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Scandinavian Journal of Gastroenterology Volume 21, 1986 - Issue 7
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Original Article

Double-Blind Crossover Study of Ranitidine and Placebo in Gastro-oesophageal Reflux Disease

K. E. Johansson Depts. of Surgery Pathology, and Otolaryngology, Linköping University, Linköping, and Surgical Clinic, Norrkoping County Hospital, Norrkoping, Sweden
,
B. Boeryd Depts. of Surgery Pathology, and Otolaryngology, Linköping University, Linköping, and Surgical Clinic, Norrkoping County Hospital, Norrkoping, Sweden
,
K. Johansson Depts. of Surgery Pathology, and Otolaryngology, Linköping University, Linköping, and Surgical Clinic, Norrkoping County Hospital, Norrkoping, Sweden
&
L. Tibbling Depts. of Surgery Pathology, and Otolaryngology, Linköping University, Linköping, and Surgical Clinic, Norrkoping County Hospital, Norrkoping, Sweden
Pages 769-778 | Received 20 Oct 1985, Accepted 28 Jan 1986, Published online: 08 Jul 2009

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F. Pace, G. Maconi, P. Molteni, M. Minguzzi & G. Bianchi Porro. (1995) Meta-Analysis of the Effect of Placebo on the Outcome of Medically Treated Reflux Esophagitis. Scandinavian Journal of Gastroenterology 30:2, pages 101-105.
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L. Elsborg & F. Jørgensen. (1991) Sucralfate versus Cimetidine in Reflux Oesophagitis: A Double-Blind Clinical Study. Scandinavian Journal of Gastroenterology 26:2, pages 146-150.
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Donald O. Castell & Aliza Holtz. (1989) Gastroesophageal reflux. Postgraduate Medicine 86:5, pages 141-148.
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H. R. Kofxz. (1989) Treatment of Reflux Esophagitis with Blockers, Antacids and Prokinetic Drugs:An Analysis of Randomized Clinical Trials. Scandinavian Journal of Gastroenterology 24:sup156, pages 25-36.
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S. G. M. Meuwissen & E. C. Klinkenberg-Knol. (1988) Treatment of Reflux Oesophagitis with H2-Receptor Antagonists. Scandinavian Journal of Gastroenterology 23:sup146, pages 201-213.
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L. Carling, J. Cronstedt, A. Engqvist, I. Kagevi, B. Nyström, L.-E. Svedberg, E. Thorhallsson, P. Unge & P.-E. Wingren. (1988) Sucralfate versus Placebo in Reflux Esophagitis: A Double-Blind Multicenter Study. Scandinavian Journal of Gastroenterology 23:9, pages 1117-1124.
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Articles from other publishers (32)

