1990) Enhanced Gastric and Duodenal Platelet-Activating Factor and Leukotriene Generation in Duodenal Ulcer Patients. Scandinavian Journal of Gastroenterology 25:9, pages 925-934.
Read now
A. Cohen, K. G. Tolman, G. P. Lewis, S. Brown, A. Van Horn, G. H. McCormack & D. M. Simon. (1989) The Antigastrolesive Activity of Rioprostil, a 16-Methyl Prostaglandin-E! Analogue in Healthy Volunteers. Scandinavian Journal of Gastroenterology 24:sup164, pages 81-91.
Read now
M. Ligumsky, D. Wengrower, F. Karmeli & D. Rachmilewitz. (1988) Somatostatin Release by Human Gastric Mucosa Studies in Peptic Ulcer Disease and Pernicious Anemia. Scandinavian Journal of Gastroenterology 23:6, pages 687-690.
Read now
Andreas Aly, Krister Gréen & Catja Johansson. (1987) Prostaglandin Synthesis in the Human Gastrointestinal Mucosa. Scandinavian Journal of Gastroenterology 22:sup127, pages 35-38.
Read now
A. Aly. (1987) Prostaglandins in Clinical Treatment of Gastroduodenal Mucosal Lesions: A Review. Scandinavian Journal of Gastroenterology 22:sup137, pages 43-49.
Read now
J. R. Crampton, L. C. Gibbons & W. D. W. Rees. (1987) Simultaneous Measurement of In Vitro Gastroduodenal Prostaglandin E2 Synthesis and Degradation in Peptic Ulcer Disease. Scandinavian Journal of Gastroenterology 22:4, pages 425-430.
Read now
J.-R. Malagelada. (1986) Prostaglandin Metabolism in Peptic Ulcer Disease. Scandinavian Journal of Gastroenterology 21:sup125, pages 136-143.
Read now
E. F. Stange, G. Preclik & H. Ditschuneit. (1986) Prostaglandin Biosynthesis in Gastroduodenal Mucosa: Methodological Difficulties and Their Implications. Scandinavian Journal of Gastroenterology 21:sup125, pages 121-127.
Read now
Stanislaw J. Konturek. (1985) Gastric Cytoprotection. Scandinavian Journal of Gastroenterology 20:5, pages 543-553.
Read now
D. Branski, P. Sharon, F. Karmeli & D. Rachmilewitz. (1984) Effect of Cimetidine on Human Gastric and Duodenal Prostanoid Synthesis. Scandinavian Journal of Gastroenterology 19:4, pages 457-460.
Read now

Articles from other publishers (47)

Camille Pochard, Jacques Gonzales, Anne Bessard, Maxime M. Mahe, Arnaud Bourreille, Nicolas Cenac, Anne Jarry, Emmanuel Coron, Juliette Podevin, Guillaume Meurette, Michel Neunlist & Malvyne Rolli-Derkinderen. (2021) PGI2 Inhibits Intestinal Epithelial Permeability and Apoptosis to Alleviate Colitis. Cellular and Molecular Gastroenterology and Hepatology 12:3, pages 1037-1060.
Crossref
Lance F. Brown & Donald E. Wilson. (1999) Gastroduodenal ulcers: Causes, diagnosis, prevention and treatment. Comprehensive Therapy 25:1, pages 30-38.
Crossref
Tetsuo Arakawa, Toshio Watanabe, Takashi Fukuda, Kazuhide Higuchi, Osamu Takaishi, Katsuya Yamasaki, Kenzo Kobayashi & Andrzej Tarnawski. (1996) Indomethacin treatment during initial period of acetic acid-induced rat gastric ulcer healing promotes persistent polymorphonuclear cell-infiltration and increases future ulcer recurrence. Digestive Diseases and Sciences 41:10, pages 2055-2061.
Crossref
Tetsuo Arakawa, Toshio Watanabe, Takashi Fukuda, Katsuya Yamasaki & Kenzo Kobayashi. (1995) Rebamipide, novel prostaglandin-inducer, accelerates healing and reduces relapse of acetic acid-induced rat gastric ulcer comparison with cimetidine. Digestive Diseases and Sciences 40:11, pages 2469-2472.
Crossref
A Mertz-Nielsen, O Eskerod, K Bukhave & J Rask-Madsen. (1995) Misoprostol inhibits gastric mucosal release of endogenous prostaglandin E2 and thromboxane B2 in healthy volunteers.. Gut 36:4, pages 511-515.
Crossref
Y. Denizot, A. Najid & M. Rigaud. (1993) Effects of eicosanoid metabolism inhibitors on growth of a human gastric tumour cell line (HGT). Cancer Letters 73:1, pages 65-71.
Crossref
G. Preclik, E.F. Strange & H. Ditschuneit. (1992) PGE2 secretion from organ cultured gastric mucosa: Correlation with cyclooxygenase activity and endogenous substrate release. Prostaglandins 43:6, pages 545-558.
