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Scandinavian Journal of Gastroenterology Volume 21, 1986 - Issue 5
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Original Article

Effect of Pentagastrin on Gastric Acid Secretion in the Totally Isolated Vascularly Perfused Rat Stomach Stimulated with the Phosphodiesterase Inhibitor Isobutyl Methylxanthine

P. M. Kleveland Depts. of Medicine and Surgery, University and Regional Hospital in Trondheim, Trondheim, Norway
,
S. E. Haugen Depts. of Medicine and Surgery, University and Regional Hospital in Trondheim, Trondheim, Norway
&
H. L. Waldum Depts. of Medicine and Surgery, University and Regional Hospital in Trondheim, Trondheim, Norway
Pages 577-584 | Received 26 Aug 1985, Accepted 16 Dec 1985, Published online: 08 Jul 2009

Citations (27)

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R. Marrvik, A. K. Sandvik & H. L. Waldum. (1997) Evaluation of Biologic Gastrin Activity of Compound CI-988 in the Isolated, Vascularly Perfused Rat Stomach. Scandinavian Journal of Gastroenterology 32:6, pages 519-522.
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H. L. Waldum, M. Mignon, A. K. Sandvik & S. Bonfils. (1992) Biologic and Immunologic Gastrin Activity in Serum of Patients with Gastrinoma. Bioassay of Gastrin Activity in Serum. Scandinavian Journal of Gastroenterology 27:12, pages 1039-1044.
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P. M. Kleveland & H. L. Waldum. (1991) Session 3: The Gastrin Receptor Assay. Scandinavian Journal of Gastroenterology 26:sup180, pages 62-69.
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H. L. Waldum, T. Lehy, E. Brenna, A. K. Sandvik, H. Petersen, B. Schulze Søgnen, S. Bonfils & M. J. M. Lewin. (1991) Effect of the Histamine-1 Antagonist Astemizole Alone or with Omeprazole on Rat Gastric Mucosa. Scandinavian Journal of Gastroenterology 26:1, pages 23-35.
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S. E. Haugen, A. J. Douglas, B. Rønning, B. Walker, A. K. Sandvik, R. F. Murphy, D. T. Elmore & H. L. Waldum. (1989) Bioactivity Studies on New Gastrin Analogues. Scandinavian Journal of Gastroenterology 24:5, pages 577-580.
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A. K. Sandvik, J. J. Holst & H. L. Waldum. (1989) The Effect of Gastrin-Releasing Peptide on Acid Secretion and the Release of Gastrin, Somatostatin, and Histamine in the Totally Isolated, Vascularly Perfused Rat Stomach. Scandinavian Journal of Gastroenterology 24:1, pages 9-15.
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A. K. Sandvik, P. M. Kleveland & H. L. Waldum. (1987) Stimulated Pepsin Secretion after Omeprazole-Induced Acid Suppression in the Totally Isolated, Vascularly Perfused Rat Stomach. Scandinavian Journal of Gastroenterology 22:3, pages 362-366.
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P. M. Kleveland, H. L. Waldum & H. Larsson. (1987) Gastric Acid Secretion in the Totally Isolated, Vascularly Perfused Rat Stomach: A Selective Muscarinic-1 Agent Does, Whereas Gastrin Does Not, Augment Maximal Histamine-Stimulated Acid Secretion. Scandinavian Journal of Gastroenterology 22:6, pages 705-713.
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A. K. Sandvik, H. L. Waldum, P. M. Kleveland & B. Schulze Søgnen. (1987) Gastrin Produces an Immediate and Dose-Dependent Histamine Release Preceding Acid Secretion in the Totally Isolated, Vascularly Perfused Rat Stomach. Scandinavian Journal of Gastroenterology 22:7, pages 803-808.
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P. M. Kleveland, H. L. Waldum, H. Petersen & P. Sandberg. (1987) Pepsin Secretion by the Totally Isolated, Vascularly Perfused Rat Stomach. Scandinavian Journal of Gastroenterology 22:2, pages 165-173.
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Helge L. Waldum & Per M. Kleveland. (1986) Gastrointestinal Regulatory Peptides: Radioimmunoassay and Biological Activity. Scandinavian Journal of Gastroenterology 21:9, pages 1025-1028.
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P. M. Kleveland, H. L. Waldum, K. S. Bjerve & H. E. Fjøsne. (1986) Bioassay of Gastrin, Using the Totally Isolated, Vascularly Perfused Rat Stomach: A Biomodel Sensitive to Gastrin in Physiological Concentrations. Scandinavian Journal of Gastroenterology 21:8, pages 945-950.
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Articles from other publishers (15)

