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Original Article

Platelet Aggregation and Release of Atp in Patients with Hepatic Cirrhosis

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Pages 285-288 | Received 22 Mar 1984, Accepted 02 Jul 1984, Published online: 08 Jul 2009

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Pernille Just Vinholt, Anne-Mette Hvas, Christian Nielsen, Anna Cecilia Söderström, Ulrik Sprogøe, Annette Dam Fialla & Mads Nybo. (2018) Reduced platelet activation and platelet aggregation in patients with alcoholic liver cirrhosis. Platelets 29:5, pages 520-527.
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Articles from other publishers (26)

Alberto Zanetto, Elena Campello, Marco Senzolo & Paolo Simioni. (2023) The evolving knowledge on primary hemostasis in patients with cirrhosis: A comprehensive review. Hepatology Publish Ahead of Print.
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Ton Lisman. 2023. Cardio-Hepatology. Cardio-Hepatology 165 202 .
Karl Egan, Audrey Dillon, Eimear Dunne, Barry Kevane, Zita Galvin, Patricia Maguire, Dermot Kenny, Stephen Stewart & Fionnuala Ni Ainle. (2016) Increased soluble GPVI levels in cirrhosis: evidence for early in vivo platelet activation. Journal of Thrombosis and Thrombolysis 43:1, pages 54-59.
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Ton Lisman. 2017. Platelets in Thrombotic and Non-Thrombotic Disorders. Platelets in Thrombotic and Non-Thrombotic Disorders 1169 1181 .
Krishna N. Parekh, Jerome C. Crowley & Linda L. Liu. 2017. Anesthesia and Perioperative Care for Organ Transplantation. Anesthesia and Perioperative Care for Organ Transplantation 365 384 .
James A. Bynum, M. Adam Meledeo, Todd M. Getz, Armando C. Rodriguez, James K. Aden, Andrew P. Cap & Heather F. Pidcoke. (2016) Bioenergetic profiling of platelet mitochondria during storage: 4°C storage extends platelet mitochondrial function and viability. Transfusion 56:S1.
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A. Koneti Rao. 2013. Platelets. Platelets 1049 1073 .
Naoya Ikeda, Soichiro Murata, Takehito Maruyama, Takafumi Tamura, Reiji Nozaki, Takuya Kawasaki, Kiyoshi Fukunaga, Tatsuya Oda, Ryoko Sasaki, Masato Homma & Nobuhiro Ohkohchi. (2012) Platelet-derived adenosine 5′-triphosphate suppresses activation of human hepatic stellate cell: In vitro study. Hepatology Research 42:1, pages 91-102.
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F. Violi, S. Basili, V. Raparelli, P. Chowdary, A. Gatt & A.K. Burroughs. (2011) Patients with liver cirrhosis suffer from primary haemostatic defects? Fact or fiction?. Journal of Hepatology 55:6, pages 1415-1427.
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P. WITTERS, M. HOYLAERTS, K. FRESON, R. DE VOS, J. VAN PELT, F. NEVENS, C. VAN GEET & D. CASSIMAN. (2010) ADP‐degrading enzymes inhibit platelet activation in bile duct‐ligated rats. Journal of Thrombosis and Haemostasis 8:2, pages 360-368.
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Robert Fathke, Ze Peng, Basil Golding & Chava Kimchi‐Sarfaty. 2009. The Liver. The Liver 639 658 .
P. WITTERS, K. FRESON, C. VERSLYPE, K. PEERLINCK, M. HOYLAERTS, F. NEVENS, C. VAN GEET & D. CASSIMAN. (2008) Review article: blood platelet number and function in chronic liver disease and cirrhosis. Alimentary Pharmacology & Therapeutics 27:11, pages 1017-1029.
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Stephen Hardy & Ronald E. Kleinman. 2009. Liver Disease in Children. Liver Disease in Children 97 137 .
A. Koneti Rao. 2007. Platelets. Platelets 1051 1076 .
Randolph H. Steadman. (2004) Anesthesia for liver transplant surgery. Anesthesiology Clinics of North America 22:4, pages 687-711.
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A. Giacomini, P. Legovini, G. Gessoni, F. Antico, S. Valverde, M.M. Salvadego & F. Manoni. (2001) Platelet count and parameters determined by the Bayer ADVIA TM 120 in reference subjects and patients . Clinical & Laboratory Haematology 23:3, pages 181-186.
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Liliana Albornoz, Juan Carlos Bandi, Juan Carlos Otaso, Oscar Laudanno & Ricardo Mastai. (1999) Prolonged bleeding time in experimental cirrhosis: role of nitric oxide. Journal of Hepatology 30:3, pages 456-460.
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Giacomo Laffi, Sandro Cinotti, Ermino Filimberti, Giovanni Ciabattoni, Roberto Caporale, Fabio Marra, Lorenzo Melani, Alberto Grossi, Vinicio Carloni & Paolo Gentilini. (1996) Defective aggregation in cirrhosis is independent of in vivo platelet activation. Journal of Hepatology 24:4, pages 436-443.
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Jaime Pereira, Luigi Accatino, Margarita Pizarro, Verónica Mezzano, Angélica Ibañez & Diego Mezzano. (1995) In vivo effect of bile salts on platelet aggregation in rats. Thrombosis Research 80:4, pages 357-362.
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María J. Sánchez‐Roig, José Rivera, José M. Moraleda & Vicente Vicente García. (2006) Quantitative defect of glycoprotein ib in severe cirrhotic patients. American Journal of Hematology 45:1, pages 10-15.
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Giacomo Laffi, Fabio Marra, Paola Failli, Marco Ruggiero, Enrica cecchi, Vinicio Carloni, Alberto Giotti & Paolo Gentilini. (1993) Defective signal transduction in platelets from cirrhotics is associated with increased cyclic nucleotides. Gastroenterology 105:1, pages 148-156.
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D. Ferro, C. Quintarelli, M. Saliola, C. Alessandri, S. Basili, M.S. Bonavita & F. Violi. (1993) Prevalence of hyperfibrinolysis in patients with liver cirrhosis. Fibrinolysis 7:1, pages 59-62.
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Giacomo Laffi, Fabio Marra, Paolo Gresele, Paolo Romagnoli, Anna Palermo, Olga Bartolini, Antonella Simoni, Luisa Orlandi, Maria Laura Selli, Giuseppe G. Nenci & Paolo Gentilini. (1992) Evidence for a storage pool defect in platelets from cirrhotic patients with defective aggregation. Gastroenterology 103:2, pages 641-646.
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J. Lasierra, F. Bamao, G. Ceña, M.J. Aza, M.J. Morandeira, M.E. Barmo & J. González-Gallego. (1992) Changes of the fibrinolytic system in liver dysfunction: role of portal hypertension. Thrombosis Research 67:1, pages 15-21.
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K. Huber, Johannes C. Kirchheimer, Christian Korninger & Bernd R. Binder. (1991) Hepatic synthesis and clearance of components of the fibrinolytic system in healthy volunteers and in patients with different stages of liver cirrhosis. Thrombosis Research 62:5, pages 491-500.
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D.P. Mikhailidis, V. Fonseca, M.A. Barradas, R.A. Hutton, J.Y. Jeremy, O. Epstein, N. McIntyre & P. Dandona. (1988) Platelet aggregation and thromboxane A2 release in primary biliary cirrhosis and effect of D-penicillamine treatment. Prostaglandins, Leukotrienes and Essential Fatty Acids 31:3, pages 131-138.
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