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Original Article

Comparative Pharmacokinetics of Metronidazole and Tinidazole and Their Tissue Penetration

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Pages 945-950 | Received 24 Jan 1985, Accepted 20 Feb 1985, Published online: 08 Jul 2009

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Laura J Dickey, Michael D Nailor & Jack D Sobel. (2009) Guidelines for the treatment of bacterial vaginosis: focus on tinidazole. Therapeutics and Clinical Risk Management 5, pages 485-489.
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I. Adamsson, C. Edlund & C.E. Nord. (2000) Microbial Ecology and Treatment of Helicobacter pylori Infections: Review. Journal of Chemotherapy 12:1, pages 5-16.
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A Klimowicz, A Nowak & S Bielecka-Grzela. (1993) Comparison of plasma and skin blister fluid concentrations of two orally administered nitroimidazoles. Journal of Dermatological Treatment 4:4, pages 199-201.
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Maria Saunders, Jinny Jeffery, Zoe Vincent, Ruth M. Ayling & Stephen Lewis. (2020) Relationship between faecal metronidazole and lactoferrin concentrations to clinical response of patients with Clostridioides difficile. European Journal of Clinical Microbiology & Infectious Diseases 39:9, pages 1781-1784.
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Samit Kumar Nandi, Samiran Bandyopadhyay, Piyali Das, Indranil Samanta, Prasenjit Mukherjee, Subhasis Roy & Biswanath Kundu. (2016) Understanding osteomyelitis and its treatment through local drug delivery system. Biotechnology Advances 34:8, pages 1305-1317.
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Werner Zimmerli & Parham Sendi. 2015. Mandell, Douglas, and Bennett's Principles and Practice of Infectious Diseases. Mandell, Douglas, and Bennett's Principles and Practice of Infectious Diseases 1328 1340.e3 .
P. Sendi & W. Zimmerli. (2012) Antimicrobial treatment concepts for orthopaedic device-related infection. Clinical Microbiology and Infection 18:12, pages 1176-1184.
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B. Spellberg & B. A. Lipsky. (2011) Systemic Antibiotic Therapy for Chronic Osteomyelitis in Adults. Clinical Infectious Diseases 54:3, pages 393-407.
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Christian Sköld, Susanne Winiwarter, Johan Wernevik, Fredrik Bergström, Leif Engström, Ruth Allen, Karl Box, John Comer, Jon Mole, Anders Hallberg, Hans Lennernäs, Torbjörn Lundstedt, Anna-Lena Ungell & Anders Karlén. (2006) Presentation of a Structurally Diverse and Commercially Available Drug Data Set for Correlation and Benchmarking Studies. Journal of Medicinal Chemistry 49:23, pages 6660-6671.
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Kelly A. Sprandel, Christopher A. Schriever, Susan L. Pendland, John P. Quinn, Mark H. Gotfried, Suzanne Hackett, Mary Beth Graham, Larry H. Danziger & Keith A. Rodvold. (2004) Pharmacokinetics and Pharmacodynamics of Intravenous Levofloxacin at 750 Milligrams and Various Doses of Metronidazole in Healthy Adult Subjects. Antimicrobial Agents and Chemotherapy 48:12, pages 4597-4605.
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Inger Adamsson, Carl Erik Nord, Per Lundquist, Svante Sjöstedt & Charlotta Edlund. (1999) Comparative effects of omeprazole, amoxycillin plus metronidazole versus omeprazole, clarithromycin plus metronidazole on the oral, gastric and intestinal microflora in Helicobacter pylori-infected patients. Journal of Antimicrobial Chemotherapy 44:5, pages 629-640.
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GODDARD, LOGAN, LAWES & SPILLER. (1999) Randomized controlled comparison of nitroimidazoles for the eradication of Helicobacter pylori and relief of ulcer-associated and non-ulcer dyspepsia . Alimentary Pharmacology & Therapeutics 13:5, pages 637-642.
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J.J. Espinosa-Aguirre, R.A. de la Torre, I. Lares-Asseff, J. Rubio, V. Dorado, M. Wong & J.M. Hernández. (1996) Bacterial mutagens in the urine of patients under tinidazole treatment. Mutation Research/Environmental Mutagenesis and Related Subjects 359:2, pages 133-140.
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A. Klimowicz, A. Nowak & S. Bielecka-Grzela. (1992) Penetration of tinidazole into skin blister fluid following its oral administration. European Journal of Clinical Pharmacology 43:5, pages 523-526.
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L. L. Ioannides‐Demos, C. Farmer, W. J. Spicer & A. J. McLean. (2008) DESIGN AND TRIAL OF A METRONIDAZOLE LOADING DOSE REGIMEN FOR PATIENTS UNDERGOING EMERGENCY SURGERY. Australian and New Zealand Journal of Surgery 59:12, pages 953-957.
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