V. Fykse, E. Solligard, M. O. Bendheim, D. Chen, J. E. Gronbech, A. K. Sandvik & H. L. Waldum. (2006) ECL cell histamine mobilization and parietal cell stimulation in the rat stomach studied by microdialysis and electron microscopy. Acta Physiologica 186:1, pages 37-43.
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Vidar Fykse, David H Coy, Helge Lyder Waldum & Arne Kristian Sandvik. (2005) Somatostatin-receptor 2 (sst 2 )-mediated effects of endogenous somatostatin on exocrine and endocrine secretion of the rat stomach . British Journal of Pharmacology 144:3, pages 416-421.
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G.‐L. CUI, A. K. SANDVIK, B. MUNKVOLD & H. L. WALDUM. (2002) Glycine‐extended gastrin‐17 stimulates acid secretion only via CCK‐2 receptor‐induced histamine release in the totally isolated vascularly perfused rat stomach. Acta Physiologica Scandinavica 174:2, pages 125-130.
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P. Li, T.-M. Chang, D. Coy & W. Y. Chey. (2000) Inhibition of gastric acid secretion in rat stomach by PACAP is mediated by secretin, somatostatin, and PGE 2 . American Journal of Physiology-Gastrointestinal and Liver Physiology 278:1, pages G121-G127.
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Waldum, Mårvik, Grønbech, Sandvik & Aase. (2000) Oxyntic lesions may be provoked in the rat both by the process of acid secretion and also by gastric acidity. Alimentary Pharmacology & Therapeutics 14:1, pages 135-141.
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Joseph Carl Yarze. (1997) Physiology of gastric-acid secretion. The Lancet 350:9075, pages 446-447.
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Insik Chung, Ping Li, Kaeyol Lee, Tamin Chang & William Y. Chey. (1994) Dual inhibitory mechanism of secretin action on acid secretion in totally isolated, vascularly perfused rat stomach. Gastroenterology 107:6, pages 1751-1758.
Crossref
H. L. WALDUM, G. QVIGSTAD, R. MÅVIK, E. BRENNA, U. SYVERSEN & A. K. SANDVIK. (2007) The effect of tripotassium dicitrato bismuthate on the rat stomach. Alimentary Pharmacology & Therapeutics 8:4, pages 425-431.
Crossref
H. L. WALDUM, E. BRENNA, P. M. KLEVELAND, A. K. SANDVIK & U. SYVERSEN. (2007) Review article: the use of gastric acid‐inhibitory drugs—physiological and pathophysiological considerations. Alimentary Pharmacology & Therapeutics 7:6, pages 589-596.
Crossref
S.F. Moss, A. Waheed, K. Beardshall, J. Gill, D. Adamson, R. Unwin & J. Calam. (1993) Use of endoscopic biopsies and microelectrodes to study human gastric acid secretion in vitro. Neuropeptides 25:4, pages 265-269.
Crossref
K. Iwasa, A. K. Sandvik & H. L. Waldum. 1991. New Perspectives in Histamine Research. New Perspectives in Histamine Research 429 434 .
Arne K. Sandvik & Helge L. Waldum. (1990) Rat gastric histamine release: A sensitive gastrin bioassay. Life Sciences 46:6, pages 453-459.
Crossref
A. K. SANDVIK, J. KOFSTAD, J. J. HOLST & H. L. WALDUM. (2008) Ionized calcium influences gastrin stimulated histamine release and acid secretion, but not histamine stimulated acid output in the totally isolated vascularly perfused rat stomach. Acta Physiologica Scandinavica 134:3, pages 443-448.
Crossref
A.K. Sandvik & H.L. Waldum. (1988) The effect of somatostatin on baseline and stimulated acid secretion and vascular histamine release from the totally isolated vascularly perfused rat stomach. Regulatory Peptides 20:3, pages 233-239.
Crossref
A.K. Sandvik, P.M. Kleveland & H.L. Waldum. (1987) The effect of secretin on acid and pepsin secretion and gastrin release in the totally isolated vascularly perfused rat stomach. Regulatory Peptides 17:3, pages 143-149.
Crossref

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