Crossref
A Ahmed, P R Salmon, C R Cairns, M Hobsley & J R Hoult. (1992) Eicosanoid synthesis in duodenal ulcer disease: decrease in leukotriene C4 by colloidal bismuth subcitrate.. Gut 33:2, pages 159-163.
Crossref
E. GOLDIN, F. KARMELI & D. RACHMILEWITZ. (2007) Efficacy of misoprostol and ranitidine in the prevention of duodenal ulcer relapse and its correlation with endogenous gastric prostanoid synthesis. Alimentary Pharmacology & Therapeutics 5:2, pages 173-180.
Crossref
G. Preclik, E.F. Stange, D. Arnold & H. Ditschuneit. (1991) In vitro effects of arachidonic acid on the prostaglandin synthesizing system in gastric mucosa. Prostaglandins 41:4, pages 359-373.
Crossref
Klaus Bukhave, Jorgen Rask-Madsen, Daniel L. Hogan, Michael A. Koss & Jon I. Isenberg. (1990) Proximal duodenal prostaglandin E2 release and mucosal bicarbonate secretion are altered in patients with duodenal ulcer. Gastroenterology 99:4, pages 951-955.
Crossref
Mark Feldman. (1990) Southwestern Internal Medicine Conference: Prostaglandins and Gastric Ulcers: From Seminal Vesicle to Misoprostol (Cytotec®). The American Journal of the Medical Sciences 300:2, pages 116-132.
Crossref
S. Kapicioglu, D.B. McNamara, M.Y. Vacarella, P.J. Kadowitz, S. Hoda & A. Ertan. (1990) Prostaglandin E2 formation by rat gastroduodenal tissue following intragastric acid perfusion. Prostaglandins, Leukotrienes and Essential Fatty Acids 39:4, pages 277-281.
Crossref
M. Moran & P. Nicholson. (1990) Prostaglandin deficiency. Prostaglandins, Leukotrienes and Essential Fatty Acids 39:1, pages 83-89.
Crossref
A.S. Taha, A.W. Mckinlay, R. Upadhyay, R. Kelly, R.I. Russell & J.O. Hunter. (1989) PROSTAGLANDINS AND CAMPYLOBACTER PYLORI. The Lancet 334:8666, pages 800-801.
Crossref
S Pugh, S E Williams, M R Lewin, M Ishaque, T P Barton, K Bose, K D Bardhan & C G Clark. (1989) Duodenal and antral mucosal prostaglandin E2 synthesis in a study of normal subjects and all stages of duodenal ulcer disease treated by H2 receptor antagonists.. Gut 30:2, pages 161-165.
Crossref
A.C. Flind, A.S. Taha, P. Boothman, P. Holland, A.W. Mckinlay, R. Upadhyay, R.W. Kelly, F.D. Lee & R.I. Russell. (1989) DUODENAL ULCER AND CAMPYLOBACTER PYLORI,. The Lancet 333:8633, pages 333-334.
Crossref
Donald E. Wilson. 1989. Gastric Cytoprotection. Gastric Cytoprotection 169 186 .
TETSUO ARAKAWA, HAJIME NAKAMURA, HIROSHI SATOH, TAKASHI FUKUDA, HIROYUKI SAKUMA & KENZO KOBOYASHI. (2008) Deficiency of endogenous prostanoids in gastric and duodenal ulcer diseases. Journal of Gastroenterology and Hepatology 3:5, pages 441-449.
Crossref
István Dobó, Károly Tihanyi, János Banai, Imre Szántó & Imre Rózsa. (1988) Mucosal prostaglandin levels of the gastric stump. Gastroenterologia Japonica 23:5, pages 514-520.
Crossref
E. GOLDIN, R. STALNIKOWICZ, D. WENGROWER, R. ELIAKIM, A. FICH, M. LIGUMSKY, F. KARMELI & D. RACHMILEWITZ. (2007) No correlation between indomethacin‐induced gastroduodenal damage and inhibition of gastric prostanoid synthesis. Alimentary Pharmacology & Therapeutics 2:4, pages 369-375.
Crossref
Kenneth S. Nord. (1988) Peptic Ulcer Disease in the Pediatric Population. Pediatric Clinics of North America 35:1, pages 117-140.
Crossref
S. J. Konturek. 1988. Eicosanoids and the Gastrointestinal Tract. Eicosanoids and the Gastrointestinal Tract 46 74 .
E. J. S. Boyd & K. G. Wormsley. 1988. Prostaglandins and Leukotrienes in Gastrointestinal Diseases. Prostaglandins and Leukotrienes in Gastrointestinal Diseases 227 232 .
B. Riechert, V. Schumpelick & B. Kremer. (1987) Ulcusrisiko nach Umwandlungsoperationen von B-I-M�gen in refluxverh�tende Reparationsverfahren ?eine tierexperimentelle StudieExperimental study on the ulcer risk after Billroth-I-resections. Langenbecks Archiv f�r Chirurgie 371:4, pages 253-262.