Kirsten E Sigterman, Bart van Pinxteren, Peter A Bonis, Joseph Lau & Mattijs E Numans. (2013) Short-term treatment with proton pump inhibitors, H2-receptor antagonists and prokinetics for gastro-oesophageal reflux disease-like symptoms and endoscopy negative reflux disease. Cochrane Database of Systematic Reviews.
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Paul Moayyedi, Jose Santana, Mostafiz Khan, Cathy Preston & Clare Donnellan. (2011) Medical treatments in the short term management of reflux oesophagitis. Cochrane Database of Systematic Reviews.
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Bart van Pinxteren, Kirsten E Sigterman, Peter Bonis, Joseph Lau & Mattijs E Numans. 1996. Cochrane Database of Systematic Reviews. Cochrane Database of Systematic Reviews.
Ting K Cheung, Benjamin C Y Wong & Shiu K Lam. (2008) Gastro-Oesophageal Reflux Disease in Asia. Drugs 68:4, pages 399-406.
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Joel E. Richter. 2008. Pearson's Thoracic and Esophageal Surgery. Pearson's Thoracic and Esophageal Surgery 192 201 .
Paul Moayyedi, Jose Santana, Mostafiz Khan, Cathy Preston & Clare Donnellan. 1996. Cochrane Database of Systematic Reviews. Cochrane Database of Systematic Reviews.
Bart van Pinxteren, Kirsten E Sigterman, Peter Bonis, Joseph Lau & Mattijs E Numans. 1996. Cochrane Database of Systematic Reviews. Cochrane Database of Systematic Reviews.
Paul Moayyedi & Nicholas J Talley. (2006) Gastro-oesophageal reflux disease. The Lancet 367:9528, pages 2086-2100.
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B van Pinxteren, ME Numans, PA Bonis & J Lau. 1996. Cochrane Database of Systematic Reviews. Cochrane Database of Systematic Reviews.
Bart Pinxteren, Mattijs E. Numans, Joseph Lau, Niek J. Wit, A. Pali S. Hungin & Peter A. L. Bonis. (2003) Short-term treatment of gastroesophageal reflux disease. Journal of General Internal Medicine 18:9, pages 755-763.
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Earnest, Robinson, Rodriguez‐Stanley, Ciociola, Jaffe, Silver, Kleoudis & Murdock. (2001) Managing heartburn at the ‘base’ of the GERD ‘iceberg’: effervescent ranitidine 150 mg b.d. provides faster and better heartburn relief than antacids. Alimentary Pharmacology & Therapeutics 14:7, pages 911-918.
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Escourrou, Deprez, Saggioro, Geldof, Fischer & Maier. (2001) Maintenance therapy with pantoprazole 20 mg prevents relapse of reflux oesophagitis. Alimentary Pharmacology & Therapeutics 13:11, pages 1481-1491.
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Yoshihisa ShibataMDMD, Yuji NimuraMDMD, Sumio ToyodaMDMD, Akihiro YasuiMDMD & Takeo KawamuraMDMD. (1998) Acid Reflux Test for Gastroesophageal Reflux After Distal Gastrectomy: Diagnosis and Clinical Effect of Cisapride. Journal of the American College of Surgeons 186:5, pages 596-600.
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Debra McCarty-Dawson, Samuel O. Sue, Betsy Morrill & Robert H. MurdockJrJr. (1996) Ranitidine versus cimetidine in the healing of erosive esophagitis. Clinical Therapeutics 18:6, pages 1150-1160.
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KENNETH R. DE VAULT & DONALD O. CASTELL. (1994) Current Diagnosis and Treatment of Gastroesophageal Reflux Disease. Mayo Clinic Proceedings 69:9, pages 867-876.
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A. B. R. THOMSON, L. BABIUK, P. KIRDEIKIS, L. ZUK, B. MARRIAGE & K. BOWES. (2007) A dose‐ranging study of ranitidine and its effect on intragastric and intra‐oesophageal acidity in subjects with gastro‐oesophageal reflux disease. Alimentary Pharmacology & Therapeutics 8:4, pages 443-451.
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C. ARVANITAKIS, A. NIKOPOULOS, A. THEOHARIDIS, E. GIANNOULIS, I. VAGIOS, H. ANTHOPOULOU, D. MICHAILIDIS & A. TOURKANTONIS. (2007) Cisapride and ranitidine in the treatment of gastro‐oesophageal reflux disease—a comparative randomized double‐blind trial. Alimentary Pharmacology & Therapeutics 7:6, pages 635-641.
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Y. Vandenplas, A. Ashkenazi, D. Belli, N. Boige, J. Bouquet, S. Cadranel, J. P. Cezard, S. Cucchiara, C. Dupont, K. Geboes, F. Gottrand, H. S. A. Heymans, C. Jasinski, C. M. F. Kneepkens, S. Koletzko, P. Milla, J. F. Mougenot, D. Nusslé, J. Navarro, S. J. Newell, E. Olafsdottir, S. Peeters, A. Ravelli, I. Polanco, B. K. Sandhu & J. Tolboom. (1993) A proposition for the diagnosis and treatment of gastro-oesophageal reflux disease in children: A report from a working group on gastro-oesophageal reflux disease. European Journal of Pediatrics 152:9, pages 704-711.
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S. J. SONTAG. (2007) Rolling review: gastro‐oesophageal reflux disease. Alimentary Pharmacology & Therapeutics 7:3, pages 293-312.
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Toshikazu Sekiguchi, Tsutomu Matsuzaki, Tsutomu Horikoshi & Motoyasu Kusano. (2012) Open Study of the Clinical Effects of Lansoprazole in the Treatment of Reflux Oesophagitis. Drug Investigation 4:5, pages 422-434.
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Martin J. Collen & Richard M. Strong. (1992) Comparison of omeprazole and ranitidine in treatment of refractory gastroesophageal reflux disease in patients with gastric acid hypersecretion. Digestive Diseases and Sciences 37:6, pages 897-903.
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David A. Johnson. (1992) Medical therapy for gastroesophageal reflux disease. The American Journal of Medicine 92:5, pages S88-S97.
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N J Bell & R H Hunt. (1992) Role of gastric acid suppression in the treatment of gastro-oesophageal reflux disease.. Gut 33:1, pages 118-124.
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William R. Garnett & George Earl DukesJr.Jr.. 1992. Applied Therapeutics. Applied Therapeutics 375 396 .
James A. Koufman. (1991) The Otolaryngologic Manifestations of Gastroesophageal Reflux Disease (GERD): A Clinical Investigation of 225 Patients Using Ambulatory 24-Hour pH Monitoring and an Experimental Investigation of the Role of Acid and Pepsin in the Development of Laryngeal. The Laryngoscope 101, pages 1-78.
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P J Howard, L Maher, A Pryde & R C Heading. (1991) Symptomatic gastro-oesophageal reflux, abnormal oesophageal acid exposure, and mucosal acid sensitivity are three separate, though related, aspects of gastro-oesophageal reflux disease.. Gut 32:2, pages 128-132.
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Stephen j. Sontag. (1990) The Medical Management of Reflux Esophagitis. Gastroenterology Clinics of North America 19:3, pages 683-712.
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J. P. Galmiche, B. Fraitag, B. Filoche, M. Evreux, J. Vitaux, P. Zeitoun, J. Fournet & J. C. Soule. (1990) Double-blind comparison of cisapride and cimetidine in treatment of reflux esophagitis. Digestive Diseases and Sciences 35:5, pages 649-655.
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Martin J. Collen, James H. Lewis & Stanley B. Benjamin. (1990) Gastric acid hypersecretion in refractory gastroesophageal reflux disease. Gastroenterology 98:3, pages 654-661.
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M. Deakin & J. G. Temple. (1988) THERAPEUTIC PROGRESS—REVIEW XXXIII: ARE WE MAKING PROGRESS IN THE DRUG TREATMENT OF OESOPHAGEAL DISEASE?. Journal of Clinical Pharmacy and Therapeutics 13:6, pages 365-374.
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T Havelund, L S Laursen, E Skoubo-Kristensen, B N Andersen, S A Pedersen, K B Jensen, C Fenger, F Hanberg-Sorensen & K Lauritsen. (1988) Omeprazole and ranitidine in treatment of reflux oesophagitis: double blind comparative trial. BMJ 296:6615, pages 89-92.
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G.N.J. Tytgat & C.Y. Nio. (1987) 4 The medical therapy of reflux oesophagitis. Baillière's Clinical Gastroenterology 1:4, pages 791-807.
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