Crossref
Edward D. CorboyJr.Jr., George A. Clay, Dan T. Fakouhi & Edward A. Swabb. (1987) Appendix: Humanitarian use of misoprostol in severe refractory upper gastrointestinal disease. The American Journal of Medicine 83:1, pages 49-52.
Crossref
Donald E. Wilson. (1987) Antisecretory and mucosal protective actions of misoprostol. The American Journal of Medicine 83:1, pages 2-8.
Crossref
Arthur R. Euler, Guido Tytgat, Joaquin Berenguer, Harold Brunner, David R. Wood, Janice L. Lookabaugh & Tuan D. Phan. (1987) Failure of a cytoprotective dose of arbaprostil to heal acute duodenal ulcers. Gastroenterology 92:3, pages 604-607.
Crossref
Mark Feldman. (1987) Bicarbonate, Acid, and Duodenal Ulcer. New England Journal of Medicine 316:7, pages 408-409.
Crossref
S J Konturek, N Kwiecien, W Obtulowicz, B Kopp & J Oleksy. (1986) Double blind controlled study on the effect of sucralfate on gastric prostaglandin formation and microbleeding in normal and aspirin treated man.. Gut 27:12, pages 1450-1456.
Crossref
S. K. LAM. (2008) Prostaglandins for duodenal ulcer and gastric ulcer. Journal of Gastroenterology and Hepatology 1:6, pages 471-481.
Crossref
Henri Navert. (1986) Treatment of gastric ulcer with enprostil. The American Journal of Medicine 81:2, pages 75-79.
Crossref
Peter Bright-Asare. (1986) Treatment of duodenal ulcer with enprostil, a prostaglandin E2 analogue. The American Journal of Medicine 81:2, pages 64-68.
Crossref
. (2012) POSTER COMMUNICATIONS. British Journal of Pharmacology 88:S1.
Crossref
Richard Hunt. (1986) An alternative view of the stomach—measurement and mucosal defense. Gastrointestinal Endoscopy 32:2, pages 118-119.
Crossref
Daniel Rachmilewitz, Moshe Ligumsky, Alexander Fich, Eran Goldin, Abraham Eliakim & Fanny Karmeli. (1986) Role of endogenous gastric prostanoids in the pathogenesis and therapy of duodenal ulcer. Gastroenterology 90:4, pages 963-969.
Crossref
Esam Z. Dajani. (1986) Is peptic ulcer a prostaglandin deficiency disease?. Human Pathology 17:2, pages 106-107.
Crossref
Peter Bright-Asare, Stephen J. Sontag, Ronald J. Gould, Douglas L. Brand & Walter M Roufail. (1986) Efficacy of misoprostol (twice daily dosage) in acute healing of duodenal ulcer. Digestive Diseases and Sciences 31:S2, pages 63S-67S.
Crossref
Juan-R. Malagelada, David A. Ahlquist & S. Christopher Moore. (1986) Defects in prostaglandin synthesis and metabolism in ulcer disease. Digestive Diseases and Sciences 31:S2, pages 20S-27S.
Crossref
S. J. Sontag, P. A. Mazure, J. F. Pontes, S. G. Beker & E. Z. Dajani. (1985) Misoprostol in the treatment of duodenal ulcer. Digestive Diseases and Sciences 30:S11, pages 159S-163S.
Crossref
S. J. Konturek. (1985) Prostaglandins in pathophysiology of peptic ulcer disease. Digestive Diseases and Sciences 30:S11, pages 105S-108S.
Crossref
K Hillier, C L Smith, R Jewell, M J Arthur & G Ross. (1985) Duodenal mucosa synthesis of prostaglandins in duodenal ulcer disease.. Gut 26:3, pages 237-240.
Crossref
ANDREAS ALY, KRISTER GRÉEN & CATJA JOHANSSON. (2009) Acid Instillation Increases Gastric Luminal Prostaglandin E 2 Output in Man . Acta Medica Scandinavica 218:5, pages 505-510.
Crossref
G. N. J. Tijtgat. 1985. Peptic Ulcer Disease: Basic and Clinical Aspects. Peptic Ulcer Disease: Basic and Clinical Aspects 143 153 .
S.J. Konturek, T. Brzozowski, T. Radecki & I. Pastucki. (1984) Comparison of gastric and intestinal antisecretory and protective effects of prostacyclin and its stable thia-amino-analogue (HOE 892) in consious rats. Prostaglandins 28:4, pages 443-453.
Crossref
David E. Bays & Roger Stables. 1984. 81 91 .
S. J. Konturek. 1984. IUPHAR 9th International Congress of Pharmacology London 1984. IUPHAR 9th International Congress of Pharmacology London 1984 341 344 .

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.